Cause of Eye Diseases
The most common causes of visual impairment globally in 2010 were:
- Refractive error (42%)
- cataract (33%)
- glaucoma (2%)
- age related macular degeneration (1%)
- corneal opacification (1%)
- diabetic retinopathy (1%)
- childhood blindness
- trachoma (1%)
- undetermined (18%)
The most common causes of blindness in 2010 were
- cataracts (51%)
- glaucoma (8%)
- age related macular degeneration (5%)
- corneal opacification (4%)
- childhood blindness (4%)
- refractive errors (3%)
- trachoma (3%)
- diabetic retinopathy (1%)
- undetermined (21%)
About 90% of people who are visually impaired live in the developing world. Age-related macular degeneration, glaucoma, and diabetic retinopathy are the leading causes of blindness in the developed world.
Among working age adults who are newly blind in England and Wales the most common causes in 2010 were
- Hereditary retinal disorders (20.2%)
- Diabetic retinopathy (14.4%)
- Optic atrophy (14.1%)
- Glaucoma (5.9%)
- Congenital abnormalities (5.1%)
- Disorders of the visual cortex (4.1%)
- Cerebrovascular disease (3.2%)
- Degeneration of the macula and posterior pole (3.0%)
- Myopia (2.8%)
- Corneal disorders (2.6%)
- Malignant neoplasms of the brain and nervous system (1.5%)
- Retinal detachment (1.4%)
Types Eye Diseases
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Definitions of Vision Disorders in the Vision in Preschoolers Study.
Vision Disorder | Definitions |
---|---|
Hyperopia | Any hyperopia: >3.25 D in most positive meridian in either eye |
Hyperopia severity: | |
Group 1: ≥5.0 D | |
Group 2: >3.25D and <5.0D and interocular difference in SE of ≥0.5 D | |
Group 3: >3.25D and <5.0D and interocular difference in SE of <0.5 D | |
Anisometropia | >1.00D interocular difference in hyperopia; >3.00D interocular difference in myopia; >1.50D interocular difference in astigmatism; antimetropic difference >1.00D and one eye >1.00D of hyperopia; antimetropic difference >3.00D and one eye >2.00D of myopia |
Astigmatism | >1.50D between principal meridians |
Unilateral Amblyopia | ≥2-line interocular difference in VA and a unilateral amblyogenic factor† |
Bilateral Amblyopia | 3-year-olds : worse than 20/50 in one eye, worse than 20/40 in the contralateral eye, and a bilateral amblyogenic factor‡ |
4- and 5-year olds: worse than 20/40 in one eye, worse than 20/30 in the contralateral eye, and a bilateral amblyogenic factor‡ | |
Strabismus | Any heterotropia in primary gaze |
D=diopters; VA=Visual Acuity
Amblyopia -is a category of vision loss or visual impairment that is caused by factors unrelated to refractive errors or coexisting ocular diseases. Amblyopia is the condition when a child’s visual systems fail to mature normally because the child either suffers from a premature birth, measles, congenital nubella syndrome, vitamin A deficiency, or meningitis. If left untreated during childhood, amblyopia is currently incurable in adulthood because surgical treatment effectiveness changes as a child matures. Consequently, amblyopia is the world’s leading cause of child monocular vision loss, which is the damage or loss of vision in one eye. In the best case scenario, which is very rare, properly treated amblyopia patients can regain 20/40 acuity.
- Corneal opacification
- Degenerative myopia
- Diabetic retinopathy – is one of the manifestation microvascular complications of diabetes, which is characterized by blindness or reduced acuity. That is, diabetic retinopathy describes the retinal and vitreous hemorrhages or retinal capillary blockage caused by the increase of A1C, which a measurement of blood glucose or sugar level. In fact, as A1C increases, people tend to be at greater risk of developing diabetic retinopathy than developing other microvascular complications associated with diabetes (e.g. chronic hyperglycemia, diabetic neuropathy, and diabetic nephropathy). Despite the fact that only 8% of adults 40 years and older experience vision-threatening diabetic retinopathy (e.g. nonproliferative diabetic retinopathy or NPDR and proliferative diabetic retinopathy or PDR), this eye diseased accounted for 17% of cases of blindness in 2002.
- Retinitis pigmentosa
- Retinopathy of prematurity – The most common cause of blindness in infants worldwide. In its most severe form, ROP causes retinal detachment, with attendant visual loss. Treatment is aimed mainly at prevention, via laser or Avastin therapy.
