User Posts: Dr. Leslie A Andritsos, MD -Hematology and Oncology
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Transient T‑Cell Lymphopenia
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Transient T‑cell lymphopenia means a temporary fall in the number of T lymphocytes (the white blood cells that coordinate and direct immune responses) in the ...

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CD8 Predominant Lymphopenia
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CD8-predominant lymphopenia is a type of lymphopenia where the CD8+ T-cell subset falls below normal levels while other lymphocyte populations remain ...

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Isolated (Idiopathic) Isolated CD4 Lymphopenia
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Isolated CD4 lymphopenia—also called idiopathic CD4 lymphocytopenia (ICL)—is a rare immune condition in which a person has abnormally low levels of CD4⁺ ...

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Secondary B‑cell lymphopenia
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Secondary B‑cell lymphopenia is a condition in which your body has too few B lymphocytes (a type of white blood cell) because of another illness or treatment. ...

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Primary B‑Cell Lymphopenia
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Primary B‑cell lymphopenia is a rare inherited immunodeficiency in which a person’s body cannot make enough B lymphocytes—white blood cells responsible for ...

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B‑cell lymphopenia
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B‑cell lymphopenia occurs when the number of B cells in the blood drops below the normal range, typically fewer than 100–500 cells per microliter in adults. ...

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T‑Cell Lymphopenia
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T‑cell lymphopenia means a person has too few T lymphocytes (T cells) in the blood and often in lymphoid tissues. T cells are white blood cells that coordinate ...

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Combined B‑ and T‑Cell Lymphopenia
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Combined B‑ and T‑Cell Lymphopenia is an immunodeficiency in which both B lymphocytes (responsible for antibody production) and T lymphocytes (responsible for ...

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Selective B‑Cell Lymphopenia
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Selective B‑cell lymphopenia means the number of B lymphocytes (B cells) in the blood is lower than normal, while other white blood cell types (like many T ...

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Selective T‑cell Lymphopenia
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Selective T‑cell lymphopenia means a person has too few T lymphocytes (T cells) in the blood and tissues, while other white cells may be normal or less ...

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Chronic Lymphopenia
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Lymphopenia means your blood has fewer lymphocytes than normal. Lymphocytes are white blood cells that run your immune system—mainly T cells, B cells, and NK ...

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Acute Lymphopenia
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Acute lymphopenia means your lymphocyte count drops suddenly below the normal range, usually because of a short‑term illness, drug effect, or stress response. ...

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Lymphopenia
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Lymphopenia means your blood has too few lymphocytes, which are the white blood cells that run much of your immune system. The main lymphocyte types are T ...

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Persistent (Long‑Term) Lymphocytopenia
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Lymphocytopenia (also called lymphopenia) means your blood has too few lymphocytes, the white blood cells that drive immune defense (T cells, B cells, and ...

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Transient (Short‑Term) Lymphocytopenia
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Transient lymphocytopenia is a temporary drop in the number of lymphocytes—key white blood cells that help fight infections—in your bloodstream. Clinically, ...

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Secondary (Acquired) Lymphocytopenia
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Secondary (acquired) lymphocytopenia is a condition in which the number of lymphocytes—white blood cells essential for adaptive immunity—falls below normal ...

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Primary (Inherited) Lymphocytopenia
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Primary (inherited) lymphocytopenia means a person is born with a genetic change that leads to too few lymphocytes—the white blood cells (T cells, B cells, and ...

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NK‑cell Lymphocytopenia
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Natural killer (NK) cells are a type of white blood cell that patrols the body, identifying and destroying virus‑infected cells and tumor cells. When NK cells ...

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B‑cell Lymphocytopenia
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B‑cell lymphocytopenia means the number of B lymphocytes (B cells) in the blood is lower than normal for a person’s age. B cells are a type of white blood cell ...

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T‑cell Lymphocytopenia
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T‑cell lymphocytopenia means the body has too few T lymphocytes (T cells) in the blood. T cells are white blood cells that coordinate the immune system and ...

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Physiologic Lymphocytopenia
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Lymphocytopenia (also called lymphopenia) means a lower‑than‑normal number of lymphocytes in the blood. Lymphocytes are white blood cells that power your ...

