Cervical Dysplastic (Congenital) Spondylolisthesis

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Cervical dysplastic (congenital) spondylolisthesis (CDS) is a rare condition in which a cervical vertebra slips forward due to developmental malformation of the posterior elements (pars interarticularis and facets) rather than trauma or degeneration. Unlike more common lumbar forms, CDS most often involves C6, with bilateral...

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Article Summary

Cervical dysplastic (congenital) spondylolisthesis (CDS) is a rare condition in which a cervical vertebra slips forward due to developmental malformation of the posterior elements (pars interarticularis and facets) rather than trauma or degeneration. Unlike more common lumbar forms, CDS most often involves C6, with bilateral pars defects and associated spina bifida on imaging E-Neurospine. Early recognition is key to avoid misdiagnosis as an acute fracture...

Key Takeaways

  • This article explains Anatomy in simple medical language.
  • This article explains Types in simple medical language.
  • This article explains Causes in simple medical language.
  • This article explains  Symptoms in simple medical language.
Educational health guideWritten for patient understanding and clinical awareness.
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Emergency safety firstUrgent warning signs are highlighted below.

Seek urgent medical care if you notice

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  • New or worsening weakness, numbness, or loss of coordination.
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  • Back or neck pain with fever, recent major injury, cancer history, or unexplained weight loss.
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See a doctor

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Definition

Cervical dysplastic (congenital) spondylolisthesis (CDS) is a rare condition in which a cervical vertebra slips forward due to developmental malformation of the posterior elements (pars interarticularis and facets) rather than trauma or degeneration. Unlike more common lumbar forms, CDS most often involves C6, with bilateral pars defects and associated spina bifida on imaging E-Neurospine. Early recognition is key to avoid misdiagnosis as an acute fracture or tumour and to guide appropriate conservative versus surgical management E-Neurospine.


Anatomy

Structure & Location
CDS affects the pars interarticularis of a cervical vertebra—most frequently C6—where a cleft allows anterior slip of that vertebra over the one below E-Neurospine.

Origin & “Insertion”
Although bony, the pars forms part of the vertebral arch connecting the superior and inferior articular processes; its “origin” and “insertion” terminology refers to its junctions with these adjacent articular facets Radiopaedia.

Blood Supply
Segmental branches of the vertebral and ascending cervical arteries supply the posterior arch, including the pars interarticularis Radiopaedia.

Nerve Supply
Sensory innervation arises from the medial branches of the dorsal rami at the affected level, making pars defects potentially painful Radiopaedia.

Functions of the Cervical Vertebrae

  1. Support: Bear the weight of the head.

  2. Protection: Encase and safeguard the cervical spinal cord.

  3. Motion: Permit flexion, extension, lateral bending, and rotation.

  4. Load Transmission: Distribute forces between head and trunk.

  5. Muscle Attachment: Serve as anchors for cervical musculature.

  6. Stability: Maintain alignment and prevent excessive slip Cleveland Clinic.


Types

According to the Wiltse–Newman system, spondylolisthesis is divided into:

  • Type I (Dysplastic/Congenital): Caused by hypoplastic facets or malformed pars; posterior elements are intact Radiopaedia.

  • Type II (Isthmic): Pars fatigue fracture, elongation, or acute break.

  • Type III (Degenerative): Facet joint pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।" data-rx-term="arthritis" data-rx-definition="Arthritis means joint inflammation causing pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।">arthritis with slip.

  • Type IV (Traumatic): Fracture of posterior elements.

  • Type V (Pathologic): Due to bone disease (tumor, infection).

  • Type VI (Iatrogenic): Post-surgical slippage Orthobullets.


