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Teneligliptin Drug; Mechanism, Uses, Dosage, Side effects, Interaction

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Drugs (A - Z), Rx Journal of Fitness & Clinical Research
  • Mechanism of action of Teneligliptin
  • Indications of Teneligliptin
  • Side Effects of Teneligliptin
  • Drug Interaction of Teneligliptin
Teneligliptin is a long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels. Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus

Teneligliptin is an antidiabetic medicine used in the treatment of type 2 diabetes in adult patients. Patients are advised to follow a strict diet and exercise regimen along with this medicine for the best possible effect. This medicine is not recommended for use in children.

Mechanism of action of Teneligliptin

Teneligliptin is a long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels. It is a long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels. Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus

Indications of Teneligliptin

  • Type 2 Diabetes Mellitus

Side Effects of Teneligliptin

Most common

  • Abdominal or stomach discomfort
  • increased urination.
  • low blood pressure,
  • difficult, burning, or painful urination
  • discharge with a strong odor from the penis
  • increased potassium blood levels (hyperkalemia),
  • low blood sugar (hypoglycemia), and
  • diarrhea
  • gas (flatulence)
  • symptoms of weakness, muscle pain (myalgia)
  • upper respiratory tract infection
  • low blood sugar (hypoglycemia)
  • abdominal pain (GI complaints), lactic acidosis (rare)
  • low blood levels of vitamin B-12
  • nausea,vomiting
  • chest discomfort
  • chills, dizziness
  • bloating/abdominal distention
  • constipation
  • heartburn

More common

  • Abdominal or stomach discomfort
  • cough or hoarseness
  • decreased appetite
  • diarrhea
  • fast or shallow breathing
  • fever or chills
  • general feeling of discomfort
  • lower back or side pain
  • muscle pain or cramping
  • painful or difficult urination

Drug Interaction of Teneligliptin

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
  • Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  •  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption

 Teneligliptin may interact with following drugs ,supplyments & may decrease the efficacy of drug

  • Beta blockers
  • Levo-Thyroxine
  • MAO inhibitors
  • Disease

    Information not available.

Food interactions

  • Information not available.

Teneligliptin is on going clinical trial…details coming soon…………………………..

References

  1. DrugBank

    http://www.drugbank.ca/drugs/DB11950

  2. ClinicalTrials.gov

    https://clinicaltrials.gov/

  3. NCIt

    https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C87623

  4. FDA/SPL Indexing Data
    28ZHI4CF9C

    https://www.fda.gov/ForIndustry/DataStandards/SubstanceRegistrationSystem-UniqueIngredientIdentifierUNII/

  5. Springer Nature
    Literature references related to scientific contents from Springer Nature journals and books. Read more …
  6. Wikipedia
    teneligliptin hydrobromide hydrate

    https://www.wikidata.org/wiki/Q27251739

    teneligliptin

    https://en.wikipedia.org/wiki/Teneligliptin

    https://www.wikidata.org/wiki/Q27261290

  7. PubChem
    Data deposited in or computed by PubChem

    https://pubchem.ncbi.nlm.nih.gov

Teneligliptin

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Teneligliptin Drug; Mechanism, Uses, Dosage, Side effects, Interaction
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