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Physiologic Lymphocytopenia
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Physiologic lymphocytopenia is a normal, transient drop in circulating lymphocyte counts that occurs in healthy individuals under non‑pathologic conditions. ...

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Production / Destruction-Dominant Lymphocytopenia
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Production‑dominant lymphocytopenia occurs when the bone marrow cannot produce enough lymphocytes. Lymphocytes are white blood cells vital for fighting ...

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Dilutional Lymphocytopenia
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Dilutional lymphocytopenia is a specific form of lymphopenia (also called lymphocytopenia) in which the absolute number of lymphocytes in the blood is lowered ...

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Redistribution‑Dominant Lymphocytopenia
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Redistribution‑dominant lymphocytopenia is a condition in which the number of lymphocytes (a key type of white blood cell) in the bloodstream falls because ...

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Relative Lymphocytopenia
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Relative lymphocytopenia is a blood‐test finding in which lymphocytes—the white blood cells critical for fighting infections—make up a lower percentage of your ...

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Clonal (Malignant) Lymphocytosis
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Lymphocytosis means a high number of lymphocytes (a type of white blood cell) in the blood. Many short‑lived infections can raise lymphocytes for a few days or ...

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Reactive (Benign) Lymphocytosis
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Reactive (benign) lymphocytosis is a condition in which your body has an unusually high number of lymphocytes—white blood cells tasked with fighting ...

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Lymphocytopenia
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Lymphocytopenia means you have lower than normal lymphocytes in your blood. Lymphocytes are a type of white blood cell (mainly T cells, B cells, and NK cells) ...

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Severe Low Lymphocytes (Severe Lymphocytopenia)
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Severe low lymphocytes—also known as severe lymphocytopenia—is a condition in which the lymphocyte count in the blood falls well below the normal range ...

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Moderate Low Lymphocytes Than Normal
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Lymphocytes are a type of white blood cell essential for fighting infections and regulating the immune response. When the absolute lymphocyte count (ALC) falls ...

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Mild Low Lymphocytes Than Normal
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Mild lymphocytopenia, sometimes called mild lymphopenia, refers to a slight decrease in the number of lymphocytes in the bloodstream. Lymphocytes are a type of ...

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Low Lymphocytes
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Low lymphocytes, or lymphopenia, refers to an abnormally low number of lymphocytes—a type of white blood cell crucial for immune defense—in the bloodstream. ...

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NK‑cell Lymphocytosis
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Natural killer (NK) cells are a type of white blood cell critical to your body’s first line of defense against infected or cancerous cells. They act without ...

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T‑cell Lymphocytosis
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Lymphocytosis means there are more lymphocytes than usual in the blood. Lymphocytes are a type of white blood cell. They include T cells, B cells, and NK ...

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Mantle Cell Lymphocytosis
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Mantle cell lymphocytosis refers to an abnormal increase in malignant B-lymphocytes originating from the “mantle zone” of lymph nodes—a pattern characteristic ...

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Monoclonal B‑cell Lymphocytosis
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Monoclonal B‑cell lymphocytosis (MBL) is a blood condition in which a small, clonal population of B‑lymphocytes—white blood cells that normally help fight ...

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B‑cell Lymphocytosis
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B‑cell lymphocytosis (also called monoclonal B‑cell lymphocytosis, or MBL) means your body has too many identical B‑cells in the blood. These cells come from ...

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Chronic (Persistent) Lymphocytosis
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Chronic lymphocytosis is a condition where your blood contains too many lymphocytes— a type of white blood cell—over a long period. Normally, lymphocytes make ...

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Acute or Transient Lymphocytosis
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Acute or transient lymphocytosis refers to a temporary increase in the absolute lymphocyte count (ALC) in peripheral blood above the normal range (usually ...

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Clonal (Primary) Lymphocytosis
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Clonal (Primary) Lymphocytosis is a blood disorder characterized by an abnormally high number of lymphocytes—white blood cells that play a critical role in the ...

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Reactive (Secondary) Lymphocytosis
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Reactive (secondary) lymphocytosis is a condition in which the number of lymphocytes—a type of white blood cell vital for fighting infections—rises above its ...

