Herniated Cervical Intervertebral Disc Between C4 – C5

A herniated cervical intervertebral disc between C4 and C5, often called a “slipped” or “ruptured” disc at the C4–C5 level, occurs when the inner gel-like core (nucleus pulposus) pushes through a tear in the tougher outer ring (annulus fibrosus) and may press on nearby nerves or the spinal cord. Though less common than herniations at lower cervical levels, C4–C5 herniation can still cause significant neck pain, arm weakness, and sensory changes Herniated DiscWebMD.


Anatomy of the C4–C5 Intervertebral Disc

Structure & Composition
Each intervertebral disc is a fibrocartilaginous joint composed of:

  • Annulus fibrosus: concentric layers of tough collagen fibers that contain and support the disc under pressure.

  • Nucleus pulposus: a hydrated, gelatinous core rich in proteoglycans that absorbs shock.

  • Cartilaginous endplates: thin hyaline cartilage layers that interface with the vertebral bodies, allowing nutrient exchange KenhubRadiopaedia.

Location

The C4–C5 disc sits between the fourth (C4) and fifth (C5) cervical vertebrae in the mid-neck, an area that permits forward, backward, and rotational movements Deuk Spine.

Origin & Insertion

Functionally, the disc “originates” at the inferior endplate of C4 and “inserts” onto the superior endplate of C5 through its cartilaginous endplates, anchoring it securely between the vertebrae Radiopaedia.

Blood Supply

Intervertebral discs are largely avascular; they rely on diffusion of nutrients and oxygen from capillaries in the adjacent vertebral endplates and surrounding vertebral bodies Kenhub.

Nerve Supply

Sensory fibers from the sinuvertebral (recurrent meningeal) nerves innervate the outer annulus and posterior longitudinal ligament, relaying pain sensations when the disc is stressed or injured TeachMe Orthopedics.

Functions

  1. Shock absorption: cushions forces from head and neck movements.

  2. Load distribution: spreads compressive loads evenly across vertebrae.

  3. Flexibility: allows flexion, extension, lateral bending, and rotation of the neck.

  4. Height maintenance: preserves intervertebral spacing and foraminal size for nerve roots.

  5. Spinal alignment: contributes to the natural cervical lordosis (inward curve).

  6. Protection: shields spinal cord and exiting nerve roots from direct vertebral pressure Spine InfoRadiopaedia.


Types of C4–C5 Disc Herniation

Disc herniations are classified by how much and where disc material protrudes:

  1. Bulging Disc: the annulus fibrosus balloons outward without tearing.

  2. Protrusion: inner nucleus pushes against intact annular fibers, creating a localized bulge.

  3. Extrusion: nucleus pulposus breaks through a tear but remains connected to the disc.

  4. Sequestration: a fragment of the nucleus separates and may migrate in the spinal canal.

They may also be described by location relative to the spinal canal:

Central, paracentral, foraminal, or extraforaminal herniations Verywell Healthphysiosunit.com.


Causes (Risk Factors)

