Health Benefits of Aloe Vera – Dosage, Side Effects

Last updated: February 8, 2026Reviewed date: February 8, 2026Reading time: 7 min read
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Health Benefits of Aloe Vera/Aloe vera is a succulent plant species of the genus Aloe. Having some 500 species, Aloe is widely distributed and is considered an invasive species in many world regions.[rx][rx] An evergreen perennial, it originates from the Arabian Peninsula but grows wild in tropical, semi-tropical, and arid climates around the world.[rx] It is cultivated for...

For severe symptoms, danger signs, pregnancy, child illness, or sudden worsening, seek urgent medical care.

বাংলা রোগী নোট এখনো যোগ করা হয়নি। পোস্ট এডিটরে “RX Bangla Patient Mode” বক্স থেকে সহজ বাংলা সারাংশ যোগ করুন।

এই তথ্য শিক্ষা ও সচেতনতার জন্য। এটি ডাক্তারি পরীক্ষা, রোগ নির্ণয় বা প্রেসক্রিপশনের বিকল্প নয়।

Article Summary

Health Benefits of Aloe Vera/Aloe vera is a succulent plant species of the genus Aloe. Having some 500 species, Aloe is widely distributed and is considered an invasive species in many world regions.[rx][rx] An evergreen perennial, it originates from the Arabian Peninsula but grows wild in tropical, semi-tropical, and arid climates around the world.[rx] It is cultivated for commercial products, mainly as a topical treatment used over centuries.[rx][rx] The species is attractive for decorative purposes and succeeds indoors as a potted...

Key Takeaways

  • This article explains Aloe Vera Traditional Medicinal Uses and Health benefits in simple medical language.
  • This article explains Science-Based Studies and Research in simple medical language.
  • This article explains How to Get and How to Use in simple medical language.
  • This article explains Dosage, Warnings, and Side Effects in simple medical language.
Educational health guideWritten for patient understanding and clinical awareness.
Reviewed content workflowUse writer and reviewer profiles for stronger trust.
Emergency safety firstUrgent warning signs are highlighted below.

Seek urgent medical care if you notice

These warning signs are general safety guidance. Local emergency numbers and clinical judgment should always come first.

  • Severe symptoms, breathing difficulty, fainting, confusion, or rapidly worsening illness.
  • New weakness, severe pain, high fever, or symptoms after a serious injury.
  • Any symptom that feels urgent, unusual, or unsafe for the patient.
1

Emergency now

Use emergency care for severe, sudden, rapidly worsening, or life-threatening symptoms.

2

See a doctor

Book a professional medical evaluation if symptoms persist, worsen, recur often, affect daily activities, or occur in a high-risk patient.

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Use this article to understand possible causes, tests, treatment options, prevention, and questions to ask your clinician.

Health Benefits of Aloe Vera/Aloe vera is a succulent plant species of the genus Aloe. Having some 500 species, Aloe is widely distributed and is considered an invasive species in many world regions.[rx][rx]

An evergreen perennial, it originates from the Arabian Peninsula but grows wild in tropical, semi-tropical, and arid climates around the world.[rx] It is cultivated for commercial products, mainly as a topical treatment used over centuries.[rx][rx] The species is attractive for decorative purposes and succeeds indoors as a potted plant.[rx]

It is used in many consumer products, including beverages, skin lotion, cosmetics, ointments or in the form of gel for minor burns and sunburns. There is little clinical evidence for the effectiveness or safety of Aloe vera extract as a cosmetic or topical drug.[rx][rx] The name derives from Latin as aloe and vera (“true”).

Scientific Name: Aloe barbadensis, Aloe Vera

Aloe vera is one of the oldest known herbal medicine that can be traced back in ancient Egypt. Aloe vera plant was depicted on stone carvings and in Eber’s papyrus in 16th Century BCE, found in burial grounds of deceased pharaohs..

Aloe vera was historically used to heal wounds and treat various skin conditions, Aloe was also taken orally as a laxative. Nowadays, aloe extract is still popularly used as a home remedy for skin problems such as psoriasis, burns, sunburns, insect bites, and others. Aloe vera can be found in many skin products such as lotions, gels, and sunblocks. Other folkloric uses include treatment of pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।" data-rx-term="arthritis" data-rx-definition="Arthritis means joint inflammation causing pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।">arthritis, asthma, insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।" data-rx-term="diabetes" data-rx-definition="Diabetes is a condition where blood sugar stays too high because insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।">diabetes, epilepsy, and osteoarthritis.

