Pericallosal Moustache Thrombophlebitis

Pericallosal moustache thrombophlebitis may sound complicated, but in simple terms, it refers to inflammation and clotting of the veins near the corpus callosum, a part of the brain. In this article, we’ll break down everything you need to know about this condition, from its causes and symptoms to treatments and prevention measures.

Pericallosal moustache thrombophlebitis is a medical term describing inflammation and clot formation in the veins around the corpus callosum, a structure in the brain that connects the left and right cerebral hemispheres.


There are no specific types of pericallosal moustache thrombophlebitis. It typically presents as a single condition with variations in severity.


  1. Dehydration: Lack of proper hydration can lead to thickening of the blood, increasing the risk of clot formation.
  2. Trauma to the head: Injury to the head can damage blood vessels, leading to inflammation and clotting.
  3. Infections: Certain infections, such as meningitis, can trigger inflammation of the blood vessels in the brain.
  4. Genetic factors: Some individuals may have a genetic predisposition to developing blood clots.
  5. Hormonal changes: Changes in hormone levels, such as those occurring during pregnancy or with hormonal therapies, can increase the risk of clot formation.
  6. Smoking: Smoking tobacco can damage blood vessels and promote clot formation.
  7. Obesity: Being overweight or obese can strain the cardiovascular system, increasing the risk of clotting.
  8. Certain medications: Some medications, such as hormonal contraceptives or hormone replacement therapy, can increase the risk of blood clots.
  9. Sedentary lifestyle: Lack of physical activity can contribute to poor blood circulation and increase the risk of clot formation.
  10. Underlying medical conditions: Conditions like cancer, autoimmune disorders, and inflammatory diseases can predispose individuals to develop thrombophlebitis.
  11. Prolonged sitting or immobility: Long periods of sitting, such as during long flights or bed rest, can slow down blood flow and increase the risk of clot formation.
  12. Surgery: Certain surgical procedures, especially those involving the lower extremities or abdomen, can increase the risk of thrombophlebitis.
  13. Pregnancy and childbirth: Pregnancy and childbirth pose a risk of developing blood clots due to hormonal changes and pressure on blood vessels.
  14. Age: Older adults are at higher risk of developing thrombophlebitis due to age-related changes in blood vessels.
  15. Inflammatory bowel disease: Conditions like Crohn’s disease or ulcerative colitis can increase inflammation throughout the body, including blood vessels.
  16. Varicose veins: Varicose veins are swollen, twisted veins that can increase the risk of blood clots.
  17. Heart conditions: Certain heart conditions, such as atrial fibrillation, can disrupt blood flow and promote clot formation.
  18. High blood pressure: Hypertension can damage blood vessels and increase the risk of thrombophlebitis.
  19. Diabetes: Diabetes can damage blood vessels and impair circulation, increasing the risk of clot formation.
  20. Hypercoagulable disorders: Conditions that cause the blood to clot more easily, such as Factor V Leiden mutation or antiphospholipid syndrome, can increase the risk of thrombophlebitis.


  1. Headache: Persistent headache, often described as throbbing or pulsating.
  2. Confusion: Difficulty concentrating or understanding information.
  3. Visual disturbances: Blurred vision, double vision, or vision loss in one or both eyes.
  4. Seizures: Uncontrolled electrical activity in the brain, resulting in convulsions or loss of consciousness.
  5. Weakness or numbness: Weakness or numbness in one side of the body, often accompanied by difficulty moving limbs.
  6. Difficulty speaking: Slurred speech or difficulty forming words.
  7. Loss of coordination: Difficulty maintaining balance or performing coordinated movements.
  8. Changes in behavior: Sudden changes in mood or behavior, such as irritability or agitation.
  9. Sensory changes: Altered sensations, such as tingling or prickling sensations in the limbs.
  10. Fatigue: Persistent tiredness or lack of energy.
  11. Fever: Elevated body temperature, often indicating an underlying infection.
  12. Nausea and vomiting: Feeling sick to the stomach and vomiting.
  13. Neck stiffness: Difficulty bending the neck forward due to stiffness and pain.
  14. Sensitivity to light: Discomfort or pain when exposed to bright lights.
  15. Difficulty swallowing: Trouble swallowing food or liquids.
  16. Dizziness or lightheadedness: Feeling faint or dizzy, often accompanied by a sensation of spinning.
  17. Changes in consciousness: Altered level of consciousness, ranging from drowsiness to coma.
  18. Personality changes: Changes in personality traits or behaviors.
  19. Hemiparesis: Weakness on one side of the body, affecting arm, leg, or face muscles.
  20. Loss of consciousness: Passing out or fainting due to decreased blood flow to the brain.

