An internal urethral sphincter stricture refers to the narrowing or tightening of the internal urethral sphincter, which is a muscle responsible for controlling the release of urine from the bladder through the urethra. The sphincter works to keep urine in the bladder until you are ready to urinate. When this sphincter becomes damaged or narrowed, it can lead to difficulty urinating, incomplete bladder emptying, or other urinary problems.

Pathophysiology

  1. Structure:
    The internal urethral sphincter is made up of smooth muscle and is located at the base of the bladder, where the urethra begins. It helps control the passage of urine out of the bladder. This sphincter works in tandem with the external urethral sphincter, which is a voluntary muscle.
  2. Blood Supply:
    The blood supply to the urethra and surrounding structures comes from branches of the internal iliac artery, primarily the inferior vesical artery. These blood vessels provide oxygen and nutrients necessary for the proper function of the sphincter.
  3. Nerve Supply:
    The internal urethral sphincter is controlled by the autonomic nervous system. The sympathetic nerves play a crucial role in contracting the sphincter to hold urine, while the parasympathetic system helps relax it during urination. Damage to these nerves can impair sphincter function.

Types of Internal Urethral Sphincter Stricture

Internal urethral sphincter stricture can be classified into several types based on the cause and location of the narrowing:

  1. Congenital Stricture: Present at birth, often due to abnormal development of the urethra or sphincter.
  2. Acquired Stricture: Develops over time due to injury, inflammation, or scarring.
  3. Traumatic Stricture: Resulting from physical trauma to the urethra or pelvic area.
  4. Inflammatory Stricture: Caused by infections, inflammation, or autoimmune conditions that lead to swelling and scarring.
  5. Post-surgical Stricture: Occurs after surgery near the urethra, such as prostate surgery.
  6. Obstructive Stricture: When the sphincter becomes so tight that it obstructs the flow of urine.

Causes of Internal Urethral Sphincter Stricture

  1. Infections: Urinary tract infections (UTIs) or sexually transmitted infections can cause scarring.
  2. Trauma: Injury to the urethra during surgery, catheterization, or accidents.
  3. Chronic Prostatitis: Inflammation of the prostate that affects the urethra.
  4. Radiation Therapy: Treatment for prostate or pelvic cancers can damage the sphincter.
  5. Pelvic Surgery: Surgeries involving the bladder, prostate, or uterus can lead to strictures.
  6. Urinary Retention: Chronic inability to fully empty the bladder, leading to increased pressure and stricture formation.
  7. Bladder Neck Surgery: Procedures that involve the bladder neck may cause scarring and narrowing of the sphincter.
  8. Benign Prostatic Hyperplasia (BPH): Enlargement of the prostate can affect the sphincter.
  9. Recurrent UTIs: Frequent infections may cause long-term scarring of the urethra.
  10. Traumatic Catheterization: Improper or repeated use of urinary catheters can damage the sphincter.
  11. Nerve Damage: Damage to the nerves controlling the sphincter can lead to dysfunction and stricture formation.
  12. Aging: As people age, the tissues around the urethra can weaken and develop scarring.
  13. Congenital Defects: Some people are born with abnormalities in the urethra or sphincter.
  14. Systemic Conditions: Conditions like diabetes can affect the function of the sphincter.
  15. Spinal Cord Injuries: Injuries to the spinal cord can interfere with nerve signals to the sphincter.
  16. Sexual Activity: Injury or repeated trauma from sexual activity can contribute to stricture development.
  17. Bladder Infections: Long-term bladder infections can cause scarring in the urethra.
  18. Inflammatory Diseases: Conditions like chronic cystitis or urethritis can result in scarring and strictures.
  19. Hypospadias: A congenital condition where the urethra develops abnormally, leading to strictures.
  20. Surgical Scarring: Previous surgeries, such as for bladder or prostate issues, can lead to scar tissue formation.

Symptoms of Internal Urethral Sphincter Stricture

  1. Difficulty Urinating: Trouble starting or maintaining a urine stream.
  2. Weak Urine Stream: Urine comes out in a weak or interrupted stream.
  3. Increased Urinary Frequency: Feeling the need to urinate more often than usual.
  4. Urgency to Urinate: A sudden, intense urge to urinate.
  5. Incomplete Bladder Emptying: Feeling like the bladder is not fully emptied after urination.
  6. Painful Urination: Discomfort or pain when urinating.
  7. Nocturia: Waking up multiple times during the night to urinate.
  8. Urinary Retention: Inability to completely empty the bladder, leading to retention of urine.
  9. Straining to Urinate: Putting in extra effort to start urinating.
  10. Dribbling After Urination: Leaking small amounts of urine after finishing urination.
  11. Blood in Urine: Hematuria or blood appearing in the urine.
  12. Bladder Spasms: Involuntary bladder contractions that cause discomfort.
  13. Pelvic Pain: Pain in the lower abdomen or pelvic area.
  14. Frequent UTIs: Recurring urinary tract infections due to incomplete bladder emptying.
  15. Urgency Incontinence: Urine leakage due to the urgent need to urinate.
  16. Pain During Sexual Intercourse: Discomfort or pain during sexual activity due to urinary issues.
  17. Erectile Dysfunction: Difficulty in achieving or maintaining an erection, linked to urinary and sphincter dysfunction.
  18. Reduced Urinary Flow: A noticeable decrease in the amount of urine being passed.
  19. Pressure or Fullness in the Abdomen: A feeling of fullness or pressure from retained urine.
  20. Foul-smelling Urine: An unusual, unpleasant smell in the urine.

