Copper – Uses, Indications, Dosage, Interactions

Patient Tools

Read, save, and share this guide

Use these quick tools to make this medical article easier to read, print, save, or share with a family member.

On this page11 sections

Article Summary

Copper is a mineral that is found throughout the body. It helps your body make red blood cells and keeps nerve cells and your immune system healthy. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA. Copper helps the body absorb iron. Your body also...

Before reading

RX Patient Tools

Use these quick guides before reading the article, or return to them when you need help preparing questions for a doctor.

Start here Choose the right pathway for symptoms, reports, medicines, or urgent warning signs. Disease article roadmap Read this topic step by step: meaning, symptoms, warning signs, diagnosis, treatment, prevention, and follow-up. Treatment planner Prepare questions about treatment choices, benefits, risks, side effects, and follow-up. Family & caregiver guide Organize symptoms, reports, medicines, questions, and follow-up safely. Nutrition & diet guide Prepare food, hydration, supplement, and medicine-timing questions safely. Prevention guide Organize risk factors, protective habits, screening, and warning signs. Recovery guide Prepare a safe plan for activity, rehabilitation, warning signs, and follow-up.
Educational health guideWritten for patient understanding and clinical awareness.
Reviewed content workflowUse writer and reviewer profiles for stronger trust.
Emergency safety firstUrgent warning signs are highlighted below.
Choose your reading view

Patient View highlights a simple learning journey. Clinical View reveals structure, evidence, and editorial completeness.

Definition

Copper is a mineral that is found throughout the body. It helps your body make red blood cells and keeps nerve cells and your immune system healthy. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA. Copper helps the body absorb iron. Your body also needs copper to make energy.

Your body does not need much copper. Many people do not get enough copper in their diet, but it is rare to be truly deficient in copper. Signs of possible copper deficiency include , low body temperature, bone fractures and , low , irregular heartbeat, loss of pigment from the skin, and problems.

People who take high amounts of zinc, iron, or vitamin C may need more copper, but you should ask your health care provider before taking copper supplements. Too much copper can be dangerous.

Foods that contain copper include oysters, , whole grain breads and cereals, shellfish, dark green leafy vegetables, dried legumes, nuts, and chocolate.

Uses

Anemia

Taking copper supplements may help people who have anemia because of copper deficiency. Copper works together with iron to form red blood cells.

Animal studies suggest that taking copper by mouth may help prevent and slow , but evidence in humans is lacking. Copper bracelets are often marketed to people with both osteoarthritis and as a way to relieve symptoms, but there is no evidence that they work.

Osteoporosis

There is some slight evidence that taking copper along with zinc, manganese, and calcium might help slow the rate of bone loss among postmenopausal women.

Dietary Sources

Copper is found in these foods:

  • Seafood, such as oysters, squid, lobster, mussels, crab, and clams
  • Organ meats, such as beef liver, , and heart
  • Nuts and nut butters, such as cashews, filberts, macadamia nuts, pecans, almonds, and pistachios
  • Legumes, such as soybeans, lentils, navy beans, and peanuts
  • Chocolate, such as unsweetened or semisweet baker’s chocolate and cocoa
  • Enriched cereals, such as bran flakes, shredded wheat, and raisin bran
  • Fruits and vegetables, such as dried fruits, mushrooms, tomatoes, potatoes, sweet potatoes, bananas, grapes, and avocado
  • Blackstrap molasses
  • Black pepper

Available Forms

Multivitamins that include minerals usually have copper. Copper is also available as a separate oral supplement, and can be found as a topical gel, and in topical solutions.

How to Take It

The best way to get enough copper is through your diet. For your body to use copper, you need to have a balance of zinc and manganese. The following lists provide the recommended daily dietary intake of copper for children and adults from the Food and Nutrition Board at the Institute of Medicine.

Pediatric

  • For infants from birth to 6 months: 200 mcg daily
  • For infants 7 to 12 months: 220 mcg daily
  • For children 1 to 3 years: 340 mcg daily
  • For children 4 to 8 years: 440 mcg daily
  • For children 9 to 13 years: 700 mcg daily
  • For children 14 to 18 years: 890 mcg daily

Children should get copper from foods. DO NOT give copper supplements to children.

