Benign Symmetric Lipomatosis

Last updated: February 8, 2026Reviewed date: February 8, 2026Reading time: 12 min read
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Benign Symmetric Lipomatosis
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Benign symmetric lipomatosis (BSL), also known as Launois-Bensaude syndrome, is a rare condition characterized by the growth of multiple, symmetrical, benign fat deposits in the neck, shoulder, and back regions. It is a slowly progressive condition that mainly affects middle-aged and elderly men, although women...

For severe symptoms, danger signs, pregnancy, child illness, or sudden worsening, seek urgent medical care.

বাংলা রোগী নোট এখনো যোগ করা হয়নি। পোস্ট এডিটরে “RX Bangla Patient Mode” বক্স থেকে সহজ বাংলা সারাংশ যোগ করুন।

এই তথ্য শিক্ষা ও সচেতনতার জন্য। এটি ডাক্তারি পরীক্ষা, রোগ নির্ণয় বা প্রেসক্রিপশনের বিকল্প নয়।

Article Summary

Benign symmetric lipomatosis (BSL), also known as Launois-Bensaude syndrome, is a rare condition characterized by the growth of multiple, symmetrical, benign fat deposits in the neck, shoulder, and back regions. It is a slowly progressive condition that mainly affects middle-aged and elderly men, although women can also be affected. BSL is classified as a type of lipomatosis, which refers to the overgrowth of fatty tissue...

Key Takeaways

  • This article explains Causes in simple medical language.
  • This article explains Symptoms in simple medical language.
  • This article explains Diagnosis in simple medical language.
  • This article explains Treatment in simple medical language.
Educational health guideWritten for patient understanding and clinical awareness.
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Definition

Benign symmetric lipomatosis (BSL), also known as Launois-Bensaude syndrome, is a rare condition characterized by the growth of multiple, symmetrical, benign fat deposits in the neck, shoulder, and back regions. It is a slowly progressive condition that mainly affects middle-aged and elderly men, although women can also be affected.

BSL is classified as a type of lipomatosis, which refers to the overgrowth of fatty tissue in the body. Lipomatosis can be either benign or malignant, and BSL is a benign form of the condition. The fat deposits in BSL are usually not painful, but they can cause discomfort or disfigurement, and in some cases, they can also interfere with normal movements or activities.

The exact cause of BSL is unknown, but there are several theories that have been proposed. Some researchers believe that it may be due to an inherited genetic predisposition, while others suggest that it may be caused by hormonal imbalances or other environmental factors.

There are several different types of BSL, which can be classified based on the location and size of the fat deposits. The most common types are:

  1. Cervical BSL: This type affects the neck region and is the most common form of BSL. Fat deposits in this area can cause a characteristic “buffalo hump” appearance and can also compress the spinal cord, leading to neurological symptoms.
  2. Thoracic BSL: This type affects the upper back and chest region and can cause a “hunchback” appearance. In severe cases, it can also interfere with breathing.
  3. Scapular BSL: This type affects the shoulder blades and can cause discomfort or pain in the shoulder region.
  4. Limb BSL: This type affects the arms or legs and is the least common form of BSL.

Causes

The exact cause of BSL is unknown, but several factors have been implicated in its development.

