Weston-Hurst Syndrome
Weston-Hurst syndrome is a sudden, very severe inflammation of the brain’s white matter. It often starts a few days to weeks after a viral or bacterial illness. The body’s immune system becomes ...
Rx Autoimmune, Genetic and Rare Diseases (A – Z)
Acute Necrotizing Hemorrhagic Leukoencephalitis (ANHL)
Acute necrotizing hemorrhagic leukoencephalitis (ANHL) is a very rare, sudden, and severe inflammation of the brain’s white matter. Doctors also call it “Hurst disease” or “acute hemorrhagic ...
Acute Hemorrhagic Leukoencephalitis (AHLE)
Acute hemorrhagic leukoencephalitis (AHLE) is a very rare, very fast-moving disease of the brain. It is a severe form of inflammation that attacks the white matter. “White matter” is the wiring that ...
Fulminant Graft-Versus-Host Disease (GVHD)
Fulminant GVHD is a sudden, very severe form of acute GVHD that happens after a stem-cell or bone-marrow transplant. In GVHD, donor immune cells (mostly T-cells) see the patient’s body as “foreign” ...
Acute Graft-versus-Host Disease (aGVHD)
Acute graft-versus-host disease (aGVHD) is a complication after an allogeneic hematopoietic stem-cell or bone-marrow transplant. Donor immune cells (mainly T cells) see the patient’s tissues as ...
Acute Myeloid Leukaemia M6
Acute myeloid leukaemia M6 is an aggressive blood cancer where very early red-blood-cell precursors (erythroblasts) grow out of control in the bone marrow. These abnormal cells crowd out healthy ...
Acute Erythroblastic Leukaemia
Acute erythroblastic leukaemia is a very rare and aggressive blood cancer. It starts in the bone marrow, where red blood cells are made. In this disease, very immature red cell precursors (called ...
Acute Kernicterus
Acute kernicterus—better called acute bilirubin encephalopathy (ABE)—is a type of brain injury that happens in newborns when unconjugated (indirect) bilirubin rises to toxic levels and crosses the ...
Acute Bilirubin Encephalopathy
Acute bilirubin encephalopathy (ABE) is brain injury in a newborn caused by very high levels of unconjugated (indirect) bilirubin. When bilirubin gets too high, it can cross the immature blood-brain ...
Senescent T-cells–Lymphadenopathy–Immunodeficiency Syndrome
This condition is a rare, inherited immune system disorder in which a signaling switch inside white blood cells (the PI3K-delta pathway) is stuck “too on.” Because of that, T-cells age too fast ...
Activated PI3K-Delta Syndrome (APDS)
Activated PI3K-delta Syndrome (APDS) is a rare, inherited immune system condition. It happens when a key signaling pathway in white blood cells (called the PI3K-delta pathway) is overactive. Because ...
Progressive Myoclonic Epilepsy (PME)
Progressive Myoclonic Epilepsy (PME) is a group of rare genetic epilepsy disorders. They cause myoclonus (sudden jerks), seizures, and over time problems with balance, speech, vision, and thinking. ...
Myoclonus Nephropathy Syndrome
Myoclonus-nephropathy syndrome is a rare genetic disorder in which two problems happen together and often get worse over time. The first problem is a progressive myoclonic epilepsy—sudden, brief ...
Action Myoclonus–Renal Failure (AMRF) Syndrome
AMRF is a very rare inherited disease. It has two big parts that often progress independently: a progressive myoclonic epilepsy (sudden jerks that are triggered by action or intention, plus seizures ...
Madura Foot Due to Actinomadura (Actinomycetoma of the Foot)
Madura foot” is a slow, chronic infection of the foot that starts after tiny breaks in the skin let soil-living germs enter. When the germ is a filament-forming bacterium from the genus Actinomadura, ...
Actinomycotic Mycetoma of Foot
Actinomycotic mycetoma of the foot—often shortened to actinomycetoma—is a chronic, slowly progressive infection of the skin, subcutaneous tissue, and sometimes bone, caused by filamentous, ...
Actinomycotic Madura Foot (Actinomycetoma)
Actinomycotic Madura foot is a slow, long-lasting infection of the skin and deeper tissues of the foot caused by special bacteria called actinomycetes (for example Actinomadura, Nocardia, ...
Actinomycosis
Actinomycosis is a long-lasting bacterial infection. It is caused by Actinomyces bacteria. These bacteria normally live harmlessly in the mouth, throat, gut, and female genital tract. They are ...
Summertime Actinic Lichenoid Eruption (SALE)
Summertime actinic lichenoid eruption (SALE) is a sun-induced, seasonal skin disorder. It is part of the lichenoid family of rashes, which means the top layer of the skin reacts with an “interface” ...
Lichenoid Melanodermatitis
Lichenoid melanodermatitis is an older umbrella label dermatologists used for sun-exposed or photo-accentuated, dark-brown to grey patches and plaques that show a lichenoid (interface) inflammation ...