Adult

  • For adults 19 years and older: 900 mcg daily
  • For pregnant women: 1,000 mcg daily
  • For breastfeeding women: 1,300 mcg daily

If you take a copper supplement, you should also take a zinc supplement (8 to 15 mg of zinc for every 1 mg of copper), as an imbalance of these two minerals can cause other health problems.

Precautions

Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a knowledgeable health care provider.

Too much copper can cause , , , , , , , and a metallic taste in the mouth. Copper toxicity is rare but can cause heart problems, , coma, even death. DO NOT use copper supplements if you have diarrhea.

Water containing copper concentrations greater than 6 mg/L may cause stomach problems, such as nausea and vomiting. If you have well water, you may want to get the water tested for mineral content.

You can also get copper without knowing it from using copper cookware and from water coming through new copper pipes. Avoid unlined copper cookware. Copper can leach out of pipes into water, especially hot water, if it sits in copper pipes for a long time. Cook with cold water to avoid problems. Flushing the pipes by running cold water for 2 to 3 minutes can reduce copper. If you have blue-green stains around your faucet or sink, or if you detect a metallic taste to your water, you may want to have your water tested by a certified laboratory.

Children and people with Wilson disease (which causes a build up of copper in the brain, liver, kidneys, and eyes), and people with conditions including copper toxicosis and childhood , should not take copper supplements.

Possible Interactions

If you are being treated with any of the following medications, you should not use copper supplements without first talking to your health care provider.

pills and estrogen following : Birth control medications and estrogen replacement for post-menopausal women can increase blood levels of copper.

Nonsteroidal drugs (NSAIDs): These relievers include aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve). Copper binds to NSAIDs and may enhance their anti-inflammatory activity.

Penicillamine: Penicillamine, a medication used to treat Wilson disease and rheumatoid arthritis, reduces copper levels. Copper may lower the amount of penicillamine your body absorbs.

Allopurinol (Zyloprim): Test tube studies suggest that allopurinol, a medication used to treat , may reduce copper levels.

Cimetidine (Tagamet): Animal studies show that cimetidine, a medication used to treat ulcers and gastric esophageal reflux disease (), may raise copper levels in the body.

Nifedipine (Procardia or Adalat): In a human study, people who took nifedipine had lower levels of copper in their red blood cells.

Zinc: Several laboratory and human studies have found that taking high levels of zinc supplements over long periods of time may lower the body’s ability to absorb copper. The same does not seem to be true of eating foods that have copper. Ask your provider if you need zinc and copper supplementation.

 

Araya M, Pizarro F, Olivares M, Arredondo M, Gonzalez M, Mendez M. Understanding copper homeostasis in humans and copper effects on health. Biol Res . 2006;39(1):183-7.

Borkow G, Gabbay J, Zatcoff RC. Could wounds not heal due to too low copper levels? Med Hypotheses . 2008;70(3):610-3.

Bugel, S., Harper, A., Rock, E., O’Connor, J. M., Bonham, M. P., and , J. J. Effect of copper supplementation on indices of copper status and certain CVD risk markers in young healthy women. BrJ Nutr . 2005;94(2):231-236.

Christen Y. Oxidative stress and Alzheimer’s disease. Am J Clin Nutr . 2000;71(2):621S-629S.

Daroff: Bradley’s Neurology in Clinical Practice . 6th ed. Philadelphia, PA: Elsevier Saunders; 2012.

Geerling BJ, Badart-Smook A, Stockbrügger RW, Brummer R-JM. Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls. EAur J Clin Nutr . 2000;54:514-521.

Harless W, Crowell E, Abraham J. Anemia and neutropenia associated with copper deficiency of unclear etiology. Am J Hematol . 2006;81(7):546-9.

Huff JD, Keung YK, Thakuri M, Beaty MW, Hurd DD, Owen J, Molnar I. Copper deficiency causes reversible myelodysplasia. Am J Hematol . 2007;82(7):625-30.

Kumar N, Butz JA, Burritt MF. Clinical significance of the laboratory determination of low serum copper in adults. Clin Chem Lab Med . 2007;45(10):1402-10.

