Pericallosal Moustache Obstruction:

Pericallosal moustache obstruction is a condition that affects the flow of fluid in the brain, leading to various symptoms and potential complications. In this comprehensive guide, we’ll explore what pericallosal moustache obstruction is, its causes, symptoms, diagnostic tests, treatments, and preventive measures in simple language for better understanding.

Pericallosal moustache obstruction occurs when there’s a blockage in the fluid-filled spaces (ventricles) of the brain, particularly near the corpus callosum—a bridge-like structure that connects the brain’s two halves. This obstruction can disrupt the normal flow of cerebrospinal fluid (CSF), leading to a range of symptoms.

Types of Pericallosal Moustache Obstruction:

  1. Non-communicating hydrocephalus: Blockage occurs within the ventricular system, hindering CSF flow.
  2. Communicating hydrocephalus: Blockage happens outside the ventricular system, affecting CSF absorption.

Causes of Pericallosal Moustache Obstruction:

  1. Congenital anomalies (present at birth)
  2. Brain tumors or cysts
  3. Infections like meningitis
  4. Traumatic brain injury
  5. Intraventricular hemorrhage (bleeding within brain ventricles)
  6. Aqueductal stenosis (narrowing of the cerebral aqueduct)
  7. Chiari malformation (brain tissue extends into the spinal canal)
  8. Arachnoid cysts (fluid-filled sacs between the brain and skull)
  9. Dandy-Walker syndrome (malformation of the brain’s cerebellum)
  10. Tumor obstruction of CSF pathways
  11. Neurocysticercosis (parasitic infection of the brain)
  12. Brain abscesses
  13. Blocked ventriculostomy (surgical drainage procedure)
  14. Idiopathic (unknown cause)
  15. Brain hemorrhage
  16. Brain surgery complications
  17. Radiation therapy side effects
  18. Central nervous system (CNS) infections
  19. Ventricular septal defects (abnormal connections between brain ventricles)
  20. Subarachnoid hemorrhage (bleeding in the space surrounding the brain)

Symptoms of Pericallosal Moustache Obstruction:

  1. Headache
  2. Nausea and vomiting
  3. Blurred or double vision
  4. Changes in mood or behavior
  5. Difficulty walking or balancing
  6. Cognitive impairment
  7. Urinary incontinence
  8. Fatigue or lethargy
  9. Seizures
  10. Memory problems
  11. Irritability
  12. Delayed development (in infants)
  13. Sleep disturbances
  14. Poor coordination
  15. Personality changes
  16. Decreased appetite
  17. Sensory changes (e.g., numbness or tingling)
  18. Slurred speech
  19. Difficulty concentrating
  20. Poor academic performance

Diagnostic Tests for Pericallosal Moustache Obstruction:

  1. MRI (Magnetic Resonance Imaging) scan
  2. CT (Computed Tomography) scan
  3. Ultrasound of the brain
  4. Lumbar puncture (spinal tap) to analyze CSF
  5. Endoscopic third ventriculostomy (ETV)
  6. Cisternography (imaging of CSF pathways)
  7. Neurological examination
  8. Intracranial pressure monitoring
  9. Neuropsychological testing
  10. Visual evoked potentials (VEP)
  11. Electroencephalogram (EEG)
  12. Blood tests
  13. Genetic testing for congenital conditions
  14. X-rays of the skull
  15. Doppler ultrasound
  16. Ophthalmological examination
  17. CSF flow studies
  18. Brain biopsy (rarely needed)
  19. Neuroimaging with contrast dye
  20. Neuropsychiatric assessment

Non-Pharmacological Treatments for Pericallosal Moustache Obstruction:

