A tongue‑muscle infection happens when germs (usually bacteria, sometimes viruses, fungi or parasites) inflame the intrinsic and extrinsic muscles that make your tongue move, shape food and help you talk and breathe. Doctors also call it lingual cellulitis, focal tongue myositis, Ludwig’s angina (when infection spreads under the tongue) or infectious glossitis. Untreated, it can swell quickly and block the airway, so early attention is vital. WebMDCleveland Clinic
Anatomy
Key Point | Plain‑English Explanation |
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Structure & location | Your tongue sits on the floor of the mouth, anchored to the hyoid bone and mandible, and is covered by a moist mucous membrane. |
Intrinsic muscles (4) | Superior longitudinal, inferior longitudinal, transverse, vertical – start and end inside the tongue. They change its shape for speech and swallowing. TeachMeAnatomy |
Extrinsic muscles (4) | Genioglossus, hyoglossus, styloglossus, palatoglossus – originate outside, insert into the tongue, move it in/out, up/down, side/side. Palatoglossus is the only one not controlled by the hypoglossal nerve. TeachMeAnatomyKenhub |
Origins & insertions | • Genioglossus → mental spine → tongue body & hyoid. • Hyoglossus → hyoid → tongue sides. • Styloglossus → styloid process → tongue sides. • Palatoglossus → soft palate → tongue dorsum. Geeky Medics |
Blood supply | Main pipeline is the lingual artery (deep, dorsal & sublingual branches) with back‑up from tonsillar and ascending pharyngeal branches. Veins follow the same route. KenhubCleveland Clinic |
Nerve supply | Motor: Hypoglossal nerve (CN XII) for all muscles except palatoglossus (vagus, CN X). Sensory: Lingual nerve (front ⅔ touch), chorda tympani (front ⅔ taste), glossopharyngeal (back ⅓), vagus (root). TeachMeAnatomy |
Six headline functions | 1) Chewing (keeps food on teeth) 2) Swallowing (pushes bolus backward) 3) Speech & singing (articulates sounds) 4) Taste positioning (moves toward taste buds) 5) Airway protection (seals oropharynx) 6) Oral cleansing (sweeps debris). Hospital for Special Surgery |
Main types of tongue‑muscle infection
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Acute bacterial cellulitis (most common; often Streptococcus or Staphylococcus)
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Suppurative abscess / pyomyositis (pus pocket inside tongue muscle)
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Ludwig’s angina (rapid cellulitis beneath the tongue)
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Viral myositis (e.g., influenza, Coxsackie)
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Fungal glossitis (Candida thrush in immunosuppressed)
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Parasitic myositis (Trichinella larvae in emigrating muscle)
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Auto‑immune overlap (dermatomyositis‐related lingual myositis)
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Radiation‑induced secondary infection
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Traumatic contaminated wound infection
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Iatrogenic (after piercing, biopsy or intubation) RadiopaediaRadiopaedia
Common causes
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Poor oral hygiene
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Dental caries / abscess spreading
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Trauma from sharp tooth or dentures
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Tongue piercing
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Burns from hot food
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Upper‑respiratory infection spread
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Sinus or tonsil infection tracking along fascial planes
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Diabetes (weak immunity)
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Iron, B12 or folate deficiency (glossitis)
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Steroid or immunosuppressant use
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HIV or other immunodeficiency
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Viral illnesses (flu, hand‑foot‑and‑mouth)
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Fungal overgrowth after antibiotics
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Parasite ingestion in under‑cooked meat
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Allergic reaction causing cracks that get infected
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Tobacco or heavy alcohol (irritates mucosa)
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Gastro‑esophageal reflux acid burns
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Radiation therapy to head‑neck
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Chemotherapy mucositis
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Inadequate saliva (dry mouth) promoting bacterial growth Cleveland ClinicMedical News Today
Symptoms (you may have some, not all)
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Sudden tongue pain or burning
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Swelling / thick tongue
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Redness or deep beefy color
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White, yellow or green coating
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Pus pockets or ulcers
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Difficulty moving tongue
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Slurred speech
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Drooling
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Difficulty chewing
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Trouble swallowing (dysphagia)
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Choking sensation
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Muffled “hot‑potato” voice
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Metallic or foul taste
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Bad breath (halitosis)
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Fever & chills
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Jaw or neck stiffness
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Earache (referred pain)
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Tender lymph nodes under jaw
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Airway noise or stridor