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Absolute Lymphocytosis
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Absolute lymphocytosis occurs when the number of lymphocytes in the blood rises above normal. Lymphocytes are a type of white blood cell that help your body ...

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Relative Lymphocytosis
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Relative lymphocytosis is a laboratory finding in which lymphocytes—one of the major types of white blood cells—make up more than 40% of the total white blood ...

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Lymphocytosis
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Lymphocytosis means your blood has more lymphocytes than usual. Lymphocytes are a kind of white blood cell that help you fight infections and control immune ...

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Severe Higher Lymphocytes Than Normal
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Lymphocytes are a type of white blood cell crucial for fighting infections and maintaining immune balance. In healthy adults, lymphocyte counts typically range ...

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Moderately Higher Lymphocytes 
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Moderate lymphocytosis refers to an increase in the absolute lymphocyte count (ALC) above the normal upper limit (approximately 4.0 × 10⁹/L in adults) but ...

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Mild Higher Lymphocytes Than Normal (Mild Lymphocytosis)
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Lymphocytes are a type of white blood cell that help protect your body against infections and other foreign invaders. In adults, a normal lymphocyte count is ...

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Higher Lymphocytes Than Normal
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Lymphocytes are a type of white blood cell that help your immune system recognize, remember, and attack germs and abnormal cells. They include B cells (make ...

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Congenital Basopenia 
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Basophils are a rare type of white blood cell (usually ≤1% of circulating leukocytes). They help defend against parasites and take part in allergic ...

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Acquired Basopenia 
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Acquired basopenia is a medical condition characterized by an abnormally low level of basophils—a type of white blood cell—in the circulation. Normally, ...

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Persistent Basopenia
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Basopenia means a low number of basophils (a type of white blood cell) in the blood. Basophils are the least common granulocytes and normally make up about ...

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Transient Basopenia
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Basopenia means your basophil count is lower than the reference range on a complete blood count (CBC) with differential. Basophils are allergy‑ and ...

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Relative Basopenia
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Relative basopenia is a laboratory finding where the percentage of basophils—a type of white blood cell that helps control allergic and inflammatory ...

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Basopenia
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Basopenia is a laboratory finding defined by an abnormally low count of basophils in the peripheral blood, typically below 0.01 × 10⁹ cells per liter. ...

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Absolute Basopenia
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Absolute basopenia is a rare hematologic finding characterized by a near‐total absence of basophils—one of the five types of white blood cells that help ...

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Severe Low Basophils Means
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Basophils are the rarest white blood cells. They usually make up less than 1% of your white cells. In absolute numbers, a typical healthy range is roughly ...

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What Does “Moderate Low Basophils” Mean?
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Basophils are a type of white blood cell (leukocyte) that make up less than 1% of your total white blood cell count. They play crucial roles in immune ...

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Mild Low Basophils (Mild Basopenia)
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Basophils are one of your white blood cells. They are few in number—normally less than 1% of all white blood cells—and carry tiny granules filled with ...

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Low Basophils
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Basophils are one of the five kinds of white blood cells. They are rare—usually less than 1% of all white cells in your blood. Even though they are few, they ...

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Congenital (Juvenile) Hypothyroid Myxedema
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Congenital (Juvenile) Hypothyroid Myxedema is a form of severe, long‐standing hypothyroidism that presents early in life—either at birth (congenital) or in ...

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Decompensated Myxedema
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Decompensated myxedema, often termed myxedema coma, represents the most severe and life‐threatening manifestation of longstanding, untreated hypothyroidism. In ...

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Chronic Compensated Myxedema
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Chronic compensated myxedema is a form of long‑standing, severe hypothyroidism in which the body’s adaptive mechanisms have so far maintained near‑normal vital ...

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Central (Secondary) Hypothyroid Myxedema
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Central (secondary) hypothyroidism means your thyroid gland is underactive because the control center in the brain—the pituitary gland (secondary) or the ...

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Primary Hypothyroid Myxedema
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Primary hypothyroid myxedema is a condition arising from long-standing, untreated primary hypothyroidism—where the thyroid gland itself fails—leading to ...

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Tongue Myxedema
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Tongue myxedema refers to the non‐pitting swelling and thickening of the tongue caused by the pathological accumulation of mucopolysaccharides ...

