Category: Drugs (A – Z)

Avelumab is a monoclonal antibody used to treat metastatic Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma. Avelumab is a programmed death...

Avapritinib is an orally bioavailable inhibitor of specific mutated forms of platelet-derived growth factor receptor alpha (PDGFR alpha; PDGFRa) and mast/stem cell factor receptor...

Atezolizumab is a humanized IgG1 monoclonal anti-programmed death-ligand 1 (PD-L1) antibody is a monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with...

ASPARLAS (calaspargase pegol-mknl) is indicated as a component of a multiagent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) in pediatric and...

Calaspargase pegol is an asparagine-specific enzyme used to treat acute lymphoblastic leukemia. Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL)...

Anastrozole is a nonsteroidal inhibitor of aromatase that effectively blocks estrogen synthesis in postmenopausal women and is used as therapy for estrogen receptor-positive breast...

Asparaginase Erwinia chrysanthemi is an asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma. Asparaginase Erwinia...

Asciminib is an orally bioavailable, allosteric Bcr-Abl1 tyrosine kinase inhibitor, with antineoplastic activity. Upon administration, asciminib targets and binds to the myristoyl pocket of the Bcr-Abl1...

Ofatumumab is an anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer...

Arsenic trioxide is a chemotherapeutic agent of the idiopathic function used to treat leukemia that is unresponsive to first-line agents. It is suspected that...

Nelarabine is a purine analog and antineoplastic agent used in the therapy of T-cell lymphoblastic leukemia or lymphoma. Nelarabine is associated with a low rate...

Exemestane is a steroidal inhibitor of aromatase that effectively blocks estrogen synthesis in postmenopausal women and is used as therapy for estrogen receptor-positive breast...

Darbepoetin alfa is a recombinant form of human erythropoietin used to increase the differentiation of progenitor cells to red blood cells in the treatment...

Aprepitant is an orally available antiemetic agent that is used to prevent postoperatively or cancer chemotherapy-related nausea and vomiting. Aprepitant is associated with a...

Apalutamide is a nonsteroidal antiandrogen used to treat nonmetastatic castration-resistant prostate cancer. Apalutamide is associated with a low rate of serum enzyme elevation during...

Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with...

Amifostine Anhydrous is a phosphorylated aminosulfhydryl compound with cytoprotective activity. Amifostine is dephosphorylated by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite in...

Aminolevulinic Acid is a topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer....