Hyoscine Hydrobromide – Uses, Dosage, Side, Effects, Interaction

Last updated: February 8, 2026Reviewed date: February 8, 2026Reading time: 9 min read
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Hyoscine hydrobromide or Scopolamine hydrobromide appears as colorless crystals or white powder or solid. Has no odor. pH (of 5% solution): 4-5.5. Slightly efflorescent in dry air. Bitter, acrid taste. Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade...

For severe symptoms, danger signs, pregnancy, child illness, or sudden worsening, seek urgent medical care.

বাংলা রোগী নোট এখনো যোগ করা হয়নি। পোস্ট এডিটরে “RX Bangla Patient Mode” বক্স থেকে সহজ বাংলা সারাংশ যোগ করুন।

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Article Summary

Hyoscine hydrobromide or Scopolamine hydrobromide appears as colorless crystals or white powder or solid. Has no odor. pH (of 5% solution): 4-5.5. Slightly efflorescent in dry air. Bitter, acrid taste. Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic, and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by...

Key Takeaways

  • This article explains Mechanism Of Actions in simple medical language.
  • This article explains Indications of Hyoscine Hydrobromide in simple medical language.
  • This article explains Contraindications of in simple medical language.
  • This article explains Dosage of Hyoscine Hydrobromide in simple medical language.
Educational health guideWritten for patient understanding and clinical awareness.
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Emergency safety firstUrgent warning signs are highlighted below.

Seek urgent medical care if you notice

These warning signs are general safety guidance. Local emergency numbers and clinical judgment should always come first.

  • Severe symptoms, breathing difficulty, fainting, confusion, or rapidly worsening illness.
  • New weakness, severe pain, high fever, or symptoms after a serious injury.
  • Any symptom that feels urgent, unusual, or unsafe for the patient.
1

Emergency now

Use emergency care for severe, sudden, rapidly worsening, or life-threatening symptoms.

2

See a doctor

Book a professional medical evaluation if symptoms persist, worsen, recur often, affect daily activities, or occur in a high-risk patient.

3

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Use this article to understand possible causes, tests, treatment options, prevention, and questions to ask your clinician.

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Definition

Hyoscine hydrobromide or Scopolamine hydrobromide appears as colorless crystals or white powder or solid. Has no odor. pH (of 5% solution): 4-5.5. Slightly efflorescent in dry air. Bitter, acrid taste.

Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic, and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.

Scopolamine hydrobromide appears as colorless crystals or white powder or solid. Has no odor. pH (of 5% solution): 4-5.5. Slightly efflorescent in dry air. Bitter, acrid taste. (NTP, 1992). Scopolamine hydrobromide (anhydrous) is a hydrobromide that is obtained by the reaction of scopolamine with hydrogen bromide. It has a role as a muscarinic antagonist. It contains scopolamine(1+).

Mechanism Of Actions

Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.

Indications of Hyoscine Hydrobromide

  • Motion sickness, Vertigo
  • Nausea- vomiting, 
  • Travel sickness or motion sickness
  • Vertigo, dizziness, Drowsiness
  • Gastrointestinal tract spasm, Genitourinary spasm
  • IBS (irritable bowel syndrome)
  • Postoperative nausea and vomiting
  • Adjuvants, Anesthesia – Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease the required dosage.
  • Cholinergic Antagonists – Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists.
  • Muscarinic antagonists – Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.
  • Mydriatics agents – that dilate the pupil. They may be either sympathomimetics or parasympatholytics.
  • Since little of the medication crosses the blood-brain barrier, this drug has less effect on the brain and therefore causes a reduced occurrence of the centrally-mediated effects (such as delusions, somnolence, and inhibition of motor functions) which reduce the usefulness of some other anticholinergic drugs.
  • Hyoscine butyl bromide – is still capable of affecting the chemoreceptor trigger zone, due to the lack of a well-developed blood-brain-barrier in the medulla oblongata, which increases the antiemetic effect it produces via local action on the smooth muscle of the gastrointestinal tract.[rx]

Contraindications of

  • Myasthenia gravis, narrow-angle glaucoma, tachycardia, megacolon; hypersensitivity
  • Hypersensitivity to this drug
  • Allergy
  • Depression
  • Porphyria

