*,*::before,*::after{box-sizing:border-box}body{margin:0;background:var(--rx-bg-color,#fff);color:var(--rx-text-color,#1f2937);font-family:var(--rx-body-font,system-ui,sans-serif);line-height:1.7}h1,h2,h3,h4,h5,h6{color:var(--rx-heading-color,#111827);font-family:var(--rx-heading-font,system-ui,sans-serif);line-height:1.25}a{color:var(--rx-primary-color,#0066cc);text-decoration:none}a:hover{text-decoration:underline}img{max-width:100%;height:auto}.rx-container{width:min(100% - 40px,var(--rx-container-width,1200px));max-width:var(--rx-container-width,1200px);margin-inline:auto}.screen-reader-text{position:absolute;left:-9999px}.screen-reader-text:focus{left:16px;top:16px;z-index:9999;background:#fff;padding:12px;border:2px solid currentColor}.rx-topbar{background:var(--rx-primary-color);color:#fff;padding:8px 0;font-size:14px}.rx-site-header{background:#fff;border-bottom:1px solid #e5e7eb;z-index:50}.rx-sticky-header{position:sticky;top:0}.rx-header-inner{display:flex;align-items:center;gap:20px;min-height:76px}.rx-site-title{font-size:26px;font-weight:800;color:var(--rx-heading-color)}.rx-primary-nav{margin-left:auto}.rx-primary-nav ul{display:flex;gap:18px;list-style:none;margin:0;padding:0}.rx-primary-nav a{font-weight:600;color:var(--rx-heading-color)}.rx-menu-toggle{display:none}.rx-header-actions{display:flex;align-items:center;gap:10px}.rx-header-actions .search-form{display:flex}.rx-header-actions input[type=search]{max-width:180px}.rx-dark-toggle,.rx-back-to-top,.rx-read-more,.search-submit{background:var(--rx-primary-color);color:#fff;border:0;border-radius:8px;padding:9px 12px;cursor:pointer}.rx-breadcrumbs{font-size:14px;margin:22px 0;color:#6b7280}.rx-content-layout{display:grid;grid-template-columns:minmax(0,1fr) 320px;gap:32px;margin:28px 0}.rx-sidebar-left{grid-template-columns:320px minmax(0,1fr)}.rx-sidebar-left .rx-posts-area,.rx-sidebar-left .rx-single-area{order:2}.rx-no-sidebar{display:block}.rx-post-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:24px}.rx-post-card{background:#fff;border:1px solid #e5e7eb;border-radius:16px;overflow:hidden;box-shadow:0 8px 24px rgba(15,23,42,.06)}.rx-card-body{padding:20px}.rx-card-title{font-size:21px;margin:0 0 10px}.rx-entry-meta{display:flex;flex-wrap:wrap;gap:12px;color:#6b7280;font-size:14px;margin:10px 0}.rx-single-area,.rx-page,.rx-content-none{background:#fff;border:1px solid #e5e7eb;border-radius:18px;padding:28px}.rx-entry-header h1{font-size:clamp(32px,5vw,56px);margin-bottom:10px}.rx-featured-image img{border-radius:16px}.rx-entry-content{font-size:18px}.rx-entry-content h2,.rx-entry-content h3{scroll-margin-top:120px}.rx-toc{background:#f8fafc;border:1px solid #e5e7eb;border-radius:14px;padding:18px;margin:22px 0}.rx-toc ol{margin-bottom:0}.rx-medical-box,.rx-medical-disclaimer,.rx-author-box,.rx-related,.rx-faq{border:1px solid #dbeafe;background:#eff6ff;border-radius:14px;padding:18px;margin:22px 0}.rx-medical-box h3{margin-top:0}.rx-author-box{display:flex;gap:18px;align-items:flex-start}.rx-author-box img{border-radius:50%}.rx-share{margin:14px 0;display:flex;gap:12px}.rx-sidebar .widget{background:#fff;border:1px solid #e5e7eb;border-radius:14px;padding:18px;margin-bottom:20px}.rx-site-footer{margin-top:50px;background:#0f172a;color:#e5e7eb;padding:42px 0}.rx-site-footer a,.rx-site-footer h2,.rx-site-footer h3{color:#fff}.rx-footer-widgets{display:grid;grid-template-columns:repeat(4,1fr);gap:24px}.rx-footer-bottom{border-top:1px solid