Causes

  1. Developmental Pars Dysplasia (congenital malformation of chondrification centers) E-Neurospine

  2. Spina Bifida Occulta of the affected vertebra E-Neurospine

  3. Repetitive Microtrauma (e.g., sports) Orthobullets

  4. Acute Pars Fracture (trauma) Orthobullets

  5. Degenerative Facet Arthropathy PubMed Central

  6. Intervertebral Disc Degeneration PubMed Central

  7. pain and stiffness. সহজ বাংলা: বয়স/ক্ষয়ের কারণে জয়েন্টের ব্যথা।" data-rx-term="osteoarthritis" data-rx-definition="Osteoarthritis is wear-and-tear joint disease causing pain and stiffness. সহজ বাংলা: বয়স/ক্ষয়ের কারণে জয়েন্টের ব্যথা।">Osteoarthritis of cervical facets Cleveland Clinic

  8. fracture risk. সহজ বাংলা: হাড় দুর্বল হয়ে ভাঙার ঝুঁকি বেশি।" data-rx-term="osteoporosis" data-rx-definition="Osteoporosis means weak, fragile bones with higher fracture risk. সহজ বাংলা: হাড় দুর্বল হয়ে ভাঙার ঝুঁকি বেশি।">Osteoporosis weakening bony structures NCBI

  9. Hyperparathyroidism (bone resorption) NCBI

  10. Paget’s Disease of bone NCBI

  11. Metastatic Bone Disease NCBI

  12. Infectious Osteomyelitis NCBI

  13. Ankylosing Spondylitis (ankylosis stress on adjacent) NCBI

  14. Diffuse Idiopathic Skeletal Hyperostosis NCBI

  15. autoimmune joint disease causing inflammation, pain, and swelling. সহজ বাংলা: রোগপ্রতিরোধ ব্যবস্থার ভুল আক্রমণে জয়েন্টের প্রদাহ।" data-rx-term="rheumatoid arthritis" data-rx-definition="Rheumatoid arthritis is an autoimmune joint disease causing inflammation, pain, and swelling. সহজ বাংলা: রোগপ্রতিরোধ ব্যবস্থার ভুল আক্রমণে জয়েন্টের প্রদাহ।">Rheumatoid Arthritis of cervical facets NCBI

