Asymmetric thecal sac indentation refers to a condition seen on spinal imaging—most often magnetic resonance imaging (MRI)—where the normally smooth, oval-shaped sac surrounding the spinal cord (the thecal sac) appears pressed in more on one side than the other. This “dent” or “effacement” happens when nearby structures, such as a herniated disc or an overgrown facet joint, push against the dural sac unevenly, creating a characteristic asymmetric impression on its outline. In many cases, mild asymmetry causes no symptoms, but when the pressure is significant, it can impinge nerve roots or the spinal cord itself, leading to pain, numbness, or weakness in the limbs Spine Info.
Anatomy of the Thecal Sac
Structure & Location:
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The thecal sac is the membranous sheath of dura mater that encases the spinal cord, nerve roots, and cerebrospinal fluid (CSF). It extends from the base of the skull (foramen magnum) down through the spinal canal to approximately the S2 vertebral level Deuk Spine.
Origin & “Insertion”:
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Origin: Continues directly from the cranial dura mater at the foramen magnum.
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Distal End (“Insertion”): Narrows and tapers at the sacral canal, ending near the S2 level. Although not a muscle, this terminology helps picture its span.
Blood Supply:
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Supplied segmentally by radicular branches of the vertebral, intercostal, lumbar, and sacral arteries. These small meningeal arteries penetrate the dura to nourish its layers ChiroGeek.
Nerve Supply:
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Innervated by recurrent meningeal (sinuvertebral) nerves, which branch off the spinal nerves to supply the dura and posterior longitudinal ligament.
Key Functions:
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Protection: Acts as a tough barrier guarding the spinal cord and nerve roots from mechanical injury.
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CSF Containment: Forms a sealed chamber for cerebrospinal fluid, which cushions neural tissue.
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Shock Absorption: Distributes forces evenly along the canal when under load.
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Nutrient Transport: CSF within the sac carries oxygen and nutrients to nerve tissues.
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Waste Removal: CSF flow helps clear metabolic byproducts from the central nervous system.
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Buoyancy: Provides a low-friction environment that reduces the effective weight of the spinal cord.
Types of Asymmetric Thecal Sac Indentation
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Disc Herniation–Induced: Protruding nucleus pulposus pressing eccentrically on the dura.
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Facet Joint Hypertrophy–Induced: Overgrown facet joints encroach from one side.
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Ligamentum Flavum Hypertrophy–Induced: Thickening of ligamentum flavum unevenly narrowing the canal.
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Synovial Cyst–Induced: Fluid-filled cysts from facet joints.
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Epidural Lipomatosis–Induced: Excess fat deposition more on one side.
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Osteophyte–Induced: Bony spurs from degenerative changes.
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Tumor–Induced: Asymmetric mass effect from benign or malignant growths.
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Abscess–Induced: Localized infection with pus exerting pressure.
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Hematoma–Induced: Blood collection in the epidural space.
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Congenital Stenosis–Induced: Developmental narrowing more pronounced unilaterally.
Common Causes
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Lumbar disc herniation Spine Info
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Cervical disc protrusion Medscape
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Facet joint osteoarthritis
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Ligamentum flavum thickening
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Synovial cyst formation
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Epidural lipomatosis
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Vertebral osteophytes Radiopaedia
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Spinal tumors (e.g., meningioma)
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Epidural abscess
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Spinal epidural hematoma
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Spondylolisthesis
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Degenerative spondylosis
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Rheumatoid arthritis–related pannus
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Paget disease of bone
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Ankylosing spondylitis
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Discitis (infection)
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Tarlov cysts Deuk Spine
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Traumatic vertebral fracture
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Postsurgical scar tissue
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Congenital dural ectasia Radsource
Possible Symptoms
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Localized back or neck pain
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Radicular pain (shooting pain along a nerve)
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Numbness in an arm or leg
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Tingling (“pins and needles”)
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Muscle weakness
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Difficulty walking
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Imbalance or unsteady gait
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Reflex changes (hyperreflexia or hyporeflexia)
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Sciatica-like leg pain
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Shoulder or arm radiculopathy
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Muscle cramps
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Fatigue due to chronic pain
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Bladder dysfunction (in severe cases)
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Bowel dysfunction (in severe cases)
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Sexual dysfunction
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Loss of fine motor skills
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Coldness or heaviness in limbs
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Gait claudication (pain when walking)
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Postural intolerance
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Sensory loss in a dermatome
Diagnostic Tests
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MRI Scan: Gold standard for soft-tissue evaluation Spine Info
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CT Scan: Especially with myelography for bony detail Medscape
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CT Myelogram
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Conventional Myelography
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X-rays (Flexion/Extension views)
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Bone Scan
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Electromyography (EMG)
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Nerve Conduction Studies (NCS)
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Somatosensory Evoked Potentials (SSEP)
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Blood tests (CBC, ESR, CRP for infection/inflammation)
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CSF Analysis (if infection suspected)
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Discography
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Ultrasound (for superficial lesions)
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CT-guided biopsy (for tumors/abscess)
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Dynamic MRI
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Spinal angiography (rare)
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Positron Emission Tomography (PET)
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Neurological exam
