What is Xanthoma Planum?
Xanthoma planum might sound like a complex medical term, but we're here to break it down in simple, plain English. Let's start by explaining what it is and then dive into its types, causes, symptoms, ...
Xanthoma planum might sound like a complex medical term, but we're here to break it down in simple, plain English. Let's start by explaining what it is and then dive into its types, causes, symptoms, ...
Xanthelasma is a mouthful of a word, but it refers to a relatively common and benign skin condition that can affect your eyelids. In simple terms, it involves yellowish patches or bumps that develop ...
Wilson's disease is a rare but serious genetic disorder that affects the body's ability to process copper properly. In this article, we will provide simple explanations for various aspects of ...
Verruciform xanthoma is a rare and benign skin condition that primarily affects the oral cavity and genital region. In this article, we will simplify the complex medical jargon and provide clear, ...
Tuberous xanthoma might sound like a complicated medical term, but we'll break it down into simple language so that everyone can understand. In this article, we will discuss what tuberous xanthoma ...
Sly syndrome, also known as Mucopolysaccharidosis type VII (MPS VII), is a rare genetic disorder that affects the body's ability to break down complex sugars called mucopolysaccharides. In this ...
Scheie syndrome is a rare genetic disorder that affects various body systems. In this article, we'll break down Scheie syndrome in plain English to make it easy to understand. We'll cover its types, ...
Normolipoproteinemic xanthomatosis is a rare genetic disorder that affects how your body processes fats. In this article, we'll break down what this condition is, its types, causes, symptoms, ...
Nodular xanthoma may sound like a complicated medical term, but we're here to break it down into simple language. In this article, we'll explain what nodular xanthoma is, its different types, and ...
Niemann-Pick disease is a rare genetic disorder that affects the body's ability to process lipids, leading to a buildup of harmful substances in various organs. In this comprehensive guide, we will ...
Necrobiosis Lipoidica Diabeticorum (NLD) is a mouthful of a medical term, but we'll break it down into simple language to help you understand it better. This article will explain what NLD is, its ...
Necrobiosis lipoidica is a rare skin condition that affects the lower legs, mainly the shin area. It can be a source of discomfort and concern for those who experience it. In this comprehensive ...
Mucopolysaccharidosis Type VI, also known as MPS VI or Maroteaux-Lamy syndrome, is a rare genetic disorder that affects the body's ability to break down certain complex sugars called ...
Maroteaux-Lamy syndrome, also known as MPS VI (Mucopolysaccharidosis Type VI), is a rare genetic disorder that affects a person's ability to break down complex sugars in their body. In this article, ...
Tuberoeruptive xanthoma is a rare skin condition characterized by the development of yellowish, waxy nodules or bumps on the skin's surface. These growths are caused by the accumulation of fat ...
Traumatic calcinosis cutis is a medical condition that occurs when calcium deposits build up under the skin due to various causes. In simple terms, it's when your skin forms hard, chalky lumps ...
Xanthoma tendinosum is a rare medical condition characterized by the development of fatty deposits, called xanthomas, on tendons throughout the body. These deposits can lead to various health issues ...
Chylomicronemia syndrome, often referred to as hyperchylomicronemia, is a rare metabolic disorder that affects how the body processes fats. This article aims to explain chylomicronemia syndrome in ...
Vogt-Koyanagi-Harada disease is a rare disorder of unknown origin that affects many body systems, including as the eyes, ears, skin, and the covering of the brain and spinal cord (the meninges). The ...
Undifferentiated connective tissue disease (UCTD) is a systemic autoimmune disease. This means the body’s natural immune system does not behave normally. Instead of serving to fight infections ...
Tolosa Hunt syndrome (THS) is a rare condition characterized by painful ophthalmoplegia (paralysis and/or weakness of the eye muscles). Onset can occur at any age. Signs and symptoms include a ...
Immune thrombocytopenic purpura, (ITP) is an autoimmune bleeding disorder. The immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few ...
