RX Patient Tools
Use these quick guides before reading the article, or return to them when you need help preparing questions for a doctor.
A cervical annular tear (also called an annular fissure) is a crack or split in the annulus fibrosus, the tough outer ring of a cervical intervertebral disc. When this tear is central, it occurs in the very middle of the disc’s back wall; when paracentral, it lies just to the right or left of the center, but still toward the back of the disc. These tears weaken the disc’s structure and can allow painful inflammatory chemicals to irritate nearby nerves RadiopaediaNCBI.
Anatomy of the Cervical Annulus Fibrosus
-
Structure
The annulus fibrosus is made of 15–25 concentric rings (lamellae) of type I and II collagen, with fibers in each layer oriented about 60° to vertical, alternating directions in adjacent layers. This design gives great strength to resist compression, torsion, and bending WikipediaPhysiopedia. -
Location
Cervical discs lie between vertebrae from C2–3 down to C7–T1. The annulus forms the outer rim of each disc, surrounding the gel-like nucleus pulposus Wikipedia. -
Attachments (“Origin/Insertion”)
The outermost collagen fibers (Sharpey’s fibers) anchor into the bony vertebral endplates above and below, securing the disc to each vertebral body ChiroGeek. -
Blood Supply
In adults, the annulus is almost entirely avascular. Only the outer one-third of the outer lamellae receive tiny branches from the adjacent vertebral endplate vessels; nutrients otherwise diffuse by osmosis through the cartilage endplates PhysiopediaNCBI. -
Nerve Supply
Innervation comes via the sinuvertebral (recurrent meningeal) nerves to the outer lamellae only. Inner layers lack sensation. This is why only some annular tears cause pain Physiopedia. -
Functions
-
Shock absorption: Distributes compressive loads evenly.
-
Flexibility: Permits slight movements (flexion, extension, rotation).
-
Stability: Holds vertebrae together as a fibrous joint.
-
Containment: Keeps nucleus pulposus centered.
-
Pressure regulation: Maintains disc height and hydration.
-
Load sharing: Balances forces between anterior and posterior spinal elements Wikipedia.
-
Types of Cervical Annular Tears
Annular tears are classified by orientation and location:
-
By orientation (how the fibers split) RadiopaediaNCBI:
-
Radial tears: Start at the nucleus and extend outward.
-
Concentric tears: Split between lamellae in a ring around the nucleus.
-
Transverse (peripheral) tears: Occur in the outermost fibers near their bony attachment.
-
-
By location (where around the disc) Radiopaedia:
-
Central (midline).
-
Paracentral (just off midline).
-
Posterolateral, foraminal, extraforaminal (side regions affecting nerve roots).
-
Common Causes
-
Natural aging / disc degeneration BioMed Central
-
Repetitive bending/twisting (occupational or sports) AAFP
-
Heavy lifting (improper technique) Wikipedia
-
Vibration exposures (e.g., heavy machinery) Wikipedia
-
Torsional forces (sudden rotation) Wikipedia
-
Axial compression (impact, jumping) Wikipedia
-
Acute trauma (falls, car accidents) Florida Surgery Consultants
-
Poor posture (forward head) Florida Surgery Consultants
-
Obesity (increased spinal load) Florida Surgery Consultants
-
Smoking (impaired disc nutrition) Florida Surgery Consultants
-
Genetic predisposition (collagen gene variants) ScienceDirect
-
Occupational hazards (manual labor) NJ Spine & Orthopedic
-
Sports injuries (golf swings, weightlifting) Advanced Spine Center
-
Microtrauma (small repeated stresses) MDPI
-
Disc dehydration (loss of proteoglycans) Wikipedia
-
Enzymatic breakdown (MMPs, cathepsins) BioMed Central
-
Bone spurs (osteophyte impingement) Deuk Spine
-
Prior spine surgery (altered biomechanics) Spine-health