- Stargardt’s disease
- Uveitis – is a group of 30 intraocular inflammatory diseases caused by infections, systemic diseases, organ-specific autoimmune processes, cancer or trauma. That is, uveitis refers to a complex category of ocular diseases that can cause blindness if either left untreated or improperly diagnosed. The current challenge of accurately diagnosing uveitis is that often the cause of a specific ocular inflammation is either unknown or multi-layered. Consequently, about 3–10% uveitis victims in developed countries, and about 25% of victims in the developing countries, become blind from incorrect diagnosis and from ineffectual prescription of drugs, antibiotics or steroids. In addition, uveitis is a diverse category of eye diseases that are subdivided as granulomatous (or tumorous) or non-granulomatous anterior, intermediate, posterior or pan uveitis. In other words, uveitis diseases tend to be classified by their anatomic location in the eye (e.g. uveal tract, retina, or lens), as well as can create complication that can cause cataracts, glaucoma, retinal damage, age-related mac
The Most Common Eye Disease
Acanthamoeba Keratitis
A rare but serious eye infection associated with poor contact lens hygiene and other factors.
Amblyopia (Lazy Eye)
Amblyopia is a vision development problem in infants and young children that can lead to permanent vision loss. Learn the symptoms, causes and treatments.
Anisocoria
Is one pupil bigger than the other? Learn about anisocoria (unequal pupils).
Astigmatism
Usually caused by an irregular cornea, astigmatism causes blur at all distances. Also see the Eye Doctor
Bell’s Palsy
This condition causes sudden paralysis of one side of the face. Because it affects blinking, it can cause severe dry eye.
Bionic Eye Implants
Learn about retinal implants that are restoring functional vision to people with retinitis pigmentosa and other blinding conditions.
Black Eye
How serious is a black eye? How to treat black eyes.
Blepharitis
Inflammation of the eyelids associated with chronic eye irritation, watery eyes, foreign body sensation, sensitivity to light and crusty debris at the base of the eyelashes.
Blurry Vision
Blurry vision has many causes, from fatigue and eyestrain to serious eye diseases such as glaucoma. A video helps explain blurry vision causes and treatments.
Burning Eyes
How to get relief from burning, stinging eyes.
Cataracts
The risk of cataracts increases with age. Learn what causes them and how to protect your eyes.
Chalazion
A swollen bump in the eyelid. Learn about causes and treatments.
Clinical Trials Related to Eye Diseases
Find out the status of clinical trials for treatment of glaucoma, macular degeneration, blepharitis and other eye problems and diseases.
CMV Retinitis
About 80 percent of adults have been exposed to the cytomegalovirus (CMV), but it mostly affects people with poor immune systems, such as AIDS patients.
Color Blindness
Learn the varieties of color vision deficiency and how to cope with color blindness.
Common Eye Disorders
How to identify and manage everyday eye problems.
Concussion, TBI and Vision
Up to 90 percent of people who suffer from concussion or other traumatic brain injury experience vision problems such as blurry vision, sensitivity to light and difficulties with eye movements. Learn what can be done.
Conjunctivitis (Pink Eye)
What you can do about redness, swelling, itching and tearing of pink eye.
Cornea Transplant
Eye injuries and diseases like keratoconus may require a cornea transplant, using healthy tissue from an eye donor.
Corneal Abrasion (Scratched Eye)
A scratched cornea is usually very painful. What to do if it happens to you.
Corneal Collagen Crosslinking
Not yet FDA-approved, these procedures can strengthen the front surface of the eye and help keratoconus patients avoid a cornea transplant.
Corneal Ulcer
Treatment may help prevent scarring on your eye.
Detached Retina
Flashes of light and floating spots are classic warning signs of a detached retina — get them checked out ASAP.
Diabetic Retinopathy
Damage to the eye’s retina due to diabetes. Also read about treatment for diabetic retinopathy and macular edema.
Different Colored Eyes (Heterochromia)
Many people (and animals) have two different colored eyes. What causes it? Is it a problem that requires an eye exam?
Double Vision (Diplopia)
Many conditions cause double vision, including stroke and cataracts. What to do.
Dry Eye Infographic
Learn eight symptoms, causes and steps to managing dry eye.
Eye Allergies
Itchy, red, swollen, tearing eyes may mean eye allergies. Get tips for relief, and read our Eye Doctor Q&Aabout common eye allergy symptoms.