  1. Genetics: Studies have shown that BSL can be inherited in an autosomal dominant manner, suggesting a genetic component in its development.
  2. Hormonal Imbalances: Abnormalities in hormonal regulation, particularly of insulin, have been suggested as a contributing factor to BSL. Insulin resistance and high levels of insulin in the blood can lead to an increase in fat storage.
  3. Obesity: Excessive weight and obesity have been linked to the development of BSL. This may be due to the increased fat storage that occurs in obese individuals.
  4. Metabolic Disorders: Metabolic disorders, such as type 2 insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।" data-rx-term="diabetes" data-rx-definition="Diabetes is a condition where blood sugar stays too high because insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।">diabetes, can lead to an increase in fat storage and contribute to the development of BSL.
  5. Medications: Certain medications, such as corticosteroids and antipsychotics, have been linked to the development of BSL due to their ability to increase fat storage.
  6. Alcoholism: Alcoholism can lead to the development of BSL due to the toxic effects of alcohol on the liver, which can disrupt hormonal regulation and increase fat storage.
  7. Endocrine Disorders: Endocrine disorders, such as thyroid gland makes too little hormone. সহজ বাংলা: থাইরয়েড হরমোন কম।" data-rx-term="hypothyroidism" data-rx-definition="Hypothyroidism means the thyroid gland makes too little hormone. সহজ বাংলা: থাইরয়েড হরমোন কম।">hypothyroidism and hypercortisolism, have been linked to the development of BSL due to their effects on hormone regulation and fat storage.
  8. Nutrition: A diet high in fat and sugar can contribute to the development of BSL by increasing fat storage.
  9. Age: BSL is more common in older individuals, and the risk of developing the condition increases with age.
  10. Gender: BSL is more commonly diagnosed in men than in women, although the exact reason for this gender disparity is unknown.
  11. Ethnicity: BSL is more commonly diagnosed in individuals of Mediterranean, Middle Eastern, and South Asian descent.
  12. Family History: A family history of BSL can increase the risk of developing the condition.
  13. Smoking: Smoking has been linked to the development of BSL due to its effects on hormone regulation and fat storage.
  14. Stress: Chronic stress can disrupt hormone regulation and increase fat storage, contributing to the development of BSL.
  15. Sleep Disorders: Sleep disorders, such as sleep apnea, have been linked to the development of BSL due to their effects on hormone regulation and fat storage.
  16. Physical Inactivity: A sedentary lifestyle can contribute to the development of BSL by increasing fat storage and disrupting hormone regulation.
  17. Chronic infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।" data-rx-term="inflammation" data-rx-definition="Inflammation is the body’s response to injury, infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।">Inflammation: Chronic inflammation has been linked to the development of BSL due to its effects on hormone regulation and fat storage.
  18. Environmental Toxins: Exposure to environmental toxins, such as lead and polychlorinated biphenyls (PCBs), has been linked to the development of BSL due to their effects on hormone regulation and fat storage.
  19. Vitamin Deficiencies: Vitamin deficiencies, particularly of vitamins B6 and B12, have been linked to the development of BSL due to their effects on hormone regulation and fat storage.
  20. Infections: Certain infections, such as human immunodeficiency virus (HIV) and hepatitis C, have been linked to the development of BSL due to their effects on hormone regulation and fat storage.

Symptoms

Symptoms that may be associated with BSL:

  1. Fat deposits: The most obvious symptom of BSL is the presence of multiple, soft, rubbery, benign tumors of fat (lipomas) in various parts of the body, including the neck, back, arms, legs, and abdomen.
  2. Symmetrical distribution: The lipomas tend to develop symmetrically on both sides of the body, which is a characteristic feature of BSL.
  3. Increasing size: The lipomas tend to increase in size over time, and can eventually become quite large, causing physical and cosmetic problems.
  4. Pain: Some people with BSL experience discomfort and pain due to the size and distribution of the lipomas.
  5. Reduced mobility: In severe cases, the size of the lipomas can make it difficult to move and perform everyday activities, such as dressing and grooming.
  6. Weakness: Some people with BSL experience weakness in the affected areas, which can make it difficult to perform physical tasks.
  7. Numbness and tingling: Some people with BSL may experience numbness and tingling in the affected areas, which can be caused by pressure on the nerves.
  8. Difficulty breathing: In severe cases, the size of the lipomas can make it difficult to breathe, especially when lying down.
  9. Heart palpitations: Some people with BSL may experience heart palpitations due to the pressure of the lipomas on the heart and chest.
  10. Digestive problems: Some people with BSL may experience digestive problems, such as bloating, constipation, and abdominal pain, due to the pressure of the lipomas on the abdominal organs.
  11. Fatigue: Some people with BSL may experience fatigue and weakness, which can be related to the physical and emotional tendon. সহজ বাংলা: মাংসপেশি/টেনডনে টান।" data-rx-term="strain" data-rx-definition="A strain is injury to a muscle or tendon. সহজ বাংলা: মাংসপেশি/টেনডনে টান।">strain of living with the condition.
  12. Depression: Some people with BSL may experience depression and anxiety due to the physical and cosmetic impact of the condition.
  13. Insecurity: Some people with BSL may feel self-conscious and insecure about their appearance, which can affect their self-esteem and quality of life.
  14. Difficulty sleeping: Some people with BSL may have difficulty sleeping due to the discomfort and pain caused by the lipomas, as well as the difficulty breathing and pressure on the chest.
  15. Skin irritation: The skin over the lipomas can become irritated and red due to friction and pressure, which can cause discomfort and pain.
  16. Scarring: In some cases, the lipomas can become so large that they cause scarring or disfigurement of the affected areas.
  17. Difficulty performing everyday tasks: In severe cases, the size and distribution of the lipomas can make it difficult to perform everyday tasks, such as dressing and grooming.
  18. Difficulty with physical activity: Some people with BSL may have difficulty participating in physical activities, such as sports or exercise, due to the size and distribution of the lipomas.
  19. Difficulty finding clothing that fits: Some people with BSL may have difficulty finding clothing that fits properly, especially in areas where the lipomas are located.