Lein D, Lichtmannegger J, Heinzmann U, Summer KH. Dissolution of copper-rich granules in hepatic lysosomes by D-penicillamine prevents the development of fulminant hepatitis in Long-Evans cinnamon rats. J Hepatol . 2000;32(2):193-201.

Mahabir S, Spitz MR, Barrera SL, Beaver SH, Etzel C, Forman MR. Dietary zinc, copper and selenium, and risk of lung cancer. Int J Cancer . 2007;120(5):1108-15.

Milanino R, Marrella M, Crivellente F, Benoni G, Cuzzolin L. Nutritional supplementation with copper in the rat. Effects on adjuvant arthritis development and on some in vivo- and ex vivo-markers of blood neutrophils. Inflamm Res . 2000;49(5):214-223.

Nagano T, Toyoda T, Tanabe H, et al., Clinical features of hematological disorders caused by copper deficiency during long-term enteral nutrition. Intern Med . 2005;44(6):554-9.

Richmond SJ, Brown SR, Campion PD, Porter AJ, Moffett JA, Jackson DA, Featherstone VA, Taylor AJ. Therapeutic effects of magnetic and copper bracelets in osteoarthritis: a randomised placebo-controlled crossover trial. Complement Ther Med . 2009 Oct-Dec;17(5-6):249-56.

Rottkamp CA, Nunomura A, Raina AK, Sayre LM, Perry G, Smith MA. Oxidative stress, antioxidants, and Alzheimer’s disease. Alzheimer Disease Assoc Disorders . 2000;14(Suppl 1):S62-S66.

Strause L, Saltman P, Smith KT, et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr . 1994;124:1060-4.

Tamura T, Turnlund JR. Effect of long-term, high-copper intake on the concentrations of plasma homocysteine and B vitamins in young men. Nutrition . 2004;20(9):757-9.

Thomson SW, Heimburger DC, Cornwell PE, et al. Correlates of total plasma homocysteine: folic acid, copper, and cervical dysplasia. Nutrition . 2000;16(6):411-416.

Turnlund, J. R., Keyes, W. R., Kim, S. K., and Domek, J. M. Long-term high copper intake: effects on copper absorption, retention, and homeostasis in men. Am J Clin Nutr . 2005;81(4):822-828.

RX Clinical Pathway Engine

Continue through a complete learning pathway

Move from understanding the topic to symptoms, tests, treatment, medicines, monitoring, and prevention.

Search the complete library
  1. Understand the condition Begin with the essential facts and a clear explanation of the topic.
  2. Recognize symptoms Learn common symptoms, signs, and patterns of presentation.
  3. Know when to seek help Review urgent warning signs and when professional assessment may be needed.
  4. Understand causes and risks Explore causes, risk factors, mechanisms, and contributing conditions.
  5. Explore tests and diagnosis Learn how clinicians assess the condition and which investigations may be discussed.
  6. Learn treatment approaches Review general treatment categories and management principles.
  7. Understand medicines safely Continue to medicine education, uses, precautions, and monitoring.
  8. Plan monitoring and follow-up Understand monitoring, complications, rehabilitation, and follow-up learning.
  9. Review prevention and self-care Explore prevention, healthy routines, and questions to discuss with a clinician.

Conditions & Diseases

Background, symptoms, causes, diagnosis, and care.

Explore this library

Tests & Investigations

Laboratory, imaging, screening, and diagnostic education.

Explore this library

Medicines

Uses, safety, monitoring, and related medicine knowledge.

Explore this library

Cancer Knowledge

Cancer types, screening, oncology, and treatment education.

Explore this library
Doctor visit helper

Prepare before seeing a doctor

A simple rural-patient checklist to help you explain symptoms clearly, ask better questions, and avoid unsafe self-treatment.

Safety note: This is not a prescription or diagnosis. For severe symptoms, pregnancy danger signs, children with serious illness, chest pain, breathing difficulty, stroke-like weakness, or major injury, seek urgent care.

Which doctor may help?

Start with a registered doctor or the nearest qualified health center.

What to tell the doctor

  • Write when the problem started and how it changed.
  • Bring old prescriptions, investigation reports, and current medicines.
  • Write allergies, pregnancy status, diabetes, kidney/liver disease, and major past illnesses.
  • Bring one family member if the patient is weak, elderly, confused, or a child.

