Cutis laxa with bone dystrophy is a rare connective-tissue disorder in which the skin is loose, saggy, and less elastic because elastic fibers and related ...

Spondylocostal dysostosis (SCDO) is a rare birth condition where the bones of the spine (vertebrae) and ribs do not form and separate normally before birth. ...

Osteosclerosis fragilis is an old, Latinized name that physicians used for a condition in which bones look very dense (sclerotic) but are paradoxically ...

Spondylolysis means there is a small break (a “stress fracture”) or a thinning/defect in a narrow bridge of bone at the back of a vertebra called the pars ...

Aneurysm-osteoarthritis syndrome is a rare, inherited connective-tissue disorder. It mainly causes bulging (aneurysms), stretching (tortuosity), or tearing ...

Spinal and bulbar muscular atrophy (SBMA) is a rare, slowly progressive nerve-and-muscle disease that mainly affects adult males. It happens because of a ...

Dysostosis is a group of birth conditions that affect how certain bones form and join. The problem starts very early in pregnancy when the baby’s skeleton is ...

Autosomal dominant late-onset spinal muscular atrophy (AD-LO-SMA) is a group of rare genetic disorders in which the lower motor neurons in the spinal cord ...

Acro-renal-mandibular syndrome is a very rare condition that is present from birth. It affects three main body areas at the same time: the hands and feet ...

Sesamoiditis is an overuse injury characterized by inflammation of the two tiny sesamoid bones embedded under the big toe joint (the first metatarsophalangeal ...

Psoriatic arthritis–related dactylitis, often called “sausage digit,” is a hallmark feature of psoriatic arthritis (PsA) characterized by diffuse swelling of ...

Infectious (Septic) Dactylitis is a specific form of dactylitis in which an invading pathogen—most often bacteria—infects the bone (osteomyelitis) and ...

Reactive dactylitis, often called “sausage digit,” refers to a diffuse swelling of an entire finger or toe that arises as part of reactive arthritis. In ...

Tenosynovitis-predominant dactylitis is a form of sausage digit in which inflammation of the tendon sheaths (tenosynovium) drives the characteristic swelling ...

Psoriatic dactylitis, often called “sausage digit,” is the swelling of an entire finger or toe due to inflammation of joints, tendon sheaths, and soft tissues. ...

Sickle cell dactylitis, often called “hand–foot syndrome,” is one of the earliest painful complications of sickle cell disease. It happens when sickled red ...

Dactylitis—often called “sausage digit”—is a medical term describing uniform swelling of an entire finger or toe. This swelling gives the digit a sausage-like ...

Costochondral enthesitis is an inflammatory condition that affects the point where the ribs meet the costal cartilage of the chest wall. This junction—known as ...

Medial epicondyle enthesitis is a condition in which the spot where the forearm flexor and pronator tendons attach to the inner (medial) bony bump of the elbow ...

Enthesitis refers to inflammation at the enthesis, the specific site where a tendon or ligament attaches to bone. In this condition, the normal collagen fibers ...