Diagnosis

Diagnostic tests and procedures used for the diagnosis of BSL:

  1. Physical examination: A physical examination is the first step in diagnosing BSL. The doctor will look for the presence of multiple fat deposits on the neck, trunk, and extremities.
  2. Medical history: The doctor will ask about the patient’s medical history and any family history of BSL or similar conditions.
  3. Ultrasound: An ultrasound uses high-frequency sound waves to create images of the internal organs and soft tissues. It can help to identify the location and size of the fat deposits and determine if they are benign or malignant.
  4. CT scan: A CT scan uses X-rays and computer technology to produce detailed images of the body’s internal structures. It can help to determine the size and location of the fat deposits and any other related conditions.
  5. MRI: An MRI uses magnetic fields and radio waves to produce images of the internal structures of the body. It can provide detailed images of the fat deposits and help to rule out any other underlying conditions.
  6. Biopsy: A biopsy involves removing a small sample of tissue from the fat deposit for examination under a microscope. This test can confirm the diagnosis of BSL and rule out any other underlying conditions.
  7. Complete blood count (CBC): A CBC measures the number of red and white blood cells and platelets in the blood. This test can help to determine if there are any underlying conditions that could be contributing to the fat deposits.
  8. Lipid panel: A lipid panel measures the levels of fats, such as cholesterol and triglycerides, in the blood. This test can help to determine if there are any underlying lipid disorders that could be contributing to the fat deposits.
  9. Hormonal tests: Hormonal tests, such as testosterone and estrogen levels, can be performed to determine if there are any hormonal imbalances that could be contributing to the fat deposits.
  10. Thyroid function tests: Thyroid function tests can be performed to determine if there are any thyroid problems that could be contributing to the fat deposits.
  11. Liver function tests: Liver function tests can be performed to determine if there are any liver problems that could be contributing to the fat deposits.
  12. Renal function tests: Renal function tests can be performed to determine if there are any kidney problems that could be contributing to the fat deposits.
  13. Glucose tolerance test: A glucose tolerance test measures the body’s ability to process glucose and can help to determine if there are any underlying glucose intolerance or diabetes issues.
  14. C-reactive protein test: A C-reactive protein test measures the level of inflammation in the body and can help to determine if there are any underlying inflammatory conditions.
  15. Fasting insulin level: A fasting insulin level measures the amount of insulin in the blood after fasting for at least 8 hours. This test can help to determine if there are any underlying insulin resistance issues.
  16. Adiponectin level: Adiponectin is a hormone produced by adipose (fat) tissue. A test to measure the adiponectin level can help to determine if there are any underlying issues with the fat

Treatment

Treatment options for BSL:

  1. Observation: For mild cases of BSL, observation may be the best course of action. In some cases, the condition may stabilize or even improve on its own over time.
  2. Weight management: Maintaining a healthy weight can help reduce the size of fat deposits and slow down the progression of BSL.
  3. Exercise: Regular physical activity can help improve overall health and burn excess fat.
  4. Liposuction: Liposuction is a surgical procedure that removes excess fat from the body using a suction device. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  5. Fat reduction injections: Injections of drugs that reduce fat, such as deoxycholic acid (Kybella), can be used to treat BSL. However, this treatment is still in the experimental stage and its long-term effects are not yet known.
  6. Lipolysis: Lipolysis is a minimally invasive procedure that uses ultrasound or laser energy to break down fat cells. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  7. Mesotherapy: Mesotherapy is a procedure that involves injecting a mixture of drugs and nutrients into the affected areas to break down fat and improve circulation. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  8. Radiofrequency therapy: Radiofrequency therapy uses high-frequency electromagnetic waves to heat and destroy fat cells. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  9. Cryolipolysis: Cryolipolysis is a non-invasive procedure that uses extreme cold temperatures to destroy fat cells. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  10. Laser-assisted liposuction: Laser-assisted liposuction is a surgical procedure that uses laser energy to melt and remove fat. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  11. Endoscopic thoracic sympathectomy (ETS): ETS is a surgical procedure that involves cutting or destroying the sympathetic nerves that control sweating and other functions. This procedure can be used to treat BSL, but it is not a cure and the fat deposits may return over time.
  12. Liposarcoma excision: Liposarcoma excision is a surgical procedure that involves removing a liposarcoma, a type of malignant tumor that can resemble BSL. This procedure is only necessary if a liposarcoma is suspected.
  13. Steroid injections: Steroid injections can be used to reduce inflammation and swelling in the affected areas.
  14. Anti-inflammatory medications: Nonsteroidal anti-inflammatory drugs (NSAIDs) can be used to reduce pain and inflammation in the affected areas.
  15. Pain management: Pain management techniques

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  7. https://www.aad.org/public/diseases/a-z
  8. https://medlineplus.gov/skinconditions.html
  9. https://www.aad.org/about/burden-of-skin-disease
  10. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  11. https://www.cdc.gov/niosh/topics/skin/default.html
  12. https://www.skincancer.org/
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  14. https://www.psoriasis.org/about-psoriasis/
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  17. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  18. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
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  20. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  21. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
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  48. https://orwh.od.nih.gov/


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Safety note: This is not a prescription or diagnosis. For severe symptoms, pregnancy danger signs, children with serious illness, chest pain, breathing difficulty, stroke-like weakness, or major injury, seek urgent care.

Which doctor may help?

Start with a registered doctor or the nearest qualified health center.

What to tell the doctor

  • Write when the problem started and how it changed.
  • Bring old prescriptions, investigation reports, and current medicines.
  • Write allergies, pregnancy status, diabetes, kidney/liver disease, and major past illnesses.
  • Bring one family member if the patient is weak, elderly, confused, or a child.

Questions to ask

  • What is the most likely cause of my symptoms?
  • Which danger signs mean I should go to hospital quickly?
  • Which tests are necessary now, and which can wait?
  • How should I take medicines safely and what side effects should I watch for?
  • When should I come for follow-up?

Tests to discuss

  • Vital signs: temperature, pulse, blood pressure, oxygen saturation
  • Basic physical examination by a clinician
  • CBC, urine test, blood sugar, or imaging only when clinically needed

Avoid these mistakes

  • Do not use antibiotics, steroid tablets/injections, or strong painkillers without proper medical advice.
  • Do not hide pregnancy, kidney disease, ulcer, allergy, or blood thinner use.
  • Do not delay emergency care when danger signs are present.

Medicine safety and first-aid guide

This section is for patient education only. It does not replace a doctor, pharmacist, or emergency care.

Safe first steps

  • Avoid heavy lifting, sudden bending, and prolonged bed rest.
  • Use comfortable posture and gentle movement as tolerated.
  • Discuss physiotherapy, X-ray, or MRI only when clinically needed.

OTC medicine safety

  • For mild back pain, pain-relief medicine may be discussed with a doctor or pharmacist.
  • Avoid repeated painkiller use if you have kidney disease, stomach ulcer, uncontrolled blood pressure, or are taking blood thinners.

