Agranulocytosis is a very severe form of neutropenia. Neutrophils are a type of white blood cell that fight germs. In agranulocytosis, the number of ...

Otocephaly is a very rare birth defect that happens very early in pregnancy. The baby’s lower face does not form in the usual way. The lower jaw (mandible) may ...

Holoprosencephaly–agnathia is a very rare birth defect that affects both the brain and the face. In early pregnancy (about weeks 3–4), the front part of the ...

Dysgnathia complex with agnathia–holoprosencephaly is a very rare birth defect pattern that affects the face and the brain together. “Agnathia” means the lower ...

This is an ultra-rare and typically lethal association of defects—most babies do not survive long after birth. The literature is made up mostly of case reports ...

Agnathia–otocephaly complex is a very rare birth condition where the lower jaw (mandible) is missing or extremely small, and the ears may be fused toward the ...

NK-cell large granular lymphocytic leukemia is a cancer of mature natural killer (NK) white blood cells. These cells become clonal (they come from one abnormal ...

Large Granular Lymphocyte (LGL) Leukemia is a slow-growing blood cancer of mature immune cells called large granular lymphocytes. Most cases involve T-cells ...

Aggressive NK-cell lymphoma is a fast-growing blood cancer that starts from natural killer (NK) cells, a type of white blood cell your body uses to kill ...

NK-cell leukemia is a cancer where the body makes too many abnormal natural killer (NK) cells, a white blood cell that normally helps fight infections and ...

Aggressive NK-cell leukemia (ANKL) is a rare, fast-growing blood cancer that starts from natural killer (NK) cells, a type of white blood cell that normally ...

Peripheral neuropathy means the nerves outside the brain and spinal cord do not work properly. These nerves carry signals for feeling (touch, pain, ...

Hereditary Motor and Sensory Neuropathy with Agenesis of the Corpus Callosum (HMSN/ACC)—also known as Andermann syndrome or ACCPN is a rare, inherited nerve ...

“Corpus callosum agenesis–neuronopathy syndrome” describes a condition where a person is born with a missing or very under-developed corpus callosum (the thick ...

Charlevoix disease is a rare, inherited brain and nerve disorder. It begins most often in childhood. The problem starts in the part of the brain that controls ...

Andermann syndrome is a rare genetic condition that affects both the brain and the nerves in the body. The main brain change is that the corpus callosum, the ...

Agenesis of the corpus callosum with peripheral neuropathy is a rare, inherited brain-and-nerve condition. “Agenesis of the corpus callosum” means the big band ...

Disorder of glycine amidinotransferase (AGAT) activity is a rare, inherited condition where the body cannot make enough creatine, a small energy-carrying ...

Creatine deficiency syndrome is a group of rare, inherited brain energy disorders. In these conditions, the brain cannot make, move, or bring in enough ...

Cerebral Creatine Deficiency Syndromes are rare, inherited brain energy disorders in which the brain cannot make, convert, or transport enough creatine into ...