Corpus Cavernosum Cancer

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist
1 View
Rx Urology

The corpus cavernosum is a part of the male anatomy located within the penis. It is primarily responsible for the penis’ ability to become erect. Cancer in the corpus cavernosum is rare but can cause significant health problems if left untreated. Let’s break down this condition in a simple, easy-to-understand manner, covering everything from its pathophysiology to treatments.

Corpus cavernosum cancer refers to cancer that develops in the cavernous tissue of the penis. This tissue is composed of two columns of erectile tissue that become engorged with blood during arousal, causing the penis to become erect. Cancer in this area can be quite serious, but it is very rare compared to other forms of cancer.

Pathophysiology of Corpus Cavernosum Cancer

Structure of Corpus Cavernosum

  • The penis consists of three main columns of erectile tissue: two corpora cavernosa and one corpus spongiosum.
  • The corpora cavernosa are the two larger, erectile tissues located on either side of the penis.
  • These tissues contain spaces that fill with blood during sexual arousal, causing an erection.

Blood Supply

  • The blood supply to the corpora cavernosa comes from the penile arteries.
  • These arteries ensure that there is a steady flow of blood, which is necessary for the erectile function of the penis.

Nerve Supply

  • The nerve supply comes from the autonomic nervous system, which controls involuntary functions. This system is responsible for the sensation and control of erections.

Types of Corpus Cavernosum Cancer

There are several types of cancers that can affect the corpus cavernosum, including:

  • Squamous Cell Carcinoma: The most common type of penile cancer, often starting in the skin cells of the penis.
  • Melanoma: A rare form of cancer that originates in the pigment-producing cells of the skin.
  • Sarcoma: A type of cancer that develops in connective tissues, including muscles and blood vessels in the penis.

Causes of Corpus Cavernosum Cancer

While the exact cause of corpus cavernosum cancer is not fully understood, there are several factors that may increase the risk:

  1. Human Papillomavirus (HPV) infection
  2. Uncircumcised males
  3. Poor hygiene
  4. History of genital warts
  5. Age (more common in older adults)
  6. Smoking
  7. Chronic inflammation in the penis
  8. Weakened immune system
  9. Excessive alcohol consumption
  10. Exposure to carcinogens
  11. Psoriasis treatments that use UV light
  12. Previous cancer treatments like radiation
  13. A family history of cancer
  14. Impaired immune system function
  15. Diabetes
  16. Obesity
  17. Lack of protection during sexual activity
  18. Multiple sexual partners
  19. Exposure to chemical irritants
  20. Chronic ulcers or wounds on the penis

Symptoms of Corpus Cavernosum Cancer

Corpus cavernosum cancer may not show obvious symptoms in its early stages. As the condition progresses, patients might experience:

  1. Painful or tender lumps on the penis
  2. Swelling of the penis
  3. Discharge from the penis
  4. Ulcerations or open sores on the penis
  5. Changes in skin color or texture
  6. Bleeding from the penis
  7. Erectile dysfunction
  8. Painful erections
  9. Inflammation in the groin
  10. Difficulty urinating
  11. Painful ejaculation
  12. Weight loss
  13. Fatigue
  14. Loss of appetite
  15. Pelvic pain
  16. Foul-smelling discharge
  17. Persistent penile rash
  18. Itching or burning sensation on the penis
  19. Hardening of the penis
  20. Enlarged lymph nodes in the groin

Diagnostic Tests for Corpus Cavernosum Cancer

To diagnose corpus cavernosum cancer, a doctor will need to perform various tests:

  1. Physical Examination
  2. Penile Biopsy (a tissue sample taken for lab analysis)
  3. Ultrasound to examine blood flow
  4. MRI Scan for detailed imaging
  5. CT Scan to detect spread of cancer
  6. X-ray for skeletal involvement
  7. Blood Tests (for tumor markers)
  8. Endoscopy to view internal tissues
  9. Lymph Node Biopsy to check for cancer spread
  10. Penile Doppler Ultrasound to assess blood flow
  11. PET Scan to detect any spread of cancer
  12. Colposcopy for abnormal tissue assessment
  13. Chest X-ray to check for lung involvement
  14. Cystoscopy for urethra and bladder examination
  15. Pap Smear for HPV testing
  16. Genetic Testing to check for inherited cancer risks
  17. DNA Testing of tumor cells
  18. Urine Test for signs of infection
  19. Penile Color Doppler to detect blood vessel changes
  20. Bone Scan if cancer has spread to bones

Non-Pharmacological Treatments for Corpus Cavernosum Cancer

Several non-pharmacological treatments can help manage corpus cavernosum cancer or its symptoms:

  1. Surgery (to remove tumors)
  2. Cryotherapy (freezing cancer cells)
  3. Radiation Therapy
  4. Chemotherapy
  5. Immunotherapy
  6. Penile Rehabilitation Therapy
  7. Psychosocial Counseling (for emotional support)
  8. Dietary Changes (to boost immune health)
  9. Exercise (to maintain overall health)
  10. Massage Therapy
  11. Acupuncture
  12. Physical Therapy
  13. Stress Reduction Techniques (like yoga)
  14. Lifestyle Modifications
  15. Wound Care
  16. Herbal Remedies (under medical supervision)
  17. Vitamin Supplements
  18. Hydrotherapy
  19. Mindfulness Practices
  20. Sleep Hygiene
  21. Therapeutic Touch
  22. Nutritional Support
  23. Support Groups
  24. Palliative Care (for pain management)
  25. Lymphatic Drainage Therapy
  26. Smoking Cessation Programs
  27. Alcohol Reduction Programs
  28. Psychotherapy
  29. Grief Counseling
  30. Peer Support Networks

Medications (Drugs) Used in Corpus Cavernosum Cancer Treatment

Doctors may prescribe medications, including:

  1. Pain relievers (for cancer-related pain)
  2. Antibiotics (to prevent infections)
  3. Chemotherapy drugs like Cisplatin
  4. Immunotherapy drugs such as Keytruda
  5. Targeted therapy drugs (for precision medicine)
  6. Hormone Therapy (in some cases)
  7. Topical chemotherapy creams like 5-FU
  8. Anti-inflammatory drugs
  9. Nerve pain medications
  10. Steroids to reduce inflammation
  11. Antiemetics (for nausea control)
  12. Antibiotic ointments
  13. Alpha-blockers (for erectile dysfunction)
  14. Erectile dysfunction medications like Viagra
  15. Corticosteroids
  16. Immunosuppressive drugs
  17. Blood thinners
  18. Pain patch medications
  19. Anxiolytics (for anxiety relief)
  20. Bone-strengthening drugs (if cancer affects bones)

Surgical Options for Corpus Cavernosum Cancer

Surgery may be necessary to remove the cancer or treat symptoms:

  1. Penectomy (partial or complete removal of the penis)
  2. Lymphadenectomy (removal of affected lymph nodes)
  3. Penile Prosthesis Implantation (for erectile dysfunction)
  4. Laser Surgery (for small tumors)
  5. Microsurgery to remove cancerous tissue
  6. Vascular Surgery to improve blood flow
  7. Pelvic Exenteration (removal of pelvic organs)
  8. Reconstructive Surgery (to restore appearance)
  9. Cryosurgery (freezing cancer cells)
  10. Radiation Surgery (focused radiation on the tumor)

Prevention of Corpus Cavernosum Cancer

Although it’s not always possible to prevent corpus cavernosum cancer, some preventive measures may reduce the risk:

  1. Vaccination against HPV
  2. Good genital hygiene
  3. Quit smoking
  4. Limit alcohol consumption
  5. Practice safe sex
  6. Regular screenings for early cancer detection
  7. Avoid exposure to carcinogens
  8. Healthy diet rich in fruits and vegetables
  9. Maintain a healthy weight
  10. Exercise regularly
  11. Use condoms during sexual activity
  12. Routine doctor check-ups
  13. Manage underlying conditions like diabetes
  14. Genetic testing for cancer risks
  15. Avoid excessive sun exposure
  16. Stress management
  17. Sleep well
  18. Vaccination against hepatitis
  19. Be aware of family history of cancer
  20. Avoid chemical irritants and toxic substances

When to See a Doctor

If you notice any signs of corpus cavernosum cancer, you should consult a healthcare provider. Symptoms like unusual lumps, bleeding, painful erections, or changes in appearance should never be ignored. Early diagnosis can significantly improve treatment outcomes.

 

Authors

The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members

Rx Editorial Board Member and Team Rxharun’s Writers Links

More details about authors, please visit to  Sciprofile.com 

Last Update: January 04, 2025.

Authors Information

 

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.