Diagnostic Tests for Internal Urethral Sphincter Stricture

  1. Urinalysis: To check for infections or other abnormalities in the urine.
  2. Ultrasound: To visualize the bladder and urethra and check for structural issues.
  3. Cystoscopy: A procedure where a scope is inserted into the urethra to view the interior and detect strictures.
  4. Uroflowmetry: A test to measure the flow rate and volume of urine during urination.
  5. Post-Void Residual Volume Test: Measures the amount of urine left in the bladder after urination.
  6. X-rays with Contrast: Used to create images of the urinary system and detect abnormalities.
  7. Magnetic Resonance Urethrography (MRU): A non-invasive imaging test to evaluate the urethra.
  8. Urethral Pressure Profilometry: Measures the pressure within the urethra and sphincter function.
  9. Computed Tomography (CT) Scan: Provides detailed images of the bladder and urethra.
  10. Voiding Cystourethrogram: An imaging test to examine the bladder and urethra while urinating.
  11. Bladder Diary: A record of fluid intake, urination frequency, and symptoms for assessment.
  12. Urodynamics: Measures the function and pressure in the bladder and urethra during filling and voiding.
  13. Electromyography (EMG): Used to assess the function of the muscles controlling the bladder and urethra.
  14. Blood Tests: To check kidney function and rule out systemic infections.
  15. Urinary Flow Rate Measurement: A simple test to check how fast urine is flowing.
  16. Cystogram: An X-ray of the bladder and urethra after filling the bladder with a contrast dye.
  17. Cystometrogram: Measures the pressure in the bladder as it fills and empties.
  18. Bladder Ultrasound: To detect any urine retention or abnormalities in the bladder.
  19. Cytology: To detect cancerous cells in the urinary system.
  20. Biopsy: A small tissue sample taken from the urethra or bladder for further analysis.

Non-Pharmacological Treatments for Internal Urethral Sphincter Stricture

  1. Pelvic Floor Exercises: Strengthening pelvic muscles to help control urine flow.
  2. Biofeedback Therapy: A method to train the brain to control sphincter function.
  3. Bladder Training: Gradually increasing the time between urinations to improve bladder control.
  4. Timed Voiding: Emptying the bladder at scheduled intervals to avoid retention.
  5. Fluid Management: Adjusting fluid intake to manage bladder function.
  6. Catheterization: Using a catheter to drain the bladder when necessary.
  7. Electrical Stimulation: Using electrical impulses to strengthen the muscles controlling urination.
  8. Dietary Changes: Avoiding bladder irritants like caffeine and alcohol.
  9. Physical Therapy: To help with pelvic muscle relaxation and coordination.
  10. Bladder Emptying Techniques: Methods to help ensure the bladder is fully emptied.
  11. Psychological Counseling: For managing anxiety or stress related to urinary issues.
  12. Weight Management: Reducing pressure on the bladder by maintaining a healthy weight.
  13. Avoiding Constipation: Preventing pressure on the bladder by managing bowel movements.
  14. Kegel Exercises: Strengthening pelvic muscles to improve control over urination.
  15. Urethral Dilation: Gradual dilation of the urethra to reduce stricture.
  16. Biofeedback: Training the body to recognize when to contract and relax the sphincter.
  17. Dietary Fiber: Ensuring proper bowel function to reduce strain on the bladder.
  18. Hydration: Drinking adequate water to prevent urinary tract infections and ensure regular urination.
  19. Smoking Cessation: Quitting smoking to reduce irritation in the urinary tract.
  20. Avoiding Tight Clothing: Wearing loose clothing to avoid unnecessary pressure on the bladder and urethra.
  21. Yoga: Certain yoga poses help strengthen pelvic muscles and relieve pressure on the bladder.
  22. Acupuncture: Alternative therapy to alleviate urinary symptoms and improve function.
  23. Aromatherapy: Use of essential oils for stress relief and improving bladder function.
  24. Chiropractic Care: Addressing musculoskeletal issues that may affect bladder control.
  25. Manual Therapy: Techniques to release tension in the pelvic area.
  26. Massage: Pelvic massage to improve blood flow and muscle relaxation.
  27. Mindfulness Techniques: Stress management through mindfulness and meditation.
  28. Lymphatic Drainage: Helping remove excess fluid and reduce swelling around the urethra.
  29. Herbal Remedies: Use of specific herbs known to promote bladder health.
  30. Lifestyle Changes: Modifying daily habits to prevent aggravation of symptoms.