-
Facet joint pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।" data-rx-term="arthritis" data-rx-definition="Arthritis means joint inflammation causing pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।">arthritis (adjacent stress) BioMed Central
-
Inflammatory conditions (e.g., pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।" data-rx-term="arthritis" data-rx-definition="Arthritis means joint inflammation causing pain, swelling, stiffness, or reduced movement. সহজ বাংলা: জয়েন্টের প্রদাহ।">arthritis: Rheumatoid arthritis is an autoimmune joint disease causing infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।" data-rx-term="inflammation" data-rx-definition="Inflammation is the body’s response to injury, infection, or irritation, often causing pain, swelling, heat, or redness. সহজ বাংলা: শরীরের প্রদাহ; ব্যথা, ফোলা বা লালভাব হতে পারে।">inflammation, pain, and swelling. সহজ বাংলা: রোগপ্রতিরোধ ব্যবস্থার ভুল আক্রমণে জয়েন্টের প্রদাহ।" data-rx-term="rheumatoid arthritis" data-rx-definition="Rheumatoid arthritis is an autoimmune joint disease causing inflammation, pain, and swelling. সহজ বাংলা: রোগপ্রতিরোধ ব্যবস্থার ভুল আক্রমণে জয়েন্টের প্রদাহ।">rheumatoid arthritis) ScienceDirect
Possible Symptoms
-
Neck pain localized to the tear NCBI
-
Radiating arm pain (pain, numbness, tingling, or weakness. সহজ বাংলা: নার্ভ রুট চাপা/জ্বালায় ব্যথা বা অবশভাব।" data-rx-term="radiculopathy" data-rx-definition="Radiculopathy means nerve-root irritation or compression causing pain, numbness, tingling, or weakness. সহজ বাংলা: নার্ভ রুট চাপা/জ্বালায় ব্যথা বা অবশভাব।">radiculopathy) NCBI
-
Numbness or tingling in fingers NCBI
-
Muscle weakness in arm/hand NCBI
-
Stiffness and reduced range of motion Spine-health
-
Muscle spasms in neck/shoulder Spine-health
-
Pain with coughing/sneezing Spine-health
-
Pain aggravated by bending/extension Spine-health
-
Headache at base of skull Spine-health
-
Allodynia (light touch causes pain) Advanced Spine Center
-
Hyperalgesia (increased pain sensitivity) Advanced Spine Center
-
Cold intolerance in arm Spine-health
-
Balance disturbances (if myelopathy) AAFP
-
Gait changes (spinal cord signs) AAFP
-
Loss of fine motor control in hand AAFP
-
Lhermitte’s sign (electric shock on neck flexion) AAFP
-
Spurling’s test positive (compression pain) AAFP
-
Valsalva-induced pain Spine-health
-
Night pain disturbing sleep Spine-health
-
Weight loss/fever (red flag for systemic disease) Spine-health
Diagnostic Tests
-
Plain X-rays (alignment, degeneration) Spine-health
-
Flexion/extension X-rays (instability) Spine-health
-
MRI (high-intensity zone shows tear) Radiopaedia
-
CT scan (bony details) Spine-health
-
CT myelogram (if MRI contraindicated) Spine-health
-
Discography (provocative injection) NCBI
-
EMG/Nerve conduction (radiculopathy) AAFP
-
Somatosensory evoked potentials (cord function) AAFP
-
Spurling’s test (neck extension/rotation) AAFP
-
Jackson’s compression test (lateral bending) AAFP
-
Valsalva maneuver (increased intradiscal pressure) Spine-health
-
Cervical traction test (symptom relief) NCBI
-
Ultrasound elastography (experimental) Physiopedia
-
Bone scan (rule out infection) Spine-health
-
Lab tests (CRP, ESR) Spine-health
-
Selective nerve root block (diagnostic injection) Spine-health
-
Facet joint injection (rule out facet pain) Spine-health
-
Myelography (with CT) Spine-health
-
Autonomic testing (rare) Physiopedia
-
Psychosocial assessment (chronic pain factors) ResearchGate
Non-Pharmacological Treatments
Clinical practice guidelines consistently recommend multimodal conservative care for cervical annular tears under most circumstances JOSPTDr. Hugulet:
-
Activity modification
-
Short-term rest
-
Posture training
-
