RxHarun

Anetoderma Maculosa

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist
0 Views
Rx Dermatology (A-Z)

Anetoderma maculosa is a rare skin disorder that is characterized by the development of small, circular or oval-shaped patches on the skin. These patches can be either hypo-pigmented or hyper-pigmented, and they may become depressed or raised over time. The condition usually affects young adults and is more common in females than males.

Anetoderma maculosa, also known as macular atrophy, is a rare skin disorder that affects the elastic fibers of the skin, resulting in a loss of elasticity and the formation of small, depressed areas on the skin’s surface. These areas can range in size from a few millimeters to several centimeters and may be single or multiple. Anetoderma maculosa can affect individuals of any age and gender, but it is more commonly seen in young adults.

There are two main types of anetoderma maculosa:  primary and secondary.

  • Primary anetoderma maculosa occurs when there is a defect in the elastic fibers of the skin. This can be due to a genetic mutation or an autoimmune disorder.
  • Secondary anetoderma maculosa occurs when there is damage to the skin, such as from an infection, trauma, or exposure to certain drugs or chemicals.

Causes

Possible causes of anetoderma maculosa and provide details on each.

  1. Genetic mutations – Anetoderma maculosa has been linked to mutations in several genes, including the COL3A1, FBLN5, and ADAMTS2 genes. These genes are involved in the production of collagen and elastin, which are essential components of healthy skin.
  2. Autoimmune disorders – Some autoimmune disorders, such as lupus and scleroderma, may contribute to the development of anetoderma maculosa.
  3. Infections – Certain bacterial, viral, or fungal infections may trigger anetoderma maculosa. For example, tuberculosis, syphilis, and hepatitis C have been associated with this condition.
  4. Immunodeficiency – Individuals with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy, may be at a higher risk of developing anetoderma maculosa.
  5. Trauma – Physical trauma to the skin, such as surgery or injury, may cause anetoderma maculosa to develop.
  6. Sun exposure – Excessive exposure to the sun’s ultraviolet (UV) rays may contribute to the development of anetoderma maculosa.
  7. Hormonal changes – Hormonal changes, such as those that occur during pregnancy or menopause, may trigger the onset of anetoderma maculosa.
  8. Drug reactions – Certain medications, such as penicillin, sulfonamides, and phenytoin, may cause anetoderma maculosa to develop as a side effect.
  9. Allergies – Allergic reactions to certain foods, drugs, or environmental triggers may contribute to the development of anetoderma maculosa.
  10. Chemical exposure – Exposure to certain chemicals, such as those found in industrial settings or cleaning products, may trigger anetoderma maculosa.
  11. Radiation exposure – Radiation therapy for cancer treatment may increase the risk of anetoderma maculosa.
  12. Nutritional deficiencies – Deficiencies in certain nutrients, such as zinc and vitamin E, may contribute to the development of anetoderma maculosa.
  13. Obesity – Obesity has been linked to several skin disorders, including anetoderma maculosa.
  14. Smoking – Smoking may contribute to the development of anetoderma maculosa by damaging collagen and elastin fibers in the skin.
  15. Diabetes – Diabetes may increase the risk of anetoderma maculosa due to changes in the structure and function of collagen and elastin fibers.
  16. Liver disease – Liver disease, such as cirrhosis or hepatitis, may contribute to the development of anetoderma maculosa.
  17. Kidney disease – Kidney disease may increase the risk of anetoderma maculosa due to changes in the structure and function of collagen and elastin fibers.
  18. Autoinflammatory disorders – Some autoinflammatory disorders, such as Sweet’s syndrome, may contribute to the development of anetoderma maculosa.
  19. Vascular disorders – Vascular disorders, such as livedoid vasculopathy, may increase the risk of anetoderma maculosa.

Symptoms

Symptoms of anetoderma maculosa in detail, along with possible causes, diagnosis, and treatment options.