  16. Trauma-Related Nonunion (pseudoarthrosis) E-Neurospine

  17. Genetic Predisposition (familial reports) E-Neurospine

  18. Normal Variant Elongation of pedicle E-Neurospine

  19. Iatrogenic after Laminectomy Orthobullets

  20. Aggressive Physical Therapy causing microfracture Orthobullets


 Symptoms

  1. Intermittent posterior neck pain E-Neurospine

  2. Stiffness in neck movement Cleveland Clinic

  3. Occipital headaches Cleveland Clinic

  4. Cervical muscle spasm Cleveland Clinic

  5. Radicular arm pain PubMed Central

  6. Paresthesia in hands/fingers PubMed Central

  7. Weakness of upper limbs PubMed Central

  8. Hyperreflexia of biceps/triceps PubMed Central

  9. L’Hermitte’s sign (electric shocks on flexion) PubMed Central

  10. Gait disturbance (myelopathy) PubMed Central

  11. Balance issues PubMed Central

  12. Clumsiness of hands PubMed Central

  13. Spasticity in lower extremities in severe cases PubMed Central

  14. Bowel/bladder dysfunction (rare) PubMed Central

  15. Facial numbness (C2 involvement) E-Neurospine

  16. Torticollis (compensatory posture) Wascher Cervical Spine Institute

  17. Dysphagia (rare anterior slip) Wascher Cervical Spine Institute

  18. Tinel-like tapping over affected pars E-Neurospine

  19. Audible crepitus on movement Cleveland Clinic

  20. Muscle fatigue after prolonged holding Cleveland Clinic


Diagnostic Tests: Modalities

  1. Plain X-ray (Lateral, AP) – shows slip and pars defect E-Neurospine

  2. Oblique X-ray (Scotty-dog sign) Orthobullets

  3. Flexion–Extension Films – assess instability E-Neurospine

  4. Computed Tomography (CT) – cortical margins, pedicle hypoplasia E-Neurospine

  5. 3D CT Reconstruction – detailed osseous anatomy E-Neurospine

  6. Magnetic Resonance Imaging (MRI) – cord compression, soft-tissue E-Neurospine

  7. MR Myelography – CSF flow and compression E-Neurospine

  8. Single-Photon Emission CT (SPECT) – active spondylolysis Orthobullets

  9. Bone Scan – stress reaction detection Orthobullets

  10. Electromyography (EMG) – root irritation NCBI

  11. Nerve Conduction Studies – peripheral involvement NCBI

  12. Somatosensory Evoked Potentials – cord function NCBI

  13. Digital Subtraction Myelography NCBI

  14. Discography – discogenic pain differentiation NCBI

  15. Ultrasound – muscle spasm evaluation Cleveland Clinic

  16. CT Angiography – vertebral artery mapping Cleveland Clinic

  17. Dynamic MRI Cleveland Clinic

  18. Radiographic Stress Views – end-range slip E-Neurospine

  19. Videofluoroscopy – real-time motion analysis Cleveland Clinic

  20. Genetic Testing – rare syndromic cases E-Neurospine


Non-Pharmacological Treatments:  Strategies

  1. Cervical Collar (Soft/Hard) – limit motion E-Neurospine

  2. Activity Modification – avoid hyperextension Orthobullets

  3. Heat Therapy – muscle relaxation Cleveland Clinic

  4. Ice Packs – pain reduction Cleveland Clinic

  5. Traction – vertebral decompression Cleveland Clinic

  6. Manual Therapy – joint mobilization Cleveland Clinic

  7. Massage – myofascial release Cleveland Clinic

  8. Chiropractic Adjustment – realignment Cleveland Clinic

  9. Acupuncture – pain modulation Cleveland Clinic

  10. TENS – neuromodulation Cleveland Clinic

  11. Ultrasound Therapy – deep heat Cleveland Clinic

  12. Electrical Stimulation – muscle activation Cleveland Clinic

  13. Hydrotherapy – buoyancy support Cleveland Clinic

  14. Yoga – gentle stretching Cleveland Clinic

  15. Pilates – core stability Cleveland Clinic

  16. Cervical Strengthening Exercises – longus colli, trapezius Cleveland Clinic

  17. Posture Training – ergonomics Cleveland Clinic

  18. Ergonomic Pillow – neutral alignment Cleveland Clinic

  19. Workstation Adjustments – monitor height Cleveland Clinic

