Drugs (A – Z) – RxHarun

Vasodilator drugs relax and widen blood vessels, increasing blood flow. A few examples include ACE inhibitors, ARBs, calcium channel blockers, and nitrates. Vasodilators are medicines ...

Drugs (A - Z)

Methamphetamine Hydrochloride – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Methamphetamine Hydrochloride is the hydrochloride salt form of methamphetamine, an amphetamine and sympathomimetic amine with CNS stimulating properties. Methamphetamine hydrochloride acts by ...

Drugs (A - Z)

Methamphetamine – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Methamphetamine is a member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. It has a role as a neurotoxin, a psychotropic drug, a central ...

Drugs (A - Z)

Vitamin D3 – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Cholecalciferol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form ...

Drugs (A - Z)

Imidazole – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of ...

Drugs (A - Z)

Carbimazole

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Carbimazole is a member of the class of imidazoles that is methimazole in which the nitrogen-bearing hydrogen is converted into its methoxycarbonyl derivative. A prodrug for methimazole, ...

Drugs (A - Z)

Methylthiouracil – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism. Methylthiouracil is an organosulfur compound that is used in antithyroid ...

Drugs (A - Z)

Propylthiouracil – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Propylthiouracil is a Thyroid Hormone Synthesis Inhibitor. The mechanism of action of propylthiouracil is as a Thyroid Hormone Synthesis Inhibitor.6-propyl-2-thiouracil is ...

Drugs (A - Z)

Methimazole

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Methimazole ( Metirox 5 and 10 mg) is a member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen that is attached to nitrogen. It has a role as ...

Drugs (A - Z)

Mirogabalin – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mirogabalin has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain.Mirogabalin is a medication ...

Drugs (A - Z)

Enprostil – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Enprostil is a synthetic prostaglandin designed to resemble dinoprostone. Enprostil was found to be a highly potent inhibitor of gastric HCl secretion. It is an analog of prostaglandin E2 but unlike ...

Drugs (A - Z)

Tafasitamab – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies. It is produced using recombinant DNA technology in Chinese hamster ovary ...

Drugs (A - Z)

Mogamulizumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mogamulizumab is a CCR4-targeted immuno-oncology drug. It is intended to deplete CCR4-expressing Treg cells in the tumor microenvironment so as to release Teff cells from Treg-mediated suppression ...

Drugs (A - Z)

Mobocertinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mobocertinib is a Kinase Inhibitor. The mechanism of action of mobocertinib is as a HER1 Antagonist and Cytochrome P450 3A Inducer. Mobocertinib is an inhibitor of EGFR that irreversibly binds to and ...

Drugs (A - Z)

Mitoxantrone – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mitoxantrone is an antineoplastic antibiotic that is used in the treatment of acute leukemia, lymphoma, and prostate and breast cancer, but also for late-stage, severe multiple sclerosis. ...

Drugs (A - Z)

Mirvetuximab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mirvetuximab Soravtansine is an immunoconjugate consisting of the humanized monoclonal antibody M9346A against folate receptor 1 (FOLR1) conjugated, via the disulfide-containing cleavable linker ...

Drugs (A - Z)

Midostaurin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Midostaurin is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3) which is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 ...

Drugs (A - Z)

Methylnaltrexone Bromide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Methylnaltrexone is a methyl derivative of noroxymorphone with selective, opioid-receptor antagonistic activity. Methylnaltrexone is a member of phenanthrenes. Methylnaltrexone displaces opioids from ...

Drugs (A - Z)

Mercaptoethanesulfonic Acid – Uses, Dosage, Side Effects

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

2-mercaptoethanesulfonic acid is a Cytoprotective Agent. Coenzyme M is an organosulfonic acid consisting of a sulfonic acid having a 2-mercaptoethanol group attached to sulfur. It has a role as ...

Drugs (A - Z)

Mesna – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

2-mercaptoethanesulfonic acid is a Cytoprotective Agent. Coenzyme M is an organosulfonic acid consisting of a sulfonic acid having a 2-mercaptoethanol group attached to sulfur. It has a role as ...

Drugs (A - Z)

Trametinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Trametinib is a dual-kinase inhibitor that is used in the treatment of advanced malignant melanoma, usually in combination with dabrafenib. Trametinib therapy is associated with transient ...

Drugs (A - Z)

Mechlorethamine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mechlorethamine is a nitrogen mustard and antineoplastic agent that has been in clinical use for more than 60 years, given systemically in combination with other antineoplastic agents to treat ...

