Ampalaya/Bitter Gourd – Health Benefits, Dosage, Side Effects

Ampalaya/Bitter gourd, with the scientific name of Momordica charantia, is a tropical and subtropical vine. It is often grown in the Caribbean, the Amazon, and Southeast Asia. Because of its abundance in the Philippines and some surrounding countries, various savory recipes make the most of its signature bitter flavor. This comes from the Momordica in the vegetable.

Scientific Name: Momordica charantia

Other names

  • Ampalaya,

  • Bitter melon,

  • papailla,

  • melao de sao caetano,

  • bittergourd, sorosi, a’jayib al maasi,

  • assorossie,

  • balsam apple,

  • balsam pear,

  • chin li chih, ejinrin gule khandan, fu-kua, karela, k’u kua kurela,

  • kor-kuey, ku gua, lai p’u t’ao, pava-aki, salsamino, sorci, sorossi, sorossie, sorossies, pare, peria laut, peria

Ampalaya Bitter Melon (Momordica charantia) also known as Bitter Melon is a tropical and subtropical vine of the family Cucurbitaceae, widely grown in the Amazon, Caribbean, Southeast Asia such as the Philippines for its edible fruit. Ampalaya or bitter melon also known as bitter gourd as the name implies has a bitter taste due to the presence of Momordica and is believed to be among the most bitter of all vegetables.

Ampalaya Bitter Melon is a climbing vine that grows up to 5m, with tendrils up to 20cm. long. Ampalaya leaves are heart-shaped, 5-10 cm across, cut into 5-7 lobes. Each Ampalaya Bitter Melon plant bears separate yellow male and female flowers. Ampalaya bears fleshy green fruit, oblong-shaped with pointed ends, ribbed and wrinkled, bursting when mature to release seeds. Ampalaya seeds are flat with ruminated margins.

Nutrition Facts

Sources include: USDA

Amount Per 

Calories 34
% Daily Value*
Total Fat 0.2 g 0%
Saturated fat 0 g 0%
Cholesterol 0 mg 0%
Sodium 13 mg 0%
Potassium 602 mg 17%
Total Carbohydrate 7 g 2%
Dietary fiber 1.9 g 7%
Sugar 1 g
Protein 3.6 g 7%
Vitamin C 92% Calcium 4%
Iron 5% Vitamin D 0%
Vitamin B6 40% Cobalamin 0%
Magnesium 23%
* percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

Ampalaya Traditional Medicinal Uses and Health benefits

Ampalaya has a long history of medical usage and has a long list of folkloric health benefits for the following conditions.

  • Diabetes. Ampalaya or bitter gourd is a widely used herbal remedy to lower blood sugar levels for diabetic patients.
  • Analgesic. The juice of Ampalaya is used to alleviate symptoms of fever, headache, and body pains.
  • Eye problems. Ampalaya juice is also used to treat eye-related problems that include sty and sore eyes. It is thought to improve eyesight and prevents the development of cataract.
  • Respiratory ailments. The juice from ampalaya fruit and leaves is used to treat various respiratory problems that may include, asthma, wheezing cough, bronchitis, and pharyngitis.
  • Hair and scalp problems. Ampalaya or bitter gourd has been used to treat various hair and scalp problems that may include hair loss, dry scalp, lice, and pimples on the scalp.
  • Weight loss. Ampalaya is also used to promote body metabolism and the burning of fats thus it is valued as a weight loss supplement.
  • Source of energy. The vitamins and mineral found in ampalaya is considered as a stamina builder that combats fatigue.
  • Antioxidant. Ampalaya is also considered as a potent antioxidant activity that counters the oxidation of free radicals that is the cause of cancer.
  • Stomach problems. Ampalaya leaf extract is a folkloric remedy for various stomach aches and problems that include indigestion, dyspepsia, parasite infestation, diarrhea, and constipation.
  • Hepatoprotection activity. Ampalaya is used as a herbal remedy to protect the liver from damage due to the intake of alcohol and other harmful substances.
  • Skin problems. Ampalaya is crushed or rubbed over the skin to alleviate symptoms of psoriasis, ringworm, athlete’s foot, wounds, burns, and ulcers.
  • Boosts the immune system.  Ampalaya is also used to boost the immune system and as a supplement to build body resistance during sickness.
  • HIV virus. Ampalaya is also being considered as a treatment to viral diseases that include HIV, malaria, chicken fox and measles.
  • Menopause. Ampalaya tea is taken as a remedy for pain and discomfort associated to menopause.
  • Anti-inflammatory activity. Ampalaya leaf extract combined with coconut oil is used to alleviate inflammation and pain associated with gout, arthritis, rheumatism, and other body pains.
  • Cholesterol control. Ampalaya is also widely consumed to lower the cholesterol level in the blood that helps to prevent the build-up of plaque along the arterial walls.
  • Hemorrhoids. Ampalaya is used as an astringent to treat hemorrhoids.
  • Contraceptive. Ampalaya has been used in folkloric medicine as an abortifacient and as a contraceptive to prevent pregnancy.