  20. Core Stability Training – global support Cleveland Clinic

  21. Breathing Exercises – muscle relaxation Cleveland Clinic

  22. Biofeedback – posture awareness Cleveland Clinic

  23. Aquatic Therapy – low-impact motion Cleveland Clinic

  24. Cervical Stretching – scalenes, levator scapulae Cleveland Clinic

  25. Soft Tissue Release – trigger point work Cleveland Clinic

  26. Education – body mechanics Cleveland Clinic

  27. Weight Management – load reduction Cleveland Clinic

  28. Smoking Cessation – bone health Cleveland Clinic

  29. Mindfulness Meditation – pain coping Cleveland Clinic

  30. Bracing (TLSO C‐brace) – high-grade slip stabilization Orthobullets


 Pharmacological Treatments:  Drugs

Drug Class Dosage Example Timing Common Side Effects
Ibuprofen NSAID 400 mg PO q6–8 h With meals GI upset, headache
Naproxen NSAID 250–500 mg PO BID Morning/Evening Dyspepsia, dizziness
Diclofenac NSAID 50 mg PO TID With food Edema, elevated LFTs
Celecoxib COX-2 inhibitor 100–200 mg PO BID With food Cardiovascular risk, edema
Meloxicam NSAID 7.5–15 mg PO QD Morning GI upset, dizziness
Acetaminophen Analgesic 500–1000 mg PO Q6H PRN Hepatotoxicity (high dose)
Cyclobenzaprine Muscle relaxant 5–10 mg PO TID PRN Night/PRN Sedation, dry mouth
Tizanidine Muscle relaxant 2–4 mg PO Q6–8 h PRN Hypotension, sedation
Gabapentin Neuropathic agent 300–1200 mg/day Divided doses Drowsiness, edema
Pregabalin Neuropathic agent 75–150 mg PO BID Morning/Evening Weight gain, dizziness
Duloxetine SNRI 30–60 mg PO QD Morning Nausea, dry mouth
Amitriptyline TCA 10–25 mg PO QHS Bedtime Sedation, anticholinergic
Tramadol Opioid agonist 50–100 mg PO Q4–6 h PRN Constipation, dizziness
Oxycodone Opioid agonist 5–10 mg PO Q4–6 h PRN Respiratory depression
Buprenorphine Opioid partial agonist 0.3 mg buccal q12 h PRN Sedation, nausea
Prednisone Corticosteroid 5–10 mg PO QD Morning Weight gain, hyperglycemia
Methylprednisolone Corticosteroid 4 mg PO Q6 h tapered Morning Mood changes, insomnia
Cyclo-oxygenase – reduce inflammation; SNRI – serotonin-norepinephrine reuptake inhibitor; TCA – tricyclic antidepressant.

Dosing varies by patient factors; monitor for side effects. Cleveland ClinicPubMed Central


Dietary Supplements: Options

  1. Vitamin D (1000–2000 IU/day) – bone mineralization via calcium absorption NCBI

  2. Calcium (1000–1200 mg/day) – supports bone strength NCBI

  3. Magnesium (300–400 mg/day) – cofactor for bone enzymes NCBI

  4. Omega-3 Fatty Acids (1000 mg EPA/DHA) – anti-inflammatory

  5. Glucosamine (1500 mg/day) – cartilage support

  6. Chondroitin (1200 mg/day) – joint lubrication

  7. Collagen Peptides (10 g/day) – extracellular matrix precursor

  8. Turmeric (Curcumin) (500 mg BID) – COX-2 inhibition Verywell Health

  9. Boswellia Serrata (300 mg TID) – 5-LOX pathway blockade Verywell Health

  10. MSM (Methylsulfonylmethane) (1000 mg BID) – collagen synthesis support Verywell Health


Advanced Biologic & Regenerative Agents:  Drugs

Agent Functional Category Dosage Example Mechanism
Alendronate Bisphosphonate 70 mg PO weekly Inhibits osteoclast-mediated resorption
Zoledronic Acid Bisphosphonate 5 mg IV yearly Osteoclast apoptosis
Teriparatide PTH analog 20 µg SC daily Stimulates osteoblasts
Denosumab RANKL inhibitor 60 mg SC Q6 months Blocks osteoclast formation
Hyaluronic Acid Viscosupplement 2–4 mL IA injection Improves joint lubrication
Platelet-Rich Plasma Regenerative medicine 3–5 mL injection Growth factor delivery
Mesenchymal Stem Cells Stem cell therapy 1×10⁶–10⁷ cells IA Differentiation into disc/ligament cells
BMP-2 Bone morphogenetic protein 1.5 mg in graft Induces bone formation
PRP + HA Combined biologic As above Synergistic cartilage/regeneration effect
Autologous MSCs Cell-based therapy 1×10⁶ cells per level Spinal fusion enhancement

