What Is Dermatomyositis 

Dermatomyositis is an autoimmune muscle disease that involves inflammation and a skin rash. It is a type of inflammatory myopathy. The cause of dermatomyositis is unknown. Experts think it may be due to a viral infection of the muscles or a problem with the body’s immune system. It may also occur in patients who have cancer in the abdomen, lung, or other parts of the body. Anyone can develop dermatomyositis. It most commonly occurs in children age 5 – 15 and adults age 40 – 60. Women develop this condition more often than men. Symptoms may include: problems swallowing, muscle weakness, stiffness, or soreness, purple color to the upper eyelids, purple-red skin rash, and shortness of breath. The muscle weakness may come on suddenly or develop slowly over weeks or months. You may have trouble raising your arms over your head, getting up from a sitting position, and climbing stairs. The rash may appear on your face, knuckles, neck, shoulders, upper chest, and back. Symptoms may go away completely in some people, such as children. The condition may be fatal in adults due to severe muscle weakness, malnutrition, pneumonia, or lung failure. The major causes of death with this condition are cancer and lung disease.[rx]

Types of Dermatomyositis:

  1. Classic Dermatomyositis: This is the most common type, characterized by muscle and skin involvement.

Causes of Dermatomyositis:

  1. Autoimmune Reaction: Dermatomyositis occurs when the immune system mistakenly attacks healthy skin and muscle tissues.
  2. Genetic Factors: Some individuals may have a genetic predisposition to the disease.
  3. Environmental Triggers: Infections or exposure to certain chemicals may trigger dermatomyositis in some cases.

Symptoms of Dermatomyositis:

  1. Muscle Weakness: You may experience difficulty in moving your muscles, making it hard to perform everyday tasks.
  2. Skin Rash: A distinctive skin rash often appears, most commonly on the face, knuckles, elbows, knees, or chest.
  3. Fatigue: Persistent tiredness is a common symptom of dermatomyositis.
  4. Difficulty Swallowing: Swallowing problems can occur due to muscle weakness.
  5. Joint Pain: Joint pain and stiffness may be present.

Diagnostic Tests for Dermatomyositis:

  1. Blood Tests: Doctors can check for specific antibodies in your blood that are associated with dermatomyositis.
  2. Muscle Biopsy: A small sample of muscle tissue is taken for examination to confirm the disease.
  3. Electromyography (EMG): This test measures electrical activity in your muscles and helps assess muscle damage.
  4. MRI and CT Scans: Imaging tests can show muscle inflammation and damage.
  5. Skin Biopsy: If you have skin symptoms, a skin biopsy may be done to examine tissue under a microscope.

Treatments for Dermatomyositis:

  1. Corticosteroids: These are powerful anti-inflammatory drugs used to reduce muscle and skin inflammation.
  2. Immunosuppressive Medications: Drugs like methotrexate or azathioprine can help control the immune system’s response.
  3. Physical Therapy: Exercise programs can improve muscle strength and flexibility.
  4. Occupational Therapy: This helps you adapt to daily activities despite muscle weakness.
  5. Sun Protection: Avoiding sun exposure and using sunscreen can protect sensitive skin.

Medications for Dermatomyositis:

  1. Prednisone: A common corticosteroid used to reduce inflammation.
  2. Methotrexate: An immunosuppressant that can help control the autoimmune response.
  3. Azathioprine: Another immunosuppressive drug used to manage the disease.
  4. Hydroxychloroquine: Often prescribed for skin symptoms.
  5. Mycophenolate Mofetil: An alternative immunosuppressive medication.
  6. Intravenous Immunoglobulin (IVIG): Used in severe cases to modulate the immune system.
  7. Topical Steroids: Creams or ointments to treat skin rashes.
  8. Calcium and Vitamin D Supplements: To support bone health while on medications.
  9. Pain Relievers: Over-the-counter or prescription pain medications for muscle and joint pain.
  10. Antimalarial Drugs: Sometimes used to treat skin symptoms.

In conclusion, dermatomyositis is a complex condition, but understanding its types, causes, symptoms, diagnostic tests, treatments, and medications can help simplify this challenging topic. If you suspect you have dermatomyositis, consult a healthcare professional for proper evaluation and guidance. Early diagnosis and appropriate treatment can make a significant difference in managing the condition and improving your quality of life.

 

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.

  1. https://medlineplus.gov/skinconditions.html
  2. https://www.aad.org/about/burden-of-skin-disease
  3. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  4. https://www.cdc.gov/niosh/topics/skin/default.html
  5. https://www.skincancer.org/
  6. https://illnesshacker.com/
  7. https://endinglines.com/
  8. https://www.jaad.org/
  9. https://www.psoriasis.org/about-psoriasis/
  10. https://books.google.com/books?
  11. https://www.niams.nih.gov/health-topics/skin-diseases
  12. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  13. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
  14. https://dermnetnz.org/topics
  15. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  16. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
  17. https://aafa.org/allergies/allergy-symptoms/skin-allergies/
  18. https://www.nibib.nih.gov/
  19. https://rxharun.com/rxharun/rxharun/article-types/skin-care-beauty/skin-diseases-types-symptoms-treatment/
  20. https://www.nei.nih.gov/
  21. https://en.wikipedia.org/wiki/List_of_skin_conditions
  22. https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
  23. https://en.wikipedia.org/wiki/Skin_condition
  24. https://oxfordtreatment.com/
  25. https://www.nidcd.nih.gov/health/
  26. https://consumer.ftc.gov/articles/w
  27. https://www.nccih.nih.gov/health
  28. https://catalog.ninds.nih.gov/
  29. https://www.aarda.org/diseaselist/
  30. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
  31. https://www.nibib.nih.gov/
  32. https://www.nia.nih.gov/health/topics
  33. https://www.nichd.nih.gov/
  34. https://www.nimh.nih.gov/health/topics
  35. https://www.nichd.nih.gov/
  36. https://www.niehs.nih.gov
  37. https://www.nimhd.nih.gov/
  38. https://www.nhlbi.nih.gov/health-topics
  39. https://obssr.od.nih.gov/
  40. https://www.nichd.nih.gov/health/topics
  41. https://rarediseases.info.nih.gov/diseases
  42. https://beta.rarediseases.info.nih.gov/diseases
  43. https://orwh.od.nih.gov/

References