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Laryngeal Myxedema
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Laryngeal myxedema is a rare but important complication of severe or prolonged hypothyroidism. In this condition, low thyroid hormone levels lead to the ...

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Localized Myxedema
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Localized myxedema is a skin condition linked to autoimmune thyroid disease—most often Graves’ disease. In this disorder, the skin (usually over the fronts of ...

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Myxedema Crisis
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Myxedema crisis is the most extreme, life‑threatening form of severe hypothyroidism. In simple terms, the thyroid has been underactive for so long, and to such ...

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Myxedema Coma
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Myxedema coma is the most severe, life‑threatening form of hypothyroidism (very low thyroid hormone). It is an endocrine emergency marked by multi‑organ ...

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Thyroid Dermopathy
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Thyroid dermopathy, also known as pretibial myxedema or Graves’ dermopathy, is an autoimmune manifestation of Graves’ disease characterized by the accumulation ...

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Pretibial Myxedema
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Pretibial myxedema, also known as thyroid dermopathy, is a skin condition characterized by thickening and swelling of the skin over the shins. It most often ...

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Generalized (Hypothyroid) Myxedema
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Generalized myxedema is the most severe form of long-standing, untreated hypothyroidism. In simple English, it means your body isn’t making enough thyroid ...

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Myxedema
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Myxedema (pronounced miks-uh-DEE-muh) is a severe form of hypothyroidism in which chronically low thyroid hormone levels lead to abnormal accumulation of ...

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Persistent Basophilia
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Basophils are one of the five main types of white blood cells. They are small cells packed with granules that carry chemicals such as histamine, heparin, and ...

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Transient Basophilia
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Basophilia means the number of basophils—one of your white blood cell types—has risen above the normal range in your bloodstream. Basophils help your body ...

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Secondary (Reactive) Basophilia
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Secondary (reactive) basophilia is a condition where the body produces too many basophils— a type of white blood cell— in response to another disease, ...

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Primary (Clonal) Basophilia
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Basophilia means a higher‑than‑normal number of basophils in the blood. Basophils are a kind of white blood cell (part of the immune system). They carry tiny ...

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Absolute Basophilia
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Basophils are a small type of white blood cell made in your bone marrow. They circulate in the blood and carry tiny packets of chemicals such as histamine, ...

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Relative Basophilia
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Relative basophilia is a laboratory finding in which basophils—one of the five types of white blood cells—make up a higher percentage of the total white blood ...

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What Does “Severe High Basophils” Means
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Basophils are one of the five main types of white blood cells. They are very few in number in healthy people, but they have powerful chemicals inside them—such ...

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What “Moderate High Basophils” Usually Means
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Basophils are one of the five major types of white blood cells. They are small cells made in the bone marrow that travel in the blood and quickly enter tissues ...

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What Does “Mild High Basophils” Mean?
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Basophils are one of the five main types of white blood cells. They are very small in number compared with neutrophils and lymphocytes, but they play an ...

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High Basophils Than Normal Value
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High basophils, or basophilia, occur when the number of basophils in your blood exceeds the normal range (greater than about 200 cells per microliter). ...

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Myelodysplastic Syndromes (MDS)
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Myelodysplastic Syndromes (MDS) are a group of blood and bone marrow disorders in which the bone marrow does not produce enough healthy blood cells. In simple ...

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Megaloblastic Pancytopenia
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Megaloblastic pancytopenia is a condition where all three major blood cell lines are low—red blood cells (causing anemia), white blood cells (raising infection ...

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Hypersplenism-Related Pancytopenia
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Hypersplenism-related pancytopenia is a condition in which an overactive spleen causes a significant drop in all three main types of blood cells—red blood ...

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Megaloblastic Pancytopenia
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Megaloblastic pancytopenia is a condition where the bone marrow cannot make healthy blood cells properly because DNA building in the cells is faulty. ...

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Refractory Cytopenia with Multilineage Dysplasia (RCMD)
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group of disorders caused by malfunctioning bone marrow. In RCMD, the bone marrow doesn’t make enough healthy blood cells—specifically red blood cells, white ...

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Refractory Anemia with Excess Blasts
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RAEB is a bone‑marrow disorder in which the factory that makes blood cells (the marrow) is damaged and produces too few healthy blood cells. The word ...

