Circumflex Artery Regurgitation

Circumflex artery regurgitation is a condition where the flow of blood backward in the heart’s circumflex artery is compromised, leading to various symptoms and complications. In this guide, we’ll explore the types, causes, symptoms, diagnostic tests, treatments, drugs, and surgeries associated with this condition in simple, easy-to-understand language.

Types of Circumflex Artery Regurgitation:

  1. Acute Circumflex Artery Regurgitation
  2. Chronic Circumflex Artery Regurgitation

Causes of Circumflex Artery Regurgitation:

  1. Coronary artery disease
  2. Rheumatic heart disease
  3. Infective endocarditis
  4. Myocardial infarction (heart attack)
  5. Cardiomyopathy
  6. Mitral valve prolapse
  7. Congenital heart defects
  8. Endocardial cushion defect
  9. Trauma to the chest
  10. Hypertension
  11. Aortic dissection
  12. Aortic valve disease
  13. Hypertrophic cardiomyopathy
  14. Marfan syndrome
  15. Ankylosing spondylitis
  16. Connective tissue disorders
  17. Bacterial infections
  18. Autoimmune diseases
  19. Medications that affect heart function
  20. Age-related degeneration of heart valves

Symptoms of Circumflex Artery Regurgitation:

  1. Shortness of breath
  2. Fatigue
  3. Chest pain or discomfort
  4. Irregular heartbeat (arrhythmia)
  5. Swelling in the legs or abdomen
  6. Dizziness or lightheadedness
  7. Fainting spells (syncope)
  8. Palpitations
  9. Difficulty exercising
  10. Bluish discoloration of the skin (cyanosis)
  11. Reduced exercise tolerance
  12. Heart murmur
  13. Rapid or fluttering heartbeat (palpitations)
  14. Persistent cough
  15. Decreased appetite
  16. Weight loss
  17. Anxiety or panic attacks
  18. Nausea
  19. Difficulty lying flat
  20. Fluid retention leading to edema

Diagnostic Tests for Circumflex Artery Regurgitation:

  1. Echocardiogram
  2. Electrocardiogram (ECG or EKG)
  3. Stress test
  4. Chest X-ray
  5. Cardiac catheterization
  6. Magnetic resonance imaging (MRI)
  7. Computed tomography (CT) scan
  8. Blood tests (to check for biomarkers of heart damage)
  9. Holter monitor (to monitor heart rhythm over 24-48 hours)
  10. Transesophageal echocardiography (TEE)
  11. Doppler ultrasound
  12. Coronary angiography
  13. Nuclear stress test
  14. Exercise stress echocardiogram
  15. B-type natriuretic peptide (BNP) test
  16. Coronary calcium scan
  17. Arterial blood gas (ABG) test
  18. Carotid ultrasound
  19. Ambulatory ECG monitoring
  20. Pulmonary function tests
You Might Also Read  Cutaneous Embolism

Treatments for Circumflex Artery Regurgitation:

  1. Medications to manage symptoms (e.g., diuretics, ACE inhibitors, beta-blockers)
  2. Lifestyle modifications (e.g., dietary changes, exercise regimen)
  3. Valve repair or replacement surgery
  4. Cardiac rehabilitation program
  5. Oxygen therapy
  6. Anticoagulant therapy (blood thinners)
  7. Implantable cardioverter-defibrillator (ICD) placement
  8. Left ventricular assist device (LVAD)
  9. Percutaneous coronary intervention (PCI)
  10. Radiofrequency ablation
  11. Alcohol septal ablation
  12. Mitral valve annuloplasty
  13. Mitral valve leaflet repair
  14. Aortic valve repair or replacement
  15. Tricuspid valve repair or replacement
  16. Watchful waiting with regular monitoring
  17. Antiarrhythmic medications
  18. Inotropic medications
  19. Vasodilators
  20. Statins (cholesterol-lowering drugs)

Drugs Used in the Treatment of Circumflex Artery Regurgitation:

  1. Furosemide (Lasix)
  2. Enalapril (Vasotec)
  3. Metoprolol (Lopressor)
  4. Warfarin (Coumadin)
  5. Digoxin (Lanoxin)
  6. Amiodarone (Cordarone)
  7. Nitroglycerin
  8. Spironolactone (Aldactone)
  9. Rivaroxaban (Xarelto)
  10. Clopidogrel (Plavix)
  11. Atorvastatin (Lipitor)
  12. Simvastatin (Zocor)
  13. Diltiazem (Cardizem)
  14. Amlodipine (Norvasc)
  15. Isosorbide dinitrate (Isordil)
  16. Heparin
  17. Aspirin
  18. Lisinopril (Prinivil, Zestril)
  19. Verapamil (Calan)
  20. Carvedilol (Coreg)

Surgeries for Circumflex Artery Regurgitation:

  1. Valve repair surgery
  2. Valve replacement surgery
  3. Coronary artery bypass grafting (CABG)
  4. Mitral valve annuloplasty
  5. Aortic valve repair or replacement
  6. Tricuspid valve repair or replacement
  7. Maze procedure for atrial fibrillation
  8. Left ventricular reconstruction surgery
  9. Heart transplant
  10. Pulmonary valve repair or replacement


Circumflex artery regurgitation is a complex condition that requires comprehensive management involving various diagnostic tests, treatments, medications, and surgeries. Early detection and appropriate intervention are crucial in improving outcomes and enhancing the quality of life for individuals with this condition. If you suspect you or someone you know may have circumflex artery regurgitation, it’s essential to seek medical attention promptly for proper evaluation and treatment.


Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.