Dosage of Hyoscine Hydrobromide

Strength: 150mg, 300mg

Dosage by tablet strength

Dosage for hyoscine hydrobromide tablets (150 or 300 micrograms)
Age Which strength? Dose
4 to 9 years 150 micrograms half tablet to 1 tablet
10 to 17 years 150 micrograms 1 tablet to 2 tablets
10 to 17 years 300 micrograms half tablet to 1 tablet
18 years and over 300 micrograms 1 tablet

How to take tablets for excess saliva

  • These tablets are available on prescription only. They can be taken by adults and children aged 12 years or older.
  • The usual dose is 1 tablet (300 micrograms), 3 times a day.

How to use patches for excess saliva

Adults and children aged 10 years or older:

  • Stick a patch to the skin behind the ear.
  • Leave the patch on for 72 hours (3 days).
  • After 72 hours, remove the patch.
  • Stick a new patch behind the other ear.
  • After 72 hours, remove the patch.
  • Repeat the process.

Occasionally a doctor may prescribe patches for a child under the age of 9 years. In this case, they’ll use your child’s weight to work out what size patch to use. They may only need to use half a patch.

How to use patches for travel sickness

Patches are suitable for adults and children aged 10 years or older.

  • Stick a patch to the skin behind the ear 5 to 6 hours before the start of your journey (or the evening before you travel).
  • Remove the patch at the end of your journey.
  • For long journeys, you can keep the patch on for up to 72 hours (3 days).
  • If you’re still traveling after 72 hours, remove the first patch and stick a new patch behind the other ear. You can keep this on for another 72 hours if needed.

Oral
Gastrointestinal tract spasm, Genitourinary spasm

  • Adult: As hyoscine butyl bromide: 20 mg 4 times daily.
  • Child: As hyoscine butyl bromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose.

Oral
Prophylaxis of motion sickness

  • Adult: As hyoscine hydrobromide: Initially, 0.15-0.3 mg 20-30 minutes before a journey, repeat 6 hourly if needed, up to max 3 doses in 24 hours. Max: 0.9 mg daily.
  • Child: As hyoscine hydrobromide: 3-4 years Initially, 0.075 mg, repeated once if needed. Max: 0.15 mg daily; >4-10 years 0.075-0.15 mg, repeat 6 hourly if needed. Max: 0.45 mg daily; >10 years 0.15-0.30 mg, repeat 6 hourly if needed. Max: 0.9 mg daily. All doses should be given 20-30 minutes before a journey.

Oral
IBS (irritable bowel syndrome)

  • Adult: As hyoscine butyl bromide: Initially, 10 mg tid, may increase up to 20 mg 4 times daily if needed.
  • Child: As hyoscine butyl bromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose.

Parenteral
Motion sickness, Nausea, and vomiting, Vertigo

  • Adult: As hyoscine hydrobromide: 0.2 mg as a single dose via IM or SC inj (may also be given via IV inj if required).
  • Child: As hyoscine hydrobromide: 0.006 mg/kg as a single dose via IM or SC inj.

Parenteral
Gastrointestinal tract spasm, Genitourinary spasm

  • Adult: As hyoscine butyl bromide: 20 mg via slow IV or IM inj, may be repeated after 30 minutes if needed. Max: 100 mg daily.

Parenteral
Preoperative medication

  • Adult: As hyoscine hydrobromide: 0.2-0.6 mg given via IV, IM, or SC inj, 30-60 minutes prior to induction of anesthesia.
  • Child: As hyoscine hydrobromide: 0.015 mg/kg given via IM or SC inj, 30-60 minutes prior to induction of anesthesia.

Transdermal
Prophylaxis of motion sickness

  • Adult: As hyoscine hydrobromide patch containing 1.5 mg: Apply 1 patch behind the ear, 4-6 hours before a journey or in the evening before the journey.
  • Child: >10 years Same as adult dose.

Transdermal
Postoperative nausea and vomiting

  • Adult: As hyoscine hydrobromide patch containing 1.5 mg: Apply 1 patch behind the ear on the evening before the surgery or 1 hour before cesarean section. Discard 24 hours after the surgery.
  • Child: >10 years Same as adult dose.