Aloe Vera is a herb that grows in warm climates and is widely distributed in the Philippines, India, and Africa. Aloe Vera is widely used as traditional herbal medicine in China, Japan, Russia, South Africa, the United States, Jamaica, Latin America, and India. Aloe Vera is frequently cited as being used in herbal medicine for its infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।" data-rx-term="inflammation" data-rx-definition="Inflammation is the body’s response to injury, infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।">inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।" data-rx-term="anti-inflammatory" data-rx-definition="Anti-inflammatory means reducing inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।">anti-inflammatory, regenerative, anti-bacterial and anti-fungal, and healing properties.

Aloe Vera is a herb that grows up to 35 cm in height with green leaves. Aloe Vera leaves are about 6 cm wide that grows up tapering with spiny margins. Aloe Vera flower grows erect from the herb to as much as twice the height of the plant. Aloe Vera flowers are yellow to red-yellow in a color that grows to about 2cm.

Aloe Vera Traditional Medicinal Uses and Health benefits

Aloe Vera in Traditional and Folkloric Medicine For Skin Problems

Aloe Vera is traditionally used to treat the following skin conditions

  • skin burns,
  • scalds,
  • scrapes,
  • sunburn
  • wounds
  • psoriasis and others

Aloe Vera juice or the fleshy leaf is applied directly to the affected skin, providing relief and believed to improve healing.

Aloe Vera is used for the treatment of hair related problems

  • Dandruff,
  • Thinning and falling hair,
  • Baldness.

Fresh Aloe Vera juice or sap are massaged to the affected scalp and let it stay for a few minutes before washing.

Aloe Vera, Herbal Medicine For Conjunctivitis, Stomachic, Hemorrhoids and insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।" data-rx-term="diabetes" data-rx-definition="Diabetes is a condition where blood sugar stays too high because insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।">Diabetes

  • Aloe Vera is used in conjunctivitis, Aloe leaf juice is applied to the outer eyelid
  • In small doses, Aloe Vera is considered stomachic tonic; in large doses, as purgative.
  • For hemorrhoids, Aloe Vera cuticle from its leaves is used as a suppository for hemorrhoids
  • In some Arabian regions, Aloe Vera is used to treating insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।" data-rx-term="diabetes" data-rx-definition="Diabetes is a condition where blood sugar stays too high because insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।">diabetes.

Science-Based Studies and Research

Aloe Vera Mechanism of action in disease prevention

Aloe vera has several active constituents and most of them have therapeutic implications for disease prevention and treatment through the modulation of various biological and genetic activities. The possible mechanisms of actions of Aloe vera are described as follows:

  1. Aloe vera has aloe-emodin (AE), aloin (barbaloin), anthracene, and emodin found to be relevant to cancer prevention owing to the activation and inactivation of molecular pathways associated with them.
  2. Aloe vera functions as an antioxidant through free radical and superoxide radical-scavenging activities and infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।" data-rx-term="inflammation" data-rx-definition="Inflammation is the body’s response to injury, infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।">inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।" data-rx-term="anti-inflammatory" data-rx-definition="Anti-inflammatory means reducing inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।">anti-inflammatory activities via inhibition of prostaglandin E2 production from arachidonic acid and also inhibition of various transcription factors and the activities of enzymes including lipoxygenase and cyclooxygenase.
  3. Aloe vera shows antimicrobial activity by rupturing bacterial cell walls. Earlier studies have reported the infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।" data-rx-term="inflammation" data-rx-definition="Inflammation is the body’s response to injury, infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।">inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।" data-rx-term="anti-inflammatory" data-rx-definition="Anti-inflammatory means reducing inflammation, pain, or swelling. সহজ বাংলা: প্রদাহ/ফোলা/ব্যথা কমায়।">anti-inflammatory and antibacterial properties of Aloe vera gel.

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557234/

Aloe Vera has Anti Leukemic Function through its Anti-Mutagenic Activity

A study that isolated di(2)-Ethylhexyl)phthalate (DEHP) from Aloe vera found that Aloe Vera exhibited growth inhibition against three leukemic cell lines and reduced AF-2-induced mutagenicity. DEHP was considered the active principle responsible for the anti-leukemic and anti-mutagenic effects in vitro.

Extracts of Aloe vera Linne have been found to exhibit cytotoxicity against human tumor cell lines.

