The serum trypsinogen Test (often called serum trypsin, or Immunoreactive trypsin test) can be measured in blood and provides a rough estimation of pancreatic function. Abnormally low levels of serum trypsinogen can be seen in patients with advanced chronic pancreatitis with steatorrhea. Trypsinogen is a substance that is normally produced in the pancreas and released into the small intestine. Trypsinogen is converted to trypsin. Then it starts the process needed to break down proteins into their building blocks (called amino acids).
This test measures levels of trypsin in your blood to see if you have pancreatitis. Your pancreas is an organ in your belly that lies behind your stomach. One of its jobs is to make enzymes that go into your small intestine to help you digest foods. The pancreas can become inflamed (pancreatitis). A test can be done to measure the amount of trypsinogen in your blood.
How the Test is Performed
A blood sample is taken from a vein. The blood sample is sent to a lab for testing.
How to Prepare for the Test
There are no special preparations.
How the Test will Feel
You may feel slight pain or a sting when the needle is inserted to draw blood. Afterward, there may be some throbbing.
Why the Test is Performed
This test is done to detect diseases of the pancreas.
The test is also used to screen newborn babies for cystic fibrosis.
Normal Results
Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
Increased levels of trypsinogen may be due to:
- Abnormal production of pancreatic enzymes
- Acute pancreatitis
- Cystic fibrosis
- Pancreatic cancer
Low or normal levels may be seen in chronic pancreatitis .
Risks
Veins and arteries vary in size so it may be harder to get a blood sample from one person than another. Other slight risks from having blood drawn may include:
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
Considerations
Other tests used to detect pancreas diseases may include:
- Serum amylase
- Serum lipase
FAQ
Dr. Md. Harun Ar Rashid, MPH, MD, PhD, is a highly respected medical specialist celebrated for his exceptional clinical expertise and unwavering commitment to patient care. With advanced qualifications including MPH, MD, and PhD, he integrates cutting-edge research with a compassionate approach to medicine, ensuring that every patient receives personalized and effective treatment. His extensive training and hands-on experience enable him to diagnose complex conditions accurately and develop innovative treatment strategies tailored to individual needs. In addition to his clinical practice, Dr. Harun Ar Rashid is dedicated to medical education and research, writing and inventory creative thinking, innovative idea, critical care managementing make in his community to outreach, often participating in initiatives that promote health awareness and advance medical knowledge. His career is a testament to the high standards represented by his credentials, and he continues to contribute significantly to his field, driving improvements in both patient outcomes and healthcare practices.