Most are investigational; consult specialist. NCBI


Surgical Options: 10 Procedures

  1. Anterior Cervical Discectomy & Fusion (ACDF) – decompress and fuse E-Neurospine

  2. Anterior Cervical Corpectomy & Fusion – remove vertebral body, fuse E-Neurospine

  3. Posterior Cervical Laminectomy & Fusion – dorsal decompression E-Neurospine

  4. Posterior Cervical Arthrodesis – facet fusion E-Neurospine

  5. Pars Repair with Screw – direct defect fixation Orthobullets

  6. Laminoplasty – expand canal, preserve motion PubMed Central

  7. Foraminotomy – nerve root decompression PubMed Central

  8. Dynamic Stabilization (Disc-Replacement) PubMed Central

  9. Posterolateral Fusion with Instrumentation PubMed Central

  10. Minimally Invasive Cervical Fusion PubMed Central


Preventive Measures: 10 Strategies

  1. Early Detection (screen incidental findings) E-Neurospine

  2. Regular Cervical Strengthening Cleveland Clinic

  3. Postural Education Cleveland Clinic

  4. Ergonomic Workstation Setup Cleveland Clinic

  5. Avoidance of Hyperextension Activities Orthobullets

  6. Use of Protective Gear (sports) Orthobullets

  7. Routine Imaging in High-Risk Athletes Orthobullets

  8. Bone Health Optimization (vitamin D/calcium) NCBI

  9. Smoking Cessation NCBI

  10. Weight Management Cleveland Clinic


When to See a Doctor


Frequently Asked Questions (15)**

  1. What exactly is congenital cervical spondylolisthesis?
    A developmental defect of the pars interarticularis causing vertebral slip E-Neurospine.

  2. How common is CDS?
    Extremely rare—≈100 cases reported, most at C6 E-Neurospine.

  3. Can it worsen over time?
    Low-grade slips often stable; dysplastic type may progress Orthobullets.

  4. Is surgery always needed?
    No—most respond to collar and NSAIDs; surgery for instability or neurologic deficit E-Neurospine.

  5. How is CDS distinguished from fracture?
    Well-corticated margins, associated dysplasia, and spina bifida E-Neurospine.

  6. Will I need lifelong bracing?
    Usually bracing for 6–12 weeks; long-term brace rarely required Orthobullets.

  7. Can I play sports?
    Modify activities; contact sports discouraged until healed Orthobullets.

  8. Are there genetic risks?
    Possible familial patterns reported E-Neurospine.

  9. Does CDS cause headaches?
    Occipital headaches can occur due to muscle spasm Cleveland Clinic.

  10. Can CDS cause myelopathy?
    Rarely—only high-grade or cord-involving slips PubMed Central.

  11. What imaging is best?
    CT for bone detail; MRI for cord/soft tissue E-Neurospine.

  12. Is physical therapy helpful?
    Yes—strengthening and traction improve symptoms Orthobullets.

  13. Any lifestyle changes reduce risk?
    Good posture, avoid hyperextension, maintain bone health NCBI.

  14. Are supplements effective?
    Vitamin D and calcium support bone; anti-inflammatory herbs may help Verywell Health.

  15. What’s the outlook?
    Excellent with proper management; most remain symptom-free long-term E-Neurospine.

Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical  history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.

The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members

Last Updated: May 06, 2025.

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A simple rural-patient checklist to help you explain symptoms clearly, ask better questions, and avoid unsafe self-treatment.

Safety note: This is not a prescription or diagnosis. For severe symptoms, pregnancy danger signs, children with serious illness, chest pain, breathing difficulty, stroke-like weakness, or major injury, seek urgent care.

Which doctor may help?

Orthopedic doctor, spine specialist, neurologist, or physiotherapist depending on severity.

What to tell the doctor

  • Mark pain area and whether pain travels to leg.
  • Write numbness, weakness, bladder/bowel problem, fever, injury, or night pain if present.
  • Bring previous X-ray/MRI and medicine list.

Questions to ask

  • Is this muscle pain, disc problem, nerve pressure, arthritis, infection, or another cause?
  • Do I need X-ray or MRI now?
  • Which activities should I avoid and which exercises are safe?
  • When can I return to work?

Tests to discuss

  • Spine and neurological examination
  • Straight leg raise or similar nerve tension tests
  • X-ray if trauma/deformity/chronic pain is suspected
  • MRI if leg weakness, sciatica, or red flags are present

Avoid these mistakes

  • Avoid heavy lifting, long bed rest, and untrained spinal manipulation.
  • Avoid NSAIDs if ulcer, kidney disease, blood thinner use, pregnancy, or allergy unless doctor says safe.

Medicine safety and first-aid guide

This section is for patient education only. It does not replace a doctor, pharmacist, or emergency care.

Safe first steps

  • Avoid heavy lifting, sudden bending, and prolonged bed rest.
  • Use comfortable posture and gentle movement as tolerated.
  • Discuss physiotherapy, X-ray, or MRI only when clinically needed.