rgba(255,255,255,.15);margin-top:24px;padding-top:24px;display:flex;justify-content:space-between;gap:16px}.rx-back-to-top{position:fixed;right:18px;bottom:18px;display:none}.rx-back-to-top.is-visible{display:block}.rx-header-centered{text-align:center;padding:20px 0}.rx-header-centered .rx-primary-nav ul{justify-content:center;margin-top:14px}.rx-medical-footer{text-align:center}.rx-footer-minimal{text-align:center;padding:24px 0}.rx-archive-header{margin:28px 0}.rx-404{text-align:center;padding:80px 0}body.rx-dark-mode{--rx-bg-color:#0b1220;--rx-text-color:#d1d5db;--rx-heading-color:#fff;background:#0b1220}body.rx-dark-mode .rx-post-card,body.rx-dark-mode .rx-single-area,body.rx-dark-mode .rx-page,body.rx-dark-mode .rx-sidebar .widget,body.rx-dark-mode .rx-site-header{background:#111827;border-color:#243244}body.rx-dark-mode .rx-primary-nav a{color:#fff}

.rx-reading-progress{position:fixed;top:0;left:0;width:100%;height:4px;background:transparent;z-index:99999}.rx-reading-progress span{display:block;width:0;height:100%;background:var(--rx-primary-color,#0066cc);transition:width .12s linear}.admin-bar .rx-reading-progress{top:32px}.rx-medical-article{max-width:100%}.rx-article-hero{padding:10px 0 20px;border-bottom:1px solid #e5e7eb;margin-bottom:24px}.rx-article-title{font-size:clamp(34px,5vw,58px);letter-spacing:-.04em;margin:0 0 16px}.rx-article-meta-panel{display:flex;flex-wrap:wrap;gap:12px 18px;background:#f8fafc;border:1px solid #e5e7eb;border-radius:16px;padding:16px;margin:16px 0 22px;color:#475569}.rx-article-meta-panel span{display:inline-flex;gap:6px;align-items:center}.rx-article-meta-panel em{font-style:normal;color:#64748b}.rx-article-featured-image img{border-radius:22px;box-shadow:0 16px 40px rgba(15,23,42,.12)}.rx-article-toc{background:linear-gradient(135deg,#f8fafc,#eff6ff);border:1px solid #dbeafe;border-radius:18px;padding:22px;margin:24px 0}.rx-article-toc h2{margin-top:0}.rx-article-toc ol{columns:2;gap:30px;margin-bottom:0}.rx-article-toc a{font-weight:700}.rx-toc-level-3{margin-left:18px;font-size:.95em}.rx-article-disclaimer{background:#fff7ed;border:1px solid #fed7aa;border-left:5px solid #f97316;border-radius:16px;padding:18px;margin:24px 0;color:#7c2d12}.rx-medical-section-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px;margin:28px 0}.rx-medical-section-card{background:#fff;border:1px solid #e5e7eb;border-radius:18px;padding:18px;box-shadow:0 10px 28px rgba(15,23,42,.06)}.rx-medical-section-card span{display:inline-block;font-size:12px;font-weight:800;text-transform:uppercase;letter-spacing:.06em;color:var(--rx-primary-color,#0066cc);background:#eff6ff;border-radius:999px;padding:4px 8px}.rx-medical-section-card h3{margin:12px 0 8px;font-size:20px}.rx-medical-entry-content{font-size:18px}.rx-medical-entry-content h2{font-size:clamp(28px,4vw,40px);margin-top:42px;padding-top:10px;border-top:1px solid #e5e7eb}.rx-medical-entry-content h3{font-size:26px;margin-top:30px}.rx-article-faq,.rx-article-references{background:#fff;border:1px solid #e5e7eb;border-radius:18px;padding:22px;margin:30px 0;box-shadow:0 10px 28px rgba(15,23,42,.05)}.rx-article-faq details{border:1px solid #e5e7eb;border-radius:12px;padding:14px;margin:12px 0;background:#f8fafc}.rx-article-faq summary{font-weight:800;cursor:pointer;color:var(--rx-heading-color,#111827)}.rx-article-references{background:#f8fafc}.rx-article-references h2,.rx-article-faq h2{margin-top:0}.rx-related{margin-top:34px}.rx-author-box{margin-top:30px}