Eye and Vision Product News
New eyewear and vision care products designed to improve your life.
Eye Herpes
Ocular herpes is a recurrent viral infection that may lead to serious vision loss. Read how herpes of the eye is transmitted and treated.
Eye Infections
Learn about bacterial, viral and fungal eye infections, including symptoms.
Eye Injury
Accidents cause many kinds of eye injuries, from corneal scratches to penetrating wounds. What to do for an eye emergency.
Eye Occlusions (Eye Strokes)
Sudden vision loss can occur when a clot or blockage interrupts blood flow to vital eye structures.
Eye Pain
How to know if a painful eye is an emergency.
Eye Twitching
Eyelid twitches, tics and spasms are maddening. Here are eight remedies you can try.
Floaters, Flashes and Spots
Eye floaters and flashes may be harmless, or they may signal a serious problem, like a detached retina.
Fuchs’ Corneal Dystrophy
Causes loss of vision and clouding of the cornea due to degeneration of the corneal endothelium and corneal edema.
Glaucoma
Glaucoma damages the optic nerve and diminishes the field of vision. Learn about glaucoma causes, eye drops for glaucoma, narrow-angle glaucoma, primary open-angle glaucoma and glaucoma surgery.
Glaucoma Surgery
New options for controlling glaucoma with surgery.
Higher-Order Aberrations
Higher-order aberrations (HOAs) are vision errors causing poor night vision or double images.
Hyperopia (Farsightedness)
Farsighted people can have poor near vision or blurred vision at all distances.
Hyphema
A hyphema is a broken blood vessel in the eye that causes blood to collect in the space between the cornea and iris. It’s usually painful and can cause glaucoma.
Intacs for Keratoconus
These tiny corneal inserts can help flatten a bulging eye.
Itchy Eyes
What causes itchy eyes and eyelids — and how to get relief.
Keratoconus
Special contact lenses can help this condition that changes the shape of your eye.
Macular Degeneration (AMD)
Our 10-page section covers this sight-threatening disease, plus FDA-approved macular degeneration treatments, investigational treatments, macular degeneration prevention,
Macular Dystrophy
Central vision loss can be associated with this inherited eye disease.
Macular Hole
Suddenly blurry or distorted vision, especially in seniors and diabetics, may mean a macular hole.
Meibomian Gland Dysfunction
MGD is the culprit behind most cases of dry eye syndrome. Find out how to spot it and what you can do to get relief.
Milia (Eyelid Cysts)
What causes those tiny eyelid cysts in babies and adults, and how they are treated.
Myopia (Nearsightedness)
Nearsighted people can see fine up close, but distant objects are a blur.
Nystagmus
Uncontrollable eye movements from nystagmus often have neurological causes.
Ocular Hypertension
High eye pressure has no symptoms, but can be easily detected in an eye exam. Learn what can be done to prevent glaucoma and possible eye damage.
Ocular Migraine
Ocular migraine causes a sensation of looking through shattered glass. What’s happening
Ocular Rosacea
How to solve eye and eyelid irritation.
Optic Neuritis and Optic Neuropathy
An inflamed optic nerve can cause blurry vision and blind spots.
Peripheral Vision Loss
“Tunnel vision” can have various causes, including glaucoma.
Photophobia (Light Sensitivity)
Sensitive to light? Many eye conditions can cause this problem.
Pinguecula
Pingueculae are growths on the eye. Are they serious?
Presbyopia
All about this normal age-related loss of focusing ability that becomes noticeable after age 40. Also, read answers to frequently asked questions for a quick overview.
Pterygium
Pterygia, also called “surfer’s eye,” are growths on the eyeball that can interfere with vision.
Ptosis (Drooping Eyelid)
Drooping eyelids can be corrected with ptosis repair surgery, which tightens the muscle that supports the upper eyelid.
Red Eyes
Red eyes can be caused by allergies, eye infections and eye injuries. Learn more causes of red eye and how to treat bloodshot eyes.
Retinitis Pigmentosa
Poor night vision and a narrowing field of vision beginning in childhood herald this rare disorder. Can vitamin A and beta-carotene help?
Sjogren’s Syndrome
Dry eye is a common symptom of this autoimmune disorder.
Sleep in Your Eyes
Do you often wake up with sticky, slimy, crusty “eye gunk”? This article explains where eye discharge comes from and when it’s cause for alarm.