 

  1. https://pubmed.ncbi.nlm.nih.gov/27887750/
  2. https://pubmed.ncbi.nlm.nih.gov/34175022/
  3. https://pubmed.ncbi.nlm.nih.gov/31573641/
  4. https://pubmed.ncbi.nlm.nih.gov/30571025/
  5. https://www.ncbi.nlm.nih.gov/books/NBK535404/
  6. https://pubmed.ncbi.nlm.nih.gov/15882252/
  7. https://pubmed.ncbi.nlm.nih.gov/29168475/
  8. https://pubmed.ncbi.nlm.nih.gov/34739697/
  9. https://pubmed.ncbi.nlm.nih.gov/31399958/
  10. https://pubmed.ncbi.nlm.nih.gov/38052474/
  11. https://pubmed.ncbi.nlm.nih.gov/29431364/
  12. https://pubmed.ncbi.nlm.nih.gov/27383068/
  13. https://pubmed.ncbi.nlm.nih.gov/26055354/
  14. https://pubmed.ncbi.nlm.nih.gov/38490803/
  15. https://medlineplus.gov/skinconditions.html
  16. https://en.wikipedia.org/wiki/Category:Kidney_diseases
  17. https://kidney.org.au/your-kidneys/what-is-kidney-disease/types-of-kidney-disease
  18. https://www.niddk.nih.gov/health-information/kidney-disease
  19. https://www.kidney.org/kidney-topics/chronic-kidney-disease-ckd
  20. https://www.kidneyfund.org/all-about-kidneys/types-kidney-diseases
  21. https://www.aad.org/about/burden-of-skin-disease
  22. https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
  23. https://www.cdc.gov/niosh/topics/skin/default.html
  24. https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084
  25. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Understanding-Sleep
  26. https://www.cdc.gov/traumaticbraininjury/index.html
  27. https://www.skincancer.org/
  28. https://illnesshacker.com/
  29. https://endinglines.com/
  30. https://www.jaad.org/
  31. https://www.psoriasis.org/about-psoriasis/
  32. https://books.google.com/books?
  33. https://www.niams.nih.gov/health-topics/skin-diseases
  34. https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
  35. https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
  36. https://dermnetnz.org/topics
  37. https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
  38. https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
  39. https://aafa.org/allergies/allergy-symptoms/skin-allergies/
  40. https://www.nibib.nih.gov/
  41. https://rxharun.com/rxharun/rxharun/article-types/skin-care-beauty/skin-diseases-types-symptoms-treatment/
  42. https://www.nei.nih.gov/
  43. https://en.wikipedia.org/wiki/List_of_skin_conditions
  44. https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
  45. https://en.wikipedia.org/wiki/Skin_condition
  46. https://oxfordtreatment.com/
  47. https://www.nidcd.nih.gov/health/
  48. https://consumer.ftc.gov/articles/w
  49. https://www.nccih.nih.gov/health
  50. https://catalog.ninds.nih.gov/
  51. https://www.aarda.org/diseaselist/
  52. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
  53. https://www.nibib.nih.gov/
  54. https://www.nia.nih.gov/health/topics
  55. https://www.nichd.nih.gov/
  56. https://www.nimh.nih.gov/health/topics
  57. https://www.nichd.nih.gov/
  58. https://www.niehs.nih.gov
  59. https://www.nimhd.nih.gov/
  60. https://www.nhlbi.nih.gov/health-topics
  61. https://obssr.od.nih.gov/
  62. https://www.nichd.nih.gov/health/topics
  63. https://rarediseases.info.nih.gov/diseases
  64. https://beta.rarediseases.info.nih.gov/diseases
  65. https://orwh.od.nih.gov/

References

 

You Might Also Like This :