  1. Age-related degeneration (disc dehydration and loss of elasticity) Clínic BarcelonaMayo Clinic

  2. Genetic predisposition to weak collagen fibers Mayo Clinic

  3. Smoking (impairs disc nutrition) Mayo Clinic

  4. Obesity (increases axial loading) Verywell Health

  5. Poor posture (forward head tilt adds stress) Clínic Barcelona

  6. Sedentary lifestyle (weak neck musculature) Clínic Barcelona

  7. Repetitive lifting or twisting (occupational hazards) Mayo Clinic

  8. Traumatic injury (falls, whiplash) Mayo Clinic

  9. Heavy manual labor (chronic overload) Riverside Health

  10. Vibration exposure (e.g., heavy machinery) Riverside Health

  11. High-impact sports (football tackles, gymnastics) Riverside Health

  12. Prolonged computer use (neck flexion) Riverside Health

  13. Radiation exposure (degenerative changes) Health tech for the digital age

  14. Steroid use (weakens disc structures) Health tech for the digital age

  15. Diabetes (microvascular damage to endplates) Riverside Health

  16. Connective tissue disorders (e.g., Ehlers–Danlos) Mayo Clinic

  17. Poor nutrition (inadequate building blocks for disc repair) Riverside Health

  18. Dehydration (reduces disc turgor) Clínic Barcelona

  19. Occupational driving (whole-body vibration) Riverside Health

  20. Previous disc herniation elsewhere (higher risk at other levels) Riverside Health.

Symptoms

  1. Neck pain (often sharp or throbbing) WebMD

  2. Stiffness reducing neck motion Acibadem HealthPoint

  3. Shoulder or scapular pain Spine-health

  4. Radicular arm pain following the C5 dermatome Spine-health

  5. Numbness or tingling in shoulder, arm, or hand WebMD

  6. Muscle weakness in the deltoid or biceps Spine-health

  7. Decreased reflexes (biceps reflex) Spine-health

  8. Muscle spasms in the neck and shoulder girdle Acibadem HealthPoint

  9. Occipital headaches Acibadem HealthPoint

  10. Loss of fine motor skills (difficulty with buttons) WebMD

  11. Balance issues (if spinal cord compressed) WebMD

  12. Lhermitte’s sign (electric shock sensation on neck flexion) Merck Manuals

  13. Hoffmann’s sign (finger flexion on flicking finger) Merck Manuals

  14. Gait disturbance (in severe myelopathy) WebMD

  15. Loss of bladder or bowel control (rare, emergency) WebMD

  16. Pain aggravated by coughing or sneezing Spine-health

  17. Night pain waking from sleep Acibadem HealthPoint

  18. Clumsiness dropping objects WebMD

  19. Muscle atrophy in chronic cases WebMD

  20. Cold intolerance in affected limb Spine-health.


Diagnostic Tests

  1. Patient history (onset, activities, prior neck issues) Spine-health

  2. Physical examination (palpation, range of motion) Spine-health

  3. Neurological exam (strength, sensation, reflexes) Merck Manuals

  4. Spurling’s test (neck extension + axial load provoking radicular pain) Barricaid Blog

  5. Lhermitte’s sign (shooting pain with neck flexion) Merck Manuals

  6. Hoffmann’s sign (thumb flexion test) Merck Manuals

  7. X-rays (rule out fracture, alignment, degenerative changes) Clínic Barcelona

  8. MRI (gold standard to visualize disc and nerve compression) neurosurgery.weillcornell.orgMayo Clinic

  9. CT scan (osseous detail, when MRI contraindicated) neurosurgery.weillcornell.orgClínic Barcelona

  10. CT myelogram (contrast-enhanced imaging for nerve root compression) Mayo Clinic

  11. Electromyography (EMG) (nerve conduction delays) Mayo Clinic

  12. Nerve conduction studies (quantify nerve root involvement) Mayo Clinic

  13. Discography (provocative injection reproducing pain) neurosurgery.weillcornell.org

  14. Bone scan (rule out infection, fracture) neurosurgery.weillcornell.org

  15. Ultrasound (for soft-tissue guidance) neurosurgery.weillcornell.org

  16. Provocative maneuvers (e.g., shoulder abduction relief sign) Spine-health

  17. Cervical traction trial (if symptom relief occurs, suggests discogenic pain) neurosurgery.weillcornell.org

  18. Functional fluoroscopy (dynamic assessment of instability) neurosurgery.weillcornell.org

  19. Laboratory tests (rule out inflammatory or infectious causes) Merck Manuals

  20. Pulmonary function tests (if respiratory compromise suspected in high cervical cord compression) neurosurgery.weillcornell.org.