Side Effects Of Hyoscine Hydrobromide

The most common
  • Symptoms of exposure to this chemical include drowsiness, sleepiness, excitement, hallucinations, delirium, psychotic behavior and central nervous system depression.
  • Other symptoms include narcosis, mydriasis, dryness of the mouth and restlessness.
  • Drowsiness
  • Dry mouth
  • Headache
  • Indigestion
  • Depression
  • Skin rashes
  • Restlessness
  • Weight gain
  • Mydriasis, cycloplegia, eye pruritus.
  • Muscle weakness.
  • Urinary retention, pain or burning during urination. সহজ বাংলা: প্রস্রাবে জ্বালা/ব্যথা।" data-rx-term="dysuria" data-rx-definition="Dysuria means pain or burning during urination. সহজ বাংলা: প্রস্রাবে জ্বালা/ব্যথা।">dysuria.
  • Flushing, sweating, dry skin, rash, allergy, infection, or inflammation. সহজ বাংলা: চামড়া লাল হয়ে যাওয়া।" data-rx-term="erythema" data-rx-definition="Erythema means skin redness, often from irritation, allergy, infection, or inflammation. সহজ বাংলা: চামড়া লাল হয়ে যাওয়া।">erythema, pruritus, skin burns, contact dermatitis (transdermal).

Common

Serious

Drug Interactions of Hyoscine Hydrobromide

Hyoscine Hydrobromide may interact with the following drugs

Pregnancy & Lactation Of Hyoscine Hydrobromide

 FDA Pregnancy Category C

Pregnancy

The safety of Hyoscine Hydrobromide in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. As with other drugs, it is not advisable to administer Hyoscine Hydrobromide in pregnancy.

Lactation

There are no data on the excretion of Hyoscine Hydrobromide in human breast milk. Taking Hyoscine Hydrobromide whilst breastfeeding is not recommended.

What if I take too much?

Taking 1 extra dose of hyoscine hydrobromide by accident is unlikely to harm you. But you may get more side effects, such as a dry mouth or blurred vision. The amount of hyoscine hydrobromide that can lead to an overdose varies from person to person, and too much hyoscine can be dangerous.

References

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Safety note: This is not a prescription or diagnosis. For severe symptoms, pregnancy danger signs, children with serious illness, chest pain, breathing difficulty, stroke-like weakness, or major injury, seek urgent care.

Which doctor may help?

Start with a registered doctor or the nearest qualified health center.

What to tell the doctor

  • Write when the problem started and how it changed.
  • Bring old prescriptions, investigation reports, and current medicines.
  • Write allergies, pregnancy status, diabetes, kidney/liver disease, and major past illnesses.
  • Bring one family member if the patient is weak, elderly, confused, or a child.

Questions to ask

  • What is the most likely cause of my symptoms?
  • Which danger signs mean I should go to hospital quickly?
  • Which tests are necessary now, and which can wait?
  • How should I take medicines safely and what side effects should I watch for?
  • When should I come for follow-up?

Tests to discuss

  • Vital signs: temperature, pulse, blood pressure, oxygen saturation
  • Basic physical examination by a clinician
  • CBC, urine test, blood sugar, or imaging only when clinically needed

Avoid these mistakes

  • Do not use antibiotics, steroid tablets/injections, or strong painkillers without proper medical advice.
  • Do not hide pregnancy, kidney disease, ulcer, allergy, or blood thinner use.
  • Do not delay emergency care when danger signs are present.

Medicine safety and first-aid guide

This section is for patient education only. It does not replace a doctor, pharmacist, or emergency care.

Safe first steps

  • Avoid heavy lifting, sudden bending, and prolonged bed rest.
  • Use comfortable posture and gentle movement as tolerated.
  • Discuss physiotherapy, X-ray, or MRI only when clinically needed.

OTC medicine safety

  • For mild back pain, pain-relief medicine may be discussed with a doctor or pharmacist.
  • Avoid repeated painkiller use if you have kidney disease, stomach ulcer, uncontrolled blood pressure, or are taking blood thinners.

Avoid these mistakes

  • Do not start antibiotics without a proper medical decision.
  • Do not use steroid tablets or injections casually for quick relief.
  • Do not delay emergency care because of home remedies.