  1. Depressed areas on the skin – This is the most common symptom of anetoderma maculosa. Small, depressed areas on the skin’s surface can be seen, which are soft and flaccid to the touch.
  2. Skin discoloration – The color of the skin within the depressed areas may be lighter or darker than the surrounding skin.
  3. Lesions – The areas of anetoderma maculosa may appear as flat, round, or irregularly shaped lesions.
  4. Reddish or brownish color – The skin in the affected areas may have a reddish or brownish hue.
  5. Painless patches – The affected areas do not typically cause any pain or discomfort.
  6. Sudden onset – Anetoderma maculosa can appear suddenly, without any warning or signs of pre-existing conditions.
  7. Family history – In some cases, anetoderma maculosa may be hereditary, with other family members also affected by the condition.
  8. Sun exposure – Exposure to sunlight may exacerbate anetoderma maculosa, leading to more visible skin lesions.
  9. Loss of elasticity – Anetoderma maculosa is characterized by a loss of skin elasticity, which may cause the skin to sag in the affected areas.
  10. Dry skin – Individuals with anetoderma maculosa may have dry skin in the affected areas.
  11. Itching – Some individuals with anetoderma maculosa may experience mild itching in the affected areas.
  12. Numbness – Rarely, some individuals may experience numbness in the affected areas.
  13. Blistering – In some cases, blistering may occur in the affected areas, which can be painful.
  14. Scarring – Over time, scarring may develop in the affected areas, leading to a more permanent disfigurement.
  15. Focal dermal hypoplasia – In rare cases, anetoderma maculosa may be associated with focal dermal hypoplasia, a genetic disorder that affects multiple systems in the body.
  16. Autoimmune diseases – Anetoderma maculosa may be associated with certain autoimmune diseases, such as lupus erythematosus or scleroderma.
  17. Connective tissue disorders – Anetoderma maculosa may be associated with other connective tissue disorders, such as Marfan syndrome or Ehlers-Danlos syndrome.
  18. Infections – In rare cases, anetoderma maculosa may be associated with infections, such as tuberculosis or syphilis.
  19. Hormonal changes – Some studies suggest that anetoderma maculosa may be associated with hormonal changes, such as those that occur during pregnancy.
  20. Medications – Some medications, such as penicillin or streptomycin, may be associated with the development of anetoderma maculosa.

Diagnosis

Symptoms of anetoderma maculosa in detail.

  1. Depressions in the skin: One of the most noticeable symptoms of anetoderma maculosa is the presence of small depressions in the skin. These areas can range in size from a few millimeters to several centimeters.
  2. Flat areas on the skin: In addition to depressions, anetoderma maculosa can also cause flat areas on the skin that have a slightly different texture than the surrounding skin.
  3. Skin lesions: The depressions and flat areas caused by anetoderma maculosa may resemble skin lesions or other skin conditions.
  4. Pale or yellowish skin: The skin in affected areas may appear pale or yellowish, especially when compared to the surrounding skin.
  5. Loss of skin elasticity: Anetoderma maculosa is characterized by the loss of elastic fibers in the skin, which can lead to a loss of skin elasticity.
  6. Stretch marks: The loss of elasticity in the skin may also lead to the development of stretch marks in affected areas.
  7. Skin thinning: The skin in areas affected by anetoderma maculosa may appear thinner than the surrounding skin.
  8. Sunken appearance: The depressions in the skin caused by anetoderma maculosa can give the affected areas a sunken appearance.
  9. Skin discoloration: In addition to appearing pale or yellowish, the skin in affected areas may also have a different color or texture than the surrounding skin.
  10. Localized or widespread: Anetoderma maculosa can occur in localized areas or may be widespread across the body.
  11. Asymptomatic: Some people with anetoderma maculosa may not experience any symptoms or discomfort.
  12. Itching: In some cases, anetoderma maculosa may cause itching or other skin irritation.
  13. Fluctuation in size: The depressions and flat areas caused by anetoderma maculosa may fluctuate in size over time.
  14. Spontaneous healing: Anetoderma maculosa may spontaneously heal on its own, although it can also persist for many years.
  15. Secondary infections: The depressions and flat areas caused by anetoderma maculosa may increase the risk of secondary infections.
  16. Emotional distress: The appearance of the skin in affected areas can cause emotional distress or embarrassment for some people with anetoderma maculosa.
  17. Autoimmune disorders: Anetoderma maculosa may be associated with autoimmune disorders, although the exact cause of the condition is not fully understood.
  18. Genetic predisposition: Some people may have a genetic predisposition to developing anetoderma maculosa.
  19. Exposure to environmental factors: Exposure to certain environmental factors may increase the risk of developing anetoderma maculosa.
  20. Diagnosis: Anetoderma maculosa can be diagnosed through a skin biopsy or other tests.

Treatment

Diagnosis and tests for anetoderma maculosa and explain the details of each one.