Ginisang Ampalaya Recipes

  •  Prep Time10 minutes
  • Cook Time20 minutes
  • Total Time30 minutes

Ingredients

  • 2 pieces ampalaya cleaned and cut into thin slices
  • 1 tbsp garlic minced
  • 1/2 tsp ground black pepper
  • salt to taste
  • 2 raw eggs
  • 18 ounces luke warm water
  • 1 large tomato sliced
  • 1 large onion sliced
  • 3 tbsp cooking oil

Instructions

  • Place the ampalaya in a large bowl
  • Add salt and lukewarm water then leave for 5 minutes
  • Place the ampalaya in a cheesecloth then squeeze tightly until all liquid drips
  • Heat the pan and place the cooking oil
  • Saute the garlic, onion, and tomato
  • Add the ampalaya mix well with the other ingredients
  • Put-in salt and pepper to taste
  • Beat the eggs and pour over the ampalaya then let the eggs cook partially
  • Mix the egg with the other ingredients
  • Serve hot. Share and Enjoy!

Nutrition

Serving: 4g

How to cook with ampalaya and get rid of some of its bitterness:

Making use of the bitter melon evidently involves some preparation beforehand. You can start by slicing it open vertically along the length. Then take a spoon, and scrape out all of the sides, as well as the white pith. This white is where you could taste most of the acridity. And so take it out as much as you can. What you will essentially be left with is the green gourd you’ll be needing for most dishes. Majority of the time, the preferred size is in ¼-inch pieces that are shaped like a half moon. Try to slice it in this manner.

The next part is a step that could heavily improve your dish, depending on your preference of bitterness. But if you’d like a much milder sense of acridity, one way to remove some bitterness is by rubbing 1 teaspoon of salt inside the ampalaya. Make sure to apply this step to both halves of your bitter melon, then wait for 5 minutes. Then you might be able to see some moisture, and that the bitter sap has exited from your ampalaya.

bitter gourd ampalaya

Other techniques to lessen acridity:

There are other steps you could adopt for a similar effect. You could do well by slicing up your ampalaya in pieces in the half moon shape for your starting step. Then put them in a bowl. Rinse this well with water, then dry your sliced bitter gourd. This easy step could still remove plenty of what could be an unpleasant flavor to some.

Another option also utilizes the rinsing method, but with some more time in the bowl of water. Try this with salted, lukewarm water to contrast the ampalaya’s acridity. Take note that more time soaking the vegetable would mean less of its natural bitter flavor. With this, you can soak this from a minimum of 5 minutes to overnight. Then you are likely to wake up with only some mild bitterness left to your ampalaya.

Another tip to make sure that the ampalaya does not end up too bitter is by ensuring that you cook it just the right amount. Spending too much time above heat and a stove could bring out even more of the bitterness you might be avoiding for the ampalaya. Keep a watchful eye while cooking your rich, flavorful bitter gourd.

Choosing and storing your bitter gourd:

Another factor you should look at to ensure less of a bitter ampalaya is its ripeness. If it is unripe, it tends to be less bitter, and it is bright green and firm. When you stroll around the markets looking for your supply of bitter melon, keep an eye out for these kinds of ampalaya. This is because milder bitterness is ideal for most dishes. And on the other hand, you probably should try to keep away from bitter gourd that leans towards a more orange or red shade. This indicates a more ripe ampalaya with more bitterness.