OTC medicine safety

  • For mild back pain, pain-relief medicine may be discussed with a doctor or pharmacist.
  • Avoid repeated painkiller use if you have kidney disease, stomach ulcer, uncontrolled blood pressure, or are taking blood thinners.

Avoid these mistakes

  • Do not start antibiotics without a proper medical decision.
  • Do not use steroid tablets or injections casually for quick relief.
  • Do not delay emergency care because of home remedies.

Get urgent help if

  • Back pain with leg weakness, numbness around private area, loss of urine/stool control, fever, cancer history, or major injury needs urgent care.
Medicine names, dose, and timing must be decided by a qualified clinician or pharmacist after checking age, pregnancy, allergy, other diseases, and current medicines.

For rural patients and family caregivers

Patient health record and symptom diary

Write your symptoms, medicines already taken, test results, and questions before visiting a doctor. This note stays on your device unless you print or copy it.

Doctor to discuss: Orthopedic / spine specialist, physical medicine doctor, or qualified clinician
Tests to discuss with doctor
  • Neurological examination for leg power, sensation, reflexes, and straight leg raise
  • X-ray only if injury, deformity, long-lasting pain, or doctor suspects bone problem
  • MRI discussion if severe nerve symptoms, weakness, bladder/bowel problem, or persistent symptoms
Questions to ask
  • What is the most likely cause of my symptoms?
  • Which warning signs mean I should go to emergency care?
  • Which tests are really needed now?
  • Which medicines are safe for my age, pregnancy status, allergy, kidney/liver/stomach condition, and current medicines?
  • Is physiotherapy, posture correction, or activity modification needed?

Emergency warning signs such as chest pain, severe breathing difficulty, sudden weakness, confusion, severe dehydration, major injury, or loss of bladder/bowel control need urgent medical care. Do not wait for online information.

Safe pathway to proper treatment

Care roadmap for: Cervical Dysplastic (Congenital) Spondylolisthesis

Use this simple roadmap to understand the next safe steps. It is educational and does not replace examination by a doctor.

Go to emergency care if you notice:
  • Severe or rapidly worsening symptoms
  • Breathing difficulty, chest pain, fainting, confusion, severe weakness, major injury, or severe dehydration
Doctor / service to discuss: Qualified healthcare provider; specialist depends on symptoms and examination.
  1. Step 1

    Check danger signs first

    If danger signs are present, seek emergency care and do not wait for online information.

  2. Step 2

    Record the symptom story

    Write when symptoms started, severity, medicines already taken, allergies, pregnancy status, and test results.

  3. Step 3

    Visit a qualified clinician

    A doctor, nurse, or qualified healthcare provider can examine you and decide which tests or treatment are needed.

  4. Step 4

    Do only useful tests

    Do tests after clinical assessment. Avoid unnecessary tests, random antibiotics, or repeated medicines without diagnosis.

  5. Step 5

    Follow up and return early if worse

    If symptoms worsen, new warning signs appear, or treatment is not helping, return for review quickly.

Rural patient practical tips
  • Take a written symptom diary and all previous prescriptions/test reports.
  • Do not hide medicines already taken, even herbal or over-the-counter medicines.
  • Ask which warning signs mean urgent referral to hospital.

This roadmap is for education. A real diagnosis and treatment plan requires history, examination, and clinical judgment.

RX Patient Help

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Write your symptom story. A health professional or site editor can review it before any answer is prepared. This box is not for emergency care.

Emergency first: Severe chest pain, breathing trouble, unconsciousness, stroke signs, severe injury, heavy bleeding, or rapidly worsening symptoms need urgent local medical care now.

Frequently Asked Questions

Is this article a replacement for a doctor?

No. It is educational content only. Patients should consult a qualified clinician for diagnosis and treatment.

When should I seek urgent care?

Seek urgent care for severe symptoms, rapidly worsening condition, breathing difficulty, severe pain, neurological changes, or any emergency warning sign.

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