Non-Pharmacological Treatments

  1. Rest (short-term activity modification) Spine-health

  2. Ice therapy (reduce inflammation) Spine-health

  3. Heat therapy (muscle relaxation) Spine-health

  4. Physical therapy (strength, flexibility) Spine-health

  5. McKenzie exercises (directional preference) The Spine Institute CSR

  6. Isometric neck exercises Verywell Health

  7. Cervical traction (mechanical or manual) Verywell Health

  8. Soft cervical collar (short-term support) Spine-health

  9. Transcutaneous electrical nerve stimulation (TENS) Spine-health

  10. Massage therapy (trigger point release) Spine-health

  11. Acupuncture Spine-health

  12. Ultrasound therapy The Spine Institute CSR

  13. Spinal manipulation (chiropractic)

  14. Yoga (neck-friendly poses) Verywell Health

  15. Pilates (core stabilization) Verywell Health

  16. Aquatic therapy Verywell Health

  17. Inversion therapy Verywell Health

  18. Alexander Technique Cervical Herniated Disc

  19. Posture retraining Spine and Pain Clinics of North America

  20. Ergonomic adjustments (workstation setup) Spine and Pain Clinics of North America

  21. Core strengthening (abdominals, back extensors) Verywell Health

  22. Weight management Verywell Health

  23. Psychological counseling (coping strategies) Cervical Herniated Disc

  24. Biofeedback Wikipedia

  25. Kinesio taping Cervical Herniated Disc

  26. Occupational therapy (adaptive techniques) The Spine Institute CSR

  27. Sleep position modification (neck support pillows) Cervical Herniated Disc

  28. Mindfulness meditation Spine-health

  29. Nutritional counseling (anti-inflammatory diet) Riverside Health

  30. Education (ergonomics, body mechanics) Spine-health.


Drug Treatments

  1. Acetaminophen (Tylenol) – mild analgesic for neck pain axionspine.com

  2. Ibuprofen (Advil) – NSAID to reduce pain and inflammation HealthCentral

  3. Naproxen (Aleve) – longer-acting NSAID HealthCentral

  4. Aspirin – anti-inflammatory and analgesic

  5. Diclofenac – prescription NSAID for moderate pain

  6. Celecoxib (Celebrex) – COX-2 inhibitor with fewer GI side effects

  7. Meloxicam – NSAID with once-daily dosing

  8. Indomethacin – potent NSAID for acute flare-ups

  9. Ketorolac – injectable NSAID for severe pain

  10. Cyclobenzaprine (Flexeril) – muscle relaxant for spasms Dr. Kevin Pauza

  11. Baclofen – spasticity-targeted muscle relaxant

  12. Tizanidine – short-acting spasmolytic

  13. Methocarbamol – central muscle relaxant

  14. Carisoprodol (Soma) – muscle relaxant for acute spasm

  15. Gabapentin (Neurontin) – neuropathic pain agent Medscape

  16. Pregabalin (Lyrica) – pain modulator for nerve root irritation

  17. Amitriptyline – TCA for chronic radicular pain

  18. Duloxetine (Cymbalta) – SNRI for neuropathic components

  19. Tramadol – weak opioid for moderate to severe pain axionspine.com

  20. Prednisone – short-course oral steroid to reduce nerve root inflammation Spine-health.


Surgical Options

  1. Anterior Cervical Discectomy and Fusion (ACDF) – remove disc and fuse C4–C5 David Barnett MDCleveland Clinic

  2. Anterior Cervical Disc Arthroplasty (Disc Replacement) – remove and replace with artificial disc Verywell Health

  3. Posterior Cervical Foraminotomy – enlarge nerve exit canal via posterior approach Spine-health

  4. Posterior Cervical Discectomy – remove herniated fragment from back of spine Spine-health

  5. Laminoplasty – hinge opening of lamina to decompress spinal cord

  6. Laminectomy – remove lamina to relieve cord compression

  7. Corpectomy – remove vertebral body and adjacent discs for multilevel decompression

  8. Microendoscopic Discectomy – minimally invasive disc removal

  9. Endoscopic Anterior Discectomy – small-portal front approach

  10. Spinal fusion with instrumentation – stabilize multiple levels David Barnett MD.


Prevention Strategies

  1. Maintain good posture – neutral cervical alignment Spine and Pain Clinics of North America

  2. Ergonomic workspace – monitor at eye level, supportive chair Spine and Pain Clinics of North America

  3. Regular exercise – strengthen neck and core Verywell Health

  4. Use proper lifting techniques – bend hips/knees, not back Spine and Pain Clinics of North America