Snow Blindness
How to prevent a painful sunburned eye and temporary vision loss from UV exposure.
Stargardt’s Disease (STGD)
A form of macular degeneration that affects children and young people.
Strabismus
Key facts about strabismus and crossed eyes, including causes and treatments (strabismus surgery, vision therapy and orthoptics).
Stye
What causes styes in your eyelid — and how to prevent them.
Stye Treatment – NEW!
How to get rid of a stye and keep them from coming back.
Subconjunctival Hemorrhage
Sudden redness in the white of your eye may be a subconjunctival hemorrhage.
Swollen Eyelids
Swollen eyes have many causes. Here are tips for prevention and treatment.
Uveitis
Painful inflammation of the uvea causes light sensitivity, floaters and blurred vision.
Vitrectomy & Vitreoretinal Procedures
These delicate surgical procedures for macular holes, retinal detachments and other conditions are performed in the eye’s deep interior.
Treatment of Eye Diseases
Mobility
Many people with serious visual impairments can travel independently, using a wide range of tools and techniques. Orientation and mobility specialists are professionals who are specifically trained to teach people with visual impairments how to travel safely, confidently, and independently in the home and the community. These professionals can also help blind people to practice travelling on specific routes which they may use often, such as the route from one’s house to a convenience store. Becoming familiar with an environment or route can make it much easier for a blind person to navigate successfully.
Reading and magnification/ Eye glash uses
Others read Braille (or the infrequently used Moon type), or rely on talking books and readers or reading machines, which convert printed text to speech or Braille. They use computers with special hardware such as scanners and refreshable Braille displays as well as software written specifically for the blind, such as optical character recognition applications and screen readers.
Some people access these materials through agencies for the blind, such as the National Library Service for the Blind and Physically Handicapped in the United States, the National Library for the
Computers and mobile technology
Access technology such as screen readers, screen magnifiers and refreshable Braille displays enable the blind to use mainstream computer applications and mobile phones. The availability of assistive technology is increasing, accompanied by concerted efforts to ensure the accessibility of information technology to all potential users, including the blind. Later versions of Microsoft Windows include an Accessibility Wizard & Magnifier for those with partial vision, and Microsoft Narrator, a simple screen reader. Linux distributions (as live CDs) for the blind include Vinux and Adriane Knoppix, the latter developed in part by Adriane Knopper who has a visual impairment. macOS and iOS also come with a built-in screen reader called VoiceOver, while Google TalkBack is built in to most Android devices.
Eye Diseases Treatment in Developing Country
The definition of visual impairment is reduced vision not corrected by glasses or contact lenses. The World Health Organization uses the following classifications of visual impairment. When the vision in the better eye with best possible glasses correction is:
- 20/30 to 20/60 : is considered mild vision loss, or near-normal vision
- 20/70 to 20/160 : is considered moderate visual impairment, or moderate low vision
- 20/200 to 20/400 : is considered severe visual impairment, or severe low vision
- 20/500 to 20/1,000 : is considered profound visual impairment, or profound low vision
- More than 20/1,000 : is considered near-total visual impairment, or near total blindness
- No light perception : is considered total visual impairment, or total blindness
Blindness is defined by the World Health Organization as vision in a person’s best eye with best correction of less than 20/500 or a visual field of less than 10 degrees. This definition was set in 1972, and there is ongoing discussion as to whether it should be altered to officially include uncorrected refractive errors.
United Kingdom
Severely sight impaired
- Defined as having central visual acuity of less than 3/60 with normal fields of vision, or gross visual field restriction.
- Unable to see at 3 metres what the normally sighted person sees at 60 m.
Sight impaired
- Able to see at 3 m, but not at 6 m, what the normally sighted person sees at 60 m
- Less severe visual impairment is not captured by registration data, and its prevalence is difficult to quantify
Low vision
- A visual acuity of less than 6/18 but greater than 3/60.
- Not eligible to drive and may have difficulty recognising faces across a street, watching television, or choosing clean, unstained, co-ordinated clothing.
In the UK, the Certificate of Vision Impairment (CVI) is used to certify patients as severely sight impaired or sight impaired. The accompanying guidance for clinical staff states: “The National Assistance Act 1948 states that a person can be certified as severely sight impaired if they are “so blind as to be unable to perform any work for which eye sight is essential”. The test is whether a person cannot do any work for which eyesight is essential, not just his or her normal job or one particular job.”
