Leukonychia

Leukonychia is a condition in which the nails of the fingers and toes become discolored or white in appearance. There are several types of leukonychia, each with a different cause and appearance. Understanding the different types of leukonychia can help individuals diagnose and treat the condition.

Leukonychia is a condition that causes white spots or streaks on the nails. There are two types of leukonychia: true leukonychia, which is a rare genetic condition, and apparent leukonychia, which is a much more common and typically benign condition. Apparent leukonychia is characterized by the appearance of white spots or streaks on the nails, and it is caused by a variety of factors, including injury, illness, and certain medications.

Types

  1. Total Leukonychia

Total leukonychia is a type of leukonychia in which the entire nail plate is white in appearance. This type of leukonychia is often caused by a nutritional deficiency, such as a lack of biotin, calcium, or zinc. It can also be caused by an underlying medical condition, such as liver disease, or a reaction to certain medications.

  1. Partial Leukonychia

Partial leukonychia is a type of leukonychia in which only a portion of the nail is discolored. This type of leukonychia is often caused by trauma to the nail matrix, the area of the nail that produces new nail cells. Trauma to the nail matrix can cause the nail to grow abnormally, leading to a white appearance in the affected area.

  1. Longitudinal Leukonychia

Longitudinal leukonychia is a type of leukonychia in which the white discoloration runs vertically along the nail. This type of leukonychia is often caused by an injury to the matrix, such as a crush injury or a burn. It can also be caused by certain medical conditions, such as anemia or congenital heart disease.

  1. Transverse Leukonychia

Transverse leukonychia is a type of leukonychia in which the white discoloration runs horizontally across the nail. This type of leukonychia is often caused by a fungal infection, such as onychomycosis. It can also be caused by an underlying medical condition, such as psoriasis or eczema.

  1. Muehrcke’s Lines

Muehrcke’s lines are two white bands that run parallel to each other across the nail. This type of leukonychia is often caused by a low level of protein in the blood, such as in cases of malnutrition or liver disease. It can also be caused by certain medications, such as chemotherapy drugs.

  1. Terry’s Nails

Terry’s nails are nails that are white in appearance, except for a narrow band of pink or red near the tip of the nail. This type of leukonychia is often a sign of an underlying medical condition, such as liver disease, heart disease, or aging.

  1. Leukonychia Punctata

Leukonychia punctata is a type of leukonychia in which small white spots appear on the nails. This type of leukonychia is often caused by a hereditary condition, but it can also be caused by certain medical conditions, such as malnutrition or anemia.

Another type

  1. Traumatic leukonychia: This type of leukonychia is caused by injury to the nail matrix. The injury can be caused by various factors, including tapping the nails with a hard object, manicure or pedicure procedures, or exposure to chemicals. The white discoloration can be seen within a few days of the injury and can persist for several months.
  2. Idiopathic leukonychia: This type of leukonychia is not associated with any underlying medical conditions or causes. It is believed to be a genetic condition, and the white discoloration can be seen in one or more nails. It is more commonly seen in older individuals and can persist for life.
  3. Nutritional leukonychia: This type of leukonychia is caused by a deficiency in essential vitamins and minerals, such as biotin, iron, and zinc. This type of leukonychia is often seen in individuals who follow restrictive diets or have a history of malnutrition. The white discoloration can be seen in all nails and can persist until the underlying nutritional deficiency is treated.

Causes

The causes of this condition can range from simple, harmless conditions to more serious underlying health problems. Here are the main lists of causes of apparent leukonychia:

