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Aldolase Blood Test – Indications, Procedure, Results

Aldolase is a protein (called an enzyme) that helps break down certain sugars to produce energy. It is found in a high amount of muscle tissue.

A test can be done to measure the amount of aldolase in your blood.

How the Test is Performed

A blood sample is needed.

How to Prepare for the Test

You may be told not to eat or drink anything for 6 hours before the test. Your health care provider will tell you if it is necessary to stop taking any medicines that may interfere with this test. Tell your provider about all the medicines you are taking, both prescription and nonprescription.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.

Why the Test is Performed

This test is done to diagnose or monitor muscle or liver damage.

Other tests that may be ordered to check for liver damage include:

  • ALT (alanine aminotransferase) test
  • AST (aspartate aminotransferase) test

Other tests that may be ordered to check for muscle cell damage include:

  • CPK (creatine phosphokinase) test
  • LDH (lactate dehydrogenase) test

Normal Results

Normal results range between 1.0 to 7.5 units per liter (0.02 to 0.13 microkat/L). There is a slight difference between men and women.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

A higher than normal level may be due to:

  • Damage to skeletal muscles
  • Heart attack
  • Liver, pancreatic, or prostate cancer
  • Muscle disease such as dermatomyositis , muscular dystrophy , polymyositis
  • Swelling and inflammation of the liver ( hepatitis )
  • Viral infection called mononucleosis

Risks

Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling lightheaded
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)

 

 

Frequently Asked Questions

Is this article a replacement for a doctor?

No. It is educational content only. Patients should consult a qualified clinician for diagnosis and treatment.

When should I seek urgent care?

Seek urgent care for severe symptoms, rapidly worsening condition, breathing difficulty, severe pain, neurological changes, or any emergency warning sign.

References

Add references, clinical guidelines, textbooks, journal articles, or trusted medical sources here. You can edit this area later with a custom field named _rx_references.

Written by Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Dr. Md. Harun Ar Rashid, MPH, MD, PhD, is a highly respected medical specialist celebrated for his exceptional clinical expertise and unwavering commitment to patient care. With advanced qualifications including MPH, MD, and PhD, he integrates cutting-edge research with a compassionate approach to medicine, ensuring that every patient receives personalized and effective treatment. His extensive training and hands-on experience enable him to diagnose complex conditions accurately and develop innovative treatment strategies tailored to individual needs. In addition to his clinical practice, Dr. Harun Ar Rashid is dedicated to medical education and research, writing and inventory creative thinking, innovative idea, critical care managementing make in his community to outreach, often participating in initiatives that promote health awareness and advance medical knowledge. His career is a testament to the high standards represented by his credentials, and he continues to contribute significantly to his field, driving improvements in both patient outcomes and healthcare practices. Born and educated in Bangladesh, Dr. Rashid earned his BPT from the University of Dhaka before pursuing postgraduate training internationally. He completed his MD in Internal Medicine at King’s College London, where he developed a special interest in inflammatory arthritis and metabolic bone disease. He then undertook a PhD in Orthopedic Science at the University of Oxford, conducting pioneering research on cytokine signaling pathways in rheumatoid arthritis. Following his doctoral studies, Dr. Rashid returned to clinical work with a fellowship in interventional pain management at the Rx University School of Medicine, refining his skills in image-guided joint injections and minimally invasive pain-relief techniques.