Get urgent help if

  • Back pain with leg weakness, numbness around private area, loss of urine/stool control, fever, cancer history, or major injury needs urgent care.
Medicine names, dose, and timing must be decided by a qualified clinician or pharmacist after checking age, pregnancy, allergy, other diseases, and current medicines.

For rural patients and family caregivers

Patient health record and symptom diary

Write your symptoms, medicines already taken, test results, and questions before visiting a doctor. This note stays on your device unless you print or copy it.

Doctor to discuss: Emergency care / cardiology / medicine doctor
Tests to discuss with doctor
  • ECG as early as possible when chest pain suggests heart risk
  • Troponin or cardiac blood tests if doctor suspects heart attack
  • Blood pressure, oxygen level, chest examination, and other tests as advised urgently
Questions to ask
  • What is the most likely cause of my symptoms?
  • Which warning signs mean I should go to emergency care?
  • Which tests are really needed now?
  • Which medicines are safe for my age, pregnancy status, allergy, kidney/liver/stomach condition, and current medicines?
  • Is this heart-related, and do I need emergency observation?

Emergency warning signs such as chest pain, severe breathing difficulty, sudden weakness, confusion, severe dehydration, major injury, or loss of bladder/bowel control need urgent medical care. Do not wait for online information.

Safe pathway to proper treatment

Care roadmap for: Hyoscine Hydrobromide – Uses, Dosage, Side, Effects, Interaction

Use this simple roadmap to understand the next safe steps. It is educational and does not replace examination by a doctor.

Go to emergency care if you notice:
  • Severe or rapidly worsening symptoms
  • Breathing difficulty, chest pain, fainting, confusion, severe weakness, major injury, or severe dehydration
Doctor / service to discuss: Qualified healthcare provider; specialist depends on symptoms and examination.
  1. Step 1

    Check danger signs first

    If danger signs are present, seek emergency care and do not wait for online information.

  2. Step 2

    Record the symptom story

    Write when symptoms started, severity, medicines already taken, allergies, pregnancy status, and test results.

  3. Step 3

    Visit a qualified clinician

    A doctor, nurse, or qualified healthcare provider can examine you and decide which tests or treatment are needed.

  4. Step 4

    Do only useful tests

    Do tests after clinical assessment. Avoid unnecessary tests, random antibiotics, or repeated medicines without diagnosis.

  5. Step 5

    Follow up and return early if worse

    If symptoms worsen, new warning signs appear, or treatment is not helping, return for review quickly.

Rural patient practical tips
  • Take a written symptom diary and all previous prescriptions/test reports.
  • Do not hide medicines already taken, even herbal or over-the-counter medicines.
  • Ask which warning signs mean urgent referral to hospital.

This roadmap is for education. A real diagnosis and treatment plan requires history, examination, and clinical judgment.

RX Patient Help

Ask a health question safely

Write your symptom story. A health professional or site editor can review it before any answer is prepared. This box is not for emergency care.

Emergency first: Severe chest pain, breathing trouble, unconsciousness, stroke signs, severe injury, heavy bleeding, or rapidly worsening symptoms need urgent local medical care now.