Drugs (A - Z)

Margetuximab-cmkb – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Margetuximab is an Fc-engineered human/mouse chimeric IgG1κ anti-HER2 monoclonal antibody indicated for patients with HER2-positive metastatic breast cancer. The HER2 oncoprotein, the product of the ...

Drugs (A - Z)

Futibatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Futibatinib is an FGF receptor 2 kinase inhibitor that is used in the treatment of unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma. Futibatinib is associated with ...

Drugs (A - Z)

Olaparib – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Olaparib is a small molecule inhibitor of poly ADP-ribose polymerase and is used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. Olaparib therapy is ...

Drugs (A - Z)

Lutetium Lu 177 Dotatate – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lutetium Lu 177 Dotatate is a radio-conjugate consisting of the tyrosine-containing somatostatin analog Tyr3-octreotate (TATE) conjugated with the bifunctional, macrocyclic chelating agent ...

Drugs (A - Z)

Luspatercept-aamt – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Luspatercept is an erythroid maturation agent used to treat anemia secondary to beta-thalassemia in patients requiring regular red blood cell transfusions. Luspatercept is a recombinant fusion ...

Drugs (A - Z)

Lurbinectedin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lurbinectedin is an antineoplastic alkylating agent and synthetic derivative of trabectedin that is used to treat refractory, metastatic small-cell lung cancer. Lurbinectedin therapy is ...

Drugs (A - Z)

Moxetumomab Pasudotox – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Moxetumomab pasudotox is a CD22-specific antibody conjugated to a truncated exotoxin used to treat relapsed or refractory hairy cell leukemia in patients who have already been treated with a purine ...

Drugs (A - Z)

Sotorasib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Sotorasib is an orally available inhibitor of the specific KRAS mutation, p.G12C, with potential antineoplastic activity. Upon oral administration, sotorasib selectively targets, binds to, and ...

Drugs (A - Z)

Lorlatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lorlatinib is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK), and C-ros oncogene 1 (Ros1), with potential antineoplastic ...

Drugs (A - Z)

Tipiracil Hydrochloride – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tipiracil Hydrochlorideis the combination of an antineoplastic pyrimidine analog (trifluridine) with an inhibitor of its metabolism (tipiracil) that is used in the therapy of refractory, ...

Drugs (A - Z)

Trifluridine/Tipiracil – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Trifluridine/tipiracil is the combination of an antineoplastic pyrimidine analog (trifluridine) with an inhibitor of its metabolism (tipiracil) that is used in the therapy of refractory, ...

Drugs (A - Z)

Loncastuximab Tesirine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Loncastuximab tesirine is an antibody-drug conjugate used for the treatment of relapsed and refractory B-cell lymphomas.Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) is a ...

Drugs (A - Z)

Lomustine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lomustine is an orally administered alkylating agent used alone and in combination with other antineoplastic agents in the treatment of several malignancies including Hodgkin's disease, ...

Drugs (A - Z)

Leuprolide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Leuprolide Acetate is the acetate salt of a synthetic nonapeptide analog of the gonadotropin-releasing hormone. A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that ...

Drugs (A - Z)

Lenvatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lenvatinib is orally available multi-kinase inhibitor and antineoplastic agent that is used in treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma. ...

Drugs (A - Z)

Larotrectinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Larotrectinib is a selective inhibitor of neurotrophin receptor kinase (NTRK) that is used in the therapy of solid tumors harboring NTRK gene fusions. Larotrectinib is associated with a high ...

Drugs (A - Z)

Lanreotide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Lanreotide is a synthetic polypeptide analog of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon, and many ...

Drugs (A - Z)

Tisagenlecleucel – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 ...

Drugs (A - Z)

Adagrasib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Adagrasib is an orally available, small-molecule inhibitor that targets the oncogenic KRAS substitution mutation, G12C, with potential antineoplastic activity. Upon oral administration ...

Drugs (A - Z)

Selumetinib Sulfate – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Selumetinib is an orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent inhibitor of mitogen-activated protein kinase kinase (MEK or MAPK/ERK ...

Drugs (A - Z)

tebentafusp-tebn – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tebentafusp is a bispecific gp100 peptide-HLA-directed CD3 T cell engager used to treat unresectable or metastatic uveal melanoma. Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. It ...

