Disease A-Z Library

Rx Neurology (A – Z)

Browse plain-English disease and condition guides, including symptoms, causes, diagnosis, treatment options, prevention, and when to seek medical care.

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Diseases A-Z

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Disease A-Z Library

Spastic Quadriparesis Syndrome

Spastic quadriparesis syndrome means weakness in all four limbs with increased muscle tone (stiff, tight muscles) because the upper motor neuron (UMN) system is damaged. The...

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Neurolipomatosis

Neurolipomatosis means there is an overgrowth of normal fat and fibrous tissue inside a peripheral nerve. The nerve becomes thick, bulky, and sometimes feels like a...

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Acute Type M3 Myeloid Leukemia

Acute type M3 myeloid leukemia is a fast-growing blood cancer where many immature white cells called promyelocytes build up in the bone marrow and blood. These...

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Acute Haemorrhagic Leucoencephalitis (AHLE)

Acute haemorrhagic leucoencephalitis (AHLE)—also called Hurst disease, Weston Hurst syndrome, acute haemorrhagic encephalomyelitis (AHEM)—is a very rare, hyper-acute inflammation of the brain’s white matter. It often...

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Acute Flaccid Myelitis (AFM)

Acute flaccid myelitis (AFM) is a sudden illness that damages the gray matter of the spinal cord, especially the front (anterior horn) cells that control muscles....

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Sjögren–Larsson Syndrome

Sjögren–Larsson syndrome is a rare, inherited disorder that affects both the skin and the nervous system. It arises because of a deficiency of the enzyme fatty...

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Progressive Supranuclear Palsy

Progressive Supranuclear Palsy (PSP) is a rare, progressive neurodegenerative disorder characterized by the abnormal accumulation of tau protein in certain brain regions, leading to widespread neuronal...

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Abducens Nerve Palsy

Abducens nerve palsy is a condition in which the sixth cranial nerve (the abducens nerve) does not function properly, leading to weakness or paralysis of the...

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Mixed Sensory-Autonomic Ganglionopathy

Mixed sensory-autonomic ganglionopathy (MSAG) is a rare disorder in which both sensory and autonomic ganglia—the nerve cell clusters responsible for transmitting sensory information (touch, pain, temperature)...

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Small-Fiber Sensory Ganglionopathy

Small-fiber sensory ganglionopathy (SFSG) is a rare disorder characterized by selective injury to the cell bodies (ganglia) of the small-diameter sensory neurons in the dorsal root...

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Sarcoidosis-Related Sensory Neuropathy

Sarcoidosis-related sensory neuropathy is a form of peripheral nerve damage that arises as a complication of sarcoidosis, a multisystem granulomatous disease. In sarcoidosis, clusters of inflammatory...

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POEMS-Associated Neuropathy

POEMS syndrome is a rare multisystem disorder caused by an underlying plasma cell disorder. The name “POEMS” stands for Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, and Skin...

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