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Refractory Anemia with Ring Sideroblasts (RARS)
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Refractory anemia with ring sideroblasts—often shortened to RARS—is a bone marrow disorder that belongs to the family of conditions called myelodysplastic ...

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Autoimmune Pancytopenia
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Autoimmune Pancytopenia is a rare but serious condition where your immune system attacks your own bone marrow. The bone marrow is the soft, spongy tissue ...

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Myelophthisic Pancytopenia
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Myelophthisic pancytopenia means all three blood cell lines are low (red cells, white cells, and platelets) because the bone marrow space has been physically ...

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Aplastic Marrow Failure
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Aplastic marrow failure is a serious condition where the bone marrow stops making enough blood cells. The bone marrow is the soft “factory” inside your bones ...

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Hypoplastic Marrow Failure
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In hypoplastic marrow failure, the factory floor becomes nearly empty (the medical word is “hypocellular”). The stem cells and support cells that should be ...

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Nutritional Deficiency Pancytopenia
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Pancytopenia means all three major blood cell lines are low at the same time: red blood cells (carry oxygen), white blood cells (fight infection), and ...

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Immune Mediated pancytopenia
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Pancytopenia means “all-cell poverty.” Doctors give that name when blood tests show low hemoglobin, low white-blood-cell count, and low platelet count ...

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Hypoplastic Pancytopenia
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Hypoplastic pancytopenia is a condition characterized by a reduction in all three blood cell lines—red blood cells, white blood cells, and platelets—due to an ...

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Infiltrative Pancytopenia
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Pancytopenia means that all three major blood cell lines are low at the same time: red blood cells (which carry oxygen), white blood cells (which fight ...

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Aplastic Pancytopenia
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Aplastic pancytopenia, often called aplastic anemia, is a rare but serious blood disorder. “Aplastic” means “failure to form,” and “pancytopenia” means “low ...

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Congenital Immunodeficiency Disorders
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Congenital immunodeficiency disorders are conditions you are born with that make the immune system too weak, unbalanced, or wrongly wired to fight infections ...

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Myelodysplastic Neoplasms
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Myelodysplastic neoplasms (previously called myelodysplastic syndromes or MDS) are a group of clonal blood disorders in which the bone marrow produces blood ...

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Myelodysplastic Syndromes
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Myelodysplastic syndromes—sometimes shortened to “MDS” or called “myelodysplastic neoplasms”—are a family of blood-forming stem-cell cancers that start inside ...

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Cytokine Release Syndrome (CRS)
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Cytokine Release Syndrome (CRS) is an intense, whole‑body inflammatory reaction caused by a sudden, excessive burst of immune signaling proteins called ...

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Inflammatory Response Syndrome
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Inflammatory Response Syndrome refers to a whole‑body (“systemic”) reaction of the immune and stress systems to a serious trigger. The trigger can be an ...

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Inflammatory Response Syndrome
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Inflammatory Response Syndrome refers to a whole‑body (“systemic”) reaction of the immune and stress systems to a serious trigger. The trigger can be an ...

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Bone Marrow Suppression (Myelosuppression)
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Bone marrow suppression, also known as myelosuppression, occurs when the bone marrow’s ability to produce red blood cells, white blood cells, and platelets is ...

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Pancytopenia
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Pancytopenia is a serious blood condition where all three major types of blood cells — red blood cells (RBCs), white blood cells (WBCs), and platelets — are ...

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Relative Eosinopenia
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Relative eosinopenia means a condition where the percentage of eosinophils (a type of white blood cell) is lower than usual in relation to other white blood ...

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Absolute Eosinopenia
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Absolute eosinopenia is a hematological finding characterized by a virtual absence of eosinophils in the peripheral blood. Clinically, it is often defined as ...

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Chronic Eosinopenia
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Chronic eosinopenia is a long-term condition in which a person has persistently lower-than-normal levels of eosinophils in their blood. Eosinophils are a type ...

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Transient Eosinopenia
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Transient eosinopenia is a short-term or temporary drop in the number of eosinophils in the blood. Eosinophils are a type of white blood cell that help the ...

Browsing All Comments By: Dr. Leslie A Andritsos, MD -Hematology and Oncology
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