Disease A-Z Library

Gastrointestinal, Pelvic & Liver Disease, (A – Z)

Browse plain-English disease and condition guides, including symptoms, causes, diagnosis, treatment options, prevention, and when to seek medical care.

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Diseases A-Z

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Disease A-Z Library

Norwegian Cholestasis

Norwegian cholestasis is an old name for a very rare genetic disease now usually called Aagenaes syndrome or cholestasis-lymphedema (lymphedema) syndrome. It is a condition where...

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Recurrent Jaundice of Pregnancy

Recurrent jaundice of pregnancy is usually the same condition doctors now call intrahepatic cholestasis of pregnancy (ICP). Over time it has also been called jaundice of...

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Gravidic Intrahepatic Cholestasis

Gravidic intrahepatic cholestasis (also called intrahepatic cholestasis of pregnancy, ICP) is a liver problem that happens only in pregnancy. In this condition, the tiny tubes inside...

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Sterol 27-Hydroxylase Deficiency

Sterol 27-hydroxylase deficiency is a rare genetic disease where a gene called CYP27A1 does not work properly. This gene makes an enzyme that helps turn cholesterol...

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Cholestanolosis

“Cholestanolosis” is an older or less common name that usually refers to cerebrotendinous xanthomatosis (CTX), a rare genetic disease where a fat-like substance called cholestanol slowly...

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Cholestanol Storage Disease

Cholestanol storage disease is a rare, inherited metabolic disease in which the body cannot correctly turn cholesterol into normal bile acids in the liver. Because of...

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Cerebrotendinous Cholesterinosis

Cerebrotendinous cholesterinosis, usually called cerebrotendinous xanthomatosis (CTX), is a very rare genetic disease that affects how the body makes bile acids from cholesterol. Because of a...

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Cerebrotendinous Xanthomatosis

Cerebrotendinous xanthomatosis (often shortened to CTX) is a rare inherited disease that affects how the body turns cholesterol into bile acids. Because of a gene problem,...

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Hepatic Vein Obstruction

Hepatic vein obstruction means the blood leaving the liver cannot flow out normally through the hepatic veins into the inferior vena cava (IVC) and then to...

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Unconjugated Bilirubin

Unconjugated bilirubin is a yellow waste pigment that your body makes when it breaks down old red blood cells. First, hemoglobin from red cells becomes biliverdin,...

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Kernicterus of the Newborn

Kernicterus is brain damage caused by very high levels of a yellow substance in the baby’s blood called unconjugated bilirubin. When bilirubin is too high, it...

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Bilirubin Encephalopathy

Bilirubin encephalopathy means brain injury caused by very high levels of unconjugated (indirect) bilirubin in a newborn’s blood. Unconjugated bilirubin can cross into the brain. It...

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Non-Syndromic Biliary Atresia

Non-syndromic biliary atresia is a liver disease in newborn babies. The tiny tubes that carry bile (the bile ducts) become inflamed, scarred, and blocked. Bile cannot...

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