Pyogenic Granuloma

Pyogenic granuloma is a type of skin lesion that is characterized by a raised, red, and often ulcerated bump. The term “pyogenic” refers to the presence of pus, and “granuloma” refers to the formation of small nodules. This type of skin lesion is not a true granuloma, but rather a benign, vascular lesion that can be easily treated.

The causes of pyogenic granuloma are not well understood, but it is believed to be triggered by a variety of factors, including injury to the skin, hormonal changes, and certain medications. The lesion is most commonly found on the face, neck, and hands, and it can grow quickly, reaching a size of several centimeters within a few weeks.


Pyogenic granuloma is a type of benign skin lesion that often appears as a raised, red bump on the skin. There are several potential causes of this condition, including:

  1. Trauma or injury: Injuries to the skin, such as cuts, scrapes, or puncture wounds, can trigger the formation of a pyogenic granuloma.
  2. Hormonal changes: Hormonal fluctuations, particularly during pregnancy, can cause an increase in blood flow to the skin and increase the risk of pyogenic granulomas.
  3. Exposure to irritants: Exposure to certain irritants, such as chemicals or plant irritants, can cause skin reactions that lead to pyogenic granulomas.
  4. Infections: Certain infections, such as human papillomavirus (HPV) or staphylococcus, can cause pyogenic granulomas.
  5. Medical conditions: Certain medical conditions, such as autoimmune disorders or certain medications, can increase the risk of developing pyogenic granulomas.

It is important to note that the exact cause of pyogenic granulomas is not always clear, and in many cases, the lesion may form without any obvious triggering factor. If you suspect you have a pyogenic granuloma, it is important to consult a dermatologist for proper diagnosis and treatment.


Pyogenic granuloma is a benign (non-cancerous) skin lesion that appears as a red, elevated, and often painful bump. The main symptoms of pyogenic granuloma are:

  1. Elevated bump: The bump is usually round or oval in shape and can range from a few millimeters to several centimeters in size.
  2. Red color: The bump is usually bright red in color and may be covered with small blood vessels that are visible to the naked eye.
  3. Painful: Pyogenic granulomas can be painful, especially when they are touched or bumped.
  4. Bleeding: The bump may bleed easily if it is bumped or scratched.
  5. Rapid growth: Pyogenic granulomas can grow rapidly, sometimes doubling in size within a few days.
  6. Location: Pyogenic granulomas can occur anywhere on the body, but are most commonly found on the face, neck, and arms.
  7. Itchy or irritated: Some people may experience itching or irritation in the area of the bump.

It is important to see a doctor if you suspect that you have a pyogenic granuloma, as it can be easily confused with other skin conditions. A biopsy may be necessary to confirm the diagnosis.


Diagnosis: The diagnosis of pyogenic granuloma is usually made based on its appearance. The doctor may examine the lesion and may also perform a biopsy to confirm the diagnosis. In a biopsy, a small sample of the lesion is taken and sent to a laboratory for analysis.

Tests: Some of the tests that may be performed to diagnose pyogenic granuloma include:

  1. Physical examination: The doctor will examine the lesion and may also ask questions about the patient’s medical history to determine the cause of the lesion.
  2. Imaging studies: In some cases, the doctor may order imaging studies such as X-rays or MRI to determine if there is any underlying condition causing the pyogenic granuloma.
  3. Biopsy: A biopsy is the most important diagnostic test for pyogenic granuloma. During this procedure, a small sample of the lesion is removed and sent for pathological examination to confirm the diagnosis.
  4. Dermoscopy: Dermoscopy is a non-invasive diagnostic tool that uses a special magnifying lens to examine the skin lesion in detail. This test can help to differentiate pyogenic granuloma from other similar-looking skin conditions.
  5. X-ray: If the lesion is large or located in an inaccessible area, imaging studies such as X-rays, CT scans, or MRI scans may be used to determine the extent of the lesion.

In conclusion, the pyogenic granuloma is usually diagnosed based on its appearance and a biopsy may be performed to confirm the diagnosis. Other tests such as dermoscopy and imaging studies may also be performed to determine the cause of the lesion.


Although it is called pyogenic (pus-producing), it is not actually an infected lesion.

The main treatments for pyogenic granuloma include:

  1. Surgical excision: This is the most common and effective treatment for pyogenic granuloma. The lesion is cut out using a scalpel and the surrounding tissue is then stitched together. This procedure is usually done under local anesthesia.
  2. Electrocautery: This procedure involves using a hot wire to destroy the cells. It is often used for larger or more widespread lesions.
  3. Topical medications: Topical medications such as imiquimod (Aldara) or 5-fluorouracil (Efudex) can be applied to the lesion to destroy the cells. This treatment is typically used for small or superficial lesions.
  4. Surgical excision: This is the most common treatment for pyogenic granuloma and involves removing the growth using a scalpel or other surgical instrument. The wound is then closed with stitches or staples.
  5. Cryotherapy: This treatment involves freezing the growth with liquid nitrogen, which causes it to die and eventually fall off. This is a less invasive option for people with smaller growths.
  6. Electrocautery: This treatment uses electrical current to destroy growth. This is a quick and effective option for people with larger growths.
  7. Laser therapy: This treatment uses laser energy to destroy the growth and is often used for people with multiple growths or those who have had previous treatments that did not work.

The choice of treatment depends on the size and location of the lesion, as well as the patient’s individual needs and preferences. In some cases, the lesion may resolve on its own without any treatment.