Questions to ask

  • What is the most likely cause of my symptoms?
  • Which danger signs mean I should go to hospital quickly?
  • Which tests are necessary now, and which can wait?
  • How should I take medicines safely and what side effects should I watch for?
  • When should I come for follow-up?

Tests to discuss

  • Vital signs: temperature, pulse, blood pressure, oxygen saturation
  • Basic physical examination by a clinician
  • CBC, urine test, blood sugar, or imaging only when clinically needed

Avoid these mistakes

  • Do not use antibiotics, steroid tablets/injections, or strong painkillers without proper medical advice.
  • Do not hide pregnancy, kidney disease, ulcer, allergy, or blood thinner use.
  • Do not delay emergency care when danger signs are present.

Medicine safety and first-aid guide

This section is for patient education only. It does not replace a doctor, pharmacist, or emergency care.

Safe first steps

  • Drink safe fluids and monitor temperature.
  • In dengue-prone areas, discuss CBC and platelet count when fever persists or warning signs appear.
  • Use tepid sponging for high fever discomfort; avoid ice-cold bathing.

OTC medicine safety

  • For fever, common fever medicine may be discussed with a clinician or pharmacist.
  • Avoid aspirin/ibuprofen-like medicines in suspected dengue unless a doctor says it is safe.

Avoid these mistakes

  • Do not start antibiotics without a proper medical decision.
  • Do not use steroid tablets or injections casually for quick relief.
  • Do not delay emergency care because of home remedies.

Get urgent help if

  • Fever with breathing difficulty, confusion, repeated vomiting, bleeding, severe weakness, stiff neck, or dehydration needs urgent care.
Medicine names, dose, and timing must be decided by a qualified clinician or pharmacist after checking age, pregnancy, allergy, other diseases, and current medicines.

For rural patients and family caregivers

Patient health record and symptom diary

Write your symptoms, medicines already taken, test results, and questions before visiting a doctor. This note stays on your device unless you print or copy it.

Doctor to discuss: Doctor / qualified healthcare provider
Tests to discuss with doctor
  • Basic vital signs: temperature, pulse, blood pressure, oxygen level if needed
  • Relevant blood, urine, imaging, or specialist tests only after clinical assessment
Questions to ask
  • What is the most likely cause of my symptoms?
  • Which warning signs mean I should go to emergency care?
  • Which tests are really needed now?
  • Which medicines are safe for my age, pregnancy status, allergy, kidney/liver/stomach condition, and current medicines?

Emergency warning signs such as chest pain, severe breathing difficulty, sudden weakness, confusion, severe dehydration, major injury, or loss of bladder/bowel control need urgent medical care. Do not wait for online information.

Safe pathway to proper treatment

Care roadmap for: Copper – Uses, Indications, Dosage, Interactions

Use this simple roadmap to understand the next safe steps. It is educational and does not replace examination by a doctor.

Go to emergency care if you notice:
  • Severe or rapidly worsening symptoms
  • Breathing difficulty, chest pain, fainting, confusion, severe weakness, major injury, or severe dehydration
Doctor / service to discuss: Qualified healthcare provider; specialist depends on symptoms and examination.
  1. Step 1

    Check danger signs first

    If danger signs are present, seek emergency care and do not wait for online information.

  2. Step 2

    Record the symptom story

    Write when symptoms started, severity, medicines already taken, allergies, pregnancy status, and test results.

  3. Step 3

    Visit a qualified clinician

    A doctor, nurse, or qualified healthcare provider can examine you and decide which tests or treatment are needed.

  4. Step 4

    Do only useful tests

    Do tests after clinical assessment. Avoid unnecessary tests, random antibiotics, or repeated medicines without diagnosis.

  5. Step 5

    Follow up and return early if worse

    If symptoms worsen, new warning signs appear, or treatment is not helping, return for review quickly.

Rural patient practical tips
  • Take a written symptom diary and all previous prescriptions/test reports.
  • Do not hide medicines already taken, even herbal or over-the-counter medicines.
  • Ask which warning signs mean urgent referral to hospital.

This roadmap is for education. A real diagnosis and treatment plan requires history, examination, and clinical judgment.