Frequently Asked Questions

Mechanism Of Actions Scopolamine Hydrobromide is the hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting. Indications of Hyoscine Hydrobromide Motion sickness, Vertigo Nausea- vomiting,  Travel sickness or motion sickness Vertigo, dizziness, Drowsiness Gastrointestinal tract spasm, Genitourinary spasm IBS (irritable bowel syndrome) Postoperative nausea and vomiting Adjuvants, Anesthesia - Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease the required dosage. Cholinergic Antagonists - Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists. Muscarinic antagonists - Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. Mydriatics agents - that dilate the pupil. They may be either sympathomimetics or parasympatholytics. Since little of the medication crosses the blood-brain barrier, this drug has less effect on the brain and therefore causes a reduced occurrence of the centrally-mediated effects (such as delusions, somnolence, and inhibition of motor functions) which reduce the usefulness of some other anticholinergic drugs. Hyoscine butyl bromide - is still capable of affecting the chemoreceptor trigger zone, due to the lack of a well-developed blood-brain-barrier in the medulla oblongata, which increases the antiemetic effect it produces via local action on the smooth muscle of the gastrointestinal tract.[rx] Contraindications of Myasthenia gravis, narrow-angle glaucoma, tachycardia, megacolon; hypersensitivity Hypersensitivity to this drug Allergy Depression Porphyria Dosage of Hyoscine Hydrobromide Strength: 150mg, 300mg Dosage by tablet strength Dosage for hyoscine hydrobromide tablets (150 or 300 micrograms) Age Which strength? Dose 4 to 9 years 150 micrograms half tablet to 1 tablet 10 to 17 years 150 micrograms 1 tablet to 2 tablets 10 to 17 years 300 micrograms half tablet to 1 tablet 18 years and over 300 micrograms 1 tablet How to take tablets for excess saliva These tablets are available on prescription only. They can be taken by adults and children aged 12 years or older. The usual dose is 1 tablet (300 micrograms), 3 times a day. How to use patches for excess saliva Adults and children aged 10 years or older: Stick a patch to the skin behind the ear. Leave the patch on for 72 hours (3 days). After 72 hours, remove the patch. Stick a new patch behind the other ear. After 72 hours, remove the patch. Repeat the process. Occasionally a doctor may prescribe patches for a child under the age of 9 years. In this case, they'll use your child's weight to work out what size patch to use. They may only need to use half a patch. How to use patches for travel sickness Patches are suitable for adults and children aged 10 years or older. Stick a patch to the skin behind the ear 5 to 6 hours before the start of your journey (or the evening before you travel). Remove the patch at the end of your journey. For long journeys, you can keep the patch on for up to 72 hours (3 days). If you're still traveling after 72 hours, remove the first patch and stick a new patch behind the other ear. You can keep this on for another 72 hours if needed. Oral Gastrointestinal tract spasm, Genitourinary spasm Adult: As hyoscine butyl bromide: 20 mg 4 times daily. Child: As hyoscine butyl bromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose. Oral Prophylaxis of motion sickness Adult: As hyoscine hydrobromide: Initially, 0.15-0.3 mg 20-30 minutes before a journey, repeat 6 hourly if needed, up to max 3 doses in 24 hours. Max: 0.9 mg daily. Child: As hyoscine hydrobromide: 3-4 years Initially, 0.075 mg, repeated once if needed. Max: 0.15 mg daily; >4-10 years 0.075-0.15 mg, repeat 6 hourly if needed. Max: 0.45 mg daily; >10 years 0.15-0.30 mg, repeat 6 hourly if needed. Max: 0.9 mg daily. All doses should be given 20-30 minutes before a journey. Oral IBS (irritable bowel syndrome) Adult: As hyoscine butyl bromide: Initially, 10 mg tid, may increase up to 20 mg 4 times daily if needed. Child: As hyoscine butyl bromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose. Parenteral Motion sickness, Nausea, and vomiting, Vertigo Adult: As hyoscine hydrobromide: 0.2 mg as a single dose via IM or SC inj (may also be given via IV inj if required). Child: As hyoscine hydrobromide: 0.006 mg/kg as a single dose via IM or SC inj. Parenteral Gastrointestinal tract spasm, Genitourinary spasm Adult: As hyoscine butyl bromide: 20 mg via slow IV or IM inj, may be repeated after 30 minutes if needed. Max: 100 mg daily. Parenteral Preoperative medication Adult: As hyoscine hydrobromide: 0.2-0.6 mg given via IV, IM, or SC inj, 30-60 minutes prior to induction of anesthesia. Child: As hyoscine hydrobromide: 0.015 mg/kg given via IM or SC inj, 30-60 minutes prior to induction of anesthesia. Transdermal Prophylaxis of motion sickness Adult: As hyoscine hydrobromide patch containing 1.5 mg: Apply 1 patch behind the ear, 4-6 hours before a journey or in the evening before the journey. Child: >10 years Same as adult dose. Transdermal Postoperative nausea and vomiting Adult: As hyoscine hydrobromide patch containing 1.5 mg: Apply 1 patch behind the ear on the evening before the surgery or 1 hour before cesarean section. Discard 24 hours after the surgery. Child: >10 years Same as adult dose. Side Effects Of Hyoscine Hydrobromide The most common Symptoms of exposure to this chemical include drowsiness, sleepiness, excitement, hallucinations, delirium, psychotic behavior and central nervous system depression. Other symptoms include narcosis, mydriasis, dryness of the mouth and restlessness. Drowsiness Dry mouth Headache Indigestion Depression Skin rashes Restlessness Weight gain Mydriasis, cycloplegia, eye pruritus. Muscle weakness. Urinary retention, dysuria. Flushing, sweating, dry skin, rash, erythema, pruritus, skin burns, contact dermatitis (transdermal). Common Tachyarrhythmias, hypotension, increased intraocular pressure, drowsiness, confusional states, visual hallucinations, blurred vision, eye pain, idiosyncratic reactions (e.g. agitation, delusion, acute toxic psychosis), epileptic seizures. Dizziness, headache, equilibrium disturbance, excitement, ataxia, hallucinations, behavioural abnormalities, acute toxic psychosis, agitation, confusion, paranoia, rambling speech, fatigue, migraine, irritability, amnesia, restlessness, sedation. Bradycardia, Hypersalivation, diarrhea, dry mouth, abdominal cramps, constipation, oesophageal ulceration. Hyperpyrexia. Cough producing mucus difficulty with breathing tightness in the chest Abdominal or stomach pain and tenderness blistering, peeling, or loosening of the skin Anxiety dry mouth irritability sleepiness or unusual drowsiness trouble sleeping Decreased appetite Serious Swelling of the hands, arms, feet, ankles, or lower legs Chest pain Difficulty breathing Itching or rash Dizziness Lack of energy Black, tarry, or bloody stools Bloody vomit, or vomit that looks like coffee grounds Pale skin passing out or fainting seizures Drug Interactions of Hyoscine Hydrobromide Hyoscine Hydrobromide may interact with the following drugs Amitriptyline Tramadol Chlorpromazine Diazepam Medicines for depression (e.g. tricyclic antidepressants such as amitriptyline) Pregnancy & Lactation Of Hyoscine Hydrobromide  FDA Pregnancy Category C Pregnancy The safety of Hyoscine Hydrobromide in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. As with other drugs, it is not advisable to administer Hyoscine Hydrobromide in pregnancy. Lactation There are no data on the excretion of Hyoscine Hydrobromide in human breast milk. Taking Hyoscine Hydrobromide whilst breastfeeding is not recommended. What if I take too much?