@media(max-width:900px){.rx-article-toc ol{columns:1}.rx-medical-section-grid{grid-template-columns:1fr}.rx-article-meta-panel{display:grid}.admin-bar .rx-reading-progress{top:46px}}
body.rx-dark-mode .rx-article-meta-panel,body.rx-dark-mode .rx-article-toc,body.rx-dark-mode .rx-medical-section-card,body.rx-dark-mode .rx-article-faq,body.rx-dark-mode .rx-article-references{background:#111827;border-color:#243244}body.rx-dark-mode .rx-medical-section-card span{background:#172554}body.rx-dark-mode .rx-article-disclaimer{background:#241407;border-color:#7c2d12;color:#fed7aa}body.rx-dark-mode .rx-article-faq details{background:#0b1220;border-color:#243244}


/* RX Theme v5 global options + header system */
.rx-custom-logo{max-height:70px;width:auto;display:block}.rx-branding{display:flex;align-items:center;gap:10px}.rx-branding small{display:block;color:#64748b;font-size:12px;margin-top:2px}.rx-header-style-transparent{background:rgba(255,255,255,.82);backdrop-filter:saturate(180%) blur(14px);position:absolute;left:0;right:0;border-bottom:1px solid rgba(255,255,255,.35)}.rx-header-style-transparent.rx-sticky-header{position:sticky}.rx-header-transparent .rx-site-title,.rx-header-transparent .rx-primary-nav a{color:var(--rx-heading-color,#111827)}.rx-header-style-sticky{box-shadow:0 12px 35px rgba(15,23,42,.08)}.rx-topbar-strong{background:linear-gradient(90deg,var(--rx-primary-color),var(--rx-secondary-color));}.rx-topbar-strong .rx-container{display:flex;align-items:center;justify-content:space-between;gap:16px}.rx-topbar-strong .search-form{display:flex;gap:6px}.rx-mobile-headline{font-size:14px;color:#64748b;padding-top:10px}.rx-header-mobile-first .rx-header-inner{justify-content:space-between}.rx-mobile-nav{border-top:1px solid #e5e7eb}.rx-mobile-nav ul{justify-content:center;padding:12px 0}.rx-footer-columns-1{grid-template-columns:1fr}.rx-footer-columns-2{grid-template-columns:repeat(2,1fr)}.rx-footer-columns-3{grid-template-columns:repeat(3,1fr)}.rx-footer-columns-4{grid-template-columns:repeat(4,1fr)}
body.rx-dark-mode .rx-header-style-transparent{background:rgba(17,24,39,.86);border-color:#243244}body.rx-dark-mode .rx-branding small,body.rx-dark-mode .rx-mobile-headline{color:#cbd5e1}
@media(max-width:900px){.rx-menu-toggle{display:inline-flex;align-items:center;gap:6px}.rx-header-inner{min-height:68px}.rx-primary-nav{display:none;width:100%;margin-left:0}.rx-primary-nav.is-open{display:block}.rx-primary-nav ul{display:block}.rx-primary-nav li{border-top:1px solid #e5e7eb}.rx-primary-nav a{display:block;padding:12px 0}.rx-header-actions .search-form{display:none}.rx-header-centered .rx-primary-nav ul{display:block}.rx-topbar-strong .rx-container{display:block}.rx-footer-widgets,.rx-footer-columns-1,.rx-footer-columns-2,.rx-footer-columns-3,.rx-footer-columns-4{grid-template-columns:1fr}.rx-header-style-transparent{position:relative}}



/* RX Theme v7.1 header spacing fix */
.rx-site-header{border-top:4px solid var(--rx-heading-color,#111827)}
.rx-header-inner{width:min(100% - 40px,var(--rx-container-width,1200px));max-width:var(--rx-container-width,1200px);margin-inline:auto;justify-content:space-between}
.rx-primary-nav{margin-left:20px}
.rx-header-actions{margin-left:auto}
.rx-site-title{white-space:normal;overflow-wrap:anywhere}
@media(max-width:720px){.rx-header-inner{width:min(100% - 28px,var(--rx-container-width,1200px));gap:12px}.rx-site-title{font-size:21px}.rx-header-actions{gap:6px}}