Ceftiolene; Uses, Contra indications, Dosage, Side Effects, Interaction ,Pregnancy

Ceftiolene
Sending
User Review
( votes)

Ceftiolene is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiolene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Mechanism of action of Ceftiolene

The bactericidal activity of ceftiolene results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Ceftioleneis highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. Ceftiolene is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiolenebinds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

…………….data or information not available. For further information 

https://pubchem.ncbi.nlm.nih.gov/compound/Ceftiolene

 

Print Friendly, PDF & Email

People Also Reading

You Can Also Like   Hemoglobin; Way to Increase Your Hemoglobin Level

Leave a Reply