Ergonomic workstation adjustments
-
Supervised exercise therapy (strengthening & stretching)
-
Manual therapy (mobilization)
-
Cervical traction
-
Transcutaneous electrical nerve stimulation (TENS)
-
Heat application
-
Cold packs
-
Ultrasound therapy
-
Laser therapy
-
Massage therapy
-
Acupuncture
-
Dry needling
-
Yoga
-
Pilates
-
Tai Chi
-
Core stabilization exercises
-
Cervical collar (short-term)
-
Kinesio taping
-
Neuro-muscular re-education
-
Balance training
-
Aquatic therapy
-
Inversion table traction
-
Ergonomic lifting training
-
Cognitive-behavioral therapy (CBT)
-
Mindfulness & relaxation techniques
-
Patient education & self-management
-
Weight loss & smoking cessation programs
Pharmacological Treatments
-
Ibuprofen (NSAID)
-
Naproxen (NSAID)
-
Diclofenac (NSAID)
-
Celecoxib (COX-2 inhibitor)
-
Acetaminophen
-
Ketorolac (short-term)
-
Indomethacin
-
Meloxicam
-
Cyclobenzaprine (muscle relaxant)
-
Tizanidine (muscle relaxant)
-
Baclofen
-
Gabapentin (neuropathic pain)
-
Pregabalin (neuropathic pain)
-
Duloxetine (SNRI)
-
Amitriptyline (TCA)
-
Prednisone (oral steroid taper)
-
Methylprednisolone (injectable)
-
Triamcinolone (epidural steroid injection)
-
Tramadol (opioid)
-
Oxycodone (opioid) StatPearlsSpine-health.
Surgical Options
Indicated when severe, refractory radiculopathy or myelopathy occurs Verywell HealthSpine-health:
-
Anterior cervical discectomy and fusion (ACDF)
-
Anterior cervical corpectomy and fusion
-
Cervical disc arthroplasty (artificial disc replacement)
-
Posterior cervical laminoplasty
-
Posterior cervical laminectomy
-
Posterior cervical foraminotomy
-
Microdiscectomy
-
Endoscopic discectomy
-
Facet joint decompression
-
Spinal fusion with instrumentation
Prevention Strategies
-
Regular exercise to strengthen neck and core spinegroupbeverlyhills.com
-
Maintain healthy weight Florida Surgery Consultants
-
Quit smoking Florida Surgery Consultants
-
Ergonomic workstation Spine-health
-
Proper lifting techniques spinegroupbeverlyhills.com
-
Posture awareness Florida Surgery Consultants
-
Frequent movement breaks
-
Use supportive pillow/mattress
-
Hydration & nutrition
-
Spine-safe sports techniques
When to See a Doctor
-
Pain lasting > 6 weeks despite conservative care Spine-health
-
Progressive arm weakness or numbness AAFP
-
Signs of spinal cord compression (balance/gait issues) AAFP
-
Bowel or bladder dysfunction (medical emergency) Spine-health
-
Severe unrelenting night pain Spine-health
-
Fever, chills, or unexplained weight loss (infection/cancer) Spine-health
-
History of cancer or immunosuppression Spine-health
Frequently Asked Questions
-
What is a cervical annular tear?
A split in the annulus fibrosus of a neck disc that can irritate nerves NCBI. -
How does a central tear differ from a paracentral tear?
Central tears lie midline; paracentral are just off center on either side Radiopaedia. -
Are annular tears always painful?
No—only tears reaching the nerve-rich outer third usually cause pain NCBI. -
Can annular tears heal on their own?
Yes, small tears may heal over months with conservative care StatPearls. -
How long is recovery?
Most improve in 6–12 weeks; chronic tears may take up to 18 months Dr. Tony Mork. -
Is an annular tear the same as a herniated disc?
A tear is a crack; a herniation is when nucleus pulposus leaks out . -
What shows an annular tear on MRI?
A “high-intensity zone” on T2-weighted images Radiopaedia. -
Do tears cause radiculopathy?
Yes, if they irritate or compress nerve roots NCBI. -
Which exercises help?
Gentle neck stretches, chin tucks, and core stabilization Spine-health. -
When is surgery needed?
Severe, progressive neurological deficits or intractable pain despite 6 weeks of care Verywell Health. -
Can I prevent annular tears?
