Primary osteosarcoma is a cancer that starts in the bone itself. The tumor cells are abnormal bone-forming cells. They make a disorganized, immature bone ...

Osteogenic sarcoma, also called osteosarcoma, is a cancer that starts in bone-forming cells. These cancer cells make immature bone (“osteoid”) inside the ...

Osteosarcoma is a cancer that starts in the bone-making cells. These cells normally build the hard mineral part of bone. In osteosarcoma they grow out of ...

Connective tissue disorder due to lysyl hydroxylase-3 deficiency (PLOD3-related disorder) is a rare genetic disease that affects the body’s collagen—the ...

Bone fragility-contractures-arterial rupture-hearing loss syndrome/BCARD syndrome is a very rare, inherited connective-tissue disease. “Connective tissue” is ...

Bone Fragility-Contractures-Arterial Rupture-Deafness (BCARD) Syndrome is a very rare, inherited connective-tissue disease. It happens when both copies of the ...

Bone abnormalities is a problem with how bones are built, shaped, or strengthened. The problem can be present from birth (genetic) or can happen later. Bones ...

Bone fragility with contractures, arterial rupture, and deafness (BCARD) is a rare, inherited connective-tissue disorder. The body’s collagen—the protein that ...

Autosomal recessive lethal chondrodysplasia, round femoral inferior epiphysis (RFIE) type” is a very rare, severe bone-growth disorder seen in newborns and ...

Autosomal recessive lethal chondrodysplasia, round femoral inferior epiphysis type is a severe genetic disorder that affects how bones grow before and after ...

Bone dysplasia, lethal Holmgren type is a very rare, inherited disorder that affects how a baby’s bones grow before birth. The main problems are very short ...

Machupo hemorrhagic fever is a severe viral illness that affects the whole body. The virus is called Machupo virus, an arenavirus. People usually get infected ...

Bolivian hemorrhagic fever is a severe viral illness that happens in parts of Bolivia. The virus that causes it is called Machupo virus. This virus belongs to ...

Opitz trigonocephaly-like syndrome describes a rare group of genetic conditions where a baby is born with a triangular forehead from early fusion of the ...

Oberklaid–Danks syndrome, which is the original/alternate name for Bohring–Opitz syndrome (BOS)—a very rare genetic condition first separated from “Opitz ...

BOS syndrome—a very rare genetic (present at birth) condition, most often caused by new (de novo) changes in the ASXL1 gene. Children have a recognizable ...

Bohring-Opitz syndrome is a very rare genetic condition caused most often by a new (not inherited) change in the ASXL1 gene. Babies usually have trouble ...

Pseudoxanthoma Elasticum-Like Syndrome (PXE-Like Syndrome) is a rare inherited skin and connective-tissue condition that looks very similar to classic ...

Body skin hyperlaxity due to vitamin K-dependent coagulation factor deficiency is a very rare inherited skin and blood-clotting disorder. The skin over the ...

Genuine diffuse phlebectasia is a rare venous malformation. “Phlebectasia” means abnormally enlarged veins. In this condition, the enlargement is diffuse ...