Now if you want to keep your ampalaya from ripening, you can keep it in the fridge for approximately 4 days. This can slow down the ripening process, while keeping your vegetable from rotting.

It might seem like a bit much to be preparing this vegetable. This is especially given how it can usually be an unideal amount of bitter to the taste. But a little patience in cooking this nutritious ingredient could lead to a great deal of health benefits in the future!

Health benefits that come with eating ampalaya:

Filipinos have mixed this vegetable with a great amount of dishes, and this should come as no surprise. Because of the abundance of vegetables grown all over the country, it is a fairly accessible and low-cost way to boost your health. Ampalaya has 22 percent of the average daily requirement for folate or folic acid in its synthetic form. With this, the Harvard School of Public Health has said that increasing your intake of the bitter gourd can help prevent breast cancer, colon cancer and strokes.

ampalaya vegetable

But the advantages of incorporating this ingredient in your diet don’t stop here. It is also rich in dietary fiber. This means it could be beneficial in maintaining your gastrointestinal health, while protecting you from diabetes and heart disease.

And a lesser known fact about ampalaya is that one piece of this winkly vegetable is said to have 174 percent of the average daily requirement for Vitamin C. And Vitamin C, a great antioxidant, can help you make great strides towards protecting your cells from harmful free radicals.

Of course, if you are looking to improve your eating habits in consuming less calories, ampalaya also makes for a fantastic, piquant option. It has a lower amount of calories than most other ingredients. And this is while retaining some of the most helpful vitamins and nutrients. Other than folate and Vitamin C, the bitter melon also contains Vitamins B1, B2, and B3. Moreover, it is rich in manganese, phosphorus, zinc and iron. As such, iron can aid your body’s process of making more hemoglobin, which is great for your blood health.

Its health benefits compared to other food:

Ampalaya is also able to more than hold itself with pride when compared to other healthy food options. For one, it has twice the amount of potassium that bananas have. Following suit to this health benefit, broccoli only has about half the beta-carotene there is in the bitter gourd. It also has double the calcium that spinach has, meaning it will be largely advantageous for your bone health.

bitter ampalaya

And if all of these benefits have you convinced, you might be thinking of one thing. What can I make of this crumpled, strongly flavored and sustaining ingredient? Well, the good news is that you have a plethora of options to choose from. Despite the sometimes overpowering strength of the ampalaya’s bitterness, it actually tastes exquisitely good with various kinds of meat. And its unique acridity also makes it a gorgeous match for most mild ingredients or fellow vegetables.

Interested in figuring out a few recipes to try out with ampalaya? Here’s a list of some of my favorite dishes to have with the deliciously vinegary bitter gourd.

Recipes with ampalaya to try in your own kitchen:

Ginisang Ampalaya (Sauteéd Bitter Melon)
As mentioned earlier, the ampalaya is significantly known for one thing– it’s one of a kind, and easily recognizable sharp taste. But the bitterness, when utilized properly, is something you can make some of the best, most flavor-packed dishes with!

Ginisang Ampalaya is easily one of the best Filipino classics when it comes to savory dishes that take little time, but hold an abundance of flavor and healthy components. This recipe makes the most of tomatoes, onions, eggs and ampalaya. And this is to create a dish that mimics some of the distinct salty flavors of a regular meat recipe. And yet, it has all the magic and health benefits of a meal brimming with vegetables. But if you prefer a bit less acridity in your Ginisang Ampalaya, you could also try the methods written above. And in result, you could enjoy this dish with more of the other ingredients’ flavors shining through the bitterness.

Ginisang Ampalaya with Shrimp (Sauteéd Bitter Gourd)
There is an ease that comes with working with vegetables. This is partially because of their share of nutrients, as well as the distinctly striking textures they bring to a dish. But this texture could do well with some of the unique flavors brought by seafood ingredients. And flavors from the sea tend to be milder than meat. This could go well with what else but the rich ampalaya.