Yes—by maintaining good posture, healthy weight, and safe lifting Florida Surgery Consultants. -
Are injections effective?
Epidural and selective nerve root steroid injections often reduce inflammation and pain StatPearls. -
Will fusion limit my neck motion?
Fusion reduces motion at that level but may preserve overall stability Spine-health. -
What’s artificial disc replacement?
A motion-preserving surgery replacing the damaged disc with an implant AANS. -
Is chiropractic care safe?
Spinal manipulation can help in mild cases but must be done by a qualified practitioner Spine-health.
Disclaimer: Each person’s journey is unique, treatment plan, life style, food habit, hormonal condition, immune system, chronic disease condition, geological location, weather and previous medical history is also unique. So always seek the best advice from a qualified medical professional or health care provider before trying any treatments to ensure to find out the best plan for you. This guide is for general information and educational purposes only. Regular check-ups and awareness can help to manage and prevent complications associated with these diseases conditions. If you or someone are suffering from this disease condition bookmark this website or share with someone who might find it useful! Boost your knowledge and stay ahead in your health journey. We always try to ensure that the content is regularly updated to reflect the latest medical research and treatment options. Thank you for giving your valuable time to read the article.
The article is written by Team Rxharun and reviewed by the Rx Editorial Board Members
Last Updated: May 03, 2025.
- Spine-nomenclatures-spinal-cord
- Neurospine and spinal cord injury[rxharun.com]
- Lumbar Disc Herniation and Central Lumbar Spinal Stenosis[rxharun.com]
- spinal_anatomy[rxharun.com]
- lumbar-spine-anatomy[rxharun.com]
- low back pain_pathophysiology_and_mx
- daniels-et-al-2018-the-lateral-c1-c2-puncture-indications-technique-and-potential-complications
- Thoracic_Spine_Anatomy[rxharun.com]
- lumbarstenosis[rxharun.com]
- surface anatomy[rxharun.com]
- thorax-spine-objectives3[rxharun.com]
- Anatomy of spinal blood supply[rxharun.com]
- cervicalradiculopathy
- backgrounder-Spinal-Function-and-Anatomy-Fact-Sheet[rxharun.com]
- amandersson,+17453679309160118[rxharun.com]
- VERTEBRAL-CANAL-II[rxharun.com] ,
- anatomy_of_the_spinal_cord[rxharun.com]
- Vertebrae-General Anatomy[rxharun.com]
- Human Anatomy & Physiology[rxharun.com]
- Bone_Vertebrae[rxharun.com]
- anatomyofvertebralcolumn-170714070023[rxharun.com]
- Applied anatomy of the lumbar spine [rxharun.com]
- spine THE VERTEBRAL COLUMN[rxharun.com]
- Applied anatomy of the cervical spine[rxharun.com]
- spine-5-fh-thoracic-spine-anatomy[rxharun.com]
- L-Spine_spine_lumbar_anatomy [rxharun.com]
- Spine_Program_TMH-Insert-Spinal-Anatomy[rxharun.com]
- my-spine-explained[rxharun.com]
- Anatomy of the spine [rxharun.com]
- algorithm[rxharun.com]
- anatomy-and-physiology-of-lumbar-spine-tn6srjc8uq[rxharun.com]
- Boose-Degenerative-spondylolisthesis[rxharun.com]
- mri-lumbar-spine[rxharun.com][rxharun.com]
- Low_Back_Pain_Guidelines___April_2012___JOSPT[rxharun.com]
- l-spine-lumbar-spinal-stenosis[rxharun.com]