Sympathetic ophthalmia (SO) is a bilateral diffuse granulomatous uveitis (a kind of inflammation) of both eyes following trauma to one eye. It can leave the patient completely blind. Symptoms may ...
Stiff person syndrome (SPS) is a rare disease of the nervous system. Progressively severe muscle stiffness typically develops in the spine and lower extremities; often beginning very subtly during a ...
Along with symptoms of extensive dryness, other serious complications include profound fatigue, chronic pain, major organ involvement, neuropathies, and lymphomas.As a systemic disease, affecting ...
Scleritis is an inflammation of the sclera (the white outer wall of the eye). Inflammation of the sclera is often linked to autoimmune diseases such as rheumatoid arthritis and systemic lupus ...
Autoimmune Polyendocrine Syndrome Type II (APS-II) is a complex and rare autoimmune disorder that affects multiple endocrine glands in the body. This condition can lead to a variety of symptoms and ...
Schmidt syndrome also known as Polyglandular autoimmune syndrome type 2 is a rare autoimmune syndrome that commonly has the constellation of three diseases: diabetes mellitus type 1, hypothyroidism ...
Retroperitoneal fibrosis is a rare autoimmune related disorder that blocks the tubes (ureters) that carry urine from the kidneys to the bladder. Retroperitoneal fibrosis occurs when extra fibrous ...
Relapsing polychondritis is a rare disease in which cartilage in many areas of the body becomes inflamed. The disease most commonly affects the ears, nose and the airways of the lungs. The cause is ...
Pyoderma gangrenosum is an uncommon, ulcerative cutaneous condition of uncertain etiology (cause). It is associated with systemic autoimmune related diseases in at least 50% of patients who are ...
Progressive Hemifacial Atrophy (PHA) and Parry Romberg syndrome is a rare disorder characterized by slowly progressive deterioration (atrophy) of the skin and soft tissues of half of the face ...
Progesterone dermatitis is a rare condition characterized by a cyclic skin rash which develops premenstrually in women. The condition usually occurs in adulthood after the start of periods ...
Primary sclerosing cholangitis refers to swelling (inflammation), scarring, and destruction of the bile ducts inside and outside of the liver. The cause of this condition is usually unknown. The ...
Dressler’s syndrome is a type of pericarditis, inflammation of the sac surrounding the heart (pericardium). Inflammation associated with Dressler’s syndrome is believed to be an immune system ...
Polymyositis is a rare inflammatory disease that leads to muscle weakness, swelling tenderness, and tissue damage. It is part of a larger group of diseases called myositis. Polymyositis affects the ...
Polymyalgia rheumatica is characterized by muscle pain and stiffness in the neck, shoulder, and hip area. This stiffness, lasting about 30 minutes, is more severe upon waking or after a period of ...
Polyglandular syndromes type I, II, III (PDS) is characterized by sequential or simultaneous deficiencies in the function of several endocrine glands that have a common cause. Etiology (cause, set of ...
Polyarteritis nodosa is a serious autoimmune related blood vessel disease. The small and medium-sized arteries become swollen and damaged. Arteries are the blood vessels that carry oxygen-rich blood ...
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes) – POEMS syndrome is a rare autoimmune related blood disorder that damages your nerves and affects ...
Autoimmune Pernicious Anemia (APA) is a rare medical condition that affects the production of red blood cells in the body. In this article, we will break down the complex aspects of APA into simple, ...
Pemphigus is a group of chronic autoimmune skin diseases characterized by blister formations in the outer layer of the skin and the mucous membranes. Pemphigus vulgaris begins with blister formations ...
Parsonage-Turner syndrome, also called brachial neuritis, is characterized by the sudden onset of shoulder and upper arm pain followed by marked upper arm weakness or atrophy. Individuals may present ...
Peripheral uveitis is an eye condition that affects the outer part of the eye, known as the uvea. It can cause discomfort and vision problems. In this article, we will simplify the complex jargon ...