  1. Nail trauma: Physical injury to the nails can cause white discoloration to appear. This can be due to repeated nail tapping, nail biting, or any other physical trauma to the nails.
  2. Nail infections: Fungal or bacterial infections of the nails can cause white discoloration to appear. These infections can also cause the nails to become brittle and break easily.
  3. Nutrient deficiencies: Deficiencies of nutrients such as iron, calcium, or vitamin B12 can cause white discoloration to appear on the nails. These deficiencies can also cause the nails to become brittle and break easily.
  4. Nail polish: The use of nail polish or other chemical products on the nails can cause white discoloration to appear. These chemicals can weaken the nails and cause them to become brittle, leading to discoloration.
  5. Psoriasis: Psoriasis is a skin condition that can cause white discoloration to appear on the nails. This condition can cause the nails to become thick and brittle, leading to white discoloration.
  6. Lichen planus: Lichen planus is an autoimmune disease that can cause white discoloration to appear on the nails. This condition can also cause the nails to become brittle and break easily.
  7. Systemic diseases: Certain systemic diseases such as anemia, liver disease, or kidney disease can cause white discoloration to appear on the nails. These diseases can cause the nails to become brittle and break easily.
  8. Aging: As people age, the nails can become thinner and more brittle, leading to white discoloration. This can also be due to a reduction in the production of natural oils that keep the nails healthy.
  9. Genetics: Some people may have a genetic predisposition to having white nails, which can be due to a family history of the condition.
  10. Certain medications: Certain medications, such as antimalarials, can cause white discoloration to appear on the nails. These medications can also cause the nails to become brittle and break easily.
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In conclusion, there are many different causes of apparent leukonychia. Some of these causes are harmless and easily treatable, while others may indicate a more serious underlying health problem. If you are experiencing white discoloration on your nails, it is important to consult a doctor to determine the underlying cause and receive appropriate treatment.

Symptoms

The main symptoms of apparent leukonychia include:

  1. White spots or streaks on the nails: This is the most obvious and noticeable symptom of leukonychia. The spots or streaks can be small or large and may be isolated or grouped together.
  2. Brittle or weak nails: Apparent leukonychia can also cause the nails to become brittle or weak, making them more susceptible to breakage and chipping.
  3. Changes in nail shape: In some cases, leukonychia can cause changes in the shape of the nails, such as curling or thickening.
  4. Pain or discomfort: In some cases, leukonychia can cause pain or discomfort in the affected area, especially if the white spots or streaks are caused by injury or illness.
  5. Nail separation from the nail bed: In severe cases, leukonychia can cause the nails to separate from the nail bed, which can lead to pain and difficulty with everyday activities.
  6. Fungal infections: Apparent leukonychia can also increase the risk of fungal infections, as the weakened nails are more susceptible to infection.
  7. Discoloration: In some cases, leukonychia can cause the nails to become discolored, turning yellow or brown.

Apparent leukonychia can be caused by a variety of factors, including:

  1. Injury: One of the most common causes of leukonychia is injury to the nails, such as a blow to the fingertips or repeated exposure to harsh chemicals.
  2. Illness: Certain illnesses, such as malnutrition, anemia, and liver disease, can cause leukonychia.
  3. Medications: Certain medications, such as antimalarials, anticonvulsants, and chemotherapy drugs, can cause leukonychia as a side effect.
  4. Pregnancy: Pregnancy can also cause leukonychia, as the changes in hormones can affect the nails.
  5. Aging: As people age, their nails may become more brittle and prone to leukonychia.
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Apparent leukonychia is typically a benign condition and does not require treatment in most cases. However, if the white spots or streaks are causing pain or discomfort, or if they are a symptom of an underlying medical condition, treatment may be necessary.

Diagnosis

To diagnose the underlying cause of apparent leukonychia, several diagnostic tests may be performed.

  1. Physical examination: A physical examination of the nails is typically the first step in diagnosing apparent leukonychia. The healthcare provider will examine the nails for signs of injury, fungal infections, or other abnormal growth patterns.
  2. Nail clippings: A sample of the affected nails may be taken for laboratory analysis. This sample will be examined under a microscope to determine the presence of any fungal infections or other conditions that may be causing the white spots or streaks.
  3. Blood tests: Blood tests can help determine if there are any underlying medical conditions that may be causing the white spots on the nails. For example, blood tests can be used to measure levels of vitamins, minerals, and other nutrients that are essential for healthy nail growth.
  4. Biopsy: In some cases, a biopsy of the affected nail may be performed to confirm the diagnosis. During a biopsy, a small sample of the nail is removed and examined under a microscope to determine the cause of the white spots.
  5. X-rays: X-rays may be used to determine if there are any underlying bone or joint conditions that may be causing the white spots on the nails. For example, x-rays can be used to diagnose conditions such as osteoporosis or rheumatoid arthritis.
  6. Urine tests: Urine tests can be used to diagnose certain medical conditions that may be causing the white spots on the nails. For example, urine tests can be used to diagnose conditions such as diabetes or kidney disease.
  7. Fungal cultures: Fungal cultures can be used to determine if a fungal infection is causing the white spots on the nails. During a fungal culture, a sample of the affected nail is taken and placed on a special medium to grow any fungal organisms that may be present.
  8. Allergy testing: Allergy testing can be used to determine if an allergy is causing the white spots on the nails. Allergy testing may involve skin tests, blood tests, or both.
  9. Imaging studies: Imaging studies such as MRI or CT scans may be used to determine if there are any underlying medical conditions that may be causing the white spots on the nails. For example, imaging studies can be used to diagnose conditions such as arthritis or tumors.

