Disease A-Z Library

Rx Neurology (A – Z)

Browse plain-English disease and condition guides, including symptoms, causes, diagnosis, treatment options, prevention, and when to seek medical care.

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Diseases A-Z

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Disease A-Z Library

Cayman Type Cerebellar Ataxia

Cayman type cerebellar ataxia (often shortened to “Cayman ataxia”) is a rare inherited brain development condition that starts from birth or very early infancy. It mainly...

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Cerebral Myiasis

Cerebral myiasis means fly larvae (maggots) infest tissue in or around the brain. It is extremely rare. In most reported cases, larvae get access through an...

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Spongy Degeneration of the Brain

Spongy degeneration of the brain means the brain’s white matter (the wiring that carries messages) develops many tiny fluid-filled holes and becomes soft and swollen. In...

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Spongiform Leucodystrophy

Spongiform leucodystrophy is a rare brain disease. It mainly affects babies and young children. “Leuco-” means white, and “dystrophy” means damage or poor growth. In this...

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Aminoacylase-2 Deficiency

Aminoacylase-2 deficiency—the condition better known today as Canavan disease (aspartoacylase deficiency) is a rare, inherited brain disease. Doctors now call it Canavan disease. It happens when...

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Trigonocephaly C Syndrome

Trigonocephaly C syndrome (often shortened to C syndrome or Opitz trigonocephaly syndrome / OTCS) is an ultra-rare genetic condition. The key sign is trigonocephaly—a triangular-shaped forehead...

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Opitz C Trigonocephaly

Opitz C trigonocephaly, also called C syndrome or Opitz trigonocephaly syndrome, is a very rare genetic condition. The front seam of the skull (the metopic suture)...

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Birk-Barel Syndrome

Birk-Barel syndrome is a very rare, inherited brain-development disorder caused by changes in a single gene called KCNK9. This gene makes a potassium “leak” channel called...

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Cerebrovascular Ferrocalcinosis

Cerebrovascular ferrocalcinosis means there is abnormal build-up of minerals—mainly calcium and often iron-related deposits—within the walls of small blood vessels and the tissues around them inside...

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Bilateral Polymicrogyria

Bilateral polymicrogyria is a problem in how the brain’s surface (the cortex) forms before birth. In PMG, the brain makes too many very small folds (gyri),...

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