Pars planitis (peripheral uveitis) is a disease of the eye in which there is inflammation of the pars plana, a small area of tissue next to the iris that is responsible for making aqueous humor (the ...
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease in which red blood cells break down earlier than normal. Persons with this disease have blood cells that are missing a gene called PIG-A. ...
Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. ...
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus Infections, or PANDAS for short, is a condition that affects children and can lead to a range of behavioral and ...
PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus). This term is used to describe a subset of children who have Obsessive Compulsive Disorder (OCD) and/or tic ...
Palindromic rheumatism (PR) is an autoimmune related disease characterized by sudden, multiple, and recurring attacks of joint pain and swelling, typically in the hands and feet. Each episode may ...
Ocular cicatricial pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Other mucosal sites that might be affected include the nasopharnyx, larynx, ...
Neutropenia is an abnormally low number of white blood cells. These cells, which are called neutrophils, help the body fight infection. White blood cells are produced in the bone marrow. They are ...
Neuromyelitis optica – formally known as Devic’s disease, Neuromyelitis optica (NMO) is an uncommon disease syndrome of the central nervous system (CNS) that affects the optic nerves and spinal cord. ...
Neonatal lupus is an uncommon autoimmune disease manifested primarily by cutaneous lupus lesions and/or congenital heart block. Maternal autoantibodies of the Ro/La family are present in ...
Narcolepsy is a chronic brain disorder that involves poor control of sleep-wake cycles. People with narcolepsy experience periods of extreme daytime sleepiness and sudden, irresistible bouts of sleep ...
Myositis means inflammation of the muscles that you use to move your body. An injury, infection, or autoimmune disease can cause it. Two specific kinds are polymyositis and dermatomyositis. ...
Myelin Oligodendrocyte Glycoprotein Antibody Disorder/MOG Antibody Disease (MOGAD) is a recently coined neuro-inflammatory condition that preferentially causes inflammation in the optic nerve but can ...
Multifocal Motor Neuropathy with Conduction Block, often abbreviated as MMNCB, is a rare neurological disorder that affects the peripheral nerves. In simple terms, this condition disrupts the signals ...
Multifocal motor neuropathy (MMN) or multifocal motor neuropathy with conduction block (MMNCB) is a rare neuropathy characterized by progressive, asymmetric muscle weakness and atrophy. Signs and ...
Mucha-Habermann disease may also be called PLEVA (pityriasis lichenoides et varioliformisacuta). It is a skin disease characterized by a recurrent red rash that is itchy and burning. There are red ...
Mixed connective tissue disease (MCTD) has signs and symptoms of a combination of disorders — primarily lupus, scleroderma, and polymyositis. Many people with this uncommon disease also have ...
Microscopic polyangiitis (MPA) is an autoimmune related disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage. The kidneys, lungs, nerves, skin, and joints are ...
Lyme disease, chronic is a late stage of an inflammatory disease caused by Borrelia burgdorferi bacteria and believed to be autoimmune related. It is also called Stage 3, or tertiary, Lyme disease. ...
Linear IgA disease (LAD) is an autoimmune subepidermal (lying beneath or constituting the innermost part of the epidermis) disease that may be idiopathic or drug-induced. Children and adults are ...
Lichen sclerosus is a skin disorder that can affect men, women, or children, but is most common in women. It usually occurs on the vulva (the outer genitalia or sex organ) in women, but sometimes ...
Lambert-Eaton syndrome is an autoimmune disorder in which faulty communication between nerves and muscles leads to muscle weakness. In this syndrome, substances produced by the immune system attack ...
Kawasaki disease is a rare form of vasculitis. Children, usually under the age of 5, have a high fever and red eyes, lips, mouth, a rash and swollen lymph nodes. The disease also affects the heart ...