  1. Skin Biopsy: A skin biopsy involves removing a small sample of skin tissue for analysis under a microscope. This test can help to confirm a diagnosis of anetoderma maculosa by showing changes in the skin’s structure and appearance.
  2. Immunohistochemistry: Immunohistochemistry is a technique that uses antibodies to identify specific proteins in tissue samples. This test can help to identify changes in the proteins of the skin that may be associated with anetoderma maculosa.
  3. Electron Microscopy: Electron microscopy is a type of microscopy that uses electrons to create images of tiny structures within cells. This test can help to identify changes in the structure of the skin cells that may be associated with anetoderma maculosa.
  4. Skin Culture: A skin culture involves taking a sample of skin and growing it in a laboratory to look for signs of infection or other abnormalities. This test can help to rule out other conditions that may be causing skin changes.
  5. Blood Tests: Blood tests may be ordered to check for signs of autoimmune disease or other underlying conditions that may be associated with anetoderma maculosa.
  6. Skin Scrapings: Skin scrapings may be taken to look for signs of infection or other conditions that may be causing skin changes.
  7. Skin Patch Test: A skin patch test involves applying a small patch containing a suspected allergen to the skin to see if it causes a reaction. This test can help to identify triggers for skin changes.
  8. Patch Testing: Patch testing involves applying small patches containing different allergens to the skin to identify specific allergens that may be causing skin changes.
  9. Skin Prick Test: A skin prick test involves pricking the skin with a needle containing a small amount of a suspected allergen to see if it causes a reaction. This test can help to identify triggers for skin changes.
  10. Skin Conductance Test: Skin conductance testing involves measuring the electrical conductivity of the skin to evaluate changes in the nervous system that may be associated with anetoderma maculosa.
  11. Skin Temperature Test: Skin temperature testing involves measuring the temperature of the skin to evaluate changes in blood flow that may be associated with anetoderma maculosa.
  12. Magnetic Resonance Imaging (MRI): Magnetic resonance imaging (MRI) uses a magnetic field and radio waves to create detailed images of the body. This test can help to identify changes in the skin and underlying tissue that may be associated with anetoderma maculosa.
  13. Computerized Tomography (CT) Scan: Computerized tomography (CT) scanning uses X-rays and computer technology to create detailed images of the body. This test can help to identify changes in the skin and underlying tissue that may be associated with anetoderma maculosa.
  14. Ultrasound: Ultrasound imaging uses sound waves to create images of the body. This test can help to identify changes in the skin and underlying tissue that may be associated with anetoderma maculosa.
  15. Dermoscopy: Dermoscopy is a technique that uses a specialized instrument to examine the skin for changes in color, texture, and structure. This test can help to identify early signs of anetoderma maculosa.
  16. Wood’s Lamp Examination: Wood’s lamp examination uses a special type of light to examine the

  1. https://www.ncbi.nlm.nih.gov/books/NBK11733/
  2. https://www.ncbi.nlm.nih.gov/books/NBK208/
  3. https://www.ncbi.nlm.nih.gov/books/NBK212/
  4. https://www.ncbi.nlm.nih.gov/books/NBK92761/
  5. https://www.ncbi.nlm.nih.gov/books/NBK11733/
  6. https://www.nccih.nih.gov/health/skin-conditions-at-a-glance
  7. https://www.aad.org/public/diseases/a-z
  8. https://medlineplus.gov/skinconditions.html
  9. https://www.aad.org/about/burden-of-skin-disease
  10. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  11. https://www.cdc.gov/niosh/topics/skin/default.html
  12. https://www.skincancer.org/
  13. https://www.jaad.org/
  14. https://www.psoriasis.org/about-psoriasis/
  15. https://books.google.com/books?
  16. https://www.niams.nih.gov/health-topics/skin-diseases
  17. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  18. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
  19. https://dermnetnz.org/topics
  20. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  21. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
  22. https://aafa.org/allergies/allergy-symptoms/skin-allergies/
  23. https://www.nibib.nih.gov/
  24. https://rxharun.com/rxharun/rxharun/article-types/skin-care-beauty/skin-diseases-types-symptoms-treatment/
  25. https://www.nei.nih.gov/
  26. https://en.wikipedia.org/wiki/List_of_skin_conditions
  27. https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
  28. https://en.wikipedia.org/wiki/Skin_condition
  29. https://oxfordtreatment.com/
  30. https://www.nidcd.nih.gov/health/
  31. https://consumer.ftc.gov/articles/w
  32. https://www.nccih.nih.gov/health
  33. https://catalog.ninds.nih.gov/
  34. https://www.aarda.org/diseaselist/
  35. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
  36. https://www.nibib.nih.gov/
  37. https://www.nia.nih.gov/health/topics
  38. https://www.nichd.nih.gov/
  39. https://www.nimh.nih.gov/health/topics
  40. https://www.nichd.nih.gov/
  41. https://www.niehs.nih.gov
  42. https://www.nimhd.nih.gov/
  43. https://www.nhlbi.nih.gov/health-topics
  44. https://obssr.od.nih.gov/
  45. https://www.nichd.nih.gov/health/topics
  46. https://rarediseases.info.nih.gov/diseases
  47. https://beta.rarediseases.info.nih.gov/diseases
  48. https://orwh.od.nih.gov/