Drugs (A - Z)

Pembrolizumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Pembrolizumab is a monoclonal antibody used to treat certain types of cancer. It works by blocking a certain protein in the body that helps cancer cells grow and spread. This protein is called ...

Drugs (A - Z)

Palifermin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Palifermin is a modified truncated form of human keratinocyte growth factor produced by recombinant DNA technology. Palifermin is used to treat oral sores and ulcers to prevent and treat oral ...

Drugs (A - Z)

Mitomycin – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C ...

Drugs (A - Z)

Ruxolitinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ruxolitinib is a small molecule Janus kinase inhibitor that is used in the treatment of intermediate or high-risk myelofibrosis and resistant forms of polycythemia vera and graft-vs-host ...

Drugs (A - Z)

Ixazomib Citrate – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ixazomib is an active metabolite of MLN9708, a second-generation, boron-containing peptide proteasome inhibitor (PI) or proteasome inhibitor with potential antineoplastic activity. Ixazomib ...

Drugs (A - Z)

Ivosidenib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ivosidenib is an orally available small-molecule inhibitor of isocitrate dehydrogenase 2 which is used as an antineoplastic agent in the treatment of selected cases of acute myeloid leukemia ...

Drugs (A - Z)

Romidepsin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Romidepsin is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous and peripheral T-cell lymphomas. ...

Drugs (A - Z)

Isatuximab-irfc – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Isatuximab is a chimeric monoclonal antibody targeted against surface CD38 glycoproteins for the treatment of multiple myeloma in patients who have failed previous therapies.Isatuximab (formerly ...

Drugs (A - Z)

Ipilimumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ipilimumab is a human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma. Ipilimumab is a fully humanized IgG1 monoclonal antibody that ...

Drugs (A - Z)

Cedazuridine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Cedazuridine is an orally available synthetic nucleoside analog derived from tetrahydrouridine (THU) and cytidine deaminase inhibitor (CDAi), that can potentially be used to prevent the ...

Drugs (A - Z)

Infigratinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Infigratinib is a FGF receptor kinase inhibitor that is used in the treatment of unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma. Infigratinib is associated with ...

Drugs (A - Z)

Cancer Drugs

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

There are many different types of cancer medications. These include alkylating agents, antimetabolites, and plant alkaloids. Doctors can use cancer medications either on their own or in combination ...

Drugs (A - Z)

Talimogene Laherparepvec – Uses, Dosage, Side Effects

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Talimogene laherparepvec is an oncolytic treatment used in the local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically ...

Drugs (A - Z)

Imiquimod – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Imiquimod is a prescription medicine approved by the U.S. Food and Drug Administration (FDA). It is a cream for topical use only. Imiquimod is FDA-approved for the treatment of certain skin ...

Drugs (A - Z)

Tremelimumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). CTLA-4 is a cell surface receptor ...

Drugs (A - Z)

Durvalumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Durvalumab is a human monoclonal antibody to programmed cell death ligand 1 (PD-L1), which acts as a checkpoint inhibitor and is used in the immunotherapy of several forms of advanced or metastatic ...

Drugs (A - Z)

Idelalisib – Uses, Dosage, Side Effects, Interation

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Idelalisib is an oral kinase inhibitor that is approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed ...

Drugs (A - Z)

Ponatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ponatinib is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Ponatinib inhibits unmutated and all ...

Drugs (A - Z)

Ifosfamide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ifosfamide is a parenterally administered alkylating agent similar to cyclophosphamide that is used in the treatment of several forms of cancer including lymphomas, sarcoma, and advanced forms ...

Drugs (A - Z)

Ibrutinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ibrutinib is an orally bioavailable, small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon oral administration, ibrutinib binds to and ...

Drugs (A - Z)

Ibritumomab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Ibritumomab tiuxetan is a monoclonal anti-CD20 antibody used to treat B-cell non-Hodgkin lymphoma via a conjugated radioactive isotope. Indium or yttrium conjugated murine IgG1 kappa monoclonal ...

Drugs (A - Z)

Hydroxyurea – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Hydroxyurea is a mono hydroxyl-substituted urea (hydroxy carbamate) antimetabolite. Hydroxyurea selectively inhibits ribonucleoside diphosphate reductase, an enzyme required to convert ...

Drugs (A - Z)

Topotecan – Uses, Dosage, Side Effects, Interactions

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Topotecan is a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminate. Topotecan is a Topoisomerase Inhibitor. The ...