In practice, the definition depends on individuals’ visual acuity and the extent to which their field of vision is restricted. The Department of Health identifies three groups of people who may be classified as severely visually impaired.
- Those below 3/60 (equivalent to 20/400 in US notation) Snellen (most people below 3/60 are severely sight impaired).
- Those better than 3/60 but below 6/60 Snellen (people who have a very contracted field of vision only).
- Those 6/60 Snellen or above (people in this group who have a contracted field of vision especially if the contraction is in the lower part of the field).
The Department of Health also state that a person is more likely to be classified as severely visually impaired if their eyesight has failed recently or if they are an older individual, both groups being perceived as less able to adapt to their vision loss.
United States
In the United States, any person with vision that cannot be corrected to better than 20/200 in the best eye, or who has 20 degrees (diameter) or less of visual field remaining, is considered legally blind or eligible for disability classification and possible inclusion in certain government sponsored programs.
In the United States, the terms partially sighted, low vision, legally blind and totally blind are used by schools, colleges, and other educational institutions to describe students with visual impairments.They are defined as follows:
- Partially sighted indicates some type of visual problem, with a need of person to receive special education in some cases.
- Low vision generally refers to a severe visual impairment, not necessarily limited to distance vision. Low vision applies to all individuals with sight who are unable to read the newspaper at a normal viewing distance, even with the aid of eyeglasses or contact lenses. They use a combination of vision and other senses to learn, although they may require adaptations in lighting or the size of print, and, sometimes, Braille.
- Myopic – unable to see distant objects clearly, commonly called near-sighted or short-sighted.
- Hyperopic – unable to see close objects clearly, commonly called far-sighted or long-sighted.
- Legally blind indicates that a person has less than 20/200 vision in the better eye after best correction (contact lenses or glasses), or a field of vision of less than 20 degrees in the better eye.
- Totally blind students learn via Braille or other non-visual media.
References
- WHO ICD-10 — Chapter VII Diseases of the eye and adnexa (H00-H59)
- “Change the Definition of Blindness” (PDF). World Health Organization. Archived (PDF) from the original on 14 July 2015. Retrieved 23 May 2015.
- Blindness and Vision Impairment”. February 8, 2011. Archived from the original on 29 April 2015. Retrieved 23 May 2015.
- Visual impairment and blindness Fact Sheet N°282″. August 2014. Archived from the original on 12 May 2015. Retrieved 23 May2015.
- GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). “Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015”. Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577 . PMID 27733282.
- Maberley, DA; Hollands, H; Chuo, J; Tam, G; Konkal, J; Roesch, M; Veselinovic, A; Witzigmann, M; Bassett, K (March 2006). “The prevalence of low vision and blindness in Canada”. Eye (London, England). 20 (3): 341–6. doi:10.1038/sj.eye.6701879. PMID 15905873.
- GLOBAL DATA ON VISUAL IMPAIRMENTS 2010 (PDF). WHO. 2012. p. 6. Archived (PDF) from the original on 2015-03-31.
- Sack RL, Lewy AJ, Blood ML, Keith LD, Nakagawa H (July 1992). “Circadian rhythm abnormalities in totally blind people: incidence and clinical significance”. J. Clin. Endocrinol. Metab. 75 (1): 127–34. doi:10.1210/jc.75.1.127. PMID 1619000.
- Bunce, C; Wormald, R (2006). “Leading causes of certification for blindness and partial sight in England & Wales”. BMC Public Health. 6: 58. doi:10.1186/1471-2458-6-58. PMC 1420283 . PMID 16524463.
- Liew, Gerald; Michaelides, Michel; Bunce, Catey (February 2014). “A comparison of the causes of blindness certifications in England and Wales in working age adults (16–64 years), 1999–2000 with 2009–2010”. BMJ Open. 4 (2): e004015. doi:10.1136/bmjopen-2013-004015. ISSN 2044-6055. PMC 3927710 . PMID 24525390.
- “Statistics and Sources for Professionals.” American Foundation for the Blind Archived 2008-08-07 at the Wayback Machine.
- “Defining the Boundaries of Low Vision Patients”. SSDI Qualify. Archived from the original on January 27, 2014. Retrieved January 22,2014.
- “Low Vision and Legal Blindness Terms and Descriptions”. American Foundation for the Blind. Archived from the original on 2017-03-01. Retrieved 2017-02-28.