Avoid these mistakes

  • Do not start antibiotics without a proper medical decision.
  • Do not use steroid tablets or injections casually for quick relief.
  • Do not delay emergency care because of home remedies.

Get urgent help if

  • Back pain with leg weakness, numbness around private area, loss of urine/stool control, fever, cancer history, or major injury needs urgent care.
Medicine names, dose, and timing must be decided by a qualified clinician or pharmacist after checking age, pregnancy, allergy, other diseases, and current medicines.

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Patient health record and symptom diary

Write your symptoms, medicines already taken, test results, and questions before visiting a doctor. This note stays on your device unless you print or copy it.

Doctor to discuss: Doctor / qualified healthcare provider
Tests to discuss with doctor
  • Basic vital signs: temperature, pulse, blood pressure, oxygen level if needed
  • Relevant blood, urine, imaging, or specialist tests only after clinical assessment
Questions to ask
  • What is the most likely cause of my symptoms?
  • Which warning signs mean I should go to emergency care?
  • Which tests are really needed now?
  • Which medicines are safe for my age, pregnancy status, allergy, kidney/liver/stomach condition, and current medicines?

Emergency warning signs such as chest pain, severe breathing difficulty, sudden weakness, confusion, severe dehydration, major injury, or loss of bladder/bowel control need urgent medical care. Do not wait for online information.

Safe pathway to proper treatment

Care roadmap for: Benign Symmetric Lipomatosis

Use this simple roadmap to understand the next safe steps. It is educational and does not replace examination by a doctor.

Go to emergency care if you notice:
  • Severe or rapidly worsening symptoms
  • Breathing difficulty, chest pain, fainting, confusion, severe weakness, major injury, or severe dehydration
Doctor / service to discuss: Qualified healthcare provider; specialist depends on symptoms and examination.
  1. Step 1

    Check danger signs first

    If danger signs are present, seek emergency care and do not wait for online information.

  2. Step 2

    Record the symptom story

    Write when symptoms started, severity, medicines already taken, allergies, pregnancy status, and test results.

  3. Step 3

    Visit a qualified clinician

    A doctor, nurse, or qualified healthcare provider can examine you and decide which tests or treatment are needed.

  4. Step 4

    Do only useful tests

    Do tests after clinical assessment. Avoid unnecessary tests, random antibiotics, or repeated medicines without diagnosis.

  5. Step 5

    Follow up and return early if worse

    If symptoms worsen, new warning signs appear, or treatment is not helping, return for review quickly.

Rural patient practical tips
  • Take a written symptom diary and all previous prescriptions/test reports.
  • Do not hide medicines already taken, even herbal or over-the-counter medicines.
  • Ask which warning signs mean urgent referral to hospital.

This roadmap is for education. A real diagnosis and treatment plan requires history, examination, and clinical judgment.

RX Patient Help

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Emergency first: Severe chest pain, breathing trouble, unconsciousness, stroke signs, severe injury, heavy bleeding, or rapidly worsening symptoms need urgent local medical care now.

Frequently Asked Questions

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Seek urgent care for severe symptoms, rapidly worsening condition, breathing difficulty, severe pain, neurological changes, or any emergency warning sign.

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  8. Epistaxis

    DefinitionEpistaxis is the medical word for a nosebleed. It means that blood is coming out from inside the nose, from small blood vessels in the lining...

    February 25, 2026 • Rx Autoimmune, Genetic and Rare Diseases (A - Z)
  9. Nose Bleed

    DefinitionA nosebleed is when blood comes out from inside the nose because tiny blood vessels (capillaries) in the nose lining break and leak. Doctors call this...

    February 24, 2026 • Rx Autoimmune, Genetic and Rare Diseases (A - Z)
  10. Combined Oxidative Phosphorylation Defect Type 14

    DefinitionCombined oxidative phosphorylation defect type 14 (often written as COXPD14) is a very rare, serious genetic disease that affects how the tiny “power stations” inside our...

    February 19, 2026 • Rx Autoimmune, Genetic and Rare Diseases (A - Z)