Budd–Chiari Syndrome
Budd–Chiari syndrome means the blood leaving your liver through the hepatic veins (and sometimes the nearby inferior vena cava) is blocked. The blockage is usually a blood clot (primary BCS). Less ...
Rx Blood, Metabolism, and Infectious Diseases (A – Z)
Bubonic Plague
Bubonic plague is a severe bacterial infection caused by Yersinia pestis. It usually spreads to people through the bite of infected fleas that live on wild rodents (like rats, squirrels, prairie ...
Bruton Tyrosine Kinase (BTK) Deficiency
Bruton tyrosine kinase (BTK) deficiency is a rare, inherited immune disorder. It mainly affects boys. The body cannot make mature B lymphocytes (B cells), the white blood cells that produce ...
Bruton Agammaglobulinemia Tyrosine Kinase Deficiency
Bruton agammaglobulinemia tyrosine kinase deficiency is a genetic condition that mainly affects boys. A change (mutation) in a gene on the X chromosome called BTK (Bruton’s tyrosine kinase) stops B ...
X-Linked Recessive Agammaglobulinemia
X-Linked Recessive Agammaglobulinemia is a rare genetic condition that mainly affects boys and stops the body from making antibodies. Antibodies are proteins that help you fight germs. In XLA, a ...
Bruton-Type Agammaglobulinemia
Bruton-type agammaglobulinemia is a genetic immune system disease in which the body cannot make mature B-cells and, therefore, makes almost no antibodies (immunoglobulins). This happens because ...
Monoamine Oxidase A Deficiency
Monoamine oxidase A deficiency is a very rare genetic condition that mostly affects boys and men. People with this condition have lower activity of an enzyme called monoamine oxidase A (MAO-A). This ...
Undulant Fever (Human Brucellosis)
Undulant fever—also called brucellosis or Malta fever—is a bacterial infection you can get from contact with infected animals or from eating or drinking unpasteurized milk, cheese, or undercooked ...
Maltese Fever
Maltese fever is an infection in humans caused by Brucella bacteria. These germs live mainly in animals such as goats, sheep, cows, pigs, and dogs. People get infected when they drink raw ...
Brucellosis
Brucellosis is an infection you get from Brucella bacteria. People are usually infected by unpasteurized milk or dairy, or by touching infected animals or animal fluids without protection. It can ...
Sabia Hemorrhagic Fever (Sabiá Virus Disease)
Sabiá hemorrhagic fever is a rare but severe viral illness caused by the Sabiá virus, a New World mammarenavirus (family Arenaviridae). It can lead to high fever, bleeding problems, low platelets, ...
Brain Monoamine Vesicular Transport Disease (VMAT2 Deficiency)
Brain monoamine vesicular transport disease is the rare genetic condition also called brain dopamine–serotonin vesicular transport disease, VMAT2 deficiency, or PKDYS2, caused by biallelic pathogenic ...
Brain Dopamine-Serotonin Vesicular Transport Disease
Brain dopamine-serotonin vesicular transport disease is a very rare genetic condition where a tiny “transport pump” in brain cells—called VMAT2—does not work well. VMAT2 normally packs dopamine and ...
Lame Sickness
Lame Sickness is a rare but dangerous illness. It happens when a nerve poison (toxin) made by Clostridium botulinum blocks signals from nerves to muscles. Muscles then become weak and floppy. ...
Infection Caused by Clostridium Botulinum
Botulism is a rare but very serious illness caused by a nerve poison (botulinum neurotoxin) made by the bacterium Clostridium botulinum. The toxin blocks nerve signals to muscles. That makes muscles ...
Botulism Poisoning
Botulism is a rare but very serious kind of food-, wound-, or gut-related poisoning. It happens when a nerve poison (called botulinum toxin) gets into your body. This poison is made by bacteria named ...
Botulism
Botulism is a rare but very serious poisoning of the nerves. It happens when a powerful toxin (poison) made by Clostridium botulinum and a few related bacteria gets into the body. The toxin blocks ...
Connective Tissue Disorder due to Lysyl Hydroxylase-3 Deficiency (PLOD3-Related Disorder)
Connective tissue disorder due to lysyl hydroxylase-3 deficiency (PLOD3-related disorder) is a rare genetic disease that affects the body’s collagen—the “scaffolding” protein that gives strength and ...
Machupo Hemorrhagic Fever
Machupo hemorrhagic fever is a severe viral illness that affects the whole body. The virus is called Machupo virus, an arenavirus. People usually get infected after breathing in tiny particles from ...
Bolivian Hemorrhagic Fever (BHF)
Bolivian hemorrhagic fever is a severe viral illness that happens in parts of Bolivia. The virus that causes it is called Machupo virus. This virus belongs to the arenavirus family, the same broad ...
