Autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases.[rx] Nearly any body part can be involved.[rx] Common symptoms include low-grade fever and feeling tired.[rx] Often symptoms come and go.[rx]
Synonyms: APS 1, Autoimmune polyendocrine syndrome type 1, Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), Hypoadrenocorticism with hypoparathyroidism and superficial moniliasis, Autoimmune polyendocrinopathy syndrome type 1, Polyglandular autoimmune syndrome type 1, PGA 1, PGA-I, Whitaker syndrome, Type I Polyglandular Autoimmune Syndrome, Autoimmune polyglandular syndrome type I
Synonyms: Autoimmune polyendocrine syndrome type 3, APS3, Polyglandular autoimmune syndrome type 3, PAS3, Autoimmune polyglandular syndrome type III, PGA-III
Synonyms: Eosinophilic cellulitis, Bullous cellulitis with eosinophilia, Wells’ syndrome
Symptoms of Autoimmune Diseases
Autoimmune diseases have a wide variety of different effects. They do tend to have one of three characteristic pathological effects which characterize them as autoimmune diseases:[rx]
Damage to or destruction of tissues
Altered organ growth
Altered organ function
It has been estimated that autoimmune diseases are among the leading causes of death among women in the United States in all age groups up to 65 years.[rx] A substantial minority of the population suffers from these diseases, which are often chronic, debilitating, and life-threatening. There are more than 80 illnesses caused by autoimmunity.[rx]
Causes of Autoimmune Diseases
The cause is generally unknown.[rx] Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors.[rx] There are more than 100 autoimmune diseases.[rx]Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves’ disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.[rx][rx]
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