Drugs (A - Z)

Which Drugs Are Use For Destroy the Sex?

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Which Drugs Are Use For Destroy the Sex?/Goserelin is a synthetic long-acting agonist of the GONADOTROPIN-RELEASING HORMONE and is used in treatments of malignant NEOPLASMS of the prostate, ...

Drugs (A - Z)

Goserelin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Goserelin is a synthetic long-acting agonist of the GONADOTROPIN-RELEASING HORMONE and is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast ...

Drugs (A - Z)

Glucarpidase – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Glucarpidase is the recombinant form of the Pseudomonas sp. (strain RS-16) enzyme carboxypeptidase G2 that is produced in Escherichia coli. In patients, glucarpidase inactivates methotrexate, and ...

Drugs (A - Z)

Glasdegib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Glasdegib is an orally available small molecule inhibitor of the signaling molecule hedgehog which is used as an antineoplastic agent in the treatment of acute myeloid leukemia. Glasdegib is ...

Drugs (A - Z)

Gilteritinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Gilteritinib is an orally bioavailable inhibitor of the receptor tyrosine kinases (RTKs) FMS-like tyrosine kinase 3 (FLT3; STK1; FLK2), AXL (UFO; JTK11), anaplastic lymphoma kinase (ALK; ...

Drugs (A - Z)

Afatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic ...

Drugs (A - Z)

Gemtuzumab ozogamicin – Uses, Dosage, Side Effects, Interation

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Gemtuzumab ozogamicin is a monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia. Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody that is conjugated ...

Drugs (A - Z)

Gefitinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Gefitinib is an anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR), ...

Drugs (A - Z)

Obinutuzumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Obinutuzumab is an antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil. Obinutuzumab is a humanized monoclonal antibody used as a ...

Drugs (A - Z)

Pralsetinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Pralsetinib is an orally bioavailable selective inhibitor of mutant forms of and fusion products involving the proto-oncogene receptor tyrosine kinase RET, with potential antineoplastic activity. ...

Drugs (A - Z)

Human Papillomavirus (HPV) Vaccine

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

The 9-valent human papillomavirus (HPV) vaccine (9vHPV) is a vaccine used in the management and prevention of infection with human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, 45, 52, 58. It ...

Drugs (A - Z)

Sirolimus – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Sirolimus is macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection ...

Drugs (A - Z)

Futibatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Futibatinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. Futibatinib selectively and irreversibly binds to and inhibits ...

Drugs (A - Z)

Pegfilgrastim – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Pegfilgrastim is a recombinant human granulocyte colony-stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive ...

Drugs (A - Z)

Tivozanib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tivozanib is a Kinase Inhibitor. The mechanism of action of tivozanib is as a Tyrosine Kinase Inhibitor. Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor ...

Drugs (A - Z)

Fostamatinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Fostamatinib is an orally available small-molecule inhibitor of spleen tyrosine kinase that is used to treat chronic immune thrombocytopenia. Fostamatinib is associated with transient and ...

Drugs (A - Z)

Receptors – Cellular Signalling

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell ...

Drugs (A - Z)

Enzymes A to Z

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into ...

Drugs (A - Z)

Pralatrexate – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Pralatrexate is a folate analog inhibitor of dihydrofolate reductase (DHFR) exhibiting a high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. ...

Drugs (A - Z)

Leucovorin – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Leucovorin is a derivative of folic acid with chemoprotection, antidote, and synergistic activity. Leucovorin does not require metabolism by dihydrofolate reductase, the molecular target of ...

Drugs (A - Z)

Flutamide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Flutamide is an Androgen Receptor Inhibitor. The mechanism of action of flutamide is as an Androgen Receptor Antagonist. Flutamide is a nonsteroidal antiandrogen that acts by binding to and ...

Drugs (A - Z)

Fludarabine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Fludarabine is a purine analog and antineoplastic agent used in the therapy of chronic lymphocytic leukemia (CLL) and in immunosuppressive regimens in preparation for hematopoietic cell ...

Drugs (A - Z)

Fedratinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Fedratinib is an orally bioavailable, small-molecule, ATP-competitive inhibitor of Janus-associated kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential ...

Drugs (A - Z)

Mobocertinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Mobocertinib is an orally available inhibitor of human epidermal growth factor receptor (EGFR) exon 20 insertion mutations, with antineoplastic activity. Mobocertinib is a Kinase Inhibitor. The ...