Juvenile myositis (JM), including Juvenile Dermatomyositis (JDM) and Juvenile Polymyositis (JPM), is a group of rare and life-threatening autoimmune diseases, in which the body’s immune system ...
Juvenile diabetes (Type 1 diabetes) can occur at any age. It is most often diagnosed in children, adolescents, or young adults. Insulin is a hormone produced in the pancreas by special cells ...
Juvenile arthritis is a type of arthritis that happens in children age 16 or younger. It causes joint swelling, pain, stiffness, and loss of motion. It can affect any joint, and in some cases it can ...
Interstitial cystitis (IC) is an autoimmune related condition that causes discomfort or pain in the bladder and a need to urinate frequently and urgently. It is far more common in women than in ...
Inclusion body myositis (IBM) is one of a group of autoimmune related muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation ...
Immune thrombocytopenic purpura, (ITP) is an autoimmune bleeding disorder. The immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few ...
IgG4-related sclerosing disease , also known as IgG4–related systemic disease (IgG4-RSD), hyper-IgG4 disease and IgG4-related disease is an autoimmune disease in which inflammatory cells cause ...
IgA nephropathy is an autoimmune related kidney disorder that occurs when IgA (a protein that helps the body fight infections) settles in the kidneys. After many years, the IgA deposits may cause the ...
Hidradenitis suppurativa (hi-drad-uh-NIE-tis sup-yoo-ruh-TIE-vuh), also known as acne inversa, is a condition that causes small, painful lumps to form under the skin. The lumps usually develop in ...
Pemphigoid gestationis is a rare skin condition that can occur during pregnancy. In this article, we'll break down everything you need to know about pemphigoid gestationis in simple, plain English ...
Herpes gestationis or pemphigoid gestationis (PG) is a bullous (characterized by blistering, such as a second-degree burn) disease developing in association with pregnancy. It is believed to be an ...
Henoch-Schonlein purpura (HSP) is a fairly common autoimmune childhood disorder that may affect adults as well, although less frequently. Children with this condition are often initially seen with ...
Hemolytic anemia autoimmune hemolytic anemia is an autoimmune disorder which causes the premature destruction of red blood cells. A normal red blood cell has a lifespan of approximately 120 days ...
Hashimoto’s thyroiditis is a chronic inflammatory autoimmune thyroid disease in which the immune system attacks and destroys the thyroid gland. The thyroid then produces too little hormone and ...
Wegener's Granulomatosis is a rare autoimmune disease that affects the blood vessels in your body. It can cause various health problems, and understanding its types, causes, symptoms, diagnosis, and ...
Granulomatosis with Polyangiitis (GPA) (formerly called Wegener’s Granulomatosis) is a rare autoimmune disease in which blood vessels and other tissues become inflamed. This inflammation limits blood ...
Goodpasture’s syndrome is a pulmonary-renal syndrome, which is a group of acute illnesses involving the kidneys and lungs. Goodpasture syndrome includes all of the following conditions:...
Glomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged. Glomerulonephritis may be caused by problems with the ...
Giant cell myocarditis is a disease of relatively young, predominantly healthy adults. The patients usually die of heart failure and ventricular arrhythmia unless a cardiac transplantation is ...
Temporal arteritis, also known as giant cell arteritis (GCA), is a medical condition that affects the blood vessels, particularly the arteries near your temples. It's crucial to comprehend the ...
Giant cell arteritis (temporal arteritis) is a disorder that causes inflammation of arteries of the scalp, neck, and arms. It narrows the arteries, which keeps blood from flowing well. Giant cell ...
Fibrosing alveolitis, also known as Idiopathic pulmonary fibrosis (IPF), involves scarring or thickening of the lungs. Doctors do not know what causes idiopathic pulmonary fibrosis (IPF) or why some ...
Evans syndrome is a very rare autoimmune disorder in which the immune system destroys the body’s red blood cells, white blood cells and/or platelets. Affected people often experience thrombocytopenia ...
