Internal Iliac Artery Tumors

Internal iliac artery tumors are abnormal growths that occur in the blood vessels supplying the pelvic region. These tumors can pose serious health risks, but understanding their types, causes, symptoms, diagnostic tests, and treatment options is crucial for effective management. In this comprehensive guide, we will break down complex medical information into simple, plain English to enhance readability, visibility, and accessibility for everyone.

Types of Internal Iliac Artery Tumors:

  1. Hemangioma:
    • Description: Hemangiomas are non-cancerous growths formed from an excess of blood vessels in the internal iliac artery.
    • Defination: A hemangioma is a benign tumor that results from an abnormal clustering of blood vessels.
  2. Angiosarcoma:
    • Description: Angiosarcomas are malignant tumors originating from the blood vessels in the internal iliac artery.
    • Definition: Angiosarcoma is a cancerous growth that develops in the blood vessels, posing a more severe threat.

Causes of Internal Iliac Artery Tumors:

  1. Genetic Predisposition:
    • Some individuals may inherit a genetic predisposition to develop internal iliac artery tumors.
  2. Chronic Inflammation:
    • Prolonged inflammation in the pelvic region may contribute to the formation of these tumors.
  3. Radiation Exposure:
    • Previous exposure to radiation therapy in the pelvic area increases the risk of internal iliac artery tumors.
  4. Hormonal Changes:
    • Fluctuations in hormone levels, especially during pregnancy, may play a role in tumor development.
  5. Age:
    • Advancing age is a risk factor, as the likelihood of tumor growth increases with age.
  6. Smoking:
    • Tobacco smoke contains carcinogens that can contribute to the development of tumors.
  7. Prior Pelvic Surgery:
    • Previous pelvic surgeries may trigger abnormal cell growth in the internal iliac artery.
  8. Chronic Infections:
    • Prolonged infections in the pelvic region may lead to the formation of tumors.
  9. Immune System Compromise:
    • Weakened immune systems may struggle to control abnormal cell growth.
  10. Obesity:
    • Excess body weight is associated with an increased risk of developing internal iliac artery tumors.
  11. Hormone Replacement Therapy:
    • Long-term use of hormone replacement therapy may influence tumor formation.
  12. High Blood Pressure:
    • Uncontrolled hypertension can contribute to the development of these tumors.
  13. Diabetes:
    • Poorly managed diabetes may be linked to an elevated risk of internal iliac artery tumors.
  14. Chronic Kidney Disease:
    • Impaired kidney function may impact the body’s ability to regulate cell growth.
  15. Environmental Toxins:
    • Exposure to certain environmental toxins may contribute to tumor development.
  16. Chronic Pelvic Pain:
    • Persistent pelvic pain may be associated with an increased risk of internal iliac artery tumors.
  17. Blood Vessel Disorders:
    • Conditions affecting blood vessels, such as aneurysms, may contribute to tumor growth.
  18. Inflammatory Bowel Disease:
    • Chronic inflammation in the gastrointestinal tract may influence tumor formation.
  19. Previous Cancer Treatment:
    • Individuals who have undergone cancer treatments may be at a higher risk of developing internal iliac artery tumors.
  20. Viral Infections:
    • Certain viruses may play a role in triggering abnormal cell growth in the pelvic region.

Symptoms of Internal Iliac Artery Tumors:

  1. Pelvic Pain:
    • Dull or sharp pain in the pelvic region may indicate the presence of tumors.
  2. Leg Swelling:
    • Tumors can obstruct blood flow, leading to swelling in the legs.
  3. Lower Back Pain:
    • Discomfort in the lower back may be a symptom of internal iliac artery tumors.
  4. Changes in Bowel Habits:
    • Tumors can exert pressure on surrounding organs, causing alterations in bowel movements.
  5. Hematuria:
    • Blood in the urine may be a sign of tumor-related complications.
  6. Abdominal Mass:
    • A palpable mass in the abdominal area could be indicative of tumor growth.
  7. Erectile Dysfunction:
    • Tumors affecting blood flow may contribute to erectile dysfunction in men.
  8. Irregular Menstrual Cycles:
    • Women may experience changes in menstrual patterns due to hormonal imbalances caused by tumors.
  9. Pelvic Pressure:
    • Feeling of heaviness or pressure in the pelvic area may be associated with tumor growth.
  10. Fatigue:
    • Tumors can lead to anemia, resulting in fatigue and weakness.
  11. Frequent Urination:
    • Tumors pressing on the bladder can cause an increased urge to urinate.
  12. Constipation:
    • Obstruction of the intestines by tumors may lead to constipation.
  13. Nausea and Vomiting:
    • Tumors affecting digestive organs may cause nausea and vomiting.
  14. Unexplained Weight Loss:
    • Rapid weight loss without an apparent cause may be a symptom of internal iliac artery tumors.
  15. Painful Intercourse:
    • Tumors in the pelvic region can cause discomfort during sexual activity.
  16. Fever:
    • Infections associated with tumors may lead to fever.
  17. Changes in Urine Color:
    • Tumor-related issues may cause changes in the color of urine.
  18. Difficulty Walking:
    • Impaired blood flow to the legs can result in difficulty walking.
  19. Abdominal Bloating:
    • Tumors may cause abdominal swelling and bloating.
  20. High Blood Pressure:
    • Tumors affecting blood vessels can lead to hypertension.

