An RBC count is a blood test that measures how many red blood cells (RBCs) you have.
RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.
How the Test is Performed
A blood sample is needed.
How to Prepare for the Test
No special preparation is necessary.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
The RBC count is almost always part of a complete blood count ( CBC ) test.
The test can help diagnose different kinds of anemia (low number of RBCs) and other conditions affecting red blood cells.
Other conditions that may require an RBC count are:
- Disease that damages kidney blood vessels ( Alport syndrome )
- White blood cell cancer ( Waldenstrom macroglobulinemia )
- Disorder in which red blood cells break down earlier than normal ( paroxysmal nocturnal hemoglobinuria )
- Bone marrow disorder in which the marrow is replaced by scar tissue (myelofibrosis)
Normal Results
Normal RBC ranges are:
- Male: 4.7 to 6.1 million cells per microliter (cells/mcL)
- Female: 4.2 to 5.4 million cells/mcL
The ranges above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your health care provider about the meaning of your specific test results.
What Abnormal Results Mean
Higher than normal numbers of RBCs may be due to:
- Cigarette smoking
- Problem with heart’s structure and function that is present at birth ( congenital heart disease )
- Failure of the right side of the heart ( cor pulmonale )
- Dehydration (for example, from severe diarrhea)
- Kidney tumor (renal cell carcinoma)
- Low blood oxygen level (hypoxia)
- Scarring or thickening of the lungs ( pulmonary fibrosis )
- Bone marrow disease that causes abnormal increase in RBCs ( polycythemia vera )
Your RBC count will increase for several weeks when you are in a higher altitude.
Drugs that can increase the RBC count include:
- Gentamicin
- Methyldopa
Lower-than-normal numbers of RBCs may be due to:
- Anemia
- Bleeding
- Bone marrow failure (for example, from radiation, toxins, or tumor)
- Deficiency of a hormone called erythropoietin (caused by kidney disease)
- RBC destruction ( hemolysis ) due to transfusion, blood vessel injury, or other cause
- Leukemia
- Malnutrition
- Bone marrow cancer called multiple myeloma
- Too little iron, copper , folic acid, vitamin B6 , or vitamin B12 in the diet
- Too much water in the body (overhydration)
- Pregnancy
Drugs that can decrease the RBC count include:
- Chemotherapy drugs
- Chloramphenicol
- Hydantoins
- Quinidine
Risks
There is very little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
- Excessive bleeding
- Fainting or feeling lightheaded
- Hematoma (blood buildup under the skin)
- Infection (a slight risk any time the skin is broken)
RBC indices
Erythrocyte indices; Blood indices; Mean corpuscular hemoglobin (MCH); Mean corpuscular hemoglobin concentration (MCHC); Mean corpuscular volume (MCV); Red blood cell indices
Red blood cell (RBC) indices are part of the complete blood count (CBC) test. They are used to help diagnose the cause of anemia, a condition in which there are too few red blood cells.
The indices include:
- Average red blood cell size (MCV)
- Hemoglobin amount per red blood cell (MCH)
- The amount of hemoglobin relative to the size of the cell (hemoglobin concentration) per red blood cell (MCHC)
How the Test is Performed
A blood sample is needed.
How to Prepare for the Test
No special preparation is necessary.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
Hemoglobin transports oxygen. RBCs carry hemoglobin and oxygen to our body’s cells. The RBC indices test measures how well the RBCs do this. The results are used to diagnose different types of anemia .
Normal Results
These test results are in the normal range:
- MCV: 80 to 100 femtoliter
- MCH: 27 to 31 picograms/cell
- MCHC: 32 to 36 grams/deciliter (g/dL) or 320 to 360 grams per liter (g/L)
The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your health care provider about the meaning of your specific test results.
What Abnormal Results Mean
These test results indicate the type of anemia:
- MCV below normal. Microcytic anemia (may be due to low iron levels, lead poisoning, or thalassemia ).
- MCV normal. Normocytic anemia (may be due to sudden blood loss, long-term diseases, kidney failure , aplastic anemia , or man-made heart valves).
- MCV above normal. Macrocytic anemia (may be due to low folate or B12 levels, or chemotherapy ).
- MCH below normal. Hypochromic anemia (often due to low iron levels).
- MCH normal. Normochromic anemia (may be due to sudden blood loss, long-term diseases, kidney failure, aplastic anemia, or man-made heart valves).
- MCH above normal. Hyperchromic anemia (may be due to low folate or B12 levels, or chemotherapy).
Risks
Veins and arteries vary in size from one person to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
- Excessive bleeding
- Fainting or feeling lightheaded
- Hematoma (blood buildup under the skin)
- Infection (a slight risk any time the skin is broken)