Source: https://www.ncbi.nlm.nih.gov/pubmed/10864149

Aloe vera has Wound Healing, Anti-cancer and Immune stimulation Activities

Study isolated a major carbohydrate fraction from the gel of Aloe vera leaf. It has been claimed to accelerate wound healing, immune stimulation and have anti-cancer and anti-viral effects. The study showed acemannan an extract found from Aloe vera stimulates cytokine production, nitric oxide release. The production of cytokines IL-6 and TNF-alpha were acemannan dose-dependent. The results suggest acemannan may function, in part, through macrophage activation.

Source: https://www.ncbi.nlm.nih.gov/pubmed/25233608

Aloe Vera, Promotes Bone Regeneration and Formation (osteoformation)

Studies suggest that acemannan, a polysaccharide extracted from Aloe vera gel, could affect bone formation.  Acemannan could function as a bioactive molecule inducing bone formation by stimulating BMSCs proliferation, differentiation into osteoblasts, and extracellular matrix synthesis. Acemannan extracted from Aloe vera could be a candidate for natural biomaterial for bone regeneration.

Source: https://www.ncbi.nlm.nih.gov/pubmed/23315202

Aloe Vera for Biochemotherapy: An effective support for Chemotherapy

The study showed the percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone. The study suggests Aloe may be beneficial to use with chemotherapy to increase efficacy in terms of both tumor regression and survival time.

Aloe Vera as Antigenotoxic :

Study showed antigenotoxic potentials of aloe and suggests a potential use in the prevention of DNA damage caused by chemical agents.

Aloe-emodin / Anticancer / Antiproliferative :

Study sh owed aloe-emodin inhibited cell proliferation and induced apoptosis in two human liver cancer cell lines, but with different antiproliferative mechanisms. Results suggest aloe-emodin may be useful in liver cancer prevention.

Aloeride / Immunostimulatory Activity :

Study characterized a new immunostimulatory polysaccharide, Aloeride, from commercial aloe vera juice

How to Get and How to Use

Where can I get or buy Aloe Vera?

Aloe vera are widely cultivated and generally grown in pots. It can be bought it from your local horticulturist and at a time at home depot shops as an ornamental plant. Aloe vera is also widely used as an ingredient in cosmetic and herbal preparations.

Aloe vera leaves contain a clear gel that is often used as a topical ointment. The green part of the Aloe leaf that surrounds the gel can be used to produce a juice or a dried substance (called latex) that is taken by mouth.

Dosage, Warnings, and Side Effects

  • Use of topical aloe vera is not associated with significant side effects.
  • A 2-year National Toxicology Program (NTP) study on oral consumption of non-decolorized whole leaf extract of aloe vera found clear evidence of carcinogenic activity in male and female rats, based on tumors of the large intestine. According to the NTP, from what is known right now there is nothing that would lead them to believe that these findings are not relevant to humans. However, more information, including how individuals use different types of aloe vera products, is needed to determine the potential risks to humans.
  • Abdominal cramps and diarrhea have been reported with oral use of aloe vera.
  • Diarrhea, caused by the laxative effect of oral aloe vera, can decrease the absorption of many drugs.
  • People with insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।" data-rx-term="diabetes" data-rx-definition="Diabetes is a condition where blood sugar stays too high because insulin is low or not working well. সহজ বাংলা: রক্তে চিনি বেশি থাকার রোগ।">diabetes who use glucose-lowering medication should be cautious if also taking aloe vera by mouth because preliminary studies suggest aloe may lower blood glucose levels.
  • There have been a few case reports of acute hepatitis from aloe vera taken orally. However, the evidence is not definitive.
Doctor visit helper

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A simple rural-patient checklist to help you explain symptoms clearly, ask better questions, and avoid unsafe self-treatment.

Safety note: This is not a prescription or diagnosis. For severe symptoms, pregnancy danger signs, children with serious illness, chest pain, breathing difficulty, stroke-like weakness, or major injury, seek urgent care.

Which doctor may help?

Start with a registered doctor or the nearest qualified health center.

What to tell the doctor

  • Write when the problem started and how it changed.
  • Bring old prescriptions, investigation reports, and current medicines.
  • Write allergies, pregnancy status, diabetes, kidney/liver disease, and major past illnesses.
  • Bring one family member if the patient is weak, elderly, confused, or a child.

Questions to ask

  • What is the most likely cause of my symptoms?
  • Which danger signs mean I should go to hospital quickly?
  • Which tests are necessary now, and which can wait?
  • How should I take medicines safely and what side effects should I watch for?
  • When should I come for follow-up?