  5. Weight management – reduce disc loading Verywell Health

  6. Quit smoking – improve disc nutrition Mayo Clinic

  7. Stay hydrated – maintain disc water content Clínic Barcelona

  8. Stretch before activity – prepare soft tissues Verywell Health

  9. Use a supportive pillow – cervical contour to support neck

  10. Take frequent breaks – avoid prolonged static neck positions Spine and Pain Clinics of North America.


When to See a Doctor

  • Severe or worsening pain lasting >6 weeks despite treatment.

  • Progressive neurological deficits (weakness, numbness).

  • Loss of bowel/bladder control (emergency).

  • Signs of spinal cord compression (balance problems, gait changes).

  • Acute severe trauma to the neck.

  • Red-flag symptoms like fever (infection) or unexplained weight loss (tumor) WebMDMerck Manuals.


Frequently Asked Questions

  1. What causes a C4–C5 disc herniation?
    Wear-and-tear degeneration, poor posture, sudden trauma, or repetitive stress can weaken the annulus fibrosus, allowing the nucleus pulposus to herniate at C4–C5 Clínic BarcelonaMayo Clinic.

  2. How is a C4–C5 herniated disc diagnosed?
    Through patient history, physical exam (Spurling’s test, neurological assessment), and imaging—especially MRI, which clearly shows disc and nerve involvement neurosurgery.weillcornell.orgMayo Clinic.

  3. Can a herniated C4–C5 disc heal on its own?
    Yes—many improve with conservative care (physical therapy, rest) over 4–6 weeks as inflammation subsides and the disc resorbs partially Spine-health.

  4. What exercises help a C4–C5 disc herniation?
    McKenzie extension exercises, gentle isometrics, cervical retractions, and core stabilization are often prescribed to unload the disc and strengthen supporting muscles Verywell Health.

  5. When is surgery necessary?
    Surgery is considered if there is progressive neurological loss, intractable pain despite 6–12 weeks of conservative care, or acute spinal cord compression Verywell Health.

  6. What is ACDF?
    Anterior Cervical Discectomy and Fusion involves removing the herniated disc via a front-of-neck incision and fusing C4–C5 with a bone graft or cage to stabilize the spine Cleveland Clinic.

  7. What are the risks of cervical disc surgery?
    Potential risks include infection, nerve injury, swallowing difficulties, non-union (failed fusion), and adjacent-level degeneration Cleveland Clinic.

  8. How long is recovery after ACDF?
    Most patients wear a soft collar briefly and can resume light activities in days; full fusion and return to normal activities take 6–12 weeks Verywell Health.

  9. Are there alternatives to fusion?
    Yes—cervical disc arthroplasty (artificial disc replacement) preserves motion and may reduce adjacent-level stress Verywell Health.

  10. What medications relieve C4–C5 herniation pain?
    NSAIDs, muscle relaxants, neuropathic agents (gabapentin), short-term opioids, and corticosteroids as needed for flare-ups HealthCentralMedscape.

  11. Is rest always recommended?
    Short-term rest (1–2 days) can ease acute pain, but prolonged inactivity risks muscle weakening; gradual return to activity is best Spine-health.

  12. Can posture correction prevent recurrence?
    Yes—maintaining neutral neck alignment at work and during activities reduces disc stress and recurrence risk Spine and Pain Clinics of North America.

  13. What is the difference between a bulging and herniated disc?
    A bulge involves symmetric outward expansion of the annulus without tearing, while herniation implies a focal tear through which nucleus material extrudes Verywell Health.

  14. How do I sleep with a disc herniation?
    Use a cervical contour pillow and sleep on your back or side with moderate pillow support under the neck Cervical Herniated Disc.

  15. Can weight loss help?
    Reducing excess body weight decreases axial loads on cervical discs, thereby lowering herniation risk and aiding recovery Verywell Health.

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.

The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members

Last Updated: April 28, 2025.

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