- differentiating-hip-pathology-from-lumbar-spine[rxharun.com]
- THEVERTEBRALCOLUMN[rxharun.com]
- 1403 room4 thur Holtzhausen – Examination of the lumbosacral spine[rxharun.com]
- low_back_pain[rxharun.com]
- lumbar-spine-anatomy-diagram[rxharun.com]
- Lumbar-Spine-Anatomy-and-Biomechanics[rxharun.com]
- McKenzie-Lumbar[rxharun.com]
- lhmc-rehab-protocol-post-op-lumbar-spinal-fusion[rxharun.com]
- Lumbar Spine[rxharun.com]
- post-op-lumbar-fusion[rxharun.com]
- Clinical-Biomechanics-of-spine[rxharun.com]
- spine2-mb-anatomy-and-biomech-of-the-tls-spine[rxharun.com]
- Diagnosis and Treatment of[rxharun.com]
- ow-back-pain-exercises[rxharun.com]
- Thoracic_Lumbosacral_and_Pelvic_Regions_new[rxharun.com]
- spine-low-back-assess-clinical-pathways[rxharun.com]
- Lumbar Core Strength[rxharun.com]
- Stability of the lumbar spine[rxharun.com]
- lumbar-radiofrequency-ablabtion-[rxharun.com]
- Clinical examination of the lumbar spine[rxharun.com]
- anatomy-of-the-spine Typical vertebral anatomy-lateral view[rxharun.com]
- Applied anatomy of the lumbar spine[rxharun.com]
- Lumbar Spine Range of Movement Exercise Program[rxharun.com]
- Morphometric Study of Lumbar Vertebrae[rxharun.com]
- witek2019[rxharun.com] Wilcyznski_MRI-lumbar[rxharun.com]
- biomechanics-of-lumbar-spine-and-lumbar-disc[rxharun.com]
- Lumbar Spine Muscles and Movement [rxharun.com]
- L-Spine_spine_lumbar_anatomy[rxharun.com]
- Nomenclature[rxharun.com]
- spine-low-back-assess-clinical-pathways[rxharun.com]
- Cervical-and-Thoracic-Spine-Disorders-Guideline[rxharun.com]
- spine-1-jk-anatomy-of-the-spine[rxharun.com]
- Physical Exam of the Spine[rxharun.com]
- degenerative pathology of the spine new[rxharun.com]
- Spinal-pathology-Drop-foot-Thoracic-pain-Inflammatory-Back-Pain[rxharun.com]
- Many Facets of Spine Pathology[rxharun.com]
- osteoarthritis-of-the-spine-information[rxharun.com]
- MRI in Lumber Disc Degenerative Diseases[rxharun.com]
- ARTIFICIAL INTERVERTEBRAL DISCS LUMBAR SPINE[rxharun.com]
- 2022985[rxharun.com]
- amandersson[rxharun.com]
- lumbardischerniation[rxharun.com]
- Anaesthesia-for-paediatric-dentistry[rxharun.com]
- Developments in intervertebral disc disease research_ pathophysiotherapy[rxharun.com]
- 2025.03.13.643128v1.full[rxharun.com]
- Lumbar_Disc_Herniation[rxharun.com]
- Biomechanics of the Lumbar[rxharun.com]
- percutaneous annular puncture[rxharun.com]
- The nucleus pulposus microenvironment i[rxharun.com]
- Intervertebral Disc Stress [rxharun.com]
- degenerative changes of the intervertebral disc[rxharun.com]
- Dixon_AR, Mechanical Engineering, PhD, 2022[rxharun.com]
- INTERVERTEBRAL DISC DEGENERATION [rxharun.com]
- Intervertebral disc degeneration rx[rxharun.com]
- Biological Therapeutic Modalities for Intervertebral[rxharun.com]
- intervertebral-disc-mechanics-[rxharun.com]
- Intervertebral Disc Damage & Repair[rxharun.com]
- disc_prolapse_pathology_2016[rxharun.com]
- Strontium Ranelate Ameliorates Intervertebral Disc[rxharun.com]
- faysal_bas_it,+841_221-223[rxharun.com]
- LUMBAR PROLAPSED INTERVERTEBRAL[rxharun.com]
- nrrheum.2014-disc-nutrient-review[rxharun.com]
- Intervertebral Disc Degeneration[rxharun.com]
- Structure and Biology of the Intervertebral Disk in Health and Disease[rxharun.com]
- amandersson,+17453679309160104[rxharun.com]
