Mirogabalin – Uses, Dosage, Side Effects, Interactions

Mirogabalin has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain. Mirogabalin is a medication designed to treat neuropathic pain. It belongs to the group of drugs that act on specific receptors in the brain and nervous system. Mirogabalin acts by binding to the α2δ Read More >>>>

Enprostil – Uses, Dosage, Side Effects, Interactions

Enprostil is a synthetic prostaglandin designed to resemble dinoprostone. Enprostil was found to be a highly potent inhibitor of gastric HCl secretion.[rx] It is an analog of prostaglandin E2 but unlike this prostaglandin, which binds to and activates all four cellular receptors viz., EP1, EP2, EP3, and EP4 receptors, enprostil is a more selective receptor agonist in that it binds to and activates primarily the EP3 receptor.[rx] Consequently, enprostil is expected Read More >>>>

Tafasitamab – Uses, Dosage, Side Effects, Interactions

Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies.[rx] It is produced using recombinant DNA technology in Chinese hamster ovary cells and contains an IgG1/2 hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity relative to non-engineered anti-CD19 antibodies.[rx],[rx] The CD19 surface protein Read More >>>>

Mogamulizumab – Uses, Dosage, Side Effects, Interaction

Mogamulizumab is a CCR4-targeted immuno-oncology drug. It is intended to deplete CCR4-expressing Treg cells in the tumor microenvironment so as to release Teff cells from Treg-mediated suppression and facilitate tumor cell killing. However, it also targets intratumoral Treg cells that serve other vital immune cell functions and can induce serious side effects such as dermatologic Read More >>>>

Mobocertinib – Uses, Dosage, Side Effects, Interaction

Mobocertinib is a Kinase Inhibitor. The mechanism of action of mobocertinib is as a HER1 Antagonist and Cytochrome P450 3A Inducer. Mobocertinib is an inhibitor of EGFR that irreversibly binds to and inhibits EGFR exon 20 insertion mutations at lower concentrations than wild-type EGFR proteins, exerting a pharmacologic effect on mutant variants at concentrations 1.5- Read More >>>>

Mitoxantrone – Uses, Dosage, Side Effects, Interaction

Mitoxantrone is an antineoplastic antibiotic that is used in the treatment of acute leukemia, lymphoma, and prostate and breast cancer, but also for late-stage, severe multiple sclerosis. Mitoxantrone therapy is often accompanied by mild to moderate elevations in serum aminotransferase levels, but in typical doses, it rarely causes clinically apparent, acute liver injury. Mitoxantrone is Read More >>>>

Mirvetuximab – Uses, Dosage, Side Effects, Interaction

Mirvetuximab Soravtansine is an immunoconjugate consisting of the humanized monoclonal antibody M9346A against folate receptor 1 (FOLR1) conjugated, via the disulfide-containing cleavable linker sulfo-SPDB, to the cytotoxic maytansinoid DM4, with potential antineoplastic activity. The anti-FOLR1 monoclonal antibody moiety of mirvetuximab soravtansine targets and binds to the cell surface antigen FOLR1. After antibody-antigen interaction and internalization, the immunoconjugate releases DM4, which binds to Read More >>>>

Midostaurin – Uses, Dosage, Side Effects, Interaction

Midostaurin is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3) which is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. Midostaurin is associated with a moderate rate of serum aminotransferase elevations during therapy and is suspected to cause rare instances of clinically apparent acute liver Read More >>>>

Methylnaltrexone Bromide – Uses, Dosage, Side Effects, Interaction

Methylnaltrexone is a methyl derivative of noroxymorphone with selective, opioid-receptor antagonistic activity. Methylnaltrexone is a member of phenanthrenes. Methylnaltrexone displaces opioids from peripheral opioid receptors in the gastrointestinal tract, the bladder, and the skin, resulting in decreases in opioid-related constipation, urinary retention, and pruritis, respectively. Methylnaltrexone does not cross the blood-brain barrier and does not affect Read More >>>>

Mercaptoethanesulfonic Acid – Uses, Dosage, Side Effects

2-mercaptoethanesulfonic acid is a Cytoprotective Agent. Coenzyme M is an organosulfonic acid consisting of a sulfonic acid having a 2-mercaptoethanol group attached to sulfur. It has a role as a coenzyme. It is an organosulfonic acid and a thiol. It is a conjugate acid of a coenzyme M(1-). Coenzyme M (commonly known by its salt form, Read More >>>>

Mesna – Uses, Dosage, Side Effects, Interactions

2-mercaptoethanesulfonic acid is a Cytoprotective Agent. Coenzyme M is an organosulfonic acid consisting of a sulfonic acid having a 2-mercaptoethanol group attached to sulfur. It has a role as a coenzyme. It is an organosulfonic acid and a thiol. It is a conjugate acid of a coenzyme M(1-). Coenzyme M (commonly known by its salt form, Read More >>>>

Trametinib – Uses, Dosage, Side Effects, Interaction

Trametinib is a dual-kinase inhibitor that is used in the treatment of advanced malignant melanoma, usually in combination with dabrafenib. Trametinib therapy is associated with transient elevations in serum aminotransferase and alkaline phosphatase levels during therapy but has yet to be linked cases of clinically apparent acute liver injury. Trametinib is an orally bioavailable inhibitor Read More >>>>