This Ginisang Ampalaya with shrimp essentially uses the same easy and clear steps as the recipe before this one. That is why it only takes a mere 35 minutes to make. But it also has the soft and salty taste of carefully sautéed shrimp. While this recipe is plenty flavorful and delightful on its own, its taste can be elevated further. It is best to try it with some fish sauce and spicy chili. Mix and match your own spices and seasonings with this dish, as it adapts well with other flavors too!

ampalaya vegetable healthy

Ampalaya Salad

Otherwise known as ensaladang ampalaya, this Ampalaya salad is a simple recipe for when all you’re looking for is a good, clean mix of fresh vegetables and the most piquant seasonings. Chopped up red onions and bright green bitter melon come together to make a vibrant salad dish you can easily whip up at home. The trick to making the most of this recipe and its crispy, juicy textures is by cutting your onions and ampalaya thinly. Of course, it would also help to ease your level of acridity a bit. You can do this by rubbing some salt onto your bitter melon. This would help it go even better with your combination of Roma tomatoes, vinegar and black pepper. Give yourself a light side dish or snack with this nutritious, colorful salad!

Beef in Oyster Sauce Stir Fry with Ampalaya

Playing with your flavors in a dish could create some delectable results. This is why spices and seasonings can truly make the mark of a recipe. As such, my Beef in Oyster Sauce Stir Fry with Ampalaya utilizes various flavors. This can range from sesame oil and sherry cooking wine to soy sauce to contrast our bitter gourd’s natural acridity. Oyster sauce, in its mild sweetness and unique saltiness, particularly plays well with the ampalaya not only flavor-wise, but also with regards to texture.

Coating our bitter gourd in the deliciously savory oyster sauce gives it a one of a kind flavor that also has a harmonious relationship with tender strips of tasty beef sirloin. I would also suggest grabbing your Worcestershire sauce if you’ve got a bottle of your own when eating away at this dish. It is yet another seasoning that integrates well into the dish, especially with a cup of warm white rice.

Ampalaya con Carne

Getting a single whiff of this dish while it’s cooking in the kitchen will tell you all you need to know about this Ampalaya con Carne. Sautéed in garlic, ginger and onion, your mix of marinated beef and ampalaya come together for an irresistible savory dish. This also conveniently only takes about 20 minutes to make with a simple recipe of quite accessible ingredients. But diners of this delicious dish may be oblivious to the easy preparation of this dish what with the rich flavors that will come in this bowl of fragrant beef sirloin and ampalaya. Similar to the previous recipe, which also utilizes beef, this Con Carne would taste especially pleasant with some rice to complement its powerful flavor and rich, tasty stew.

Stuffed Ampalaya

Wrapped all over excluding the top by a crinkled, green coat of ampalaya, and oozing in appetizing, salty flavor brought by a wealth of black pepper and paprika– you can do even more with your ground pork by taking on this Stuffed Ampalaya recipe! There is something especially tasty about meat stuffed in deliciously crunchy casing, and this utilizes that very technique. Resembling embutido and its unique, salty-sweet flavor with a little less of the sweetness and more of our signature bitterness, this dish makes use of a delicious ground pork mixture to collaborate well with the acridity of bitter gourd. You’ll come out of the kitchen with some wonderfully colored stuffed bitter melon with golden brown pork peeking from the top. And this recipe is great for 4 people, so it would be great to share with family or friends!

Kalabasa Soup with Ampalaya Leaves

The first thing that probably comes to mind at the mention of ampalaya is the classic bitter melon that graces many a delicious Filipino dish. But another significantly tasty ingredient brought by the subtropical vine the vegetable comes from are the tiny, heart-shaped leaves. And instead of the body of the bitter gourd, this recipe makes use of nutritious ampalaya leaves. But this ingredient isn’t solely remarkable for all the good it can bring to your health. It also adds a component with softer texture and great flavor to your traditional kalabasa or pumpkin soup. And with a very minimum amount of ingredients ranging from savory chicken broth to salty garlic powder, you can make a colorful, delectable dish.

Try this recipe for some simple steps towards a comforting bowl of warm kalabasa and tender ampalaya leaves.
While the general consensus towards ampalaya may generally be towards the avoidant side, there’s no harm in trying it with a couple of new recipes! And if the issue lies on the excessive bitterness of the vegetable, you can try some of the techniques listed above to alleviate that. With all of the delectable, not to mention healthy, dishes in the bitter gourd’s arsenal, perhaps it’s time to start getting more of it for your kitchen.

