Autosomal recessive cerebellar ataxia due to GBA2 deficiency is a rare, inherited brain disorder. It mainly affects the cerebellum, the part of the brain that ...

Autosomal recessive neuromyotonia and axonal neuropathy is a rare, inherited nerve disease. It starts in childhood or the teen years. It damages the axons (the ...

Autosomal dominant slowed nerve conduction velocity means a person inherits (from one parent) a gene change that damages the myelin covering of peripheral ...

Optic atrophy type 8 (OPA8) is a hereditary eye and nerve condition where the optic nerves slowly waste away, causing vision to decline—usually starting in ...

Autosomal dominant sleep-related hypermotor (hyperkinetic) epilepsy (ADSHE; formerly ADNFLE) is an inherited epilepsy where brief, sudden, often repetitive ...

Distal renal tubular acidosis (often shortened to “distal RTA” or “type 1 RTA”) is a kidney problem where the last part of the kidney tubule (the distal tubule ...

Charcot-Marie-Tooth neuropathy type 2W (CMT2W) is a rare, inherited nerve disorder. It mainly damages the long “wires” of the peripheral nerves—called ...

Charcot–Marie–Tooth (CMT) is a group of inherited nerve disorders that slowly damage the long nerves of the arms and legs. These nerves carry signals that let ...

Autosomal dominant hereditary ataxia is a group of inherited brain disorders where the main problem is loss of balance and coordination because parts of the ...

Autoimmune enteropathy is a rare disease where the immune system attacks the lining of the small intestine. The attack makes the villi (tiny finger-like ...

Atypical progressive supranuclear palsy (PSP) is a brain disease where certain cells slowly get damaged by an abnormal protein called 4-repeat tau. This damage ...

Atypical juvenile parkinsonism means parkinsonism that starts in children, teens, or very young adults and does not look like the “typical” adult Parkinson’s ...

Spinocerebellar ataxia is an umbrella term for a large group of mostly inherited brain disorders that primarily damage the cerebellum (the coordination center) ...

Ataxia-Telangiectasia (A-T) variant is a rare, inherited condition. It affects the brain (especially the cerebellum), the immune system, the lungs, and cancer ...

Arachnoiditis means the thin middle lining around your spinal cord—the arachnoid membrane—gets inflamed. This lining normally protects the nerves and lets ...

Chronic arachnoiditis means long-lasting inflammation and scarring of the arachnoid, a thin covering around the spinal cord and nerve roots. Over time, the ...

Adhesive arachnoiditis is a long-lasting inflammation and scarring problem of the arachnoid—the thin, spider-web-like layer that covers your spinal cord and ...

Arachnoiditis is long-lasting inflammation of the arachnoid membrane, which is one of the thin coverings that protect the spinal cord and spinal nerves. When ...

An arachnoid cyst is a pocket (sac) filled with clear fluid that looks and behaves like cerebrospinal fluid (CSF), the liquid that cushions the brain and ...

Aprosencephaly–cerebellar dysgenesis (ACD) is a very rare, severe brain malformation present from early pregnancy. In ACD, the baby’s forebrain ...