In conclusion, several diagnostic tests may be performed to diagnose the underlying cause of apparent leukonychia. These tests may include physical examination, nail clippings, blood tests, biopsy, x-rays, urine tests, fungal cultures, allergy testing, and imaging studies. The specific tests that are performed will depend on the individual case and the suspected cause of the white spots on the nails.

Treatment

The main lists of treatments for apparent leukonychia include dietary changes, topical treatments, oral medications, and surgical procedures.

  1. Dietary Changes: One of the most common causes of apparent leukonychia is a deficiency of nutrients such as biotin, zinc, and calcium. Hence, incorporating these essential nutrients into the diet can help to improve the condition. Foods rich in biotin include eggs, yeast, almonds, and whole wheat bread. Foods rich in zinc include oysters, red meat, poultry, and whole grains. Foods rich in calcium include dairy products, leafy greens, nuts, and seeds.
  2. Topical Treatments: Topical treatments can help to improve the appearance of the nails. These treatments include moisturizing creams, nail strengtheners, and antifungal ointments. Moisturizing creams can help to hydrate the nails and prevent further damage. Nail strengtheners can help to prevent breakage and improve the overall health of the nails. Antifungal ointments can help to treat fungal infections that may be contributing to the white discoloration.
  3. Oral Medications: In some cases, oral medications may be prescribed to treat the underlying cause of apparent leukonychia. For example, if the condition is caused by a fungal infection, antifungal medications may be prescribed. If the condition is caused by a nutritional deficiency, supplements may be recommended.
  4. Proper Nail Care: Simple nail care practices can help prevent the formation of white spots on the nails. Keeping the nails clean and dry, avoiding nail biting, and avoiding harsh chemicals can prevent damage to the nails.
  5. Vitamin Supplements: A deficiency in certain vitamins, such as iron, calcium, and biotin, can cause white spots on the nails. Taking supplements or including foods rich in these vitamins in the diet can help improve the condition.
  6. Psoralen and Ultraviolet A (PUVA) Therapy: This therapy is used for patients with psoriasis. PUVA therapy involves taking a medication called psoralen, which makes the skin more sensitive to light. The skin is then exposed to ultraviolet A (UVA) light, which helps to slow down the growth of skin cells and reduce the symptoms of psoriasis.
  7. Topical Corticosteroids: Topical corticosteroids can be used to reduce inflammation and itching caused by psoriasis. These medications are applied directly to the affected skin and can help to improve the appearance of the nails.
  8. Nail Removal: In severe cases of fungal infections, the affected nail may need to be removed. The nail will grow back over time, and the new nail will be free of the infection.
  9. Laser Therapy: Laser therapy can be used to treat fungal infections of the nails. The laser beam is directed at the affected area, killing the fungal cells and promoting the growth of new, healthy cells.
  10. Surgery: In severe cases of psoriasis, surgery may be recommended to remove the affected skin and nails. This procedure is usually performed under local anesthesia and is considered a last resort if other treatments have not been successful.
  11. Surgical Procedures: In severe cases, surgical procedures may be necessary to treat apparent leukonychia. This may include removing the affected portion of the nail or removing the entire nail. In some cases, the nail matrix may need to be removed to allow for regrowth of the nail. These surgical procedures are typically only recommended in severe cases and should be performed by a licensed healthcare provider.
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In conclusion, apparent leukonychia can be treated effectively with the right approach. Consult a doctor if the white spots persist for a long time or if the nails become thick or brittle. A combination of proper nail care, vitamin supplements, and medications can help to improve the condition and prevent the formation of white spots on the nails.

References