Diagnostic Tests:

  1. Magnetic Resonance Imaging (MRI): This imaging test uses powerful magnets and radio waves to create detailed images of the brain, helping detect abnormalities such as blood clots.
  2. Computed Tomography (CT) scan: CT scans combine multiple X-ray images to produce cross-sectional images of the brain, aiding in the diagnosis of thrombophlebitis.
  3. Cerebral Angiography: This procedure involves injecting contrast dye into the blood vessels of the brain and taking X-ray images to visualize blood flow and detect abnormalities.
  4. Blood tests: Blood tests can measure levels of clotting factors and markers of inflammation, helping diagnose thrombophlebitis.
  5. Lumbar Puncture: Also known as a spinal tap, this procedure involves collecting cerebrospinal fluid from the spinal canal to check for signs of infection or bleeding in the brain.
  6. Electroencephalogram (EEG): EEG records electrical activity in the brain, helping diagnose seizures or other neurological abnormalities.
  7. Doppler Ultrasound: This non-invasive test uses sound waves to evaluate blood flow through the veins and detect blood clots.
  8. Blood Coagulation Tests: These tests measure the time it takes for blood to clot, helping assess the risk of thrombosis.
  9. Transcranial Doppler (TCD) Ultrasound: TCD ultrasound measures blood flow velocity in the arteries of the brain, aiding in the diagnosis of stroke or vascular abnormalities.
  10. Neurological Examination: A comprehensive neurological examination assesses cognitive function, motor skills, and sensory abilities, helping detect abnormalities associated with thrombophlebitis.

Non-Pharmacological Treatments:

  1. Rest: Resting the brain and avoiding strenuous activities can help reduce symptoms and promote healing.
  2. Hydration: Drinking plenty of fluids can help prevent dehydration, which can contribute to clot formation.
  3. Healthy Diet: Eating a balanced diet rich in fruits, vegetables, and whole grains can help support overall brain health.
  4. Stress Management: Managing stress through techniques like meditation, yoga, or deep breathing exercises can help reduce inflammation and promote healing.
  5. Physical Therapy: Physical therapy can help improve strength, balance, and coordination, especially if there are any neurological deficits.
  6. Occupational Therapy: Occupational therapy can help individuals regain independence in daily activities and improve cognitive function.
  7. Speech Therapy: Speech therapy can help individuals improve communication skills if they’re affected by speech or language problems.
  8. Supportive Care: Providing emotional support and encouragement to individuals and their families can help cope with the challenges of pericallosal moustache thrombophlebitis.
  9. Assistive Devices: Using assistive devices like walkers or wheelchairs can help individuals maintain mobility and independence.
  10. Cognitive Rehabilitation: Cognitive rehabilitation programs can help improve memory, attention, and problem-solving skills.


  1. Anticoagulants: These medications help prevent blood clots from forming or getting bigger.
  2. Antiplatelet Agents: These medications help prevent platelets from clumping together and forming clots.
  3. Analgesics: These medications can help relieve pain and discomfort.
  4. Anticonvulsants: These medications help prevent or control seizures.
  5. Antidepressants: These medications can help manage depression or anxiety that may occur as a result of pericallosal moustache thrombophlebitis.
  6. Antipyretics: These medications help reduce fever.
  7. Antiemetics: These medications help relieve nausea and vomiting.
  8. Muscle Relaxants: These medications can help reduce muscle stiffness or spasms.
  9. Corticosteroids: These medications can help reduce inflammation in the brain.
  10. Antibiotics: If the thrombophlebitis is caused by an infection, antibiotics may be prescribed to treat the underlying infection.


  1. Thrombectomy: In severe cases, surgery may be necessary to remove a blood clot from the brain’s blood vessels.
  2. Craniotomy: This surgical procedure involves removing part of the skull to access the brain and remove any blood clots or relieve pressure on the brain.
  3. Ventriculostomy: In cases where there’s a buildup of cerebrospinal fluid in the brain, a ventriculostomy may be performed to drain the fluid and relieve pressure.
  4. Shunt Placement: If there’s a blockage in the brain’s ventricular system, a shunt may be implanted


Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.