Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis

Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but very serious skin disorders. They are often caused by reactions to medications or infections. These conditions cause the skin to blister and peel, which can be extremely painful and dangerous.

Types

SJS and TEN are closely related, and some experts consider them as a spectrum of the same condition, with TEN being more severe.

Causes

  1. Medications: Some drugs, including antibiotics and pain relievers, can trigger SJS or TEN in some people.
  2. Infections: Viral and bacterial infections, like herpes and pneumonia, can lead to these conditions.
  3. Genetic factors: Some individuals may have a genetic predisposition that makes them more susceptible.

Symptoms

  1. Fever
  2. Skin rash
  3. Blisters on the skin, mouth, and eyes
  4. Painful skin
  5. Fatigue
  6. Swelling of the face
  7. Sore throat
  8. Difficulty swallowing
  9. Eye redness and irritation

Diagnostic Tests

Doctors diagnose SJS and TEN based on:

  1. Physical examination
  2. Skin biopsy
  3. Blood tests
  4. Evaluation of medical history, including recent medication use

Treatments

  1. Hospitalization: Patients are usually admitted to the hospital for intensive care.
  2. Stopping the Trigger: Identifying and stopping the medication or treating the infection that caused the reaction.
  3. Supportive Care: Pain relief, wound care, and fluids to prevent dehydration.
  4. Immune Globulin Therapy: Some patients may receive immune globulin to reduce the severity.
  5. Eye Care: For eye involvement, ophthalmic care is essential.
  6. Nutrition: Nutritional support through feeding tubes may be necessary.
  7. Avoiding Triggers: In the future, avoid the medication or trigger that caused the condition.

Drugs

  1. Pain relief: Acetaminophen (Tylenol)
  2. Antibiotics: Ciprofloxacin (Cipro), Vancomycin (Vancocin)
  3. Antivirals: Acyclovir (Zovirax)

Please consult a healthcare professional for personalized information on these conditions, as well as specific causes, symptoms, tests, treatments, and drugs for your case.

This simplified explanation provides a basic understanding of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). If you have more specific questions or need detailed information about any aspect of these conditions, please let me know.

Disclaimer: Each person’s journey is unique, always seek the advice of a medical professional before trying any treatments to ensure to find the best plan for you. This guide is for general information and educational purposes only. If you or someone are suffering from this disease condition bookmark this page or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. Thank you for giving your valuable time to read the article.

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References