Taking 1 extra dose of hyoscine hydrobromide by accident is unlikely to harm you. But you may get more side effects, such as a dry mouth or blurred vision. The amount of hyoscine hydrobromide that can lead to an overdose varies from person to person, and too much hyoscine can be dangerous. References https://pubchem.ncbi.nlm.nih.gov/compound/Hyoscine-hydrobromide https://www.nlm.nih.gov/copyright.html https://chem.nlm.nih.gov/chemidplus/sid/0000114498 https://chem.nlm.nih.gov/chemidplus/ https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources https://www.epa.gov/chemicals-under-tsca https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources https://en.wikipedia.org/wiki/Hyoscine_butylbromide https://pubchem.ncbi.nlm.nih.gov/compound/6603108 https://comptox.epa.gov/dashboard/DTXSID0032029 https://www.mims.com/malaysia/drug/info/hyoscine https://comptox.epa.gov/dashboard/chemical_lists/ https://echa.europa.eu/web/guest/legal-notice https://echa.europa.eu/substance-information/-/substanceinfo/100.003.682 https://echa.europa.eu/substance-information/-/substanceinfo/100.010.539 https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/20293 http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:61271 http://www.ebi.ac.uk/chebi/userManualForward.do#ChEBI%20Ontology https://www.cancer.gov/policies/copyright-reuse https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C29446 https://pubchem.ncbi.nlm.nih.gov/bioassay/1996#section=Data-Table https://ccsbase.net/ https://clinicaltrials.gov/ct2/about-site/terms-conditions#Use https://clinicaltrials.gov/ https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources https://comptox.epa.gov/dashboard/DTXSID0032029#exposure https://www.epa.gov/chemical-research/chemical-and-products-database-cpdathttps://www.clinicaltrialsregister.eu/…

References

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