Drugs (A - Z)

Raloxifene – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Raloxifene is a selective benzothiophene estrogen receptor modulator (SERM). Raloxifene binds to estrogen receptors (ER) as a mixed estrogen agonist/antagonist; it displays both an ...

Drugs (A - Z)

Asparaginase Erwinia chrysanthemi

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Asparaginase Erwinia chrysanthemi is an asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma. ...

Drugs (A - Z)

Erlotinib Hydrochloride – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Erlotinib is a tyrosine kinase receptor inhibitor that is used in the therapy of advanced or metastatic pancreatic or non-small cell lung cancer. Erlotinib therapy is associated with transient ...

Drugs (A - Z)

Vismodegib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Vismodegib is an orally bioavailable, small molecule inhibitor of SMO and the Hedgehog (Hh) pathway, with potential antineoplastic activity. Upon oral administration, vismodegib targets binds ...

Drugs (A - Z)

Enzalutamide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Enzalutamide is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported ...

Drugs (A - Z)

Entrectinib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Entrectinib is an orally bioavailable inhibitor of the tyrosine kinases tropomyosin receptor kinases (Trk) A, B, and C, C-ros oncogene 1 (ROS1) and anaplastic lymphoma kinase (ALK), with ...

Drugs (A - Z)

Enfortumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers. It is comprised of a fully human monoclonal ...

Drugs (A - Z)

Enasidenib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Enasidenib is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity. Upon administration, ...

Drugs (A - Z)

Emapalumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Emapalumab (em" a pal' ue mab) is a recombinant, human IgG1 monoclonal antibody to gamma interferon, which inhibits its binding to cell surface interferon receptors and the subsequent activation of ...

Drugs (A - Z)

Tagraxofusp-Erzs – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Tagraxofusp ERZS is a CD123-directed cytotoxin used to treat blastic plasmacytoid dendritic cell neoplasm. Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human ...

Drugs (A - Z)

Eltrombopag Olamine – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Eltrombopag is an orally active thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the platelet thrombopoietin receptor (TPO-R or ...

Drugs (A - Z)

Elotuzumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Elotuzumab is an antineoplastic agent and SLAMF7-directed immunostimulatory antibody used for the treatment of refractory multiple myeloma in combination with other antineoplastic agents. Elotuzumab ...

Drugs (A - Z)

Rasburicase – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Rasburicase is a recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma. Rasburicase is a recombinant urate-oxidase ...

Drugs (A - Z)

Duvelisib – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Duvelisib is an orally bioavailable, highly selective, and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating ...

Drugs (A - Z)

Durvalumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Durvalumab is an antineoplastic monoclonal antibody used to treat urothelial carcinoma and locally advanced, unresectable non-small cell lung cancer. It is a human immunoglobulin G1 kappa (IgG1κ) ...

Drugs (A - Z)

Dostarlimab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Dostarlimab is an anti-PD-1 monoclonal antibody used in the treatment of mismatch repair deficient endometrial cancers. Dostarlimab is a monoclonal antibody used as a medication for the treatment ...

Drugs (A - Z)

Dinutuximab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Dinutuximab is an immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to ...

Drugs (A - Z)

Dexrazoxane Hydrochloride – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Dexrazoxane Hydrochloride is the hydrochloride salt of a bisdioxopiperazine with iron-chelating, chemoprotective, cardioprotective, and antineoplastic activities. After hydrolysis to an active form ...

Drugs (A - Z)

Denosumab – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Denosumab is a RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures. Denosumab is a novel, fully human IgG2 monoclonal antibody specific ...

Drugs (A - Z)

Denileukin diftitox – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Denileukin diftitox is a recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 ...

Drugs (A - Z)

Degarelix – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Degarelix is a parenterally administered, gonadotropin-releasing hormone (GnRH) antagonist that effectively blocks androgen production and is used to treat advanced prostate cancer. Degarelix ...

Drugs (A - Z)

Defibrotide – Uses, Dosage, Side Effects, Interaction

Dr. Harun Ar Rashid, MD - Arthritis, Bones, Joints Pain, Trauma, and Internal Medicine Specialist

Defibrotide is a mixture of single-stranded oligodeoxyribonucleotides derived from the intestinal mucosa of pigs, with anti-thrombotic, thrombolytic, and fibrinolytic activities. Upon ...