ALG1 Congenital Disorder of Glycosylation (ALG1-CDG)
ALG1-CDG is a rare, inherited condition that affects how the body attaches sugar chains to proteins and fats. This process is called glycosylation. The ALG1 gene makes an enzyme (a ...
Rx Blood, Metabolism, and Infectious Diseases (A – Z)
Granulocytopenic Disorder
A granulocytopenic disorder means the number of granulocytes in the blood is lower than normal. Granulocytes are a group of white blood cells that fight germs. They include neutrophils, eosinophils, ...
Agranulocytosis
Agranulocytosis is a very severe form of neutropenia. Neutrophils are a type of white blood cell that fight germs. In agranulocytosis, the number of neutrophils becomes extremely low. Doctors measure ...
African Iron Overload
African iron overload is a condition in which too much iron slowly builds up in the body, especially in people from parts of sub-Saharan Africa and their descendants. The extra iron comes from two ...
Nocardiosis
Nocardiosis is an infection caused by Nocardia bacteria. These are thin, branching, gram-positive bacteria that live in soil, dust, and water. They are “aerobic,” which means they grow in the ...
Aerobic Actinomyces Infection (Better Called Aerobic Actinomycete Infection)
Species in the genus Actinomyces are classically anaerobic or microaerophilic—they prefer little or no oxygen—and cause actinomycosis. By contrast, the organisms that live in oxygen and look ...
Types of Acute Lymphocytic Leukemia
Acute lymphocytic leukemia is a fast-growing blood cancer. It starts in the bone marrow, which is the soft center inside bones. The marrow makes new blood cells. In ALL, a very early lymphocyte (a ...
Hybrid Acute Leukemia
Hybrid acute leukemia is a fast-growing blood cancer where the blast cells (immature cells) show features of more than one lineage at the same time. In simple words, the leukemia cells look and act ...
Acute Leukemia of Indeterminate Lineage
Acute leukemia of indeterminate/ambiguous lineage (ALIL/ALAL) is a rare, fast-growing blood cancer that starts in the bone marrow but does not fit cleanly into the usual leukemia types (acute myeloid ...
Acute Leukemia of Ambiguous Lineage
Acute leukemia of ambiguous lineage (ALAL) is a rare, fast-growing blood cancer where the leukemia cells show features of more than one blood cell family at the same time. In most acute leukemias, ...
Acquired Primary Erythrocytosis
Acquired primary erythrocytosis means your body has too many red blood cells because of a problem that starts inside the bone marrow itself, and this problem is acquired (it happens during life and ...
Erythropoietin Stimulating Agents
Erythropoietin (EPO) is a glycoprotein hormone produced by the peritubular cells of the renal cortex. This hormone stimulates red blood cell production in response to low partial pressure of ...
Red Blood Cell Destruction
Early destruction of red blood cells (RBCs), also known as hemolysis, leads to hemolytic anemia, a condition where RBCs are destroyed faster than the body can replace them. This premature ...
Combined Monocytopenia
Combined monocytopenia refers to a condition in which a person has a persistently low number of monocytes in the blood—often together with deficiencies or dysfunctions in other immune or blood cell ...
Isolated Monocytopenia
Isolated monocytopenia means a person has a lower-than-normal number of monocytes in the blood, and this decrease is not accompanied by major abnormalities in the other white blood cells. Monocytes ...
Persistent Monocytopenia
Monocytes are a type of white blood cell made in the bone marrow. They circulate in the blood for about 1–3 days, then move into tissues and become macrophages and dendritic cells. These cells help ...
Relative Monocytopenia
Relative monocytopenia means the percentage of monocytes is low compared with the other white cells, but the absolute monocyte number can still be normal. In most labs, monocytes normally make up ...
Severe Low Monocytes
Monocytes are a type of white blood cell that act as first responders in the immune system. They circulate in the blood, migrate into tissues, and become macrophages or dendritic cells that eat ...
Moderate Low Monocytes
Monocytes are a type of white blood cell made in the bone marrow. They circulate in the blood for about a day, then move into tissues where they mature into macrophages and dendritic cells. These ...
Low Monocytes
Monocytes are a type of white blood cell made in the bone marrow that circulate in the blood and then move into tissues where they become macrophages and dendritic cells. They are vital for the ...