Tests to discuss

  • Vital signs: temperature, pulse, blood pressure, oxygen saturation
  • Basic physical examination by a clinician
  • CBC, urine test, blood sugar, or imaging only when clinically needed

Avoid these mistakes

  • Do not use antibiotics, steroid tablets/injections, or strong painkillers without proper medical advice.
  • Do not hide pregnancy, kidney disease, ulcer, allergy, or blood thinner use.
  • Do not delay emergency care when danger signs are present.

Medicine safety and first-aid guide

This section is for patient education only. It does not replace a doctor, pharmacist, or emergency care.

Safe first steps

  • Use oral rehydration solution and safe fluids to prevent dehydration.
  • Continue safe, light food as tolerated.
  • Seek care for children, older adults, pregnancy, or chronic illness.

OTC medicine safety

  • ORS is usually safer than unnecessary antibiotics for simple watery diarrhea.
  • Do not use anti-diarrhea stopping medicines if there is blood in stool or high fever unless a doctor advises.

Avoid these mistakes

  • Do not start antibiotics without a proper medical decision.
  • Do not use steroid tablets or injections casually for quick relief.
  • Do not delay emergency care because of home remedies.

Get urgent help if

  • Blood in stool, severe dehydration, persistent vomiting, very low urine, or lethargy needs urgent care.
Medicine names, dose, and timing must be decided by a qualified clinician or pharmacist after checking age, pregnancy, allergy, other diseases, and current medicines.

For rural patients and family caregivers

Patient health record and symptom diary

Write your symptoms, medicines already taken, test results, and questions before visiting a doctor. This note stays on your device unless you print or copy it.

Doctor to discuss: Doctor / qualified healthcare provider
Tests to discuss with doctor
  • Basic vital signs: temperature, pulse, blood pressure, oxygen level if needed
  • Relevant blood, urine, imaging, or specialist tests only after clinical assessment
Questions to ask
  • What is the most likely cause of my symptoms?
  • Which warning signs mean I should go to emergency care?
  • Which tests are really needed now?
  • Which medicines are safe for my age, pregnancy status, allergy, kidney/liver/stomach condition, and current medicines?

Emergency warning signs such as chest pain, severe breathing difficulty, sudden weakness, confusion, severe dehydration, major injury, or loss of bladder/bowel control need urgent medical care. Do not wait for online information.

Safe pathway to proper treatment

Care roadmap for: Health Benefits of Aloe Vera – Dosage, Side Effects

Use this simple roadmap to understand the next safe steps. It is educational and does not replace examination by a doctor.

Go to emergency care if you notice:
  • Severe or rapidly worsening symptoms
  • Breathing difficulty, chest pain, fainting, confusion, severe weakness, major injury, or severe dehydration
Doctor / service to discuss: Qualified healthcare provider; specialist depends on symptoms and examination.
  1. Step 1

    Check danger signs first

    If danger signs are present, seek emergency care and do not wait for online information.

  2. Step 2

    Record the symptom story

    Write when symptoms started, severity, medicines already taken, allergies, pregnancy status, and test results.

  3. Step 3

    Visit a qualified clinician

    A doctor, nurse, or qualified healthcare provider can examine you and decide which tests or treatment are needed.

  4. Step 4

    Do only useful tests

    Do tests after clinical assessment. Avoid unnecessary tests, random antibiotics, or repeated medicines without diagnosis.

  5. Step 5

    Follow up and return early if worse

    If symptoms worsen, new warning signs appear, or treatment is not helping, return for review quickly.

Rural patient practical tips
  • Take a written symptom diary and all previous prescriptions/test reports.
  • Do not hide medicines already taken, even herbal or over-the-counter medicines.
  • Ask which warning signs mean urgent referral to hospital.

This roadmap is for education. A real diagnosis and treatment plan requires history, examination, and clinical judgment.

RX Patient Help

Ask a health question safely

Write your symptom story. A health professional or site editor can review it before any answer is prepared. This box is not for emergency care.

Emergency first: Severe chest pain, breathing trouble, unconsciousness, stroke signs, severe injury, heavy bleeding, or rapidly worsening symptoms need urgent local medical care now.