  1. Corpus Cavernosum Necrosis Corpus cavernosum necrosis is a medical condition that affects the penis, particularly the corpora cavernosa, which are two sponge-like structures inside the penis that fill with blood during an erection. The term “necrosis” refers to the death of cells or tissues, and when it affects the corpora cavernosa, it can lead to severe complications, including […]...
  2. Corpus Cavernosum Masses The corpus cavernosum is a vital part of the male anatomy. It refers to two columns of erectile tissue found in the penis. The term corpus cavernosum masses refers to any abnormal growth or enlargement of this tissue, which may affect sexual function and overall health. In this guide, we will delve into the pathophysiology, […]...
  3. Corpus Cavernosum Injury The corpus cavernosum injury refers to damage or trauma to the erectile tissue located inside the penis that is responsible for erection. Understanding this injury, including its causes, symptoms, treatments, and prevention, is essential for men’s health. In this article, we will break down the anatomy, the types, causes, symptoms, diagnostic tests, treatments, surgeries, and […]...
  4. Corpus Cavernosum Polyps Corpus cavernosum polyps are abnormal growths found in the penis, specifically within the corpus cavernosum, which is a sponge-like tissue that fills with blood during an erection. These polyps can affect the functionality of the erectile tissue and, if left untreated, may cause various complications. While rare, it is crucial to understand the pathophysiology, causes, […]...
  5. Corpus Cavernosum Obstruction The corpus cavernosum is a pair of sponge-like tissue structures found inside the penis. These tissues fill with blood to help a man achieve an erection. When there is an obstruction, it means that there is a blockage or restriction that prevents the blood from flowing properly into the corpus cavernosum. This can lead to […]...
  6. Corpus Cavernosum Dysfunction Corpus cavernosum dysfunction refers to problems with the two sponge-like regions of erectile tissue found in the penis. These issues can lead to difficulties in achieving or maintaining an erection, impacting sexual health and overall quality of life. This guide provides detailed descriptions, definitions, causes, symptoms, diagnostic methods, treatments, and preventive measures related to corpus […]...
  7. Corpus Cavernosum Cysts A corpus cavernosum cyst is a rare condition affecting the penis, typically involving a fluid-filled sac in the tissue of the penis. These cysts are usually benign (non-cancerous) and can sometimes cause discomfort or other symptoms. This article will guide you through everything you need to know about corpus cavernosum cysts, including their pathophysiology, causes, […]...
  8. Corpus Cavernosum Pain The corpus cavernosum is a part of the male penis made of spongy tissue that helps with erection. Pain in this area can be caused by various reasons, such as injuries, infections, or conditions affecting blood flow. In this article, we will explain the pain associated with the corpus cavernosum, its causes, symptoms, and the […]...
  9. Corpus Cavernosum Urethra Diseases The corpus cavernosum refers to two sponge-like regions of erectile tissue found in the penis. These structures fill with blood during sexual arousal, causing an erection. The urethra is a tube that carries urine from the bladder out of the body and also transports semen during ejaculation. Diseases affecting these areas can impact sexual function, […]...
  10. Corpus Cavernosum Urethral Disorders The corpus cavernosum and urethra play crucial roles in male reproductive and urinary systems. The corpus cavernosum is erectile tissue in the penis that fills with blood to cause an erection, while the urethra is a tube that carries urine and semen out of the body. Disorders affecting these structures can lead to significant health […]...
  11. Corpus Cavernosum Tumor A corpus cavernosum tumor refers to an abnormal growth or lump that occurs in the corpus cavernosum, which are the two spongy tissues in the penis or clitoris. These tissues are essential for sexual function as they fill with blood during arousal, causing an erection. When a tumor develops here, it can affect blood flow […]...
  12. Corpus Cavernosum Spasms The corpus cavernosum consists of two sponge-like regions of erectile tissue found in the penis. These structures play a crucial role in achieving and maintaining an erection by filling with blood during sexual arousal. Proper functioning of the corpus cavernosum is vital for sexual health and performance. Corpus cavernosum spasms refer to involuntary muscle contractions […]...
  13. Corpus Cavernosum Swelling Corpus cavernosum swelling refers to the enlargement or inflammation of one or both of the two sponge-like regions of erectile tissue found in the penis. Understanding this condition is essential for maintaining sexual health and overall well-being. This guide provides detailed information on corpus cavernosum swelling, including its causes, symptoms, diagnostic methods, treatments, and more, […]...
  14. Corpus Cavernosum Atrophy The corpus cavernosum refers to two sponge-like regions of erectile tissue in the penis. Corpus cavernosum atrophy is the condition where these tissues shrink or weaken. This can lead to erectile dysfunction (ED), decreased penile rigidity, and other sexual health issues. Atrophy means the reduction in size and function of a bodily organ or tissue. […]...
  15. Corpus Callosum Tumors Corpus callosum tumors are growths that develop in the corpus callosum, a structure in the brain that connects the left and right hemispheres. These tumors can vary in type and severity, leading to a range of symptoms and complications. In this article, we’ll explore the types, causes, symptoms, diagnosis, treatments, drugs, surgeries, preventions, and when […]...

To Get Daily Health Newsletter

We don’t spam! Read our privacy policy for more info.

Terms and Conditions of Use
Privacy Policy
Cookie Policy
Editorial Policy
Advertising Policy
EU User Consent Policy
Correction Policy
Citation Policy
Ethics and Logical Policies
About Us
Contact Us
Newsletter
Career
Sitemap
Advertise with us
Editorial Board Members
Review Board Member
Team RxHarun
Web Developers Team
Guest Posts and Sponsored Posts
Request for Board Member
Women Writers
Download Mobile Apps
Follow us on Social Media
© 2012 - 2025; All rights reserved by authors. Powered by Mediarx International LTD, a subsidiary company of Rx Foundation.
RxHarun
Logo