Waldenström Macroglobulinemia РSymptoms, Treatment

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Waldenstr√∂m Macroglobulinemia (WM) is a low-grade B-cell clonal disorder characterized by lymphoplasmacytic bone marrow involvement associated with monoclonal immunoglobulin M (IgM). Although WM remains to be an incurable disease with a heterogeneous clinical course, the recent discovery of mutations in Read More …>>

Polycythemia Vera – Causes, Symptoms, Treatment

Polycythemia Vera¬†is an uncommon¬†myeloproliferative neoplasm¬†in which the¬†bone marrow¬†makes too many¬†red blood cells.¬†It may also result in the overproduction of¬†white blood cells¬†and¬†platelets. Polycythemia, derived from poly (many) and cythemia (cells in the blood), is a condition defined as an abnormal increase Read More …>>

Renal Tubular Acidosis РCauses, Symptoms, Treatment

Renal Tubular Acidosis¬†(RTA) is a medical condition that involves an accumulation of¬†acid¬†in the body due to a failure of the¬†kidneys¬†to appropriately¬†acidify¬†the¬†urine.[1]¬†In¬†renal physiology, when¬†blood¬†is¬†filtered¬†by the kidney, the¬†filtrate¬†passes through the¬†tubules¬†of the¬†nephron, allowing for the exchange of salts, acid equivalents, and other¬†solutes¬†before it Read More …>>

Hyperchloremic Acidosis – Causes, Symptoms, Treatment

Hyperchloremic Acidosis¬†is a form of¬†metabolic acidosis¬†associated with a normal¬†anion gap, a decrease in plasma¬†bicarbonate¬†concentration, and an increase in plasma¬†chloride¬†concentration[rx] (see¬†anion gap¬†for a fuller explanation). Although the plasma anion gap is normal, this condition is often associated with an¬†increased¬†urine anion gap, Read More …>>