Frequently Asked Questions

Aloe Vera Traditional Medicinal Uses and Health benefitsAloe Vera in Traditional and Folkloric Medicine For Skin Problems Aloe Vera is traditionally used to treat the following skin conditionsskin burns, scalds, scrapes, sunburn wounds psoriasis and othersAloe Vera juice or the fleshy leaf is applied directly to the affected skin, providing relief and believed to improve healing. Aloe Vera is used for the treatment of hair related problemsDandruff, Thinning and falling hair, Baldness.Fresh Aloe Vera juice or sap are massaged to the affected scalp and let it stay for a few minutes before washing. Aloe Vera, Herbal Medicine For Conjunctivitis, Stomachic, Hemorrhoids and DiabetesAloe Vera is used in conjunctivitis, Aloe leaf juice is applied to the outer eyelid In small doses, Aloe Vera is considered stomachic tonic; in large doses, as purgative. For hemorrhoids, Aloe Vera cuticle from its leaves is used as a suppository for hemorrhoids In some Arabian regions, Aloe Vera is used to treating diabetes.Science-Based Studies and ResearchAloe Vera Mechanism of action in disease prevention Aloe vera has several active constituents and most of them have therapeutic implications for disease prevention and treatment through the modulation of various biological and genetic activities. The possible mechanisms of actions of Aloe vera are described as follows: Aloe vera has aloe-emodin (AE), aloin (barbaloin), anthracene, and emodin found to be relevant to cancer prevention owing to the activation and inactivation of molecular pathways associated with them. Aloe vera functions as an antioxidant through free radical and superoxide radical-scavenging activities and anti-inflammatory activities via inhibition of prostaglandin E2 production from arachidonic acid and also inhibition of various transcription factors and the activities of enzymes including lipoxygenase and cyclooxygenase. Aloe vera shows antimicrobial activity by rupturing bacterial cell walls. Earlier studies have reported the anti-inflammatory and antibacterial properties of Aloe vera gel.Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557234/Aloe Vera has Anti Leukemic Function through its Anti-Mutagenic Activity A study that isolated di(2)-Ethylhexyl)phthalate (DEHP) from Aloe vera found that Aloe Vera exhibited growth inhibition against three leukemic cell lines and reduced AF-2-induced mutagenicity. DEHP was considered the active principle responsible for the anti-leukemic and anti-mutagenic effects in vitro.Extracts of Aloe vera Linne have been found to exhibit cytotoxicity against human tumor cell lines.Source: https://www.ncbi.nlm.nih.gov/pubmed/10864149Aloe vera has Wound Healing, Anti-cancer and Immune stimulation Activities Study isolated a major carbohydrate fraction from the gel of Aloe vera leaf. It has been claimed to accelerate wound healing, immune stimulation and have anti-cancer and anti-viral effects. The study showed acemannan an extract found from Aloe vera stimulates cytokine production, nitric oxide release. The production of cytokines IL-6 and TNF-alpha were acemannan dose-dependent. The results suggest acemannan may function, in part, through macrophage activation.Source: https://www.ncbi.nlm.nih.gov/pubmed/25233608 Aloe Vera, Promotes Bone Regeneration and Formation (osteoformation) Studies suggest that acemannan, a polysaccharide extracted from Aloe vera gel, could affect bone formation.  Acemannan could function as a bioactive molecule inducing bone formation by stimulating BMSCs proliferation, differentiation into osteoblasts, and extracellular matrix synthesis. Acemannan extracted from Aloe vera could be a candidate for natural biomaterial for bone regeneration.Source: https://www.ncbi.nlm.nih.gov/pubmed/23315202 Aloe Vera for Biochemotherapy: An effective support for Chemotherapy The study showed the percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone. The study suggests Aloe may be beneficial to use with chemotherapy to increase efficacy in terms of both tumor regression and survival time. Aloe Vera as Antigenotoxic : Study showed antigenotoxic potentials of aloe and suggests a potential use in the prevention of DNA damage caused by chemical agents. Aloe-emodin / Anticancer / Antiproliferative : Study sh owed aloe-emodin inhibited cell proliferation and induced apoptosis in two human liver cancer cell lines, but with different antiproliferative mechanisms. Results suggest aloe-emodin may be useful in liver cancer prevention. Aloeride / Immunostimulatory Activity : Study characterized a new immunostimulatory polysaccharide, Aloeride, from commercial aloe vera juiceHow to Get and How to UseWhere can I get or buy Aloe Vera?

Aloe vera are widely cultivated and generally grown in pots. It can be bought it from your local horticulturist and at a time at home depot shops as an ornamental plant. Aloe vera is also widely used as an ingredient in cosmetic and herbal preparations. Aloe vera leaves contain a clear gel that is often used as a topical ointment. The green part of the Aloe leaf that surrounds the gel can be used to produce a juice or a…

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    Aloe Barbadensis/Sabila is one of the oldest known herbal medicine that can be traced back to ancient Egypt. Sabila plant was depicted on stone carvings and...

    October 16, 2021 • Rx Harbal, Unani & Ayurvedic Medicine (A-Z)