Pericallosal Moustache Arteriosclerosis

Pericallosal Moustache Arteriosclerosis (PMA) may sound complex, but understanding it is crucial for maintaining brain health. In this guide, we’ll break down PMA in simple terms, covering its types, causes, symptoms, diagnostic tests, treatments, prevention, and when to seek medical help.


PMA can manifest in different ways, including focal or diffuse arteriosclerosis. Focal arteriosclerosis affects specific areas, while diffuse arteriosclerosis spreads across broader brain regions.


Various factors contribute to PMA, such as:

  1. High blood pressure
  2. High cholesterol levels
  3. Smoking
  4. Diabetes
  5. Obesity
  6. Sedentary lifestyle
  7. Genetic predisposition
  8. Aging
  9. Poor diet
  10. Lack of exercise
  11. Stress
  12. Excessive alcohol consumption
  13. Drug abuse
  14. Sleep apnea
  15. Thyroid disorders
  16. Kidney diseases
  17. Inflammation
  18. Autoimmune diseases
  19. Environmental factors
  20. Radiation exposure


Signs of PMA may include:

  1. Headaches
  2. Memory loss
  3. Confusion
  4. Difficulty concentrating
  5. Mood swings
  6. Speech problems
  7. Vision changes
  8. Weakness or numbness in limbs
  9. Coordination difficulties
  10. Dizziness
  11. Fatigue
  12. Personality changes
  13. Depression
  14. Anxiety
  15. Trouble sleeping
  16. Balance problems
  17. Seizures
  18. Slurred speech
  19. Tremors
  20. Paralysis

Diagnostic Tests:

Doctors may use various tests to diagnose PMA, including:

  1. MRI (Magnetic Resonance Imaging)
  2. CT scan (Computed Tomography)
  3. Angiography
  4. Doppler ultrasound
  5. Blood tests
  6. Electroencephalogram (EEG)
  7. Neuropsychological tests
  8. Neurological examination
  9. Lumbar puncture
  10. Cognitive assessments
  11. Genetic testing
  12. Eye examination
  13. PET scan (Positron Emission Tomography)
  14. SPECT scan (Single Photon Emission Computed Tomography)
  15. Cerebral angiogram
  16. Transcranial Doppler
  17. Carotid ultrasound
  18. Electrocardiogram (ECG)
  19. Holter monitor
  20. Mini-Mental State Examination (MMSE)

Non-Pharmacological Treatments:

Managing PMA without medication involves:

  1. Lifestyle modifications (healthy diet, exercise)
  2. Smoking cessation programs
  3. Stress reduction techniques (meditation, yoga)
  4. Cognitive behavioral therapy (CBT)
  5. Physical therapy
  6. Occupational therapy
  7. Speech therapy
  8. Nutritional counseling
  9. Sleep hygiene improvements
  10. Support groups
  11. Brain training exercises
  12. Music therapy
  13. Art therapy
  14. Pet therapy
  15. Acupuncture
  16. Massage therapy
  17. Hydrotherapy
  18. Transcranial magnetic stimulation (TMS)
  19. Biofeedback
  20. Assistive devices (cane, walker)


Medications may be prescribed to manage PMA symptoms, including:

  1. Antihypertensives
  2. Statins
  3. Antiplatelet drugs
  4. Anticoagulants
  5. Antidepressants
  6. Anxiolytics
  7. Anticonvulsants
  8. Memory enhancers
  9. Stimulants
  10. Dopamine agonists


In severe cases, surgical interventions may be necessary, such as:

  1. Carotid endarterectomy
  2. Angioplasty and stenting
  3. Bypass surgery
  4. Aneurysm clipping
  5. Craniotomy
  6. Stereotactic radiosurgery
  7. Deep brain stimulation
  8. Vagus nerve stimulation
  9. Corpus callosotomy
  10. Temporal lobectomy


To reduce the risk of PMA, consider:

  1. Maintaining a healthy weight
  2. Exercising regularly
  3. Eating a balanced diet
  4. Monitoring blood pressure and cholesterol levels
  5. Avoiding smoking and excessive alcohol consumption
  6. Managing stress effectively
  7. Getting regular check-ups
  8. Treating underlying health conditions promptly
  9. Sleeping well
  10. Protecting the head from injury

When to See Doctors:

Consult a healthcare professional if you experience any symptoms mentioned above or have concerns about brain health. Early detection and intervention can significantly improve outcomes.


Pericallosal Moustache Arteriosclerosis is a complex condition, but understanding its basics empowers individuals to take proactive steps towards prevention and management. By adopting a healthy lifestyle, seeking timely medical advice, and adhering to treatment plans, one can mitigate the impact of PMA and enhance overall well-being.


Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.