Persistent Hypoglossal Artery Disorders

Persistent hypoglossal artery (PHA) disorders are rare vascular anomalies that can affect the blood vessels around the base of the brain. Understanding these disorders involves exploring their types, causes, symptoms, diagnosis, treatments, and preventive measures.

Types of Persistent Hypoglossal Artery Disorders

Persistent hypoglossal artery disorders can manifest in different forms:

  1. Persistent Hypoglossal Artery (PHA)
    • The persistent presence of the embryonic hypoglossal artery, which normally regresses during fetal development.
  2. Persistent Hypoglossal Artery with Aneurysm
    • When the persistent artery forms an aneurysm, potentially leading to complications.

Causes of Persistent Hypoglossal Artery Disorders

The exact causes of PHA disorders aren’t fully understood, but several factors may contribute:

  • Embryological Development: Anomalies during fetal development where the hypoglossal artery fails to regress.
  • Genetic Factors: Possible genetic predispositions leading to vascular abnormalities.
  • Environmental Influences: Certain environmental factors might play a role, though research is ongoing.

Symptoms of Persistent Hypoglossal Artery Disorders

Symptoms can vary depending on the specific disorder and its complications:

  • Neurological Symptoms: Such as headaches, dizziness, or neurological deficits.
  • Aneurysm-related Symptoms: Including sudden severe headache, vision problems, or neurological changes.

Diagnostic Tests for Persistent Hypoglossal Artery Disorders

Diagnosing PHA disorders often involves several tests:

  1. Imaging Tests:
    • MRI (Magnetic Resonance Imaging): Provides detailed images of the brain and blood vessels.
    • CT Angiography (Computed Tomography Angiography): Uses contrast dye to visualize blood vessels.
  2. Cerebral Angiography: Involves injecting contrast dye into blood vessels to observe blood flow in the brain.

Non-Pharmacological Treatments for Persistent Hypoglossal Artery Disorders

Treatment approaches focus on managing symptoms and preventing complications:

  1. Observation: Monitoring the condition over time with regular imaging tests.
  2. Endovascular Therapy: Minimally invasive procedures to treat aneurysms or abnormal blood vessels.
  3. Surgical Interventions: In cases where the risk of complications is high, surgical removal of aneurysms or abnormal vessels may be necessary.

Medications for Persistent Hypoglossal Artery Disorders

Specific drugs may be prescribed to manage symptoms or prevent complications:

  • Antiplatelet Medications: To reduce the risk of blood clots.
  • Pain Management: Medications to alleviate headaches or other symptoms.

Surgeries for Persistent Hypoglossal Artery Disorders

Surgical options depend on the specific condition and its severity:

  • Aneurysm Clipping: Surgically clipping off an aneurysm to prevent rupture.
  • Endovascular Coiling: Inserting coils into an aneurysm to block blood flow and prevent rupture.

Preventive Measures for Persistent Hypoglossal Artery Disorders

While prevention strategies are limited due to the developmental nature of PHA disorders:

  • Early Detection: Regular check-ups and imaging for individuals at risk or showing symptoms.
  • Healthy Lifestyle: Managing blood pressure and avoiding smoking may reduce risks associated with vascular conditions.

When to See a Doctor

It’s important to seek medical attention if you experience:

  • Sudden Severe Headaches: Especially if accompanied by neurological changes.
  • Vision Problems: Sudden changes in vision or difficulty with eye movements.
  • Neurological Deficits: Weakness, numbness, or speech difficulties.

 

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.

  1. https://www.ncbi.nlm.nih.gov/books/NBK532297/
  2. https://www.ncbi.nlm.nih.gov/books/NBK549894/
  3. https://pubmed.ncbi.nlm.nih.gov/32119229/
  4. https://pubmed.ncbi.nlm.nih.gov/2644925/
  5. https://pubmed.ncbi.nlm.nih.gov/19514525/
  6. https://pubmed.ncbi.nlm.nih.gov/37988502/
  7. https://www.ncbi.nlm.nih.gov/books/NBK361950/
  8. https://www.ncbi.nlm.nih.gov/books/NBK223475/
  9. https://pubmed.ncbi.nlm.nih.gov/27227247/
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117533/
  11. https://pubmed.ncbi.nlm.nih.gov/32951666/
  12. https://www.ncbi.nlm.nih.gov/books/NBK20369/
  13. https://www.ncbi.nlm.nih.gov/books/NBK597504/
  14. https://medlineplus.gov/skinconditions.html
  15. https://www.aad.org/about/burden-of-skin-disease
  16. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  17. https://www.cdc.gov/niosh/topics/skin/default.html
  18. https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084
  19. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Understanding-Sleep
  20. https://www.cdc.gov/traumaticbraininjury/index.html
  21. https://www.skincancer.org/
  22. https://illnesshacker.com/
  23. https://endinglines.com/
  24. https://www.jaad.org/
  25. https://www.psoriasis.org/about-psoriasis/
  26. https://books.google.com/books?
  27. https://www.niams.nih.gov/health-topics/skin-diseases
  28. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  29. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
  30. https://dermnetnz.org/topics
  31. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  32. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
  33. https://aafa.org/allergies/allergy-symptoms/skin-allergies/
  34. https://www.nibib.nih.gov/
  35. https://rxharun.com/rxharun/rxharun/article-types/skin-care-beauty/skin-diseases-types-symptoms-treatment/
  36. https://www.nei.nih.gov/
  37. https://en.wikipedia.org/wiki/List_of_skin_conditions
  38. https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
  39. https://en.wikipedia.org/wiki/Skin_condition
  40. https://oxfordtreatment.com/
  41. https://www.nidcd.nih.gov/health/
  42. https://consumer.ftc.gov/articles/w
  43. https://www.nccih.nih.gov/health
  44. https://catalog.ninds.nih.gov/
  45. https://www.aarda.org/diseaselist/
  46. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
  47. https://www.nibib.nih.gov/
  48. https://www.nia.nih.gov/health/topics
  49. https://www.nichd.nih.gov/
  50. https://www.nimh.nih.gov/health/topics
  51. https://www.nichd.nih.gov/
  52. https://www.niehs.nih.gov
  53. https://www.nimhd.nih.gov/
  54. https://www.nhlbi.nih.gov/health-topics
  55. https://obssr.od.nih.gov/
  56. https://www.nichd.nih.gov/health/topics
  57. https://rarediseases.info.nih.gov/diseases
  58. https://beta.rarediseases.info.nih.gov/diseases
  59. https://orwh.od.nih.gov/

References