Science Research: Momordica charantia Health Benefits

Antioxidant properties of Momordica Charantia (bitter gourd) seeds on Streptozotocin-induced diabetic rats.
The aim of the present study is to investigate the antioxidant activities of the aqueous extract of seeds of Momordica charantia in streptozotocin-induced diabetic rats. Oral administration of seed extracts at a concentration of 150 mg/kg b.w for 30 days showed a significant decrease in fasting blood glucose, hepatic and renal thiobarbituric acid reactive substances, and hydroperoxides. The treatment also resulted in a significant increase in reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase, and glutathione-s-transferase in the liver and kidney of diabetic rats. The results clearly suggest that seeds of the Momordica charantia treated group may effectively normalize the impaired antioxidant status in streptozotocin induced-diabetes than the glibenclamide treated groups. The extract exerted rapid protective effects against lipid peroxidation by scavenging of free radicals thereby reducing the risk of diabetic complications. Source : Asia Pacific Journal of Clinical Nutrition 2015.
https://www.ncbi.nlm.nih.gov/pubmed/15927932

Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis.
In this study, we have used human breast cancer cells, and primary human mammary epithelial cells as an in vitro model to assess the efficacy of bitter melon (Momordica charantia) extract as an anticancer agent. The bitter melon (Momordica charantia) extract treatment of breast cancer cells resulted in a significant decrease in cell proliferation and induced apoptotic cell death. Subsequent studies showed that bitter melon extract treatment of breast cancer cells inhibited survivin and claspin expression. Further studies revealed that bitter melon extract treatment enhanced p53, p21, and pChk1/2 and inhibited cyclin B1 and cyclin D1 expression, suggesting an additional mechanism involving cell cycle regulation. Together, these results show that bitter melon extract modulates signal transduction pathways for inhibition of breast cancer cell growth and can be used as a dietary supplement for the prevention of breast cancer. Source: Cancer Research March 2010
https://www.ncbi.nlm.nih.gov/pubmed/20179194

Momordica charantia for type 2 diabetes mellitus.
Momordica charantia (bitter gourd) is not only a nutritious vegetable but it is also used in traditional medical practices to treat type 2 diabetes mellitus. Experimental studies with animals and humans suggested that the vegetable has a possible role in glycaemic control. The study assessed the effects of Momordica charantia for type 2 diabetes mellitus. Source:  Cochrane Database Syst Rev. 2012 Aug
https://www.ncbi.nlm.nih.gov/pubmed/22895968

Momordica charantia and type 2 diabetes: from in vitro to human studies.
This review describes the anti-diabetic effects of bitter gourd reported in the literature and discusses what still needs to be clarified for developing an evidence-based and safe use of the bitter gourd for diabetes. Analyses of bioactive compounds have shown that bitter gourd is rich in nutrients and phytochemicals of which some have anti-diabetic effects. Juices, powders, extracts, and isolated compounds have been tested in vitro and in vivo. Bitter gourd increases insulin secretion of the pancreas, decreases intestinal glucose uptake, and increases uptake and utilization of glucose in peripheral tissues. Although human studies with type 2 diabetics are weak in their design and/or results, some of the studies do indicate anti-diabetic effects in patients and safety for bitter gourd treatment in humans. In the future, well designed studies with rodents will help to understand what kind of bitter gourd variety, dosage, preparation, and duration of administration is optimal. Such results will help to design human studies which are necessary to prove the effectiveness of bitter gourd in patients. Source: Current Diabetes Reviews. 2014 Jan.
https://www.ncbi.nlm.nih.gov/pubmed/24295371

Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways.
The study evaluated and explored the potential effectiveness of Momordica charanti. , Methanol extract of Momordica charantia was used to evaluate the cytotoxic activity on four human cancer cell lines,  in this study. Methanol extract of Momordica charantia showed cytotoxic activity towards all cancer cells tested, with the approximate IC(50) ranging from 0.25 to 0.35 mg/mL at 24 h. MCME induced cell death was found to be time-dependent in these cells. Methanol extract of Momordica charantia activated caspase-3 and enhanced the cleavage of downstream DFF45 and PARP, subsequently leading to DNA fragmentation and nuclear condensation. The apoptogenic protein, Bax, was increased, whereas Bcl-2 was decreased after treating for 24 h in all cancer cells, indicating the involvement of mitochondrial pathway in MCME-induced cell death. These findings indicate that CME has cytotoxic effects on human cancer cells and exhibits promising anti-cancer activity by triggering apoptosis through the regulation of caspases and mitochondria. Source: Evidence Based Complementary and Alternative Medicine 2012.
https://www.ncbi.nlm.nih.gov/pubmed/23091557

