Category: Drugs (A – Z)

Selumetinib is an orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent inhibitor of mitogen-activated protein kinase kinase (MEK or MAPK/ERK kinase) 1...

Tebentafusp is a bispecific gp100 peptide-HLA-directed CD3 T cell engager used to treat unresectable or metastatic uveal melanoma. Tebentafusp is a gp100 peptide-HLA-directed CD3...

Pembrolizumab is a monoclonal antibody used to treat certain types of cancer. It works by blocking a certain protein in the body that helps...

Palifermin is a modified truncated form of human keratinocyte growth factor produced by recombinant DNA technology. Palifermin is used to treat oral sores and...

Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA,...

Ruxolitinib is a small molecule Janus kinase inhibitor that is used in the treatment of intermediate or high-risk myelofibrosis and resistant forms of polycythemia...

Ixazomib is an active metabolite of MLN9708, a second-generation, boron-containing peptide proteasome inhibitor (PI) or proteasome inhibitor with potential antineoplastic activity. Ixazomib binds to and...