Hypertrichosis Simplex of the Scalp

Hypertrichosis simplex of the scalp is a condition characterized by excessive hair growth on the scalp. It is also known as congenital generalized hypertrichosis and is a rare genetic disorder. This condition affects both males and females, and is present at birth.

Hypertrichosis simplex of the scalp is not a dangerous condition, but it can cause cosmetic concerns and affect the individual’s quality of life. The hair growth in this condition is long, thick, and can cover the entire scalp. In some cases, the hair growth may also extend to the forehead, neck, and eyebrows.

Causes

The exact cause of this condition is unknown, but several theories have been proposed. In this article, we will discuss the main causes of hypertrichosis simplex of the scalp.

  1. Genetics

One of the most commonly accepted causes of hypertrichosis simplex of the scalp is genetics. The condition is inherited in an autosomal dominant pattern, meaning that a person only needs one copy of the mutated gene to develop the condition. The gene responsible for hypertrichosis simplex of the scalp has not been identified yet, but researchers are actively working to identify the genetic basis of this condition.

  1. Abnormal Hormonal Balance

Another possible cause of hypertrichosis simplex of the scalp is an abnormal hormonal balance. Hormones play a crucial role in regulating hair growth, and an imbalance in hormones can lead to excessive hair growth. In some cases, hypertrichosis simplex of the scalp may be caused by elevated levels of androgens, which are male hormones that stimulate hair growth.

  1. Abnormal Keratinocyte Function

Keratinocytes are cells that produce keratin, a protein that makes up the hair shaft. Abnormal keratinocyte function can lead to excessive hair growth, and may be a cause of hypertrichosis simplex of the scalp.

  1. Abnormal Stem Cell Function

Stem cells play a crucial role in hair growth by producing new hair follicles. Abnormal stem cell function can lead to excessive hair growth, and may be a cause of hypertrichosis simplex of the scalp.

  1. Environmental Factors

Environmental factors, such as exposure to certain chemicals or radiation, can also cause excessive hair growth. However, this type of hypertrichosis is not hereditary and is typically not associated with hypertrichosis simplex of the scalp.

Hypertrichosis simplex of the scalp is a benign condition and does not cause any other health problems. However, it can be cosmetically distressing for some individuals, and can lead to social stigma and psychological distress.

Symptoms

The main symptoms of hypertrichosis simplex of the scalp include:

  1. Excessive hair growth: The most noticeable symptom of hypertrichosis simplex of the scalp is excessive hair growth in the affected area. The hair is usually dark, thick, and longer than normal hair. The hair growth can be patchy or uniform and can cover the entire scalp.
  2. Early onset: Hypertrichosis simplex of the scalp usually begins to develop in childhood, with the onset of hair growth occurring between the ages of 3 and 7.
  3. Localized hair growth: The hair growth is typically limited to the scalp and does not spread to other parts of the body. In some cases, hair growth may also be present in the eyebrows, lashes, and beard.
  4. No other physical abnormalities: Hypertrichosis simplex of the scalp is a benign condition and does not cause any other physical abnormalities or intellectual impairments.
  5. No change in texture or quality of hair: The hair growth in hypertrichosis simplex of the scalp is usually normal in texture and quality, with no change in its thickness or coarseness.
  6. No itching or discomfort: Unlike other hair growth conditions, hypertrichosis simplex of the scalp does not cause itching or discomfort.
  7. No hair loss: Unlike other hair growth conditions, hypertrichosis simplex of the scalp does not cause hair loss or balding.
  8. No pain or tenderness: The affected area does not experience any pain or tenderness.
  9. No change in skin texture: The skin texture in the affected area remains normal and does not become thick or scaly.
  10. No scarring: Hypertrichosis simplex of the scalp does not cause scarring or permanent changes to the skin.
  11. No treatment necessary: Hypertrichosis simplex of the scalp is a benign condition and does not require treatment. However, some individuals may choose to remove the excess hair for cosmetic reasons.
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Hypertrichosis simplex of the scalp is usually diagnosed based on a physical examination and a review of the patient’s medical history. A biopsy may be performed to confirm the diagnosis, and genetic testing can be used to determine the specific mutation causing the condition.