Drugs for Internal Urethral Sphincter Stricture

  1. Alpha-blockers: Medications like tamsulosin to relax the bladder neck and sphincter.
  2. Antibiotics: Used to treat infections that might contribute to the stricture.
  3. Corticosteroids: For reducing inflammation around the sphincter.
  4. 5-alpha reductase inhibitors: Drugs like finasteride that help with prostate-related stricture.
  5. Antispasmodics: To relax bladder muscles and reduce spasms.
  6. Anti-inflammatory Drugs: For managing inflammation in the urethra.
  7. Local Anesthetics: For temporary relief of pain during urination.
  8. Diuretics: To reduce fluid retention and improve urine flow.
  9. Hormonal Therapy: To address hormonal imbalances contributing to the stricture.
  10. Pain Relievers: Over-the-counter painkillers like ibuprofen to reduce discomfort.
  11. Nerve Blockers: For relieving nerve pain related to sphincter dysfunction.
  12. Prostaglandins: To promote relaxation of smooth muscles.
  13. Vasodilators: To increase blood flow to the bladder and sphincter area.
  14. Botulinum Toxin: Injection to relax overactive bladder muscles and sphincter.
  15. Antidepressants: To address emotional issues and improve quality of life.
  16. Aphrodisiacs: For addressing erectile dysfunction associated with stricture.
  17. Anticholinergics: For managing urgency and frequent urination.
  18. Immunosuppressive Drugs: To treat autoimmune-related causes of the stricture.
  19. Herbal Supplements: Non-prescription herbal treatments for bladder health.
  20. Opiates: For managing severe pain associated with strictures.

Surgeries for Internal Urethral Sphincter Stricture

  1. Urethral Dilation: Stretching the narrowed area to widen the urethra.
  2. Urethrotomy: A surgical procedure to cut through the stricture and relieve obstruction.
  3. Urethral Reconstruction: Surgery to rebuild or repair the damaged portion of the urethra.
  4. Bladder Neck Suspension: Surgery to lift the bladder neck for better control.
  5. Prostatectomy: Removal of part of the prostate to relieve pressure on the urethra.
  6. Bladder Augmentation: Adding tissue to the bladder to help improve function.
  7. Urethral Stent Placement: Inserting a stent to hold the urethra open.
  8. Sphincteroplasty: Repair or reconstruction of the urethral sphincter to improve function.
  9. Laser Surgery: Using a laser to remove scar tissue causing the stricture.
  10. Diverting Urostomy: Creating a new pathway for urine if the stricture is severe.

Preventive Measures for Internal Urethral Sphincter Stricture

  1. Regular Urination: Don’t hold urine for long periods to prevent strain on the bladder.
  2. Proper Catheter Use: Ensuring catheters are used correctly to prevent injury.
  3. Treat Infections Promptly: Address UTIs and other infections quickly to prevent scarring.
  4. Avoid Smoking: Smoking can irritate the urinary tract, leading to problems.
  5. Healthy Diet: Eating foods that support bladder health and reduce irritation.
  6. Hydration: Drink plenty of fluids to flush out the urinary system.
  7. Exercise: Regular physical activity helps maintain bladder function and pelvic health.
  8. Avoid Bladder Irritants: Limit caffeine, alcohol, and acidic foods that can irritate the bladder.
  9. Manage Chronic Conditions: Keep conditions like diabetes under control to avoid urinary complications.
  10. Monitor Urinary Symptoms: Keep track of changes in urination and consult a doctor if necessary.

When to See a Doctor

  • Difficulty Urinating: If you’re struggling to urinate or have a weak stream.
  • Painful Urination: If urination becomes painful or uncomfortable.
  • Blood in Urine: If you notice blood in your urine, seek medical attention immediately.
  • Urinary Retention: If you’re unable to fully empty your bladder.
  • Persistent Symptoms: If symptoms like frequent UTIs or urgency persist.

This detailed yet accessible guide aims to provide clear and practical information about internal urethral sphincter strictures, covering causes, symptoms, diagnostic tests, and treatment options. Whether you’re a patient, caregiver, or healthcare provider, understanding this condition is essential for improving bladder health and urinary function.

 

 

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.

 

 

      RxHarun
      Logo
      Register New Account