Essential mixed cryoglobulinemia is often found in people who have a chronic (long-lasting) inflammatory condition, such as an autoimmune disease or hepatitis C. Most people with mixed ...
Erythema nodosum is an inflammatory disorder that involves tender, red bumps (nodules) under the skin. In about half of cases, the exact cause of erythema nodosum is unknown. Some cases may occur ...
Eosinophilic fasciitis is a very rare syndrome in which muscle tissue under the skin, called fascia, becomes swollen and thick. The hands, arms, legs, and feet can swell quickly. The disease may look ...
Eosinophilic esophagitis (EoE) is a newly recognized chronic disease that can be associated with food allergies. It is increasingly being diagnosed in children and adults. EoE is characterized by ...
Dressler’s syndrome is a type of pericarditis, inflammation of the sac surrounding the heart (pericardium). Inflammation associated with Dressler’s syndrome is believed to be an immune system ...
Discoid Lupus, also known as Cutaneous Lupus Erythematosus (CLE), is a chronic autoimmune disease that primarily affects the skin. In this article, we will provide simple, easy-to-understand ...
Neuromyelitis Optica (NMO) is a rare but serious autoimmune disorder that primarily affects the optic nerves and spinal cord. In this article, we will provide simplified explanations of NMO, its ...
Devic’s disease (see neuromyelitis optica) is an autoimmune condition that affects the spinal cord and optic nerves (the nerves that carry information regarding sight from the eye). In Devic disease, ...
Dermatomyositis is an autoimmune muscle disease that involves inflammation and a skin rash. It is a type of inflammatory myopathy. The cause of dermatomyositis is unknown. Experts think it may be due ...
Dermatitis herpetiformis is an extremely itchy rash consisting of bumps and blisters. The rash is chronic, which means it continues over a long period. Dermatitis herpetiformis usually begins in ...
CREST syndrome is an acronym for calcinosis, Raynaud’s phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia. It is a variant of the two groups of scleroderma, localized and systemic. ...
Coxsackie myocarditis is inflammation and weakness of the heart muscle caused by a viral infection (Coxsackie virus) that reaches the heart. Myocarditis can damage the heart muscle causing it to ...
Congenital heart block is a rare complication of pregnancy associated with Sjögren Syndrome (an autoimmune syndrome) that may result in the death of the fetus or infant, or the need for pacing in the ...
Reflex Sympathetic Dystrophy (RSD), also known as Complex Regional Pain Syndrome (CRPS), is a chronic and painful condition that affects the nervous system. In this article, we will provide you with ...
Reflex sympathetic dystrophy also called Complex Regional Pain Syndrome (CRPS) is a chronic pain condition. The key symptom of CRPS is continuous, intense pain out of proportion to the severity of ...
Cold agglutinin disease is a form of autoimmune hemolytic anemia caused by cold-reacting autoantibodies (a type of protein produced by the immune system). Primary cold agglutinin disease is usually ...
Cogan’s syndrome is defined as nonsyphilitic interstitial keratitis (an inflammation of the eye) and bilateral audiovestibular deficits (hearing problems and dizziness). It is more common in ...
Cicatricial pemphigoid (also known as benign mucosal pemphigoid, mucous membrane pemphigoid, or benign mucous membrane pemphigoid) is a rare chronic autoimmune blistering disease characterized by ...
Eosinophilic granulomatosis, also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare autoimmune disease that affects various organs and tissues in the body. In this article, we ...
Churg-Strauss syndrome, also known as allergic granulomatosis or eosinophilic granulomatosis with polyangiitis (EGPA) is an autoimmune disorder characterized by accumulated antibodies, inflammation ...
Chronic recurrent multifocal osteomyelitis (CRMO) Although its definition is still evolving, many doctors and articles describe CRMO as an autoimmune related disease. The origin of this disease ...
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare autoimmune disorder in which there is swelling of nerve roots and destruction of the covering (myelin sheath) over the nerves. This ...