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Fatigue / malaise WebMDCleveland ClinicCleveland Clinic
Diagnostic tests doctors may use
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Full mouth & neck exam (mirror + gloved palpation)
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Vital‑sign check (airway, breathing, circulation)
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Complete blood count (look for high white cells)
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C‑reactive protein & ESR (inflammation markers)
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Blood cultures (rule‑out sepsis)
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Swab culture of exudate
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Gram stain / PCR (rapid germ ID)
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MRI of tongue – best for muscle edema & abscess mapping American Journal of Roentgenology
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CT scan with contrast – shows deep‑space spread
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Ultrasound – bedside screening for fluid pockets
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Plain X‑ray soft‑tissue neck – airway narrowing
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Fiber‑optic nasoendoscopy – airway inspection
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Laryngoscopy (if voice changes)
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Taste‑bud & nerve tests
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Electromyography (check muscle function)
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Biopsy (exclude cancer or autoimmune myositis) ScienceDirectRadiopaedia
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Serology for viruses (EBV, Coxsackie)
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Fungal culture or KOH prep
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Parasite serology (Trichinella ELISA)
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Nutrient panel (iron, B‑vitamins)
Non‑pharmacological treatments you can start or your clinician may prescribe
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Warm salt‑water gargles 3‑4×/day
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Good oral hygiene – soft brush, floss, tongue scraper
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Ice chips or cold smoothies to ease pain
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Soft diet (puree, yogurt) until swelling eases
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Hydration goal: 2–3 L water/day
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Speech‑language therapy for swallowing techniques (chin‑tuck, effortful swallow) Hospital for Special SurgeryThe Myositis Association
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Targeted tongue‑strength exercises (Masako, tongue protrusion, lingual resistance) understandingmyositis.orgHome
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Postural adjustments (side lying, head tilt) while eating
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Small frequent meals instead of big plates
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Avoid spicy, acidic, hot foods
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Cold compress on the neck
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Humidified air or steam inhalation
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Sugar‑free lozenges / saliva substitutes if dry mouth
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Quit tobacco and vaping
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Limit alcohol (dries mucosa)
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Manage reflux (raise head of bed)
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Vitamin & mineral repletion (iron, B12, folate)
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Blood‑sugar control in diabetes
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Regular dental check‑ups and quick cavity repair
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Remove or smooth sharp dental edges
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Replace ill‑fitting dentures
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Piercing after‑care or removal
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Protective mouth guard for nighttime grinding
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Stress management & good sleep (supports immunity)
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Monitoring diary of pain, swelling, drugs taken
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Cool‑mist peroxide mouth rinse (per prescriber)
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Topical honey or aloe vera (natural demulcents)
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Probiotic yogurt to re‑balance oral flora
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Weight management & exercise (improves circulation)
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Follow‑up appointments to track healing
Commonly used drugs (examples – your doctor chooses the right one)
Category | Typical choices & notes |
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First‑line oral antibiotics | Amoxicillin‑clavulanate, cephalexin, clindamycin (covers strep/staph) MedscapeIDSA Home |
MRSA‑cover agents | Trimethoprim‑sulfamethoxazole, doxycycline, linezolid |
Broad IV antibiotics (severe cases) | Piperacillin‑tazobactam, ceftriaxone ± metronidazole, vancomycin |
Antifungals | Nystatin suspension, fluconazole |
Antivirals | Acyclovir, oseltamivir (if viral trigger) |
Antiparasitics | Albendazole (Trichinella) |
Analgesics / antipyretics | Paracetamol, ibuprofen |
Topical anesthetic gels | Lidocaine 2 % viscous |
Steroid mouth rinse (short course) | Dexamethasone oral rinse – reduces severe swelling |
Proton‑pump inhibitor | Omeprazole if acid reflux worsens pain |
Vitamin therapies | High‑dose B12, folic acid, iron (if deficiency) |
Antiseptic rinses | Chlorhexidine 0.12 % |
Mucosal protectants | Benzydamine oral rinse |
Immune‑modulators | Prednisone, IVIG, methotrexate if autoimmune myositis |
Mucolytics | Acetylcysteine gargle |
Saliva stimulants | Pilocarpine tablets |
Antiemetics | Ondansetron for nausea from antibiotics |
Antihistamines | Cetirizine for allergic swelling trigger |
Opioid rescue (short term) | Tramadol when NSAIDs inadequate |
Probiotic capsules | Rebalance gut flora after antibiotics |
Always follow the exact dose and length your healthcare professional prescribes; stopping early invites relapse.