Diagnostic Tests for Internal Iliac Artery Tumors:

  1. MRI (Magnetic Resonance Imaging):
    • Description: A non-invasive imaging test that uses magnetic fields to create detailed images of the pelvic region.
    • Purpose: To visualize the internal iliac artery and detect any abnormalities or tumors.
  2. CT Scan (Computed Tomography):
    • Description: X-ray technology combined with computer processing to create cross-sectional images of the pelvic area.
    • Purpose: To identify and evaluate internal iliac artery tumors with high precision.
  3. Ultrasound:
    • Description: High-frequency sound waves create images of the internal structures, allowing for tumor detection.
    • Purpose: To assess blood flow and identify abnormalities in the internal iliac artery.
  4. Angiography:
    • Description: A contrast dye is injected into the blood vessels, making them visible on X-rays.
    • Purpose: To visualize blood flow and detect any blockages or abnormalities in the internal iliac artery.
  5. Biopsy:
    • Description: Tissue samples are collected from the tumor for examination under a microscope.
    • Purpose: To determine if the tumor is benign or malignant.
  6. Blood Tests:
    • Description: Analysis of blood samples to check for markers indicative of tumor presence.
    • Purpose: To identify any abnormalities that may

Treatments for Internal Iliac Artery Tumors:

  1. Surgery: Removing the tumor to eliminate the threat.
  2. Radiation therapy: Using targeted radiation to shrink or destroy tumors.
  3. Chemotherapy: Medications to kill or slow the growth of cancer cells.
  4. Embolization: Blocking blood flow to the tumor to reduce its size.
  5. Immunotherapy: Boosting the immune system to fight cancer cells.

Drugs Used in Internal Iliac Artery Tumor Treatment:

  1. Doxorubicin: A chemotherapy drug inhibiting cancer cell growth.
  2. Ifosfamide: Used in combination with other drugs for enhanced effectiveness.
  3. Pazopanib: Targets specific pathways to inhibit tumor growth.
  4. Gemcitabine: Disrupts the cell division process in cancer cells.
  5. Trabectedin: Affects the DNA repair process in cancer cells.

Surgery Options for Internal Iliac Artery Tumors:

  1. Tumor resection: Removing the tumor to prevent further growth.
  2. Artery reconstruction: Restoring blood flow through surgical techniques.
  3. Endovascular procedures: Minimally invasive techniques using catheters and stents.
  4. Bypass surgery: Redirecting blood flow around the tumor-affected area.
  5. Pelvic exenteration: Extensive surgery removing pelvic organs affected by the tumor.

Conclusion:

Understanding internal iliac artery tumors involves recognizing the types, causes, symptoms, diagnostic tests, and treatment options. While surgery, chemotherapy, and radiation therapy are common approaches, advancements in targeted drugs and immunotherapy are shaping new possibilities for managing these tumors. Early detection through regular check-ups and awareness of potential symptoms is crucial for timely intervention. This article aims to simplify the complexities of internal iliac artery tumors, making the information more accessible and comprehensible for a wider audience

 

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.

  1. https://www.ncbi.nlm.nih.gov/books/NBK532297/
  2. https://www.ncbi.nlm.nih.gov/books/NBK549894/
  3. https://www.ncbi.nlm.nih.gov/books/NBK526002/
  4. https://www.ncbi.nlm.nih.gov/books/NBK538474/
  5. https://www.ncbi.nlm.nih.gov/books/NBK53086/
  6. https://www.ncbi.nlm.nih.gov/books/NBK470237/
  7. https://www.ncbi.nlm.nih.gov/books/NBK576402/
  8. https://www.ncbi.nlm.nih.gov/books/NBK525964/
  9. https://www.ncbi.nlm.nih.gov/books/NBK441963/
  10. https://medlineplus.gov/skinconditions.html
  11. https://www.aad.org/about/burden-of-skin-disease
  12. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  13. https://www.cdc.gov/niosh/topics/skin/default.html
  14. https://www.skincancer.org/
  15. https://illnesshacker.com/
  16. https://endinglines.com/
  17. https://www.jaad.org/
  18. https://www.psoriasis.org/about-psoriasis/
  19. https://books.google.com/books?
  20. https://www.niams.nih.gov/health-topics/skin-diseases
  21. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  22. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
  23. https://dermnetnz.org/topics
  24. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  25. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
  26. https://aafa.org/allergies/allergy-symptoms/skin-allergies/
  27. https://www.nibib.nih.gov/
  28. https://rxharun.com/rxharun/rxharun/article-types/skin-care-beauty/skin-diseases-types-symptoms-treatment/
  29. https://www.nei.nih.gov/
  30. https://en.wikipedia.org/wiki/List_of_skin_conditions
  31. https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
  32. https://en.wikipedia.org/wiki/Skin_condition
  33. https://oxfordtreatment.com/
  34. https://www.nidcd.nih.gov/health/
  35. https://consumer.ftc.gov/articles/w
  36. https://www.nccih.nih.gov/health
  37. https://catalog.ninds.nih.gov/
  38. https://www.aarda.org/diseaselist/
  39. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
  40. https://www.nibib.nih.gov/
  41. https://www.nia.nih.gov/health/topics
  42. https://www.nichd.nih.gov/
  43. https://www.nimh.nih.gov/health/topics
  44. https://www.nichd.nih.gov/
  45. https://www.niehs.nih.gov
  46. https://www.nimhd.nih.gov/
  47. https://www.nhlbi.nih.gov/health-topics
  48. https://obssr.od.nih.gov/
  49. https://www.nichd.nih.gov/health/topics
  50. https://rarediseases.info.nih.gov/diseases
  51. https://beta.rarediseases.info.nih.gov/diseases
  52. https://orwh.od.nih.gov/

References