  1. Ventriculoperitoneal (VP) shunt surgery to divert CSF
  2. Endoscopic third ventriculostomy (ETV) to create a new CSF pathway
  3. Optic nerve sheath fenestration (ONSF) to relieve intracranial pressure
  4. Rehabilitation therapy (physical, occupational, speech therapy)
  5. Lifestyle modifications (healthy diet, regular exercise)
  6. Cognitive-behavioral therapy (CBT) for mood and behavior management
  7. Assistive devices for mobility (canes, walkers)
  8. Special education services for children with developmental delays
  9. Nutritional counseling for optimal brain health
  10. Hydrotherapy for pain relief and muscle relaxation
  11. Acupuncture or acupressure for symptom management
  12. Chiropractic care for spinal alignment and nerve function
  13. Yoga or meditation for stress reduction and relaxation
  14. Biofeedback therapy for symptom control
  15. Hyperbaric oxygen therapy to improve brain oxygenation
  16. Music therapy for emotional expression and relaxation
  17. Art therapy for cognitive stimulation and self-expression
  18. Massage therapy for muscle tension and pain relief
  19. Craniosacral therapy for gentle manipulation of the skull and spine
  20. Support groups for patients and caregivers

Drugs for Pericallosal Moustache Obstruction:

  1. Acetazolamide (Diamox) to reduce CSF production
  2. Furosemide (Lasix) to decrease intracranial pressure
  3. Mannitol (Osmitrol) for osmotic diuresis and brain edema reduction
  4. Corticosteroids (prednisone, dexamethasone) for inflammation control
  5. Antiepileptic drugs (phenytoin, levetiracetam) for seizure management
  6. Antidepressants (SSRIs, SNRIs) for mood stabilization
  7. Anxiolytics (benzodiazepines) for anxiety relief
  8. Muscle relaxants (baclofen, tizanidine) for spasticity management
  9. Sleep aids (zolpidem, trazodone) for insomnia treatment
  10. Antiemetics (ondansetron, metoclopramide) for nausea and vomiting control
  11. Stimulants (methylphenidate, modafinil) for fatigue management
  12. Antipsychotics (quetiapine, risperidone) for behavioral disturbances
  13. Nootropics (piracetam, modafinil) for cognitive enhancement
  14. Pain relievers (acetaminophen, ibuprofen) for headache management
  15. Dopamine agonists (pramipexole, ropinirole) for movement disorders
  16. Beta-blockers (propranolol) for migraine prevention
  17. Anticholinergics (oxybutynin, tolterodine) for urinary incontinence
  18. Neurotrophic agents (nerve growth factor) for neuroprotection
  19. Anti-inflammatory drugs (ibuprofen, naproxen) for pain and inflammation
  20. Vasopressors (norepinephrine, phenylephrine) for hypotension management

Surgeries for Pericallosal Moustache Obstruction

  1. Carotid endarterectomy
  2. Angioplasty and stenting
  3. Thrombectomy
  4. Craniotomy
  5. Aneurysm clipping
  6. Ventriculoperitoneal shunting
  7. Deep brain stimulation
  8. Radiofrequency ablation
  9. CyberKnife radiosurgery
  10. Gamma Knife radiosurgery

Preventive Measures for Pericallosal Moustache Obstruction

  1. Maintain a healthy lifestyle
  2. Eat a balanced diet low in saturated fats and cholesterol
  3. Exercise regularly
  4. Manage stress effectively
  5. Control blood pressure and cholesterol levels
  6. Quit smoking and limit alcohol consumption
  7. Monitor and manage diabetes
  8. Stay hydrated
  9. Get regular check-ups and screenings
  10. Follow prescribed medications and treatments

When to See a Doctor

It’s important to seek medical attention if you experience any symptoms suggestive of pericallosal moustache obstruction, such as sudden or severe headaches, weakness or numbness in the limbs, difficulty speaking or understanding speech, vision problems, or changes in consciousness. Early diagnosis and treatment can help prevent complications and improve outcomes.


Pericallosal Moustache Obstruction is a serious condition that requires prompt medical attention. By understanding its causes, symptoms, and treatment options, you can take proactive steps to protect your brain health and overall well-being. Remember to consult with healthcare professionals for personalized advice and care.


Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.