Influence of Momordica charantia on oxidative stress-induced perturbations in brain monoamines and plasma corticosterone in albino rats
The objective of this study was to evaluate the antistress activity of Momordica charantia  fruit extract on stress-induced changes in albino rats and also to explore attenuating effects of MC on in vitro lipid peroxidation in rat brain. Results have showed that pretreatment with MC at doses of 200 and 400 mg/kg p.o. significantly countered AS-induced changes and a similar effect was exhibited by PQ at 100 mg/kg p.o.  This study reveals the antistress activity of MC as it significantly reverted the stress-induced changes, and the activity might be attributed to its antioxidant activity since stress is known to involve several oxidative mechanisms. Source: Indian Pharmacological Society. 2011 Jul-Aug
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153706/

How to Get and How to Use Ampalaya

Where can I get or buy Ampalaya?

Ampalaya or Bitter Melon for Cooking. Ampalaya fruits and leaves are usually available in Asian or Chinese markets. They can be bought fresh by kilo, per piece or by bundles.

Ampalaya or Bitter Melon Capsules, Bitter melon, as its name implies, is quite bitter, which is why many often prefer to take capsules and tablets. Ready-made bitter melon extracts are available in capsules and tablets in many Asian markets, herb shops, and in the supplement department of health food stores.

The internet is full of online stores that sells ampalaya extracts, tablets or capsules, When you do, look for standardized extracts (to 10% charantin for instance) or concentrated whole fruit extracts (4:1 or 5:1) to help insure sufficient activity. If you are in US, Canada or UK, where Asian or Chinese health shops may not be available. Amazon.com provides an alternative. Look for products that have favorable customers reviews such as Bitter Melon GOLD. We are not affiliated with this brand and give this only as a sample reference. There are numerous to pick from, but be sure to review the manufacturer and the comments to ensure quality and safety.

How to Use Ampalaya Herbal Medicine

Cooking. Green fruit and young leaves of Ampalaya are cooked mixed with meat. To lessen the bitterness of the ampalaya fruit, wash or even boiled in water with salt.

Poultice. Grounded ampalaya leaves, seeds and root are prepared as poultice applied externally over the affected area to alleviate pain and symptoms of inflammation. It is usually mixed with other herbal oils such as olive and coconut oil.

Ampalaya herbal tea. Decoction of tea may be prepared from the powdered Ampalaya or Bitter Melon leaves, seeds and flower.

Ampalaya herbal tea or decoction

  1. Cut or crush a cup of Ampalaya seeds, leaves and flowers
  2. Steep in 4 cups of boiling water for 10 to 15 minutes
  3. Let it cool and strain
  4. drink a cup three times a day.

Ampalaya herbal tea is good to last for one day. Make new Ampalaya herbal tea as needed.

Dried ampalaya leaves, flowers and seeds are more potent, use at half dosage.

Ampalaya or Bitter Melon Juice. Ampalaya Bitter melon leaves and fruit (without the seeds) are pounded and juiced to extract concentrated juice. The juice can be taken at a spoonful for adults while teaspoonful for children. Ampalaya bitter melon juice can also be added to other pleasant tasting juice for drinking. Dosage is 1 tablespoon 2 times a day until symptoms improve.

Dosage, Warnings, and Side Effects of Ampalaya

Ampalaya fruit and young leaves are considered safe for consumption as found in food. Herbal medicine preparations should be taken as recommended for most adults. Just like any other herbal medicine, the key is moderation of use.

Counter indications:

When under medications for diabetes, hypertension, heart problems, etc., Taking Ampalaya in medicinal dosages may counter-act or aggravate its effectiveness. It is advised to consult your doctor before using this herb.

Pregnancy and Breastfeeding. There is a study that suggests the abortive action of Momordica charantia in large doses during pregnancy. It is recommended to avoid its use more than what is found in food.