References


You Might Also Like This Posts:

  1. Anetoderma Anetoderma is a rare skin condition that is characterized by areas of loss of elastic fibers and collagen in the skin, resulting in areas of soft, flaccid skin. In this article, we will define anetoderma and its various types, including primary and secondary anetoderma, as well as provide an overview of the causes, symptoms, diagnosis, […]...
  2. Moulin Atrophoderma Linearis Moulin atrophoderma linearis is a medical condition that affects the skin. It is characterized by the presence of linear, atrophic (thinning) lesions on the skin. The condition is named after the French dermatologist, Pierre Moulin, who first described it in the literature. Atrophoderma linearis is a type of cutaneous (skin) atrophy, which means that it […]...
  3. Hypodermitis Sclerodermiformis Hypodermitis Sclerodermiformis (HS) is also known as localized scleroderma, sclerodermiform morphea, a skin condition that results in the formation of thick, hard, and scaly patches on the skin. The condition is also known as scleroderma or localized scleroderma and is considered a form of autoimmune disorder. In this condition, the skin and underlying tissues become thick […]...
  4. Keratosis Pilaris Atrophicans Keratosis pilaris atrophicans (KPA) is a rare form of keratosis pilaris, a skin condition that affects around 50-80% of the world’s population. It is a chronic, hereditary skin disease that causes scaly, bumpy skin and hair loss. The condition is most commonly found on the upper arms, legs, and cheeks, and it is usually diagnosed […]...
  5. Benign Mucosal Pemphigoid Benign mucosal pemphigoid, also known as cicatricial pemphigoid, is a rare autoimmune disease that affects the mucous membranes of the body. It is characterized by the formation of blisters and erosions on the mucosal surfaces, such as the mouth, eyes, and genital area. The disease is considered benign because it does not spread to other […]...
  6. Endemic Pemphigus Foliaceus (EPF) Endemic pemphigus foliaceus (EPF) is a rare autoimmune skin disease characterized by chronic and recurrent eruptions of blistering, scaling and crusting skin lesions. It is also known as fogo selvagem or wildfire. EPF is endemic or restricted to specific geographic areas, typically in rural regions of South America, Africa, and the Middle East. The disease […]...
  7. Transient Acantholytic Dermatosis (TAD) Transient acantholytic dermatosis (TAD) is a skin condition characterized by the formation of blisters and erosions on the skin that can be itchy and painful. The word “transient” refers to the temporary nature of the condition, while “acantholytic” refers to the loss of the protective outer layer of skin cells. The “dermatosis” part of the […]...
  8. Persistent Acantholytic Dermatosis Persistent acantholytic dermatosis is a rare skin condition that is characterized by the formation of persistent, irregularly shaped blisters or erosions on the skin. The blisters are caused by a breakdown in the cohesion of the skin cells, leading to a separation of the cells and the formation of fluid-filled spaces. This condition is often […]...
  9. Subacute migratory panniculitis Subacute migratory panniculitis of Vilanova, also known as migratory panniculitis of Vilanova, is a rare skin condition that was first described by Spanish dermatologist Dr. Josep Vilanova in 1960. It is characterized by the sudden appearance of painful, red, and tender nodules or subcutaneous nodules that appear mainly on the legs, but can also affect […]...
  10. Acrokeratosis Paraneoplastica Acrokeratosis paraneoplastica, also known as Bazex syndrome, is a skin disorder that is associated with internal malignancies, particularly those affecting the digestive system. It is characterized by the presence of scaly patches and thickened skin on the fingertips, toes, and the nail beds. The condition is considered to be a cutaneous manifestation of underlying cancer, […]...

To Get Daily Health Newsletter

We don’t spam! Read our privacy policy for more info.

Terms and Conditions of Use
Privacy Policy
Cookie Policy
Editorial Policy
Advertising Policy
EU User Consent Policy
Correction Policy
Citation Policy
Ethics and Logical Policies
About Us
Contact Us
Newsletter
Career
Sitemap
Advertise with us
Editorial Board Members
Review Board Member
Team RxHarun
Web Developers Team
Guest Posts and Sponsored Posts
Request for Board Member
Women Writers
Download Mobile Apps
Follow us on Social Media
© 2012 - 2025; All rights reserved by authors. Powered by Mediarx International LTD, a subsidiary company of Rx Foundation.
RxHarun
Logo