Cefquinome; Indications/Uses, Dosage, Side effects, Interaction ,Pregnancy Cefquinome is a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity. Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Mechanism of action of Cefquinome Cefquinome is a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity. Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Respiratory diseases in horses caused by Streptococcus equi subsp. zooepidemicus and severe bacterial infections with a high risk of septicemia in foals in which Escherichia coli is involved. Pharmacology of Cefquinome Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Respiratory diseases in horses caused by Streptococcus equi subsp. zooepidemicus and severe bacterial infections with a high risk of septicemia in foals in which Escherichia coli is involved. You Might Also Read Doripenem - Uses, Dosage, Side Effects, Interactions ………………………………………..Data or information not available References EU Community Register of Medicinal Products https://ec.europa.eu/health/documents/community-register/html/vo2921.htm https://ec.europa.eu/health/documents/community-register/html/vo2422.htm European Chemicals Agency (ECHA) https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/222498 European Chemicals Agency – ECHA https://www.echa.europa.eu/web/guest/information-on-chemicals/cl-inventory-database/-/discli/details/222498 FDA/SPL Indexing Data https://www.fda.gov/ForIndustry/DataStandards/SubstanceRegistrationSystem-UniqueIngredientIdentifierUNII/ NCIt Cefquinome https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C79564 Springer Nature Wikipedia https://en.wikipedia.org/wiki/Cefquinome PubChem https://pubchem.ncbi.nlm.nih.gov