- Ligamentum Flavum at L4-5[rxharun.com]
- Bone_Vertebrae[rxharun.com]
- Anatomy of the spine[rxharun.com]
- lab manual_spinal cord and spinal nerves_a+p[rxharun.com]
- Spinal Cord Functions & Reflexes[rxharun.com]
- Nervous System Lect Notes[rxharun.com]
- Central nervous system[rxharun.com]
- Nervous System.BD[rxharun.com]
- SAJAA(V26N6)+p40-44+09+2535+Spinal+cord+pathways[rxharun.com]
- Spinal-cord[rxharun.com]
- spinalcord[rxharun.com]
- Management of[rxharun.com]
- integrated-care-pathway-spinal-cord-injury[rxharun.com]
- Spinal Cord Spinal Nerve Anatomy[rxharun.com]
- 1st-Professional-MBBS-Chapter-wise-Questions[rxharun.com]
- Key_Sensory_Points[rxharun.com]
- Spinal-cord-slides[rxharun.com]
- Range_of_Motion[rxharun.com]
- yes-you-can_digital[rxharun.com]
- Motor_Exam_Guide[rxharun.com]
- Living-with-a-Spinal-Cord-Injury[rxharun.com]
- The Spinal Cord and Spinal Nerves[rxharun.com]
- Spinal cord nerves [rxharun.com]
- anatomy-of-the-circulation-of-the-brain-and-spinal-cord[rxharun.com]
- Spinal_cord_Tracts[rxharun.com]
- Spinal Cord Injury[rxharun.com]
- spinal cord[rxharun.com]
- SpinalCord34[rxharun.com]
- Spinal_Cord_Anatomy_and_Localization.-compressed[rxharun.com]
- Functions of the Spinal Cord[rxharun.com]
- Spinal Cord Organization[rxharun.com]
- Spinal Cord, Spinal Nerves[rxharun.com]
- AnatomyBackSpinalCord-StatPearls-NCBIBookshelf[rxharun.com]
- SpinalCord nerve, reflexes, coloumn[rxharun.com]
- Spinal Cord, nerve, reflexes[rxharun.com]
- Anatomy of the Spinal Cord [rxharun.com]
- Spinal+cord+pathways[rxharun.com]
- L2-Anatomy of Spinal cord[rxharun.com]
- fnhum-11-00343[rxharun.com]
- spine_injury_guidelines[rxharun.com]
- spine-care-for-the-therapist[rxharun.com]
- thoracic spine based on graphical images[rxharun.com]
- Spine-biomechanics[rxharun.com]
- ajnr_1_1_009[rxharun.com]
- Ultrasonography of the Adult Thoracic and Lumbar Spine for Central Neuraxial Blockade [rxharun.com]
- thoracic-spine[rxharun.com]
- JAAOS_Management_of_Thoracic_and_lumbar_metastases[rxharun.com]
- THEVERTEBRALCOLUMN[rxharun.com]
- Spine7 Treatment of Fractures of the Thoracic and Lumbar Spine[rxharun.com]
- Thoracic_spine_mobility_an_essential_link_in_upper_limb_kinetic_chains_a_systematic_review_v2[rxharun.com]
- Disorders of the thoracic spine pathology treatment[rxharun.com]
- Thoracoscopy-A-Minimally-Invasive-Approach-to-the-Anterior-Thoracic-Spine[rxharun.com]
- Thoracic-Spine-Anatomy-and-Biomechanics[rxharun.com]
- thoracic-mobility-and-athletic-performance[rxharun.com]
- Thoracic_Lumbosacral_and_Pelvic_Regions_new[rxharun.com]
- Thoracic Home Exercise Program[rxharun.com]
- Thoracic Posture and Mobility in Mechanical Neck[rxharun.com]
- Thoracic_and_Lumbar_Spine_ROM_exercise_programme_done_2019[rxharun.com]
- spine-5-fh-thoracic-spine-anatomy[rxharun.com]
- Clinical examination of the thoracic spine[rxharun.com]
- TIMS-Managing-Thoracic-Back-Pain-July-2024[rxharun.com]
- Cervical-and-Thoracic-Spine-Disorders-[rxharun.com]
- https://upload-media.rxharun.com/wp-content/uploads/2017/02/Nomenclature.pdf
- https://pubmed.ncbi.nlm.nih.gov/27887750/
- https://www.ncbi.nlm.nih.gov/books/NBK537139/
- https://www.ncbi.nlm.nih.gov/books/NBK537236/
- https://www.ncbi.nlm.nih.gov/books/NBK537140/