The condition is inherited in an autosomal dominant pattern, meaning that a person with hypertrichosis simplex of the scalp has a 50% chance of passing the condition on to their children. The condition is not associated with any other medical conditions or intellectual impairments.

Diagnosis

Diagnosis of Hypertrichosis Simplex of the Scalp

The diagnosis of hypertrichosis simplex of the scalp is usually made based on the physical examination of the affected person. The physician will look for the presence of excessive hair growth on the scalp and exclude any underlying medical conditions that may cause hypertrichosis.

Medical History

The physician will take a detailed medical history, including the age of onset, pattern of hair growth, and any family history of excessive hair growth. This information can help to determine if the condition is inherited or acquired.

Physical Examination

A physical examination of the scalp is the most important aspect of the diagnosis. The physician will look for the presence of excessive hair growth on the scalp and examine the hair shafts to determine if they are thick, curly, or pigmented. The physician will also examine the skin to determine if there is any associated skin condition, such as seborrheic dermatitis, which can cause excessive hair growth.

Tests for Hypertrichosis Simplex of the Scalp

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The following tests may be performed to confirm the diagnosis of hypertrichosis simplex of the scalp:

  1. Skin Biopsy

A skin biopsy is a procedure in which a small sample of skin is removed and examined under a microscope. This test can help to determine if there is any underlying skin condition, such as seborrheic dermatitis, that may be contributing to the excessive hair growth.

  1. Blood Tests

Blood tests may be performed to check for hormonal imbalances that may be contributing to the excessive hair growth. The physician may order tests to measure levels of hormones such as testosterone, dihydrotestosterone (DHT), and thyroid hormones.

Treatment

Treatment for hypertrichosis simplex of the scalp may involve medical, surgical, or cosmetic approaches. The choice of treatment will depend on the severity of the condition, the patient’s age, the patient’s personal preferences, and the availability of resources. The following is a list of treatments for hypertrichosis simplex of the scalp:

  1. Shaving

Shaving is the simplest and most straightforward treatment for hypertrichosis simplex of the scalp. This involves removing the excess hair by shaving it off with a razor. This treatment is painless and requires no anesthesia. It is also relatively cheap and can be performed at home. However, the hair will grow back within a few days, so this treatment may need to be repeated on a regular basis.

  1. Depilation

Depilation is a process that involves removing the hair from the surface of the skin without damaging the hair follicle. This can be done using creams, gels, or sprays. Depilation is a good option for those who do not want to undergo surgery or laser hair removal. It is also a good option for those who have sensitive skin and cannot tolerate the pain associated with other treatments. However, the hair will grow back within a few days, so this treatment may need to be repeated on a regular basis.

  1. Electrolysis
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Electrolysis is a process that involves the use of an electrical current to destroy the hair follicle. This treatment is performed by a trained electrologist and requires multiple sessions. It is a good option for those who have a small area of hypertrichosis simplex of the scalp and want a permanent solution. However, electrolysis can be painful and requires a long recovery period. It is also relatively expensive, and the results may vary depending on the individual’s skin type and hair growth pattern.

  1. Laser hair removal

Laser hair removal is a process that involves the use of a laser to destroy the hair follicle. This treatment is performed by a trained dermatologist or laser technician and requires multiple sessions. It is a good option for those who have a large area of hypertrichosis simplex of the scalp and want a permanent solution. Laser hair removal is less painful than electrolysis and has a shorter recovery period. However, it is relatively expensive, and the results may vary depending on the individual’s skin type and hair growth pattern.

  1. Surgical hair transplant

Surgical hair transplant is a process that involves the removal of hair follicles from one area of the scalp and transplanting them to the affected area. This treatment is performed by a trained plastic surgeon and requires a long recovery period. It is a good option for those who have severe hypertrichosis simplex of the scalp and want a permanent solution. However, surgical hair transplant is expensive, and the results may vary depending on the individual’s skin type and hair growth pattern.

  1. Topical medications

Topical medications are creams, gels, or ointments that are applied directly to the affected area. These medications can be used to slow down hair growth or to treat the underlying cause of hypertrichosis simplex of the scalp.

References