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Physical exam tests (e.g., straight leg raise)
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Facet joint block (diagnostic and therapeutic)
Non-Pharmacological Treatments
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Physical therapy with guided exercises
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Core strengthening exercises
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Stretching routines
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Spinal traction
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Heat therapy (warm packs)
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Cold therapy (ice packs)
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Transcutaneous electrical nerve stimulation (TENS)
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Massage therapy
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Acupuncture Spine Info
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Chiropractic adjustments
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Yoga
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Pilates
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Ergonomic workspace setup
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Posture training
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Weight loss programs
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Swimming or aquatic therapy
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Mindfulness meditation
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Cognitive-behavioral therapy (CBT)
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Biofeedback
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Brace or corset support
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Dietary modifications (anti-inflammatory diet)
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Smoking cessation
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Gait training
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Education on body mechanics
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Kinesio taping
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Activity modification
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Prolotherapy injections
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Spinal decompression devices
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Vibration therapy
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Nutritional supplements (vitamin D, calcium)
Commonly Used Drugs
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NSAIDs (ibuprofen, naproxen)
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Acetaminophen
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Opioid analgesics (short-term only)
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Muscle relaxants (cyclobenzaprine)
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Oral corticosteroids
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Epidural steroid injections
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Gabapentin
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Pregabalin
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Duloxetine
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Amitriptyline
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Tramadol
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Topical NSAID gels
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Lidocaine patches
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Capsaicin cream
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Bisphosphonates (if bone-related)
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DMARDs (for rheumatoid causes)
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Antibiotics (if infection)
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Antifungals (rare)
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Calcitonin (for vertebral compression)
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Biologics (TNF inhibitors for ankylosing spondylitis)
Surgical Options
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Microdiscectomy (removal of herniated disc fragment)
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Laminectomy (removal of part of the vertebral arch)
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Foraminotomy (widening the nerve exit)
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Laminoplasty (reconstructing the lamina)
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Spinal fusion (stabilizing vertebrae)
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Facet joint resection
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Endoscopic spine surgery
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Disk arthroplasty (disc replacement)
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Vertebroplasty/Kyphoplasty (for compression fractures)
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Decompression with instrumentation
Prevention Strategies
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Maintain a healthy weight
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Practice core-strengthening exercises
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Use proper lifting techniques
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Adopt ergonomic workstations
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Take regular movement breaks
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Quit smoking
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Follow an anti-inflammatory diet
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Stay well-hydrated
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Wear supportive footwear
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Get periodic spinal check-ups if at high risk
When to See a Doctor
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Severe, unrelenting pain that does not improve with rest
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Progressive muscle weakness or gait changes
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New bladder or bowel dysfunction
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Loss of sensation in the genital or buttock area
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Signs of infection (fever, chills)
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History of cancer or unexplained weight loss
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Sudden onset after trauma
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Symptoms interfering with daily activities
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Pain radiating below the knee or into the arm
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No improvement after six weeks of conservative care
Frequently Asked Questions
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What exactly causes the thecal sac to indent?
Often a herniated disc, bone spur, or thickened ligament pushes against the dura mater Spine Info. -
Is asymmetric indentation always painful?
No—mild cases can be painless if nerve roots aren’t compressed PMC. -
How is this different from central thecal sac compression?
Central compression pushes evenly from both sides, while asymmetric affects one side more. -
Can physical therapy reverse the indentation?
Therapy reduces inflammation and strengthens muscles but does not change the underlying indentation. -
When are injections recommended?
If conservative measures fail after six weeks and imaging shows nerve irritation. -
What are the risks of surgery?
Potential risks include infection, nerve damage, and spinal instability. -
How long is recovery after laminectomy?
Typically 4–6 weeks for basic activities; full recovery can take 3–6 months. -
Will my symptoms return after treatment?
Proper prevention and lifestyle changes minimize the risk of recurrence. -
Is MRI safe for everyone?
Contraindications include certain metal implants and pacemakers. -
Are there non-surgical ways to “pad” the thecal sac?
Not directly—treatments focus on removing or reducing the pressing source. -
How does a synovial cyst cause indentation?
Cysts form on facet joints and bulge into the canal on one side PMC. -
Can children get thecal sac indentation?
Rare, usually from congenital anomalies or trauma. -
How does bone density affect this condition?
Lower bone density can worsen fractures that indent the sac. -
What role does posture play?
Poor posture increases stress on spinal structures, accelerating degeneration. -
Is walking or swimming better for recovery?
Swimming offers low-impact support and is often recommended.
Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.
The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members
Last Updated: May 02, 2025.