- https://pubmed.ncbi.nlm.nih.gov/30335291/
- https://pubmed.ncbi.nlm.nih.gov/30725921/
- https://pubmed.ncbi.nlm.nih.gov/30725824/
- https://www.ncbi.nlm.nih.gov/books/NBK559006/
- https://pubmed.ncbi.nlm.nih.gov/30725825/
- https://en.wikipedia.org/wiki/Muscle
- https://en.wikipedia.org/wiki/List_of_skeletal_muscles_of_the_human_body
- https://medlineplus.gov/ency/imagepages/19841.htm
- https://www.britannica.com/science/human-muscle-system
- https://training.seer.cancer.gov/anatomy/muscular/types.html
- https://www.britannica.com/science/human-muscle-system
- https://www.sciencedirect.com/topics/medicine-and-dentistry/skeletal-muscle
- https://academic.oup.com/nar/article/32/5/1792/2380623
- https://onlinelibrary.wiley.com/journal/10974598
- https://medlineplus.gov/skinconditions.html
- https://en.wikipedia.org/wiki/Category:Kidney_diseases
- https://kidney.org.au/your-kidneys/what-is-kidney-disease/types-of-kidney-disease
- https://www.niddk.nih.gov/health-information/kidney-disease
- https://www.kidney.org/kidney-topics/chronic-kidney-disease-ckd
- https://www.kidneyfund.org/all-about-kidneys/types-kidney-diseases
- https://www.aad.org/about/burden-of-skin-disease
- https://www.usa.gov/federal-agencies/national-institute-of-arthritis-musculoskeletal-and-skin-diseases
- https://www.cdc.gov/niosh/topics/skin/default.html
- https://www.mayoclinic.org/diseases-conditions/brain-tumor/symptoms-causes/syc-20350084
- https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Understanding-Sleep
- https://www.cdc.gov/traumaticbraininjury/index.html
- https://www.skincancer.org/
- https://illnesshacker.com/
- https://endinglines.com/
- https://www.jaad.org/
- https://www.psoriasis.org/about-psoriasis/
- https://books.google.com/books?
- https://www.niams.nih.gov/health-topics/skin-diseases
- https://cms.centerwatch.com/directories/1067-fda-approved-drugs/topic/292-skin-infections-disorders
- https://www.fda.gov/files/drugs/published/Acute-Bacterial-Skin-and-Skin-Structure-Infections—Developing-Drugs-for-Treatment.pdf
- https://dermnetnz.org/topics
- https://www.aaaai.org/conditions-treatments/allergies/skin-allergy
- https://www.sciencedirect.com/topics/medicine-and-dentistry/occupational-skin-disease
- https://aafa.org/allergies/allergy-symptoms/skin-allergies/
- https://www.nibib.nih.gov/
- https://www.nei.nih.gov/
- https://en.wikipedia.org/wiki/List_of_skin_conditions
- https://en.wikipedia.org/?title=List_of_skin_diseases&redirect=no
- https://en.wikipedia.org/wiki/Skin_condition
- https://oxfordtreatment.com/
- https://www.nidcd.nih.gov/health/
- https://consumer.ftc.gov/articles/w
- https://www.nccih.nih.gov/health
- https://catalog.ninds.nih.gov/
- https://www.aarda.org/diseaselist/
- https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets
- https://www.nibib.nih.gov/
- https://www.nia.nih.gov/health/topics
- https://www.nichd.nih.gov/
- https://www.nimh.nih.gov/health/topics
- https://www.nichd.nih.gov/
- https://www.niehs.nih.gov
- https://www.nimhd.nih.gov/
- https://www.nhlbi.nih.gov/health-topics
- https://obssr.od.nih.gov/
- https://www.nichd.nih.gov/health/topics
- https://rarediseases.info.nih.gov/diseases
- https://beta.rarediseases.info.nih.gov/diseases
- https://orwh.od.nih.gov/