Surgical or procedural options (for emergencies or complications)
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Needle aspiration of localized tongue abscess
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Incision & drainage under local or general anesthesia
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Wide excision / debridement of necrotic tissue
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Airway protection with endotracheal intubation
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Emergency tracheostomy when swelling blocks airway (life‑saving) Cleveland Clinic
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Video‑assisted drainage of submandibular space (Ludwig’s angina)
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Vacuum‑assisted wound closure for deep cavities
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Feeding gastrostomy if prolonged dysphagia
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Laser ablation of stubborn granulation tissue
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Corrective plastic surgery (Z‑plasty) for fibrosis restricting tongue mobility
Smart ways to prevent tongue‑muscle infection
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Brush, floss and clean your tongue twice daily
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Book a dental visit every 6 months
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Fix cavities, cracked teeth and dentures early
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Avoid sharing toothbrushes, utensils or mouth guards
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Disinfect tongue piercings; keep jewelry clean
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Treat strep throat, sinus or tooth infections promptly
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Control chronic illnesses (diabetes, reflux, anemia)
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Quit smoking and limit alcohol
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Stay hydrated and eat a nutrient‑rich diet
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Get flu vaccine and follow food‑safety rules for meat
When should you see a doctor right away?
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Difficulty breathing, noisy breathing or drooling
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Rapidly increasing tongue swelling
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High fever > 38.5 °C (101.3 °F)
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Inability to swallow saliva or liquids
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Severe pain unrelieved by over‑the‑counter medicine
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New weakness, numbness or tongue paralysis
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Symptoms last > 7 days or keep coming back
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Any immunocompromised state (HIV, chemo, steroids)
Early medical help prevents suffocation, sepsis and long‑term loss of tongue movement. Cleveland ClinicWebMD
Frequently Asked Questions (FAQs)
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Is a tongue‑muscle infection contagious?
Mostly no, but the germs causing it (strep, flu, thrush) can spread through saliva droplets. -
How long does it take to heal?
Mild cases clear in 7–10 days with antibiotics; deep abscesses may need weeks and therapy. -
Can I treat it at home?
Home care helps but you still need a professional exam to rule out airway risk. -
Will I lose my sense of taste?
Temporary dullness is common; permanent loss is rare once swelling settles. -
What foods are safest while healing?
Cool, smooth, non‑acidic foods like yogurt, oatmeal, mashed banana. -
Why does my tongue feel numb after treatment?
Lidocaine gel, nerve pressure from swelling or surgical trauma usually resolve in days. -
Is salt‑water gargle enough?
Gargles ease pain but do not replace needed antibiotics or drainage. -
Do I have to remove my tongue piercing?
Yes, until infection clears; metal can trap bacteria. -
What happens if I ignore the infection?
It can spread to the neck and chest, block the airway and become fatal. -
Can I keep taking my dentures out at night only?
During infection keep them out most of the day to reduce pressure. -
Why did my tongue swell after antibiotics finished?
Possible drug‑resistant germ or early stop; see your doctor for culture. -
Are probiotics useful?
Yes, they cut risk of thrush after broad antibiotics. -
Could this be cancer instead?
Chronic non‑healing ulcers or lumps warrant biopsy to rule out malignancy. -
Can children get tongue‑muscle infections?
Yes, but they’re rarer; kids with Kawasaki disease or scarlet fever can show “strawberry tongue.” Verywell Health -
Does COVID‑19 cause tongue myositis?
COVID can trigger loss of taste and mouth ulcers, but true tongue‑muscle infection is unusual.
Tongue‑muscle infections are uncommon but can escalate fast. Keep your mouth clean, treat early, finish antibiotics, and practice the swallowing and tongue‑strength exercises your therapist teaches. If breathing or swallowing suddenly worsens, call emergency services—seconds count.
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The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members
Last Updated: April 17, 2025.